| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vikram G Shakkotta. Physiologic changes associated with cerebellar dystonia. Cerebellum (London, England). vol 13. issue 5. 2015-05-20. PMID:24879387. |
this review will discuss the idea of whether in some cases, ataxia and dystonia lie in the same clinical spectrum and whether graded perturbations in cerebellar function may explain a similar causative role for the cerebellum in these two different motor disorders. |
2015-05-20 |
2023-08-13 |
Not clear |
| Anne-Marie Dogonowski, Kasper Winther Andersen, Kristoffer Hougaard Madsen, Per Soelberg Sørensen, Olaf Bjarne Paulson, Morten Blinkenberg, Hartwig Roman Siebne. Multiple sclerosis impairs regional functional connectivity in the cerebellum. NeuroImage. Clinical. vol 4. 2015-05-19. PMID:24371795. |
in patients, two clusters in the left posterior cerebellum expressed a reduction in regional homogeneity with increasing global disability as reflected by the expanded disability status scale (edss) score or higher ataxia scores. |
2015-05-19 |
2023-08-12 |
Not clear |
| Anne-Marie Dogonowski, Kasper Winther Andersen, Kristoffer Hougaard Madsen, Per Soelberg Sørensen, Olaf Bjarne Paulson, Morten Blinkenberg, Hartwig Roman Siebne. Multiple sclerosis impairs regional functional connectivity in the cerebellum. NeuroImage. Clinical. vol 4. 2015-05-19. PMID:24371795. |
these findings suggest a link between impaired regional integration in the cerebellum and general disability and ataxia. |
2015-05-19 |
2023-08-12 |
Not clear |
| Brianna Vaa, Manish Kohli, Katharine A Price, Keith Mark Swet. Solitary cystic cerebellar metastasis in a patient with invasive transitional cell carcinoma of the bladder. BMJ case reports. vol 2014. 2015-05-14. PMID:24920508. |
we report a case of a patient with a history of tcc who presented with lethargy and ataxia and was found to have a solitary cystic cerebellar lesion consistent with metastatic disease. |
2015-05-14 |
2023-08-13 |
Not clear |
| S K Chhetri, D Gow, S Shaunak, A Varm. Clinical assessment of the sensory ataxias; diagnostic algorithm with illustrative cases. Practical neurology. vol 14. issue 4. 2015-05-13. PMID:24570476. |
ataxia is a common neurological syndrome resulting from cerebellar, vestibular or sensory disorders. |
2015-05-13 |
2023-08-12 |
Not clear |
| Jose Bras, Isabel Alonso, Clara Barbot, Maria Manuela Costa, Lee Darwent, Tatiana Orme, Jorge Sequeiros, John Hardy, Paula Coutinho, Rita Guerreir. Mutations in PNKP cause recessive ataxia with oculomotor apraxia type 4. American journal of human genetics. vol 96. issue 3. 2015-05-12. PMID:25728773. |
hereditary autosomal-recessive cerebellar ataxias are a genetically and clinically heterogeneous group of disorders. |
2015-05-12 |
2023-08-13 |
Not clear |
| Marie K Bosch, Jeanne M Nerbonne, David M Ornit. Dual transgene expression in murine cerebellar Purkinje neurons by viral transduction in vivo. PloS one. vol 9. issue 8. 2015-04-24. PMID:25093726. |
viral-vector mediated gene transfer to cerebellar purkinje neurons in vivo is a promising avenue for gene therapy of cerebellar ataxias and for genetic manipulation in functional studies of animal models of cerebellar disease. |
2015-04-24 |
2023-08-13 |
mouse |
| Zeba Siddiqi, Ritu Karoli, Jalees Fatima, Rahul Dey, Khursheed Kazm. A case of cerebellar dysarthria as the presenting symptom of HIV infection. The Journal of the Association of Physicians of India. vol 62. issue 8. 2015-04-24. PMID:25856948. |
a week later he developed ataxia and bilateral cerebellar signs including intention tremors, dysmetria and dysdiadokokinesia. |
2015-04-24 |
2023-08-13 |
human |
| M Mancuso, D Orsucci, G Siciliano, U Bonuccell. The genetics of ataxia: through the labyrinth of the Minotaur, looking for Ariadne's thread. Journal of neurology. vol 261 Suppl 2. 2015-04-20. PMID:25145890. |
among the hereditary cerebellar ataxias (cas), there are at least 36 different forms of autosomal dominant cerebellar ataxia (adcas), 20 autosomal recessive cerebellar ataxias (arcas), two x-linked ataxias, and several forms of ataxia associated with mitochondrial defects. |
2015-04-20 |
2023-08-13 |
Not clear |
| M Mancuso, D Orsucci, G Siciliano, U Bonuccell. The genetics of ataxia: through the labyrinth of the Minotaur, looking for Ariadne's thread. Journal of neurology. vol 261 Suppl 2. 2015-04-20. PMID:25145890. |
moreover, in daily clinical practice, ataxia may present as an isolated cerebellar syndrome or, more often, it is associated with a broad spectrum of neurological manifestations including pyramidal, extrapyramidal, sensory, and cognitive dysfunction. |
2015-04-20 |
2023-08-13 |
Not clear |
| M Strupp, O Kremmyda, C Adamczyk, N Böttcher, C Muth, C W Yip, T Bremov. Central ocular motor disorders, including gaze palsy and nystagmus. Journal of neurology. vol 261 Suppl 2. 2015-04-20. PMID:25145891. |
