| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brian Dean, Elizabeth Scarr, Mark McLeo. Changes in hippocampal GABAA receptor subunit composition in bipolar 1 disorder. Brain research. Molecular brain research. vol 138. issue 2. 2005-11-14. PMID:15950312. |
postmortem cns studies have suggested an uncoupling of the gamma-aminobutyric acid (gaba) and benzodiazepine binding sites on the hippocampal gaba(a) receptor in schizophrenia. |
2005-11-14 |
2023-08-12 |
human |
| Brian Dean, Elizabeth Scarr, Mark McLeo. Changes in hippocampal GABAA receptor subunit composition in bipolar 1 disorder. Brain research. Molecular brain research. vol 138. issue 2. 2005-11-14. PMID:15950312. |
unlike [(3)h]flumazenil, zolpidem does not bind to the alpha5 subunit of the gaba(a) receptor; therefore, we postulate that there is an increase in gaba(a) receptors containing alpha5 subunit in the hippocampus from subjects with bipolar i disorder. |
2005-11-14 |
2023-08-12 |
human |
| Murat Durakoglugil, Andrew J Irving, Jenni Harve. Leptin induces a novel form of NMDA receptor-dependent long-term depression. Journal of neurochemistry. vol 95. issue 2. 2005-11-02. PMID:16086687. |
here we demonstrate that under conditions of enhanced excitability (evoked in mg2+-free medium or following blockade of gaba(a) receptors), leptin induces a novel form of long-term depression (ltd) in area ca1 of the hippocampus. |
2005-11-02 |
2023-08-12 |
Not clear |
| Hui Shen, Qi Hua Gong, Maoli Yuan, Sheryl S Smit. Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: pharmacological and behavioral effects. Neuropharmacology. vol 49. issue 5. 2005-10-31. PMID:15950994. |
in this study, 48 h administration of 3alpha-oh-5beta-pregnan-20-one (3alpha,5beta-thp) or 17beta-estradiol (e2)+progesterone (p) to female rats increased expression of the delta subunit of the gaba(a) receptor (gabar) in ca1 hippocampus. |
2005-10-31 |
2023-08-12 |
rat |
| Stiliani Asimiadou, Petra Bittigau, Ursula Felderhoff-Mueser, Daniela Manthey, Marco Sifringer, Stefanie Pesditschek, Mark Dzietko, Angela M Kaindl, Maria Pytel, Dorota Studniarczyk, Jerzy W Mozrzymas, Chrysanthy Ikonomido. Protection with estradiol in developmental models of apoptotic neurodegeneration. Annals of neurology. vol 58. issue 2. 2005-10-31. PMID:16049923. |
17beta-estradiol did not affect gaba(a) or n-methyl-d-aspartate currents in hippocampal neuronal cultures, indicating that direct modulation of neurotransmitter receptor/channel properties by this compound cannot explain neuroprotective effect. |
2005-10-31 |
2023-08-12 |
rat |
| Araceli Vázquez-López, Germán Sierra-Paredes, Germán Sierra-Marcuñ. Role of cAMP-dependent protein kinase on acute picrotoxin-induced seizures. Neurochemical research. vol 30. issue 5. 2005-10-31. PMID:16176064. |
these results suggest that acute picrotoxin-induced seizures occur without an increase in hippocampal pka activity, but reduced pka-mediated phosphorylation protects against picrotoxin seizures, probably by increasing the inhibitory potential of gaba(a) receptors. |
2005-10-31 |
2023-08-12 |
rat |
| Serap Sirvanci, Charles K Meshul, Filiz Onat, Tangul Sa. Glutamate and GABA immunocytochemical electron microscopy in the hippocampal dentate gyrus of normal and genetic absence epilepsy rats. Brain research. vol 1053. issue 1-2. 2005-10-27. PMID:16038886. |
glutamate and gaba immunocytochemical electron microscopy in the hippocampal dentate gyrus of normal and genetic absence epilepsy rats. |
2005-10-27 |
2023-08-12 |
rat |
| Serap Sirvanci, Charles K Meshul, Filiz Onat, Tangul Sa. Glutamate and GABA immunocytochemical electron microscopy in the hippocampal dentate gyrus of normal and genetic absence epilepsy rats. Brain research. vol 1053. issue 1-2. 2005-10-27. PMID:16038886. |
in particular, besides excessive gaba mediation within the thalamo-cortico-thalamic circuit in absence epilepsy, neuronal networks of the hippocampus have recently received attention. |
2005-10-27 |
2023-08-12 |
rat |
| Serap Sirvanci, Charles K Meshul, Filiz Onat, Tangul Sa. Glutamate and GABA immunocytochemical electron microscopy in the hippocampal dentate gyrus of normal and genetic absence epilepsy rats. Brain research. vol 1053. issue 1-2. 2005-10-27. PMID:16038886. |
in the present study, we examined the density of glutamate and gaba neurotransmitter immunolabeling in the dentate gyrus of the hippocampus of genetic absence epilepsy rats from strasbourg (gaers) compared to the control group. |
2005-10-27 |
2023-08-12 |
rat |
| Marc Danik, Estelle Cassoly, Frédéric Manseau, Florence Sotty, Didier Mouginot, Sylvain William. Frequent coexpression of the vesicular glutamate transporter 1 and 2 genes, as well as coexpression with genes for choline acetyltransferase or glutamic acid decarboxylase in neurons of rat brain. Journal of neuroscience research. vol 81. issue 4. 2005-10-20. PMID:15983996. |
it was revealed using sc-rt-mpcr that transcripts for vglut1 and vglut2 were also present in neurons of the cerebellum, striatum, and septum that expressed markers for gamma-aminobutyric acid (gaba)ergic or cholinergic phenotypes, as well as in hippocampal cells containing transcripts for the glial fibrillary acidic protein. |
