| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Iu Ivanova, P H Kostiu. [Chronic treatment with GABA A receptor blockers increases efficacy of GABAergic synaptic transmission in rat hippocampal neuron cultures]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 50. issue 4. 2004-12-22. PMID:15460022. |
[chronic treatment with gaba a receptor blockers increases efficacy of gabaergic synaptic transmission in rat hippocampal neuron cultures]. |
2004-12-22 |
2023-08-12 |
rat |
| Sahruh Turkmen, Per Lundgren, Vita Birzniece, Elisabeth Zingmark, Torbjorn Backstrom, Inga-Maj Johansso. 3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone. The European journal of neuroscience. vol 20. issue 6. 2004-12-20. PMID:15355327. |
the increased chloride ion uptake induced by increasing dosage of allopregnanolone in the presence of 10 micro m gaba was significantly decreased with uc1011 (p < 0.01), in both cortical and hippocampal homogenates. |
2004-12-20 |
2023-08-12 |
rat |
| Sampsa Sipilä, Kristiina Huttu, Juha Voipio, Kai Kail. GABA uptake via GABA transporter-1 modulates GABAergic transmission in the immature hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 26. 2004-12-16. PMID:15229234. |
gaba uptake via gaba transporter-1 modulates gabaergic transmission in the immature hippocampus. |
2004-12-16 |
2023-08-12 |
rat |
| Sampsa Sipilä, Kristiina Huttu, Juha Voipio, Kai Kail. GABA uptake via GABA transporter-1 modulates GABAergic transmission in the immature hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 26. 2004-12-16. PMID:15229234. |
gaba transporter-1 (gat-1) is the main neuronal gaba transporter subtype and is already expressed in the early postnatal rat hippocampus. |
2004-12-16 |
2023-08-12 |
rat |
| Paul Schweitzer, Marisa Roberto, Samuel G Madamba, George Robert Siggin. gamma-hydroxybutyrate increases a potassium current and decreases the H-current in hippocampal neurons via GABAB receptors. The Journal of pharmacology and experimental therapeutics. vol 311. issue 1. 2004-12-15. PMID:15152029. |
in hippocampal neurons, ghb may activate its own putative receptor as well as gaba(b) receptors to affect synaptic transmission. |
2004-12-15 |
2023-08-12 |
rat |
| Marian Brackmann, Congjian Zhao, Volker Schmieden, Karl-Heinz Braunewel. Cellular and subcellular localization of the inhibitory glycine receptor in hippocampal neurons. Biochemical and biophysical research communications. vol 324. issue 3. 2004-12-14. PMID:15485673. |
little is known about the function of glycine receptors in cortex and hippocampus, where gaba plays a dominant role in synaptic inhibition. |
2004-12-14 |
2023-08-12 |
Not clear |
| Lei Shi, Anne Elizabeth Argenta, Adam Kerrissey Winseck, Judy Karen Brunso-Bechtol. Stereological quantification of GAD-67-immunoreactive neurons and boutons in the hippocampus of middle-aged and old Fischer 344 x Brown Norway rats. The Journal of comparative neurology. vol 478. issue 3. 2004-12-02. PMID:15368530. |
five middle-aged (15-17 months) and five old (25-29 months) fischer 344 x brown norway male rats were perfused, and coronal sections through the dorsal hippocampus were immunoreacted with antibodies either to neun, a neuronal marker, or to the 67-kda isoform of glutamic acid decarboxylase (gad), the rate-limiting enzyme for gaba synthesis. |
2004-12-02 |
2023-08-12 |
rat |
| Enrica Maria Petrini, Ivan Marchionni, Paola Zacchi, Werner Sieghart, Enrico Cherubin. Clustering of extrasynaptic GABA(A) receptors modulates tonic inhibition in cultured hippocampal neurons. The Journal of biological chemistry. vol 279. issue 44. 2004-11-30. PMID:15317810. |
clustering of extrasynaptic gaba(a) receptors modulates tonic inhibition in cultured hippocampal neurons. |
2004-11-30 |
2023-08-12 |
Not clear |
| Enrica Maria Petrini, Ivan Marchionni, Paola Zacchi, Werner Sieghart, Enrico Cherubin. Clustering of extrasynaptic GABA(A) receptors modulates tonic inhibition in cultured hippocampal neurons. The Journal of biological chemistry. vol 279. issue 44. 2004-11-30. PMID:15317810. |
we recently reported that, in cultured hippocampal neurons, the clustering of synaptic gaba(a) receptors significantly affects synaptic transmission. |
2004-11-30 |
2023-08-12 |
Not clear |
| Jingyi Ma, Bixia Shen, N Rajakumar, L Stan Leun. The medial septum mediates impairment of prepulse inhibition of acoustic startle induced by a hippocampal seizure or phencyclidine. Behavioural brain research. vol 155. issue 1. 2004-11-15. PMID:15325789. |
the medial septum infusion with muscimol (0.25 microg), a gaba(a) receptor agonist, 15 min prior to pcp or a hippocampal ad, prevented the impairment of sensorimotor gating and the increase in gamma waves. |
2004-11-15 |
2023-08-12 |
rat |
| Jerzy W Mozrzymas, Andrea Barberi. Changes of GABA(A)receptor activation kinetics in hippocampal neurons cultured for different periods of time. Cellular & molecular biology letters. vol 9. issue 1. 2004-11-09. PMID:15048151. |
