| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giulia Coarelli, Thomas Wirth, Christine Tranchant, Michel Koenig, Alexandra Durr, Mathieu Anhei. The inherited cerebellar ataxias: an update. Journal of neurology. 2022-09-24. PMID:36152050. |
the inherited cerebellar ataxias: an update. |
2022-09-24 |
2023-08-14 |
Not clear |
| Giulia Coarelli, Thomas Wirth, Christine Tranchant, Michel Koenig, Alexandra Durr, Mathieu Anhei. The inherited cerebellar ataxias: an update. Journal of neurology. 2022-09-24. PMID:36152050. |
this narrative review aims at providing an update on the management of inherited cerebellar ataxias (icas), describing main clinical entities, genetic analysis strategies and recent therapeutic developments. |
2022-09-24 |
2023-08-14 |
Not clear |
| Giulia Coarelli, Thomas Wirth, Christine Tranchant, Michel Koenig, Alexandra Durr, Mathieu Anhei. The inherited cerebellar ataxias: an update. Journal of neurology. 2022-09-24. PMID:36152050. |
to guide diagnosis, several algorithms and a new genetic nomenclature for recessive cerebellar ataxias have been proposed. |
2022-09-24 |
2023-08-14 |
Not clear |
| Marios Hadjivassiliou, Mario Manto, Hiroshi Mitom. Rare Etiologies in Immune-Mediated Cerebellar Ataxias: Diagnostic Challenges. Brain sciences. vol 12. issue 9. 2022-09-23. PMID:36138901. |
rare etiologies in immune-mediated cerebellar ataxias: diagnostic challenges. |
2022-09-23 |
2023-08-14 |
Not clear |
| Marios Hadjivassiliou, Mario Manto, Hiroshi Mitom. Rare Etiologies in Immune-Mediated Cerebellar Ataxias: Diagnostic Challenges. Brain sciences. vol 12. issue 9. 2022-09-23. PMID:36138901. |
immune-mediated cerebellar ataxias (imcas) have diverse etiologies, such as gluten ataxia (ga), post-infectious cerebellitis (pic), miller fisher syndrome (mfs), paraneoplastic cerebellar degeneration (pcd), opsoclonus myoclonus syndrome (oms), and anti-gad ataxia. |
2022-09-23 |
2023-08-14 |
Not clear |
| Lazaros C Triarhou, Mario Mant. The Discovery of the Monoaminergic Innervation of the Cerebellum: Convergence of Divergent and Point-to-Point Systems. Cerebellum (London, England). 2022-09-23. PMID:36149526. |
the discovery of noradrenergic and serotoninergic innervation of the cerebellum has been a crucial step in understanding the neurochemical relationships between brainstem nuclei and the cerebellum, and the attempts to treat cerebellar ataxias pharmacologically. |
2022-09-23 |
2023-08-14 |
Not clear |
| Hoda Ranjbar, Monavareh Soti, Kristi A Kohlmeier, Vahid Sheibani, Meysam Ahmadi-Zeidabadi, Kiana Rafiepour, Mohammad Shaban. The cannabinoid antagonist, AM251 attenuates Ataxia related deficiencies in a cerebellar ataxic model. The International journal of neuroscience. 2022-09-19. PMID:36120979. |
the cannabinoid antagonist, am251 attenuates ataxia related deficiencies in a cerebellar ataxic model. |
2022-09-19 |
2023-08-14 |
Not clear |
| Takehiro Takahashi, Milan Stoiljkovic, Eric Song, Xiao-Bing Gao, Yuki Yasumoto, Eriko Kudo, Fernando Carvalho, Yong Kong, Annsea Park, Marya Shanabrough, Klara Szigeti-Buck, Zhong-Wu Liu, Ashley Kristant, Yalan Zhang, Parker Sulkowski, Peter M Glazer, Leonard K Kaczmarek, Tamas L Horvath, Akiko Iwasak. LINE-1 activation in the cerebellum drives ataxia. Neuron. 2022-09-07. PMID:36070749. |
line-1 activation in the cerebellum drives ataxia. |
2022-09-07 |
2023-08-14 |
mouse |
| Takehiro Takahashi, Milan Stoiljkovic, Eric Song, Xiao-Bing Gao, Yuki Yasumoto, Eriko Kudo, Fernando Carvalho, Yong Kong, Annsea Park, Marya Shanabrough, Klara Szigeti-Buck, Zhong-Wu Liu, Ashley Kristant, Yalan Zhang, Parker Sulkowski, Peter M Glazer, Leonard K Kaczmarek, Tamas L Horvath, Akiko Iwasak. LINE-1 activation in the cerebellum drives ataxia. Neuron. 2022-09-07. PMID:36070749. |
we demonstrated that l1 activation in the cerebellum led to purkinje cell dysfunctions and degeneration and was sufficient to cause ataxia. |
2022-09-07 |
2023-08-14 |
mouse |
| Pallavi Asthana, Gajendra Kumar, Lukasz M Milanowski, Ngan Pan Bennett Au, Siu Chung Chan, Jianpan Huang, Hemin Feng, Kin Ming Kwan, Jufang He, Kannie Wai Yan Chan, Zbigniew K Wszolek, Chi Him Eddie M. Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression. NPJ Regenerative medicine. vol 7. issue 1. 2022-09-06. PMID:36064798. |
here, we demonstrated disrupted cerebellar circuitry and poor motor recovery in ataxia mice after pni. |
2022-09-06 |
2023-08-14 |
mouse |
| Pallavi Asthana, Gajendra Kumar, Lukasz M Milanowski, Ngan Pan Bennett Au, Siu Chung Chan, Jianpan Huang, Hemin Feng, Kin Ming Kwan, Jufang He, Kannie Wai Yan Chan, Zbigniew K Wszolek, Chi Him Eddie M. Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression. NPJ Regenerative medicine. vol 7. issue 1. 2022-09-06. PMID:36064798. |
