| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Volk, N Kirchgässne. Damage of Purkinje cell axons following chronic phenytoin administration: an animal model of distal axonopathy. Acta neuropathologica. vol 67. issue 1-2. 1985-09-23. PMID:4024872. |
semi-thin sections and electron microscopy of the cerebellar vermis revealed marked dystrophic changes in the purkinje cell axons. |
1985-09-23 |
2023-08-11 |
mouse |
| G Bernocchi, S Barn. On the heterogeneity of Purkinje neurons in vertebrates. Cytochemical and morphological studies of chromatin during eel (Anguilla anguilla L.) life cycle. Journal fur Hirnforschung. vol 26. issue 2. 1985-09-19. PMID:2410490. |
the relationship between the heterogeneity of purkinje cell chromatin and the functional involvement of cerebellum has been analyzed comparing two stages of eel life cycle (yellow eel and silver eel) which are characterized by a different degree of swimming activity. |
1985-09-19 |
2023-08-11 |
Not clear |
| K Herrup, R Wetts, T J Digli. Cell lineage relationships in the development of the mammalian CNS. II. Bilateral independence of CNS clones. Journal of neurogenetics. vol 1. issue 4. 1985-09-19. PMID:6536730. |
of 6 animals examined in the purkinje cell study, 5 showed left/right differences in the clonal composition of the cerebellum. |
1985-09-19 |
2023-08-12 |
mouse |
| P C Bickford, B J Hoffer, R Freedma. Interaction of norepinephrine with Purkinje cell responses to cerebellar afferent inputs in aged rats. Neurobiology of aging. vol 6. issue 2. 1985-09-11. PMID:4022233. |
interaction of norepinephrine with purkinje cell responses to cerebellar afferent inputs in aged rats. |
1985-09-11 |
2023-08-11 |
rat |
| P C Bickford, B J Hoffer, R Freedma. Interaction of norepinephrine with Purkinje cell responses to cerebellar afferent inputs in aged rats. Neurobiology of aging. vol 6. issue 2. 1985-09-11. PMID:4022233. |
in this investigation complex spike excitation, simple spike excitation, and inhibition of purkinje cell discharge were elicited by stimulation of climbing fibers, mossy fibers, and cerebellar parallel fibers, and quantified by computing post-stimulus time histograms of the neuronal response, recorded extracellularly. |
1985-09-11 |
2023-08-11 |
rat |
| H Kimura, K Okamoto, Y Saka. Pharmacological characterization of postsynaptic receptors for excitatory amino acids in Purkinje cell dendrites in the guinea pig cerebellum. Journal of pharmacobio-dynamics. vol 8. issue 2. 1985-08-06. PMID:2861267. |
pharmacological characterization of postsynaptic receptors for excitatory amino acids in purkinje cell dendrites in the guinea pig cerebellum. |
1985-08-06 |
2023-08-11 |
Not clear |
| H Kimura, K Okamoto, Y Saka. Pharmacological characterization of postsynaptic receptors for excitatory amino acids in Purkinje cell dendrites in the guinea pig cerebellum. Journal of pharmacobio-dynamics. vol 8. issue 2. 1985-08-06. PMID:2861267. |
the responses of purkinje cell dendrites to iontophoretically applied l-glutamate, l-aspartate, kainate and quisqualate were intradendritically recorded in the in vitro slice preparation of the guinea pig cerebellum. |
1985-08-06 |
2023-08-11 |
Not clear |
| H Kimura, K Okamoto, Y Saka. Pharmacological characterization of postsynaptic receptors for excitatory amino acids in Purkinje cell dendrites in the guinea pig cerebellum. Journal of pharmacobio-dynamics. vol 8. issue 2. 1985-08-06. PMID:2861267. |
thus, kainate and quisqualate receptors were certainly present, while there appeared to be no nmda-preferring receptor in purkinje cell dendrites in the guinea pig cerebellum. |
1985-08-06 |
2023-08-11 |
Not clear |
| R Gardette, M Debono, J L Dupont, F Crepe. Electrophysiological studies on the postnatal development of intracerebellar nuclei neurons in rat cerebellar slices maintained in vitro. I. Postsynaptic potentials. Brain research. vol 351. issue 1. 1985-06-25. PMID:2986789. |
it has been shown that functional excitatory synapses are present on these neurons from birth, probably due to climbing and/or mossy fiber collaterals; functional inhibitory synapses, due to monosynaptic projections of purkinje cell axons onto intracerebellar nuclei, are present as early as postnatal day 2; and a more complex pattern of synaptic responses, including short latency excitatory postsynaptic potentials (epsps) and inhibitory postsynaptic potentials (ipsps), longer latency ipsps, and late depolarizing responses, can be elicited in nuclear neurons as early as postnatal day 3, indicating an early development of some complete functional cerebellar circuits involving the intracerebellar nuclei. |
1985-06-25 |
2023-08-11 |
rat |
| H Kimura, K Okamoto, Y Saka. Modulatory effects of prostaglandin D2, E2 and F2 alpha on the postsynaptic actions of inhibitory and excitatory amino acids in cerebellar Purkinje cell dendrites in vitro. Brain research. vol 330. issue 2. 1985-06-13. PMID:2859088. |
