| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dean Kirson, Sophia Khom, Larry Rodriguez, Sarah A Wolfe, Florence P Varodayan, Pauravi J Gandhi, Reesha R Patel, Roman Vlkolinsky, Michal Bajo, Marisa Robert. Sex Differences in Acute Alcohol Sensitivity of Naïve and Alcohol Dependent Central Amygdala GABA Synapses. Alcohol and alcoholism (Oxford, Oxfordshire). vol 56. issue 5. 2021-09-15. PMID:33912894. |
in alcohol dependence animal models of aud, the central amygdala (cea) functions as a hub of stress and anxiety processing and gamma-aminobutyric acid (gaba)ergic signaling within the cea is involved in dependence-induced increases in alcohol consumption. |
2021-09-15 |
2023-08-13 |
Not clear |
| Ting Sun, Li Luo, Qin-Qin Tian, Wen-Ju Wang, Qing-Qing Liu, Le Yang, Kun Zhang, Wei Zhang, Ming-Gao Zhao, Qi Yan. Anxiolytic Effects of 8-O-Acetyl Shanzhiside Methylester on Acute and Chronic Anxiety via Inflammatory Response Inhibition and Excitatory/Inhibitory Transmission Imbalance. Neurotoxicity research. vol 38. issue 4. 2021-08-20. PMID:32367473. |
moreover, a reduction in gaba receptors disrupted the excitatory/inhibitory (e/i) balance in the basolateral amygdala (bla), indicated by increased excitatory and decreased inhibitory presynaptic release. |
2021-08-20 |
2023-08-13 |
mouse |
| Khadijeh Alsadat Sharifi, Ameneh Rezayof, Sakineh Alijanpour, Mohammad-Reza Zarrindas. GABA-cannabinoid interplays in the dorsal hippocampus and basolateral amygdala mediate morphine-induced amnesia. Brain research bulletin. vol 157. 2021-08-17. PMID:31981675. |
the aim of the current study was to investigate the involvement of gaba neurotransmission in the ca1 region and endocannabinoid system in the basolateral amygdala (bla) on morphine-induced memory impairment. |
2021-08-17 |
2023-08-13 |
rat |
| Reesha R Patel, Sarah A Wolfe, Michal Bajo, Shawn Abeynaike, Amanda Pahng, Vittoria Borgonetti, Shannon D'Ambrosio, Rana Nikzad, Scott Edwards, Silke Paust, Amanda J Roberts, Marisa Robert. IL-10 normalizes aberrant amygdala GABA transmission and reverses anxiety-like behavior and dependence-induced escalation of alcohol intake. Progress in neurobiology. vol 199. 2021-07-28. PMID:33197496. |
il-10 normalizes aberrant amygdala gaba transmission and reverses anxiety-like behavior and dependence-induced escalation of alcohol intake. |
2021-07-28 |
2023-08-13 |
mouse |
| Reesha R Patel, Sarah A Wolfe, Michal Bajo, Shawn Abeynaike, Amanda Pahng, Vittoria Borgonetti, Shannon D'Ambrosio, Rana Nikzad, Scott Edwards, Silke Paust, Amanda J Roberts, Marisa Robert. IL-10 normalizes aberrant amygdala GABA transmission and reverses anxiety-like behavior and dependence-induced escalation of alcohol intake. Progress in neurobiology. vol 199. 2021-07-28. PMID:33197496. |
mechanistically, amygdala il-10 signaling through pi3k and p38 mapk modulates gaba transmission directly at presynaptic terminals and indirectly through alterations in spontaneous firing. |
2021-07-28 |
2023-08-13 |
mouse |
| Reesha R Patel, Sarah A Wolfe, Michal Bajo, Shawn Abeynaike, Amanda Pahng, Vittoria Borgonetti, Shannon D'Ambrosio, Rana Nikzad, Scott Edwards, Silke Paust, Amanda J Roberts, Marisa Robert. IL-10 normalizes aberrant amygdala GABA transmission and reverses anxiety-like behavior and dependence-induced escalation of alcohol intake. Progress in neurobiology. vol 199. 2021-07-28. PMID:33197496. |
alcohol dependence-induces neuroadaptations in il-10 signaling leading to an overall il-10-induced decrease in gaba transmission, which normalizes dependence-induced elevated amygdala gaba transmission. |
