| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eunyoung Kim, Lawrence M Grover, Don Bertolotti, Todd L Gree. Growth hormone rescues hippocampal synaptic function after sleep deprivation. American journal of physiology. Regulatory, integrative and comparative physiology. vol 298. issue 6. 2010-06-15. PMID:20237303. |
in addition, sleep deprivation led to a selective loss of nmda receptor 2b (nr2b) from hippocampal synaptic membranes, but normal nr2b expression was restored by growth hormone injection. |
2010-06-15 |
2023-08-12 |
rat |
| Bernadette M Cortese, Todd R Mitchell, Matthew P Galloway, Kristen E Prevost, Jidong Fang, Gregory J Moore, Thomas W Uhd. Region-specific alteration in brain glutamate: possible relationship to risk-taking behavior. Physiology & behavior. vol 99. issue 4. 2010-05-12. PMID:20006966. |
additionally, sleep deprivation was associated with a significant increase in glutamate levels in the hippocampus and thalamus. |
2010-05-12 |
2023-08-12 |
rat |
| B M Abusho. Morphofunctional analysis of the effects of total sleep deprivation on the CNS in rats. Neuroscience and behavioral physiology. vol 40. issue 4. 2010-04-13. PMID:20339939. |
the aim of the present work was to perform a morphofunctional analysis of the effects of total sleep deprivation of different durations on neuron and synapse ultrastructure in the somnogenic formations (layers iii-v of the anterior limbic cortex, field ca1 of the dorsal hippocampus, the pontine reticular formation, the dorsal cervical nucleus, and the locus ceruleus) in rats, with assessment of study investigative, comfort, and sexual behavior, as well as food and water consumption. |
2010-04-13 |
2023-08-12 |
rat |
| Jean-Etienne Poirrier, François Guillonneau, Jenny Renaut, Kjell Sergeant, Andre Luxen, Pierre Maquet, Pierre Leprinc. Proteomic changes in rat hippocampus and adrenals following short-term sleep deprivation. Proteome science. vol 6. 2009-12-11. PMID:18498662. |
proteomic changes in rat hippocampus and adrenals following short-term sleep deprivation. |
2009-12-11 |
2023-08-12 |
rat |
| Jean-Etienne Poirrier, François Guillonneau, Jenny Renaut, Kjell Sergeant, Andre Luxen, Pierre Maquet, Pierre Leprinc. Proteomic changes in rat hippocampus and adrenals following short-term sleep deprivation. Proteome science. vol 6. 2009-12-11. PMID:18498662. |
to identify the biochemical changes induced by sleep deprivation at a proteomic level, we compared the hippocampal proteome of rats either after 4 hours of sleep or sleep deprivation obtained by gentle handling. |
2009-12-11 |
2023-08-12 |
rat |
| Christopher G Vecsey, George S Baillie, Devan Jaganath, Robbert Havekes, Andrew Daniels, Mathieu Wimmer, Ted Huang, Kim M Brown, Xiang-Yao Li, Giannina Descalzi, Susan S Kim, Tao Chen, Yu-Ze Shang, Min Zhuo, Miles D Houslay, Ted Abe. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature. vol 461. issue 7267. 2009-12-04. PMID:19847264. |
sleep deprivation impairs camp signalling in the hippocampus. |
2009-12-04 |
2023-08-12 |
mouse |
| Christopher G Vecsey, George S Baillie, Devan Jaganath, Robbert Havekes, Andrew Daniels, Mathieu Wimmer, Ted Huang, Kim M Brown, Xiang-Yao Li, Giannina Descalzi, Susan S Kim, Tao Chen, Yu-Ze Shang, Min Zhuo, Miles D Houslay, Ted Abe. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature. vol 461. issue 7267. 2009-12-04. PMID:19847264. |
one of the major effects of sleep deprivation on the brain is to produce memory deficits in learning models that are dependent on the hippocampus. |
2009-12-04 |
2023-08-12 |
mouse |
| Christopher G Vecsey, George S Baillie, Devan Jaganath, Robbert Havekes, Andrew Daniels, Mathieu Wimmer, Ted Huang, Kim M Brown, Xiang-Yao Li, Giannina Descalzi, Susan S Kim, Tao Chen, Yu-Ze Shang, Min Zhuo, Miles D Houslay, Ted Abe. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature. vol 461. issue 7267. 2009-12-04. PMID:19847264. |
here we have identified a molecular mechanism by which brief sleep deprivation alters hippocampal function. |
2009-12-04 |
2023-08-12 |
mouse |
| Christopher G Vecsey, George S Baillie, Devan Jaganath, Robbert Havekes, Andrew Daniels, Mathieu Wimmer, Ted Huang, Kim M Brown, Xiang-Yao Li, Giannina Descalzi, Susan S Kim, Tao Chen, Yu-Ze Shang, Min Zhuo, Miles D Houslay, Ted Abe. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature. vol 461. issue 7267. 2009-12-04. PMID:19847264. |
sleep deprivation selectively impaired 3', 5'-cyclic amp (camp)- and protein kinase a (pka)-dependent forms of synaptic plasticity in the mouse hippocampus, reduced camp signalling, and increased activity and protein levels of phosphodiesterase 4 (pde4), an enzyme that degrades camp. |
2009-12-04 |
2023-08-12 |
mouse |
| Christopher G Vecsey, George S Baillie, Devan Jaganath, Robbert Havekes, Andrew Daniels, Mathieu Wimmer, Ted Huang, Kim M Brown, Xiang-Yao Li, Giannina Descalzi, Susan S Kim, Tao Chen, Yu-Ze Shang, Min Zhuo, Miles D Houslay, Ted Abe. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature. vol 461. issue 7267. 2009-12-04. PMID:19847264. |