by restoring cerebellar circuitry through dcn stimulation, and reversal of neurotransmitter imbalance using baclofen, ataxia mice achieve full motor recovery after pni. |
2022-09-06 |
2023-08-14 |
mouse |
| Albert Stezin, Pramod Kumar Pa. Treatable Ataxias: How to Find the Needle in the Haystack? Journal of movement disorders. 2022-09-06. PMID:36065614. |
treatable ataxias with immune-mediated etiologies include gluten ataxia, anti-glutamic acid decarboxylase antibody-associated ataxia, steroid-responsive encephalopathy associated with autoimmune thyroiditis, miller-fisher syndrome, multiple sclerosis, and paraneoplastic cerebellar degeneration. |
2022-09-06 |
2023-08-14 |
Not clear |
| Albert Stezin, Pramod Kumar Pa. Treatable Ataxias: How to Find the Needle in the Haystack? Journal of movement disorders. 2022-09-06. PMID:36065614. |
infective and parainfectious causes of cerebellar ataxias include acute cerebellitis, postinfectious ataxia, whipple's disease, meningoencephalitis, and progressive multifocal leukoencephalopathy. |
2022-09-06 |
2023-08-14 |
Not clear |
| Akira Takekoshi, Akio Kimura, Nobuaki Yoshikura, Isamu Yamakawa, Makoto Urushitani, Katsuya Nakamura, Kunihiro Yoshida, Takayoshi Shimohat. Clinical Features and Neuroimaging Findings of Neuropil Antibody-Positive Idiopathic Sporadic Ataxia of Unknown Etiology. Cerebellum (London, England). 2022-09-03. PMID:36057079. |
using tissue-based immunofluorescence assays (tbas), we examined antibodies against the cerebellum in serum samples from 67 patients who met the isa diagnostic criteria, including 30 patients with multiple system atrophy with predominant cerebellar features (msa-c) and 20 patients with hereditary ataxia (ha), and 18 healthy control subjects. |
2022-09-03 |
2023-08-14 |
human |
| Gengyin Guo, Jianfeng Zhuang, Keke Zhang, Zhizhen Zhou, Yanjun Wang, Zhen Zhan. Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System in Children: Case Reports and Literature Review. Frontiers in surgery. vol 9. 2022-08-29. PMID:36034392. |
symptoms at presentation included increased intracranial pressure and cerebellar symptoms such as headache, altered gait, and ataxia. |
2022-08-29 |
2023-08-14 |
Not clear |
| Yusra Mansour, Alyson Burchell, Randy Kulesz. Abnormal vestibular brainstem structure and function in an animal model of autism spectrum disorder. Brain research. 2022-08-19. PMID:35985362. |
we have recently shown that animals exposed to vpa in utero have fewer neurons in their auditory brainstem, reduced axonal projections to the auditory midbrain and thalamus, reduced expression of the calcium binding protein calbindin (cb) in the brainstem and cerebellum, smaller and occasionally ectopic cerebellar purkinje cells and ataxia on several motor tasks. |
2022-08-19 |
2023-08-14 |
human |
| Kimberly Luttik, Leon Tejwani, Hyoungseok Ju, Terri Driessen, Cleo J L M Smeets, Chandrakanth Reddy Edamakanti, Aryaan Khan, Joy Yun, Puneet Opal, Janghoo Li. Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 34. 2022-08-15. PMID:35969780. |
spinocerebellar ataxia type 1 (sca1) is a dominantly inherited neurodegenerative disease characterized by progressive ataxia and degeneration of specific neuronal populations, including purkinje cells (pcs) in the cerebellum. |
2022-08-15 |
2023-08-14 |
mouse |
| Jeremy D Schmahman. Ferdinando Rossi Lecture: the Cerebellar Cognitive Affective Syndrome-Implications and Future Directions. Cerebellum (London, England). 2022-08-10. PMID:35948744. |
it opened new avenues of investigation into higher order deficits that accompany the ataxias and other cerebellar diseases, as well as the contribution of cerebellar dysfunction to neuropsychiatric and neurocognitive disorders. |
2022-08-10 |
2023-08-14 |
Not clear |
| Jeremy D Schmahman. Ferdinando Rossi Lecture: the Cerebellar Cognitive Affective Syndrome-Implications and Future Directions. Cerebellum (London, England). 2022-08-10. PMID:35948744. |
this new appreciation of the cerebellar incorporation into circuits that subserve cognition and emotion enables deeper understanding and improved care of our patients with cerebellar ataxias and novel cerebellar-based approaches to therapy in neuropsychiatry. |
2022-08-10 |
2023-08-14 |
Not clear |
| Vincent Francis, Walaa Alshafie, Rahul Kumar, Martine Girard, Bernard Brais, Peter S McPherso. The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics. The Journal of biological chemistry. 2022-08-06. PMID:35933016. |
autosomal recessive spastic ataxia of charlevoix-saguenay (arsacs) is a fatal brain disorder featuring cerebellar neurodegeneration leading to spasticity and ataxia. |
2022-08-06 |
2023-08-14 |
Not clear |