changes of gaba(a)receptor activation kinetics in hippocampal neurons cultured for different periods of time. |
2004-11-09 |
2023-08-12 |
Not clear |
| Mark C Bieda, M Bruce MacIve. Major role for tonic GABAA conductances in anesthetic suppression of intrinsic neuronal excitability. Journal of neurophysiology. vol 92. issue 3. 2004-11-04. PMID:15140905. |
we propose that for some anesthetics, suppression of intrinsic excitability, mediated by tonic gaba(a) conductances, operates in conjunction with effects on synaptic transmission, mediated by other mechanisms, to depress hippocampal function during anesthesia. |
2004-11-04 |
2023-08-12 |
rat |
| Laura F Martin, William R Kem, Robert Freedma. Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia. Psychopharmacology. vol 174. issue 1. 2004-10-25. PMID:15205879. |
this inhibitory process, which involves the alpha(7) nicotinic receptor mediated release of gamma-aminobutyric acid (gaba) by hippocampal interneurons, represents a potential new target for therapeutic intervention in schizophrenia. |
2004-10-25 |
2023-08-12 |
Not clear |
| Erik I Charych, Wendou Yu, Rongwen Li, David R Serwanski, Celia P Miralles, Xuejing Li, Bih Y Yang, Noelia Pinal, Randall Walikonis, Angel L De Bla. A four PDZ domain-containing splice variant form of GRIP1 is localized in GABAergic and glutamatergic synapses in the brain. The Journal of biological chemistry. vol 279. issue 37. 2004-10-19. PMID:15226318. |
in low density hippocampal cultures, grip1c 4-7 clusters colocalized with gabaergic (where gaba is gamma-aminobutyric acid) and glutamatergic synapses, although a higher percentage of grip1c 4-7 clusters colocalized with gamma-aminobutyric acid, type a, receptor (gaba(a)r) clusters than with alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid receptor clusters. |
2004-10-19 |
2023-08-12 |
rat |
| Erik I Charych, Wendou Yu, Rongwen Li, David R Serwanski, Celia P Miralles, Xuejing Li, Bih Y Yang, Noelia Pinal, Randall Walikonis, Angel L De Bla. A four PDZ domain-containing splice variant form of GRIP1 is localized in GABAergic and glutamatergic synapses in the brain. The Journal of biological chemistry. vol 279. issue 37. 2004-10-19. PMID:15226318. |
transfection of hippocampal neurons with hemagglutinin-tagged grip1c 4-7 showed that it could target to the postsynaptic complex of gabaergic synapses colocalizing with gaba(a)r clusters. |
2004-10-19 |
2023-08-12 |
rat |
| Xiaohong Xu, Yanyue Hu, Qin Rua. Effects of puerarin on learning-memory and amino acid transmitters of brain in ovariectomized mice. Planta medica. vol 70. issue 7. 2004-10-19. PMID:15303253. |
after a behavior test,the levels of glutamate (glu) and gaba in the frontal cortex and hippocampus were assessed using high-performance liquid chromatography (hplc). |
2004-10-19 |
2023-08-12 |
mouse |
| Xiaohong Xu, Yanyue Hu, Qin Rua. Effects of puerarin on learning-memory and amino acid transmitters of brain in ovariectomized mice. Planta medica. vol 70. issue 7. 2004-10-19. PMID:15303253. |
the results showed that 100 mg/kg pur normalized the levels of glu and gaba in the hippocampus of ovx mice, while the glu level was significantly elevated from 24.1+/- 4.5 to 27.9+/- 3.5 mg/g protein (p < 0.05), and gaba was decreased from 5.64+/- 1.06 to 4.73+/- 0.85 mg/g protein (p < 0.05). |
2004-10-19 |
2023-08-12 |
mouse |
| J Wei, M Zhang, Y Zhu, J-H Wan. Ca(2+)-calmodulin signalling pathway up-regulates GABA synaptic transmission through cytoskeleton-mediated mechanisms. Neuroscience. vol 127. issue 3. 2004-10-18. PMID:15283963. |
we investigated the role of calcium (ca(2+))/calmodulin (cam) signaling pathways in modulating gaba synaptic transmission at ca1 pyramidal neurons in hippocampal slices. |
2004-10-18 |
2023-08-12 |
Not clear |
| Floria Pancetti, Marcelo Oyarce, Marcela Aranda, Jorge Parodi, Luis G Aguayo, Bernardo Morales, Götz Westphal, Michael Müller, Ernst Hallier, Marc L Zeis. S-methylcysteine may be a causal factor in monohalomethane neurotoxicity. Neurotoxicology. vol 25. issue 5. 2004-10-18. PMID:15288512. |
using whole-cell patch clamp in hippocampal dissociated neurons we have found that smc (applied for approximately 1s) reduces gaba-induced currents ( ic(50) = 4.4 x 10(-4) m) without having an effect of its own, acting like a competitive antagonist at gaba(a) receptors. |
2004-10-18 |
2023-08-12 |
rat |
| Jia Shu, Rong-Yu Liu, Xian-Fen Huan. The effects of ear-point stimulation on the contents of somatostatin and Amino acid neurotransmitters in brain of rat with experimental seizure. Acupuncture & electro-therapeutics research. vol 29. issue 1-2. 2004-10-18. PMID:15382788. |
based on the results above, it was suggestive that ear-point electrical stimulation had anti-epilepsy effects, which might be involved in the decreases of the contents of the somatostatin, aspartic acid and glutamine, and increases of the contents of glycine, taurine and gaba in hippocampus of seizure rat. |
2004-10-18 |
2023-08-12 |
rat |