| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Köhler, V Chan-Palay, H Steinbusc. The distribution and origin of serotonin-containing fibers in the septal area: a combined immunohistochemical and fluorescent retrograde tracing study in the rat. The Journal of comparative neurology. vol 209. issue 1. 1982-12-02. PMID:6749914. |
intraseptal injections of hrp or fluorescent dyes (granular blue, propidium iodide) resulted in retrograde labeling of neuronal cell bodies in several nuclei of the brainstem which are known to contain 5-ht neurons: the dorsal raphe, the median raphe, the nucleus reticularis tegmenti pontis, the raphe pontis, and the raphe magnus. |
1982-12-02 |
2023-08-12 |
rat |
| S L Dickinson, P Slate. Effect of lesioning dopamine, noradrenaline and 5-hydroxytryptamine pathways on tremorine-induced tremor and rigidity. Neuropharmacology. vol 21. issue 8. 1982-12-02. PMID:7121751. |
a median raphe electrolytic lesion affecting 5-hydroxytryptamine (5-ht) neurones had no effect on tremor and rigidity, whereas lesioning the dorsal raphe electrolytically or by injecting 5,6-dihydroxytryptamine prevented rigidity without affecting tremor. |
1982-12-02 |
2023-08-12 |
rat |
| T D Reisine, P Soubrié, F Artaud, J Glowinsk. Involvement of lateral habenula-dorsal raphe neurons in the differential regulation of striatal and nigral serotonergic transmission cats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 8. 1982-10-21. PMID:6180148. |
[3h]serotonin was measured in both caudate nuclei and substantiae nigra and, in some cases, in the dorsal raphe. |
1982-10-21 |
2023-08-12 |
cat |
| T D Reisine, P Soubrié, F Artaud, J Glowinsk. Involvement of lateral habenula-dorsal raphe neurons in the differential regulation of striatal and nigral serotonergic transmission cats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 8. 1982-10-21. PMID:6180148. |
blockade of the gaba inhibitory pathway to the lateral habenula by the local application of picrotoxin reduced [3h]serotonin release in both substantiae nigra and increased release of the 3h-amine in the dorsal raphe but was without effect on [3h]serotonin release in either caudate nucleus. |
1982-10-21 |
2023-08-12 |
cat |
| T D Reisine, P Soubrié, F Artaud, J Glowinsk. Involvement of lateral habenula-dorsal raphe neurons in the differential regulation of striatal and nigral serotonergic transmission cats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 8. 1982-10-21. PMID:6180148. |
this inhibition of nigral [3h]serotonin release was antagonized by simultaneous application of picrotoxin to the dorsal raphe. |
1982-10-21 |
2023-08-12 |
cat |
| T D Reisine, P Soubrié, F Artaud, J Glowinsk. Involvement of lateral habenula-dorsal raphe neurons in the differential regulation of striatal and nigral serotonergic transmission cats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 8. 1982-10-21. PMID:6180148. |
substance p delivery to the dorsal raphe produced the same effects on [3h]serotonin release as described for picrotoxin application to the lateral habenula except that inhibition of nigral [3h]serotonin release was not prevented by local co-administration of picrotoxin. |
1982-10-21 |
2023-08-12 |
cat |
| M A Geyer, C E Flicker, E H Le. Effects of tactile startle on serotonin content of midbrain raphe neurons in rats. Behavioural brain research. vol 4. issue 4. 1982-07-19. PMID:7073886. |
a series of 240 air puff stimuli given in 1 h immediately before sacrifice decreased the intracellular 5-ht content, as measured by microspectrofluorimetry, in the median raphe nucleus, without affecting 5-ht levels in the dorsal raphe nucleus. |
1982-07-19 |
2023-08-12 |
rat |
| S Consolo, H Ladinsky, G L Forloni, P Gromb. Modulation of the hippocampal alpha-adrenoceptor population by lesion of the serotonergic raphe-hippocampal pathway in rats. Life sciences. vol 30. issue 13. 1982-07-08. PMID:6281602. |
electrolytic lesion of the ascending serotonergic fibers in the median raphe nucleus or in both the median raphe nucleus and dorsal raphe nucleus caused after 18 days more than 80% depletion of serotonin in the hippocampus and frontal cortex, respectively, without affecting norepinephrine and acetylcholine contents. |
1982-07-08 |
2023-08-12 |
rat |
| R I Cone, G A Davis, R W Go. Effects of ovarian steroids on serotonin metabolism within grossly dissected and microdissected brain regions of the ovariectomized rat. Brain research bulletin. vol 7. issue 6. 1982-04-12. PMID:7326580. |
brain serotonin (5-ht) levels and accumulation rate within the dorsal raphe nucleus (dr) were elevated in ovariectomized (ovx) rats after ovarian steroid treatment, which consisted of estradiol benzoate (eb) followed by progesterone (p) 48 hr later. |
1982-04-12 |
2023-08-12 |
rat |
