| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carola Eva, Alessandra Oberto, Paolo Mele, Mariangela Serra, Giovanni Biggi. Role of brain neuroactive steroids in the functional interplay between the GABA(A) and the NPY-Y1 receptor mediated signals in the amygdala. Pharmacology, biochemistry, and behavior. vol 84. issue 4. 2006-12-20. PMID:16824587. |
by using a transgenic mouse model carrying the murine y(1)r gene promoter fused to the lacz reporter gene (y(1)r/lacz mice), we showed that prolonged pharmacologically or physiologically induced changes in the cerebrocortical concentrations of the neuroactive steroids 3alpha-hydroxy-5alpha-pregnan- 20-one (3alpha,5alpha th prog) and tetrahydrodeoxycorticosterone (3alpha,5alpha th doc) increases y(1)r/lacz transgene expression in the central and medial amygdala, an effect similar to that induced by long-term treatment with positive modulators of the gaba(a) receptor complex (diazepam or abecarnil). |
2006-12-20 |
2023-08-12 |
mouse |
| Carola Eva, Alessandra Oberto, Paolo Mele, Mariangela Serra, Giovanni Biggi. Role of brain neuroactive steroids in the functional interplay between the GABA(A) and the NPY-Y1 receptor mediated signals in the amygdala. Pharmacology, biochemistry, and behavior. vol 84. issue 4. 2006-12-20. PMID:16824587. |
these data provide evidence that neuroactive steroids may play an important role in the functional interaction between the gaba(a) receptor and npy-y(1)r mediated pathways in the amygdala, which might represent an important regulatory mechanism for modulation of several functions, including ethanol withdrawal. |
2006-12-20 |
2023-08-12 |
mouse |
| Carola Eva, Mariangela Serra, Paolo Mele, GianCarlo Panzica, Alessandra Obert. Physiology and gene regulation of the brain NPY Y1 receptor. Frontiers in neuroendocrinology. vol 27. issue 3. 2006-12-15. PMID:16989896. |
chronic modulation of gaba(a) receptor function by benzodiazepines or neuroactive steroids also affects y(1)r expression in the amygdala, suggesting that a functional interaction between the gaba(a) receptor and y(1)r mediated signalling may contribute to the regulation of emotional behaviour. |
2006-12-15 |
2023-08-12 |
human |
| Aleksei Nelovkov, Tarmo Areda, Jürgen Innos, Sulev Kõks, Eero Vasa. Rats displaying distinct exploratory activity also have different expression patterns of gamma-aminobutyric acid- and cholecystokinin-related genes in brain regions. Brain research. vol 1100. issue 1. 2006-09-18. PMID:16769038. |
limbic system-associated membrane protein (lsamp) gene, gamma-aminobutyric acid-(gaba)- and cholecystokinin-(cck)-related genes were analyzed in the frontal cortex, amygdala and periaqueductal gray (pag) after exposure of rats to exploratory challenge. |
2006-09-18 |
2023-08-12 |
rat |
| Dustin W DuBois, Andreas Perlegas, Donald W Floyd, Jeffery L Weiner, Brian A McCoo. Distinct functional characteristics of the lateral/basolateral amygdala GABAergic system in C57BL/6J and DBA/2J mice. The Journal of pharmacology and experimental therapeutics. vol 318. issue 2. 2006-08-31. PMID:16651400. |
because lateral/basolateral amygdala (bla) gaba(a) receptors help regulate anxiety-like behaviors, we have tested the hypothesis that differences in receptor function/expression may be related to strain-specific differences in experimentally measured anxiety. |
2006-08-31 |
2023-08-12 |
mouse |
| Marisa Roberto, George R Siggin. Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdala. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 25. 2006-08-14. PMID:16788074. |
nociceptin/orphanin fq presynaptically decreases gabaergic transmission and blocks the ethanol-induced increase of gaba release in central amygdala. |
2006-08-14 |
2023-08-12 |
rat |
| Ping Jun Zhu, David M Lovinge. Ethanol potentiates GABAergic synaptic transmission in a postsynaptic neuron/synaptic bouton preparation from basolateral amygdala. Journal of neurophysiology. vol 96. issue 1. 2006-08-04. PMID:16624993. |
in the present study, a mechanically isolated neuron/bouton preparation from the basolateral amygdala was used to examine the effects of ethanol on spontaneous gabaergic synaptic currents elicited by gaba release from the presynaptic terminals. |
2006-08-04 |
2023-08-12 |
Not clear |
| Brian J Young, Christian J Coo. Reduced basal GABA concentrations in the rat amygdala during pregnancy. Physiology & behavior. vol 87. issue 4. 2006-07-26. PMID:16519910. |
reduced basal gaba concentrations in the rat amygdala during pregnancy. |
2006-07-26 |
2023-08-12 |
rat |
| Irit Akirav, Hagit Raizel, Mouna Marou. Enhancement of conditioned fear extinction by infusion of the GABA(A) agonist muscimol into the rat prefrontal cortex and amygdala. The European journal of neuroscience. vol 23. issue 3. 2006-05-09. PMID:16487156. |
enhancement of conditioned fear extinction by infusion of the gaba(a) agonist muscimol into the rat prefrontal cortex and amygdala. |
2006-05-09 |
2023-08-12 |
rat |
| Irit Akirav, Hagit Raizel, Mouna Marou. Enhancement of conditioned fear extinction by infusion of the GABA(A) agonist muscimol into the rat prefrontal cortex and amygdala. The European journal of neuroscience. vol 23. issue 3. 2006-05-09. PMID:16487156. |