2021-07-28 |
2023-08-13 |
mouse |
| Shisui Fujita, Satomi Yoshida, Tohru Matsuki, Manoj Kumar Jaiswal, Kenjiro Sek. The α1-adrenergic receptors in the amygdala regulate the induction of learned despair through protein kinase C-beta signaling. Behavioural pharmacology. vol 32. issue 1. 2021-06-21. PMID:33164996. |
immunostaining experiments revealed that ~61-75% of α1a-adrenoreceptor-positive neurons were colocalized with gad65/67 in amygdala, implying that the α1-adrenoceptors in amygdala may enormously regulate the gaba release. |
2021-06-21 |
2023-08-13 |
mouse |
| M E Chávez-Pichardo, D Y Reyes-Bravo, M S Mendoza-Trejo, A G Marín-López, M Giordano, N Hernández-Chan, K Domínguez-Marchan, L C Ortega-Rosales, V M Rodrígue. Brain alterations in GABA, glutamate and glutamine markers after chronic atrazine exposure in the male albino rat. Archives of toxicology. vol 94. issue 9. 2021-06-16. PMID:32561961. |
gaba, glutamate, and glutamine levels were differentially altered in brain regions related to nigrostriatal and mesolimbic systems, the amygdala, and the prefrontal cortex. |
2021-06-16 |
2023-08-13 |
rat |
| Xiaoli Xing, Juan Fu, Hongbo Wang, Xigeng Zhen. Contributions of prelimbic cortex, dorsal and ventral hippocampus, and basolateral amygdala to fear return induced by elevated platform stress in rats. Brain research. vol 1761. 2021-03-21. PMID:33662338. |
the contributions of the prelimbic cortex (pl), dorsal hippocampus (dh), ventral hippocampus (vh), and basolateral amygdala (bla) were examined by targeted bilateral intracerebral injection of the gaba |
2021-03-21 |
2023-08-13 |
rat |
| Rebecca Hornung, Addison Pritchard, Paul R Kinchington, Phillip R Krame. Comparing Gene Expression in the Parabrachial and Amygdala of Diestrus and Proestrus Female Rats after Orofacial Varicella Zoster Injection. International journal of molecular sciences. vol 21. issue 16. 2021-02-17. PMID:32796585. |
gaba positive cells in the amygdala are influenced by sex steroid metabolites to affect pain, and sex steroids have been shown to alter the expression of genes in the parabrachial, changing neuronal excitability. |
2021-02-17 |
2023-08-13 |
rat |
| Kazutaka Maeda, Ken-Ichi Inoue, Jun Kunimatsu, Masahiko Takada, Okihide Hikosak. Primate Amygdalo-Nigral Pathway for Boosting Oculomotor Action in Motivating Situations. iScience. vol 23. issue 6. 2021-01-10. PMID:32516719. |
to study the underlying neural mechanism, we first inactivated the amygdala locally and temporarily by injecting a gaba agonist. |
2021-01-10 |
2023-08-13 |
Not clear |
| H Scott, T J Phillips, Y Sze, A Alfieri, M F Rogers, V Volpato, C P Case, P J Brunto. Maternal antioxidant treatment prevents the adverse effects of prenatal stress on the offspring's brain and behavior. Neurobiology of stress. vol 13. 2020-12-22. PMID:33344732. |
blocking oxidative stress using an antioxidant prevented the prenatal stress-induced anxiety phenotype in the male offspring, and prevented sex-specific neurobiological changes, specifically a reduction in dendrite lengths in the hippocampus, as well as reductions in the number of parvalbumin-positive neurons and gaba receptor subunits in the hippocampus and basolateral amygdala of the male offspring. |
2020-12-22 |
2023-08-13 |
rat |
| Louis Monti, Michael R Liebowit. Neural circuits of anxiolytic and antidepressant CNS spectrums. 2020-12-11. PMID:33092667. |
we hypothesize that afferent signals triggered by activation of these peripheral receptors could reach subgroups of olfactory bulb neurons broadcasting information to gamma-aminobutyric acid (gabaergic) and corticotropin-releasing hormone (crh) neurons in the limbic amygdala. |