these findings demonstrate that brief sleep deprivation disrupts hippocampal function by interfering with camp signalling through increased pde4 activity. |
2009-12-04 |
2023-08-12 |
mouse |
| Matthew P Walke. Cognitive consequences of sleep and sleep loss. Sleep medicine. vol 9 Suppl 1. 2009-09-21. PMID:18929316. |
specifically, one night of sleep deprivation markedly impairs hippocampal function, imposing a deficit in the ability to commit new experiences to memory. |
2009-09-21 |
2023-08-12 |
Not clear |
| Zachary M Weil, Greg J Norman, Kate Karelina, John S Morris, Jacqueline M Barker, Alan J Su, James C Walton, Steven Bohinc, Randy J Nelson, A Courtney DeVrie. Sleep deprivation attenuates inflammatory responses and ischemic cell death. Experimental neurology. vol 218. issue 1. 2009-07-07. PMID:19409382. |
indeed, acute sleep deprivation (asd) was associated with a reduction in ischemia-induced interleukin 1beta (il-1beta) gene expression and attenuation of neuronal damage in the hippocampus. |
2009-07-07 |
2023-08-12 |
mouse |
| B M Abusho. [Morpho-functional analysis of the effect of total sleep deprivation on CNS]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 95. issue 3. 2009-06-22. PMID:19449786. |
the aim of this work was to carry out the morpho-functional analysis of the effect of total sleep deprivation (tsd) of different duration on the ultrastructure of the neurons and the synapses of brain somnogenic structures (iii--v layers of frontal limbic cortex, cai field of dorsal hippocampus, reticular formation of pons varolii, dorsal nucleus raphe and locus coeruleus) in rats as well on exploratory, comfort and sexual behavior and on food and water consumption. |
2009-06-22 |
2023-08-12 |
rat |
| E M Rutskova, M L Pigarev. [Efficiency of the "disk-over-water" method without feedback for sleep deprivation in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 59. issue 2. 2009-06-19. PMID:19445394. |
cortical eeg, hippocampal theta-activity and locomotor activity were recorded in 14 female wistar rats underwent sleep deprivation in the "disk-over-water" setup without feedback. |
2009-06-19 |
2023-08-12 |
rat |
| David N Ruskin, Gerald J LaHost. Reduced-volume cues effectively support fear conditioning despite sleep deprivation. Physiology & behavior. vol 96. issue 1. 2009-04-15. PMID:18775445. |
these results support a pattern of sleep deprivation sparing amygdaloid function but impairing hippocampal function. |
2009-04-15 |
2023-08-12 |
mouse |
| Pascal Ravassard, Bastien Pachoud, Jean-Christophe Comte, Camila Mejia-Perez, Celine Scoté-Blachon, Nadine Gay, Bruno Claustrat, Monique Touret, Pierre-Hervé Luppi, Paul Antoine Sali. Paradoxical (REM) sleep deprivation causes a large and rapidly reversible decrease in long-term potentiation, synaptic transmission, glutamate receptor protein levels, and ERK/MAPK activation in the dorsal hippocampus. Sleep. vol 32. issue 2. 2009-03-30. PMID:19238810. |
paradoxical (rem) sleep deprivation causes a large and rapidly reversible decrease in long-term potentiation, synaptic transmission, glutamate receptor protein levels, and erk/mapk activation in the dorsal hippocampus. |
2009-03-30 |
2023-08-12 |
Not clear |
| Rodrigo N Romcy-Pereira, João P Leite, Norberto Garcia-Cairasc. Synaptic plasticity along the sleep-wake cycle: implications for epilepsy. Epilepsy & behavior : E&B. vol 14 Suppl 1. 2009-02-20. PMID:18926929. |
such modulation, for example, has been shown in the visual cortex following sleep deprivation and in the ability to induce hippocampal long-term potentiation during sleep. |
2009-02-20 |
2023-08-12 |
Not clear |
| Rui-Hua Yang, San-Jue Hu, Yuan Wang, Wen-Bin Zhang, Wen-Jing Luo, Jing-Yuan Che. Paradoxical sleep deprivation impairs spatial learning and affects membrane excitability and mitochondrial protein in the hippocampus. Brain research. vol 1230. 2008-12-05. PMID:18674519. |
paradoxical sleep deprivation impairs spatial learning and affects membrane excitability and mitochondrial protein in the hippocampus. |
2008-12-05 |
2023-08-12 |
rat |
| Rui-Hua Yang, San-Jue Hu, Yuan Wang, Wen-Bin Zhang, Wen-Jing Luo, Jing-Yuan Che. Paradoxical sleep deprivation impairs spatial learning and affects membrane excitability and mitochondrial protein in the hippocampus. Brain research. vol 1230. 2008-12-05. PMID:18674519. |
modulating the excitability of hippocampal neurons and protecting mitochondrial function are possible targets for preventing the effects of paradoxical sleep deprivation. |
2008-12-05 |
2023-08-12 |
rat |
| Ricardo Borges Machado, Sergio Tufik, Deborah Sucheck. Chronic stress during paradoxical sleep deprivation increases paradoxical sleep rebound: association with prolactin plasma levels and brain serotonin content. Psychoneuroendocrinology. vol 33. issue 9. 2008-11-25. PMID:18674865. |
moreover, paradoxical sleep deprivation resulted in elevation of the serotonergic turnover in the hypothalamus, which partly explained the hormonal results, and in the hippocampus, which appears to be related to adaptive responses to stress. |
2008-11-25 |
2023-08-12 |
rat |