the involvement of gaba(a) receptors in fear extinction in the prefrontal cortex and amygdala is of particular interest, because of the role of these areas in emotional processes, and the role of the gaba(a) receptors in anxiety states. |
2006-05-09 |
2023-08-12 |
rat |
| Jeffrey Burgdorf, Jaak Panksep. The neurobiology of positive emotions. Neuroscience and biobehavioral reviews. vol 30. issue 2. 2006-05-05. PMID:16099508. |
dopamine independent mechanisms utilizing opiate and gaba receptors in the ventral striatum, amygdala and orbital frontal cortex are important in elaborating consummatory pa (i.e. |
2006-05-05 |
2023-08-12 |
Not clear |
| M Van Nobelen, L Kokkinidi. Amygdaloid GABA, not glutamate neurotransmission or mRNA transcription controls footshock-associated fear arousal in the acoustic startle paradigm. Neuroscience. vol 137. issue 2. 2006-05-03. PMID:16289581. |
bilateral infusion into the basolateral amygdala of the gaba(a) receptor agonist muscimol in doses ranging from 0.001-0.5 microg reliably blocked the shock sensitization of acoustic startle responding. |
2006-05-03 |
2023-08-12 |
rat |
| M Van Nobelen, L Kokkinidi. Amygdaloid GABA, not glutamate neurotransmission or mRNA transcription controls footshock-associated fear arousal in the acoustic startle paradigm. Neuroscience. vol 137. issue 2. 2006-05-03. PMID:16289581. |
the muscimol results were interpreted to suggest that decreased gaba neurotransmission in the amygdala may be essential for the neural causation of fear that is acquired and expressed by conditioned stimuli. |
2006-05-03 |
2023-08-12 |
rat |
| Jay F Muller, Franco Mascagni, Alexander J McDonal. Pyramidal cells of the rat basolateral amygdala: synaptology and innervation by parvalbumin-immunoreactive interneurons. The Journal of comparative neurology. vol 494. issue 4. 2006-04-04. PMID:16374802. |
the activity of these neurons is tightly controlled by gamma-aminobutyric acid (gaba)-ergic interneurons, especially a parvalbumin-positive (pv(+)) subpopulation that constitutes almost half of all interneurons in the basolateral amygdala. |
2006-04-04 |
2023-08-12 |
rat |
| Laurie L Wellman, Karen Gale, Ludise Malkov. GABAA-mediated inhibition of basolateral amygdala blocks reward devaluation in macaques. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 18. 2006-03-23. PMID:15872105. |
here, we tested the hypothesis that transient inactivation of amygdala by the gaba(a) agonist muscimol (mus), specifically during the period of reward satiation, would have a similar effect. |
2006-03-23 |
2023-08-12 |
monkey |
| Neeta Pillai-Nair, Anitha K Panicker, Ramona M Rodriguiz, Kelly L Gilmore, Galina P Demyanenko, Josh Z Huang, William C Wetsel, Patricia F Manes. Neural cell adhesion molecule-secreting transgenic mice display abnormalities in GABAergic interneurons and alterations in behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 18. 2006-03-23. PMID:15872114. |
ncam-ec transgenic mice exhibited a striking reduction in synaptic puncta of gabaergic interneurons in the cingulate, frontal association cortex, and amygdala but not hippocampus, as shown by decreased immunolabeling of glutamic acid decarboxylase-65 (gad65), gad67, and gaba transporter 1. |
2006-03-23 |
2023-08-12 |
mouse |
| Hans-Christian Pap. GABAergic neurons: gate masters of the amygdala, mastered by dopamine. Neuron. vol 48. issue 6. 2006-02-24. PMID:16364892. |
in this issue of neuron, marowsky and colleagues identify two clusters of paracapsular intercalated gaba neurons in amygdala slice preparations of gad67-gfp mice. |
2006-02-24 |
2023-08-12 |
mouse |
| Hans-Christian Pap. GABAergic neurons: gate masters of the amygdala, mastered by dopamine. Neuron. vol 48. issue 6. 2006-02-24. PMID:16364892. |
these gaba neurons mediate inhibition from cortical afferents to both the major input and output station of the amygdala, are inhibited during action of dopamine via d1 receptors, and are thus likely to represent important cellular players during dopaminergic disinhibition related to increased affective behavior. |
2006-02-24 |
2023-08-12 |
mouse |
| L R Johnson, C Farb, J H Morrison, B S McEwen, J E LeDou. Localization of glucocorticoid receptors at postsynaptic membranes in the lateral amygdala. Neuroscience. vol 136. issue 1. 2006-02-14. PMID:16181741. |
these newly observed glucocorticoid receptor immunoreactive sites were in addition to glucocorticoid receptor immunoreactive signals observed using electron and confocal microscopy in lateral amygdala principal neuron and gaba neuron soma and nuclei, cellular domains traditionally associated with glucocorticoid immunoreactivity. |
2006-02-14 |
2023-08-12 |
rat |
| Brian A Baldo, Karen M Alsene, Alejandro Negron, Ann E Kelle. Hyperphagia induced by GABAA receptor-mediated inhibition of the nucleus accumbens shell: dependence on intact neural output from the central amygdaloid region. Behavioral neuroscience. vol 119. issue 5. 2006-02-14. PMID:16300426. |
to investigate the role of corticolimbic input in modulating feeding-related nucleus accumbens (acb) circuitry, researchers temporarily deactivated sites within the basolateral amygdaloid complex (bla) or central amygdaloid region (cea) via gaba(a) agonist (muscimol) infusions and measured feeding responses following muscimol infusions into the acb shell. |
2006-02-14 |
2023-08-12 |
Not clear |