2020-12-11 |
2023-08-13 |
human |
| S Khom, T Steinkellner, T S Hnasko, M Robert. Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala. Science advances. vol 6. issue 12. 2020-11-24. PMID:32206720. |
here, we examined regulation of gaba transmission in the medial subdivision of the central amygdala (cem) by the sp/nk-1r system, and its neuroadaptation following chronic alcohol exposure. |
2020-11-24 |
2023-08-13 |
rat |
| Lindsey M Biggs, Michael Meredit. ActivatIon of Calcium binding protein-ir neurons IN MEDIAL AMYGDALA during chemosignal processing. Chemical senses. 2020-10-12. PMID:32386197. |
medial amygdala projections to basal forebrain contibute to generation of appropriate behavioral responses and gaba neurons are important for these functions, both as interneurons and projection neurons. |
2020-10-12 |
2023-08-13 |
Not clear |
| Lindsey M Biggs, Michael Meredit. ActivatIon of Calcium binding protein-ir neurons IN MEDIAL AMYGDALA during chemosignal processing. Chemical senses. 2020-10-12. PMID:32386197. |
this additional evidence for chemosensory specificity in the response of medial amygdala to social chemical signals, in cells characterized by cbp expression, suggests multiple gaba circuit elements may be involved in information processing for behavioral response. |
2020-10-12 |
2023-08-13 |
Not clear |
| Nina Levar, Judith M C van Leeuwen, Nicolaas A J Puts, Damiaan Denys, Guido A van Winge. GABA Concentrations in the Anterior Cingulate Cortex Are Associated with Fear Network Function and Fear Recovery in Humans. Frontiers in human neuroscience. vol 11. 2020-10-01. PMID:28496404. |
the results showed that high gaba levels were associated with increased scrs, enhanced activation of the right amygdala, and reduced amygdala-ventromedial prefrontal cortex connectivity during fear recovery. |
2020-10-01 |
2023-08-13 |
human |
| Nina Levar, Judith M C van Leeuwen, Nicolaas A J Puts, Damiaan Denys, Guido A van Winge. GABA Concentrations in the Anterior Cingulate Cortex Are Associated with Fear Network Function and Fear Recovery in Humans. Frontiers in human neuroscience. vol 11. 2020-10-01. PMID:28496404. |
follow-up analyses exclusively for the extinction phase showed that high gaba levels were associated with reduced amygdala activation and enhanced amygdala-ventromedial prefrontal cortex connectivity, despite the absence of correlations between gaba and physiological responses. |
2020-10-01 |
2023-08-13 |
human |
| Nina Levar, Judith M C van Leeuwen, Nicolaas A J Puts, Damiaan Denys, Guido A van Winge. GABA Concentrations in the Anterior Cingulate Cortex Are Associated with Fear Network Function and Fear Recovery in Humans. Frontiers in human neuroscience. vol 11. 2020-10-01. PMID:28496404. |
in addition, the opposite effects of gaba on amygdala activity and connectivity during fear extinction compared to fear recovery suggest that dacc gaba may initially facilitate extinction learning. |
2020-10-01 |
2023-08-13 |
human |
| Firoozeh Alavian, Saeedeh Ghiasvand, Hedayat Sahraei, Maryam Rafiei-Ra. Intervention of the Gamma-Aminobutyric Acid Type B Receptors of the Amygdala Central Nucleus on the Sensitivity of the Morphine-Induced Conditionally Preferred Location in Wistar Female Rats. Addiction & health. vol 9. issue 2. 2020-10-01. PMID:29299214. |
intervention of the gamma-aminobutyric acid type b receptors of the amygdala central nucleus on the sensitivity of the morphine-induced conditionally preferred location in wistar female rats. |
2020-10-01 |
2023-08-13 |
rat |