for the purpose of revealing the physiological functions or roles of prostaglandins (pgs), pgd2 in particular, in the central nervous system, the effects of pgd2, e2 and f2 alpha on the postsynaptic actions of gaba, taurine, l-glutamate and l-aspartate on purkinje cell dendrites in guinea pig, cerebellar slices were electrophysiologically investigated using intradendritic recording. |
1985-06-13 |
2023-08-11 |
Not clear |
| S Maruyama, G Zhang, Y Tamura, T Yamakuni, Y Takahash. Involvement of spot 35 protein, a cerebellar protein, in modulation of Purkinje cell activity of the rat cerebellum. European journal of pharmacology. vol 108. issue 3. 1985-06-13. PMID:2985403. |
involvement of spot 35 protein, a cerebellar protein, in modulation of purkinje cell activity of the rat cerebellum. |
1985-06-13 |
2023-08-11 |
rat |
| O Robain, L Lanfumey, J Adrien, E Farka. Developmental changes in the cerebellar cortex after locus ceruleus lesion with 6-hydroxydopamine in the rat. Experimental neurology. vol 88. issue 1. 1985-05-21. PMID:2984040. |
significant modifications in cerebellum maturation were observed, mainly a regression failure in the perisomatic purkinje cell processes in the depth of the fissura prima of 10-day-old rats, a reduction in the whole vermis surface area and in the total number of internal granule cells at 15 days of age, the number of external granule cells was slightly enhanced. |
1985-05-21 |
2023-08-11 |
rat |
| L Mancini, M Bertossi, L Roncal. [Differentiation of cerebellar Purkinje neurons of the normal and chronically hypoxic chick embryo]. Bollettino della Societa italiana di biologia sperimentale. vol 61. issue 1. 1985-05-10. PMID:3978001. |
a microscopical and ultrastructural study on the cerebellum development, with peculiar attention to the purkinje cell differentiation, has been undertaken in chick embryos from the 8th incubation day (i.d.) |
1985-05-10 |
2023-08-11 |
chicken |
| L D Stuart, H W Leipol. Lesions in bovine progressive degenerative myeloencephalopathy ("Weaver") of Brown Swiss cattle. Veterinary pathology. vol 22. issue 1. 1985-04-05. PMID:3976130. |
cerebellar lesions were limited to selective degeneration and loss of purkinje cells and occasional swelling of purkinje cell axons (torpedos) in the granular layer of the cerebellar cortex. |
1985-04-05 |
2023-08-11 |
cattle |
| N J Ura. Early stages in the formation of the cerebellum in the frog. The Journal of comparative neurology. vol 232. issue 1. 1985-04-01. PMID:3871798. |
in subsequent weeks, the area of differentiation continued to spread and a purkinje cell layer became established along the dorsal margin of the cerebellar plate. |
1985-04-01 |
2023-08-11 |
Not clear |
| G J Blatt, L M Eisenma. A qualitative and quantitative light microscopic study of the inferior olivary complex of normal, reeler, and weaver mutant mice. The Journal of comparative neurology. vol 232. issue 1. 1985-04-01. PMID:3973080. |
purkinje cell counts revealed that the midline vermal region is the most affected area in the cerebellum in wv/+ and wv/wv whereas counts in the lateral hemisphere are near normal. |
1985-04-01 |
2023-08-11 |
mouse |
| M Kornfeld, B M Woodfin, L Papile, L E Davis, L R Bernar. Neuropathology of ornithine carbamyl transferase deficiency. Acta neuropathologica. vol 65. issue 3-4. 1985-04-01. PMID:3976361. |
in the other case, a girl who died at the age of 2 3/12 years, the brain showed metabolic gliosis in typical location, widespread ulegyria, and moderate atrophy of the internal granular layer in the cerebellum accompanied by development of expansions of purkinje cell dendrites. |
1985-04-01 |
2023-08-11 |
Not clear |
| M Thomasset, A Rabie, O Parkes, C Desplan, D Henin, P Cuisinier-Gleize. Vitamin D-dependent calcium-binding protein in the cerebellum: a marker of Purkinje cell development. Developmental pharmacology and therapeutics. vol 7 Suppl 1. 1985-03-14. PMID:6518972. |
vitamin d-dependent calcium-binding protein in the cerebellum: a marker of purkinje cell development. |
1985-03-14 |
2023-08-12 |
Not clear |
| F J Seil, A L Leima. Evidence against neurotransmitter mediation of sprouting in granuloprival cerebellar cultures. Experimental neurology. vol 87. issue 2. 1985-03-06. PMID:2857127. |
cerebellar cultures derived from neonatal mice undergo a remarkable sprouting of purkinje cell recurrent axon collaterals after exposure for the 1st 5 days in vitro to cytosine arabinoside to destroy granule cells. |
1985-03-06 |
2023-08-11 |
mouse |
| M R Palmer, H Björklund, D A Taylor, A Seiger, L Olson, B J Hoffe. Chronic lead exposure of the developing brain: electrophysiological abnormalities of cerebellar Purkinje neurons. Neurotoxicology. vol 5. issue 3. 1985-03-05. PMID:6151635. |
moderate systemic doses (2 mg/kg) did cause a persistent slowing of purkinje neuron firing rates; however, this effect was much smaller than in intraocular cerebellar grafts. |
1985-03-05 |
2023-08-12 |
Not clear |