gaze-evoked nystagmus (gen) in all directions indicates a cerebellar dysfunction and can have multiple causes such as drugs, in particular antiepileptics, chronic alcohol abuse, neurodegenerative cerebellar disorders or cerebellar ataxias; purely vertical gen is due to a midbrain lesion, while purely horizontal gen is due to a pontomedullary lesion. |
2015-04-20 |
2023-08-13 |
Not clear |
| Sérgio B Sousa, Fabiana Ramos, Paula Garcia, Rui P Pais, Catarina Paiva, Philip L Beales, Gudrun E Moore, Jorge M Saraiva, Raoul C M Henneka. Intellectual disability, coarse face, relative macrocephaly, and cerebellar hypotrophy in two sisters. American journal of medical genetics. Part A. vol 164A. issue 1. 2015-04-13. PMID:24501761. |
we report on two portuguese sisters with a very similar phenotype characterized by severe intellectual disability, absent speech, relative macrocephaly, coarse face, cerebellar hypotrophy, and severe ataxia. |
2015-04-13 |
2023-08-12 |
Not clear |
| Ketil Heimdal, Monica Sanchez-Guixé, Ingvild Aukrust, Jens Bollerslev, Ove Bruland, Greg Eigner Jablonski, Anne Kjersti Erichsen, Einar Gude, Jeanette A Koht, Sigrid Erdal, Torunn Fiskerstrand, Bjørn Ivar Haukanes, Helge Boman, Lise Bjørkhaug, Chantal M E Tallaksen, Per M Knappskog, Stefan Johansso. STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity. Orphanet journal of rare diseases. vol 9. 2015-03-30. PMID:25258038. |
a subset of hereditary cerebellar ataxias is inherited as autosomal recessive traits (arcas). |
2015-03-30 |
2023-08-13 |
Not clear |
| Ketil Heimdal, Monica Sanchez-Guixé, Ingvild Aukrust, Jens Bollerslev, Ove Bruland, Greg Eigner Jablonski, Anne Kjersti Erichsen, Einar Gude, Jeanette A Koht, Sigrid Erdal, Torunn Fiskerstrand, Bjørn Ivar Haukanes, Helge Boman, Lise Bjørkhaug, Chantal M E Tallaksen, Per M Knappskog, Stefan Johansso. STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity. Orphanet journal of rare diseases. vol 9. 2015-03-30. PMID:25258038. |
classification of recessive ataxias due to phenotypic differences in the cerebellum and cerebellar structures is constantly evolving due to new identified disease genes. |
2015-03-30 |
2023-08-13 |
Not clear |
| Marie-Lorraine Monin, Sophie Tezenas du Montcel, Cecilia Marelli, Cecile Cazeneuve, Perrine Charles, Chantal Tallaksen, Sylvie Forlani, Giovanni Stevanin, Alexis Brice, Alexandra Dur. Survival and severity in dominant cerebellar ataxias. Annals of clinical and translational neurology. vol 2. issue 2. 2015-03-09. PMID:25750924. |
survival and severity in dominant cerebellar ataxias. |
2015-03-09 |
2023-08-13 |
Not clear |
| Naohisa Ueda, Yasuhito Hakii, Shigeru Koyano, Yuichi Higashiyama, Hideto Joki, Yasuhisa Baba, Yume Suzuki, Yoshiyuki Kuroiwa, Fumiaki Tanak. Quantitative analysis of upper-limb ataxia in patients with spinocerebellar degeneration. Journal of neurology. vol 261. issue 7. 2015-03-02. PMID:24781836. |
ataxia was rated using the scale for the assessment and rating of ataxia (sara) and cerebellar volume was evaluated in 37 patients using an axial cross-section of magnetic resonance images that were obtained within 6 months of clinical evaluation. |
2015-03-02 |
2023-08-13 |
Not clear |
| Sonia Bonnì, Viviana Ponzo, Carlo Caltagirone, Giacomo Koc. Cerebellar theta burst stimulation in stroke patients with ataxia. Functional neurology. vol 29. issue 1. 2015-02-23. PMID:25014048. |
cerebellar theta burst stimulation in stroke patients with ataxia. |
2015-02-23 |
2023-08-13 |
Not clear |
| Parminder J S Vig, Scoty M Hearst, Qingmei Shao, Maripar E Lope. Knockdown of acid-sensing ion channel 1a (ASIC1a) suppresses disease phenotype in SCA1 mouse model. Cerebellum (London, England). vol 13. issue 4. 2015-02-09. PMID:24788087. |
the mutated ataxin-1 protein in spinocerebellar ataxia 1 (sca1) targets purkinje cells (pcs) of the cerebellum and causes progressive ataxia due to loss of pcs and neurons of the brainstem. |
2015-02-09 |
2023-08-13 |
mouse |
| Chia-Feng Lu, Po-Shan Wang, Yuan-Lin Lao, Hsiu-Mei Wu, Bing-Wen Soong, Yu-Te W. Medullo-ponto-cerebellar white matter degeneration altered brain network organization and cortical morphology in multiple system atrophy. Brain structure & function. vol 219. issue 3. 2015-02-04. PMID:23636223. |
impairment of the cerebellum can cause ataxia and cerebellar cognitive affective syndrome. |
2015-02-04 |
2023-08-12 |
Not clear |
| Xin Guan, Yanhong Duan, Qingwen Zeng, Hongjie Pan, Yu Qian, Dali Li, Xiaohua Cao, Mingyao Li. Lgr4 protein deficiency induces ataxia-like phenotype in mice and impairs long term depression at cerebellar parallel fiber-Purkinje cell synapses. The Journal of biological chemistry. vol 289. issue 38. 2015-02-02. PMID:25063812. |
cerebellar dysfunction causes ataxia characterized by loss of balance and coordination. |
2015-02-02 |
2023-08-13 |
mouse |