2005-10-20 |
2023-08-12 |
rat |
| Fumiaki Mori, Motohiro Okada, Masahiko Tomiyama, Sunao Kaneko, Koichi Wakabayash. Effects of ryanodine receptor activation on neurotransmitter release and neuronal cell death following kainic acid-induced status epilepticus. Epilepsy research. vol 65. issue 1-2. 2005-10-19. PMID:15979854. |
we investigated the ryr-associated effects of cicr agents on basal and k(+)-evoked releases of gaba and glutamate in rat hippocampus and the changes in expression of mrna for ryrs in mouse brain after ka-induced seizures. |
2005-10-19 |
2023-08-12 |
mouse |
| Sébastien J Thuault, Jon T Brown, Andrew R Calver, Graham L Collingridge, Andrew Randall, Ceri H Davie. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit. Epilepsy research. vol 65. issue 1-2. 2005-10-19. PMID:15979855. |
mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a c-terminal truncated gaba(b2) receptor subunit. |
2005-10-19 |
2023-08-12 |
mouse |
| Sébastien J Thuault, Jon T Brown, Andrew R Calver, Graham L Collingridge, Andrew Randall, Ceri H Davie. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit. Epilepsy research. vol 65. issue 1-2. 2005-10-19. PMID:15979855. |
we have previously shown that global loss of gaba(b) receptor function due to transgenic deletion of the gaba(b1) receptor subunit exacerbates epileptiform activity induced by pharmacological manipulations in hippocampal slices. |
2005-10-19 |
2023-08-12 |
mouse |
| Sébastien J Thuault, Jon T Brown, Andrew R Calver, Graham L Collingridge, Andrew Randall, Ceri H Davie. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit. Epilepsy research. vol 65. issue 1-2. 2005-10-19. PMID:15979855. |
here we show that a similar hyperexcitable phenotype is observed in hippocampal slices prepared from a transgenic mouse expressing a gaba(b2) receptor subunit lacking its c terminal tail (the deltagb2-ct mouse); a molecular manipulation that also produces complete loss of gaba(b) receptor function. |
2005-10-19 |
2023-08-12 |
mouse |
| Sébastien J Thuault, Jon T Brown, Andrew R Calver, Graham L Collingridge, Andrew Randall, Ceri H Davie. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit. Epilepsy research. vol 65. issue 1-2. 2005-10-19. PMID:15979855. |
these data suggest that the loss of gaba(b) receptor function in deltagb2-ct hippocampal slices promotes depolarising gaba(a) receptor-mediated events, which in turn, leads to the generation of ictal-like events, which may contribute to the epilepsy phenotype observed in vivo. |
2005-10-19 |
2023-08-12 |
mouse |
| K W Thompso. Genetically engineered cells with regulatable GABA production can affect afterdischarges and behavioral seizures after transplantation into the dentate gyrus. Neuroscience. vol 133. issue 4. 2005-10-11. PMID:15927406. |
cells engineered to produce gaba raised tissue gaba concentrations in the hippocampus compared with non gaba-producing cells, and this was abolished when doxycycline was administered. |
2005-10-11 |
2023-08-12 |
rat |
| K W Thompso. Genetically engineered cells with regulatable GABA production can affect afterdischarges and behavioral seizures after transplantation into the dentate gyrus. Neuroscience. vol 133. issue 4. 2005-10-11. PMID:15927406. |
this study shows that targeted hippocampal implants of genetically engineered cells have the potential to raise gaba levels and to affect seizure development. |
2005-10-11 |
2023-08-12 |
rat |
| Ilona Chudotvorova, Anton Ivanov, Sylvain Rama, Christian A Hübner, Christophe Pellegrino, Yehezkel Ben-Ari, Igor Medin. Early expression of KCC2 in rat hippocampal cultures augments expression of functional GABA synapses. The Journal of physiology. vol 566. issue Pt 3. 2005-10-05. PMID:15961425. |
early expression of kcc2 in rat hippocampal cultures augments expression of functional gaba synapses. |
2005-10-05 |
2023-08-12 |
rat |
| U Iqbal, J F Brien, S Banjanin, M H Andrews, S G Matthews, J N Reynold. Chronic prenatal ethanol exposure alters glucocorticoid signalling in the hippocampus of the postnatal Guinea pig. Journal of neuroendocrinology. vol 17. issue 9. 2005-10-04. PMID:16101899. |
electrically-stimulated release of glutamate and gaba, in the presence or absence of dexamethasone, as well as glucocorticoid and mineralocorticoid receptor mrna expression, was determined in the hippocampus and prefrontal cortex of adult offspring of treated pregnant guinea pigs. |
2005-10-04 |
2023-08-12 |
Not clear |
| U Iqbal, J F Brien, S Banjanin, M H Andrews, S G Matthews, J N Reynold. Chronic prenatal ethanol exposure alters glucocorticoid signalling in the hippocampus of the postnatal Guinea pig. Journal of neuroendocrinology. vol 17. issue 9. 2005-10-04. PMID:16101899. |
chronic prenatal ethanol exposure had no effect on stimulated glutamate or gaba release, but selectively prevented dexamethasone-mediated suppression of stimulated glutamate release, and decreased expression of mineralocorticoid, but not glucocorticoid, receptor mrna in the hippocampus of adult offspring. |
2005-10-04 |
2023-08-12 |
Not clear |