| D van der Kooy, S P Hunt, H W Steinbusch, A A Verhofsta. Separate populations of cholecystokinin and 5-hydroxytryptamine-containing neuronal cells in the rat dorsal raphe, and their contribution to the ascending raphe projections. Neuroscience letters. vol 26. issue 1. 1981-12-21. PMID:6270603. |
successive immunohistofluorescent staining for cholecystokinin and 5-hydroxytryptamine (5-ht) was combined with fluorescent retrograde axonal tracing to analyze ascending projections from the rat dorsal raphe nucleus. |
1981-12-21 |
2023-08-12 |
rat |
| M A Rogawski, G K Aghajania. Serotonin autoreceptors on dorsal raphe neurons: structure-activity relationships of tryptamine analogs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 1. issue 10. 1981-12-21. PMID:6793698. |
serotonin autoreceptors on dorsal raphe neurons: structure-activity relationships of tryptamine analogs. |
1981-12-21 |
2023-08-12 |
rat |
| H Fujiwara, M Uemoto, C Tanak. Stimulation of the rat dorsal raphe in vivo releases labeled serotonin from the parietal cortex. Brain research. vol 216. issue 2. 1981-09-25. PMID:7248780. |
stimulation of the rat dorsal raphe in vivo releases labeled serotonin from the parietal cortex. |
1981-09-25 |
2023-08-12 |
rat |
| H Fujiwara, M Uemoto, C Tanak. Stimulation of the rat dorsal raphe in vivo releases labeled serotonin from the parietal cortex. Brain research. vol 216. issue 2. 1981-09-25. PMID:7248780. |
stimulation of the rostral two-thirds of the dorsal raphe and the lateral 5-ht bundle originating from the dorsal raphe significantly increased the release of [3h]5-ht and its metabolites while stimulation of the caudal one-third of the dorsal raphe did not produce a significant increase in the release of [3h]5-ht and its metabolites. |
1981-09-25 |
2023-08-12 |
rat |
| H Fujiwara, M Uemoto, C Tanak. Stimulation of the rat dorsal raphe in vivo releases labeled serotonin from the parietal cortex. Brain research. vol 216. issue 2. 1981-09-25. PMID:7248780. |
these findings are a direct demonstration of the in vivo release of [3h]5-ht from the parietal cortex with stimulation of the dorsal raphe, particularly the rostral two-thirds of the nucleus and provide the neurochemical evidence for the dorsal raphe-cortical 5-ht pathway via the lateral 5-ht bundle. |
1981-09-25 |
2023-08-12 |
rat |
| J M Baraban, G K Aghajania. Noradrenergic innervation of serotonergic neurons in the dorsal raphe: demonstration by electron microscopic autoradiography. Brain research. vol 204. issue 1. 1981-09-22. PMID:6166350. |
[3h]5-ht em autoradiography of the dorsal raphe produced labelling of cell bodies, dendrites and axons but labelled terminals with synaptic junctions were not observed. |
1981-09-22 |
2023-08-12 |
Not clear |
| J M Baraban, G K Aghajania. Noradrenergic innervation of serotonergic neurons in the dorsal raphe: demonstration by electron microscopic autoradiography. Brain research. vol 204. issue 1. 1981-09-22. PMID:6166350. |
these findings suggest that ne terminals directly innervate 5-ht cells in the dorsal raphe. |
1981-09-22 |
2023-08-12 |
Not clear |
| M Sette, R Raisman, M Briley, S Z Lange. Localisation of tricyclic antidepressant binding sites on serotonin nerve terminals. Journal of neurochemistry. vol 37. issue 1. 1981-09-22. PMID:7252512. |
electrolytic lesions of the rat dorsal raphe, which resulted in a significant decrease in the endogenous levels of serotonin produced a reduction in the density of [3h]imipramine binding sites in the hypothalamus and cortex. |
1981-09-22 |
2023-08-12 |
rat |
| S Pradhan, G Hanson, W Lovenber. Inverse relation of substance P-like immunoreactivity in dorsal raphe nucleus to serotonin levels in pons-medulla following administration of cocaine and 5-hydroxytryptophan. Biochemical pharmacology. vol 30. issue 10. 1981-09-15. PMID:6167271. |
inverse relation of substance p-like immunoreactivity in dorsal raphe nucleus to serotonin levels in pons-medulla following administration of cocaine and 5-hydroxytryptophan. |
1981-09-15 |
2023-08-12 |
Not clear |
| T P Blackburn, B Cox, C G Heapy, T F Lee, D N Middlemis. Supersensitivity of nigral serotonin receptors and rat rotational behaviour. European journal of pharmacology. vol 71. issue 2-3. 1981-09-15. PMID:7250194. |
direct injections of 5-hydroxytryptamine (5-ht) into the corpus striatum (cs) and substantia nigra (sn) after unilateral 5,7-dihydroxytryptamine (5,7-dht) of the dorsal raphe nucleus (drn), resulted in a significant dose related contralateral turning behaviour in sn-injected but not in cs-injected animals. |
1981-09-15 |
2023-08-12 |
rat |
| W A Wolf, D M Kuhn, W Lovenber. Pressor effects of dorsal raphe stimulation and intrahypothalamic application of serotonin in the spontaneously hypertensive rat. Brain research. vol 208. issue 1. 1981-05-28. PMID:7470921. |
pressor effects of dorsal raphe stimulation and intrahypothalamic application of serotonin in the spontaneously hypertensive rat. |
1981-05-28 |
2023-08-12 |
rat |