| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J F Codrington, H W Li, F Kutlar, L H Gu, M Ramachandran, T H Huisma. Observations on the levels of Hb A2 in patients with different beta-thalassemia mutations and a delta chain variant. Blood. vol 76. issue 6. 1990-10-23. PMID:1698102. |
one is consistent with a general mechanism concerning the relative excess of alpha chains in beta chain deficiencies which will combine with delta chains to form variable levels of hb a2 dependent on the severity of the beta chain deficiency. |
1990-10-23 |
2023-08-11 |
human |
| B D Shivers, I Killisch, R Sprengel, H Sontheimer, M Köhler, P R Schofield, P H Seebur. Two novel GABAA receptor subunits exist in distinct neuronal subpopulations. Neuron. vol 3. issue 3. 1990-10-22. PMID:2561970. |
these subunits, gamma 2 and delta, share approximately 35% sequence identity with alpha and beta subunits and form functional gaba-gated chloride channels when expressed alone in vitro. |
1990-10-22 |
2023-08-11 |
human |
| P Blount, J P Merli. Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor. Neuron. vol 3. issue 3. 1990-10-22. PMID:2642001. |
the gamma and delta, but not the beta, subunits associated efficiently with the alpha subunit, and they extensively modified its binding characteristics. |
1990-10-22 |
2023-08-11 |
mouse |
| P Blount, J P Merli. Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor. Neuron. vol 3. issue 3. 1990-10-22. PMID:2642001. |
the alpha gamma and alpha delta complexes formed distinctly different high affinity binding sites for the competitive antagonist d-tubocurarine that, together, completely accounted for the two nonequivalent antagonist binding sites in native achr. |
1990-10-22 |
2023-08-11 |
mouse |
| P Blount, J P Merli. Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor. Neuron. vol 3. issue 3. 1990-10-22. PMID:2642001. |
the alpha delta complex and native achr had similar affinities for the agonist carbamylcholine. |
1990-10-22 |
2023-08-11 |
mouse |
| P Blount, J P Merli. Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor. Neuron. vol 3. issue 3. 1990-10-22. PMID:2642001. |
in contrast, although the alpha gamma complex contains the higher affinity competitive antagonist binding site, it had an affinity for carbamylcholine that was an order of magnitude less than that of the alpha delta complex or the achr. |
1990-10-22 |
2023-08-11 |
mouse |
| P Blount, J P Merli. Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor. Neuron. vol 3. issue 3. 1990-10-22. PMID:2642001. |
these data support a model of two nonequivalent binding sites within the achr and imply that the basis for this nonequivalence is the association of the alpha subunit with the gamma or delta subunit. |
1990-10-22 |
2023-08-11 |
mouse |
| M Isobe, N Sadamori, G Russo, S Shimizu, S Yamamori, T Itoyama, Y Yamada, S Ikeda, M Ichimaru, J Kaga. Rearrangements in the human T-cell-receptor alpha-chain locus in patients with adult T-cell leukemia carrying translocations involving chromosome 14q11. Cancer research. vol 50. issue 19. 1990-10-19. PMID:2169336. |
for this purpose we have generated an extensive series of probes to define the specificity and the diversity of rearrangement occurring at the widely spanned j alpha-c alpha locus and the complex d delta-j delta-c delta-v delta 2 locus. |
1990-10-19 |
2023-08-11 |
human |
| J L Klein, A Selvakumar, J A Trapani, B Dupon. Characterization of a novel, human cytotoxic lymphocyte-specific serine protease cDNA clone (CSP-C). Tissue antigens. vol 35. issue 5. 1990-10-19. PMID:2402757. |
it has recently been reported that human chromosome 14q11, in addition to containing the genes encoding cytotoxic serine protease b (csp-b), cathepsin g, and the t-cell receptor alpha and delta genes, also includes an additional genomic dna clone which cross-hybridized with csp-b and cathepsin g, cathepsin-like gene-2 (cgl-2). |
1990-10-19 |
2023-08-11 |
mouse |
| P Huang, S Chubb, W Plunket. Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine. A mechanism for cytotoxicity. The Journal of biological chemistry. vol 265. issue 27. 1990-10-18. PMID:1697861. |
human dna polymerase alpha incorporated more f-ara-amp into dna than polymerase epsilon (proliferating cell nuclear antigen-independent dna polymerase delta) and was more sensitive to inhibition by f-ara-atp. |
1990-10-18 |
2023-08-11 |
human |
| P Gaulard, P Bourquelot, P Kanavaros, C Haioun, J P Le Couedic, M Divine, M Goossens, E S Zafrani, J P Farcet, F Reye. Expression of the alpha/beta and gamma/delta T-cell receptors in 57 cases of peripheral T-cell lymphomas. Identification of a subset of gamma/delta T-cell lymphomas. The American journal of pathology. vol 137. issue 3. 1990-10-12. PMID:1698028. |
a third pattern (cd3 +/- beta f1-tcr delta-1-) was seen in 12 cases (21%), in which, by contrast to normal post-thymic t cells, no evidence of either alpha beta or gamma delta t cell receptor was found. |
1990-10-12 |
2023-08-11 |
Not clear |
| M Goulian, C J Hear. An inhibitor of DNA polymerases alpha and delta in calf thymus DNA. Nucleic acids research. vol 18. issue 16. 1990-10-11. PMID:2118625. |
an inhibitor of dna polymerases alpha and delta in calf thymus dna. |
1990-10-11 |
2023-08-11 |
Not clear |
| M Goulian, C J Hear. An inhibitor of DNA polymerases alpha and delta in calf thymus DNA. Nucleic acids research. vol 18. issue 16. 1990-10-11. PMID:2118625. |
both dna polymerases alpha and delta are extremely sensitive whereas, dna polymerases beta and gamma are resistant. |
1990-10-11 |
2023-08-11 |
Not clear |
| M Goulian, C J Hear. An inhibitor of DNA polymerases alpha and delta in calf thymus DNA. Nucleic acids research. vol 18. issue 16. 1990-10-11. PMID:2118625. |
the last result also suggests the use of heparin as a specific inhibitor of purified mammalian dna polymerases alpha and delta, similar to the use of aphidicolin. |
1990-10-11 |
2023-08-11 |
Not clear |
| C L Ives, K F Bot. Characterization of chromosomal DNA amplifications with associated tetracycline resistance in Bacillus subtilis. Journal of bacteriology. vol 172. issue 9. 1990-10-09. PMID:1697573. |
the amplified dna also showed homology (through hybridization analysis) with pam alpha 1 delta 1, a gram-positive tcr plasmid, indicating that b. subtilis normally contains a silent integrated copy of the gene whose amplification confers tcr. |
1990-10-09 |
2023-08-11 |
Not clear |
| E Braakman, P S Goedegebuure, R J Vreugdenhil, D M Segal, S Shaw, R L Bolhui. ICAM- melanoma cells are relatively resistant to CD3-mediated T-cell lysis. International journal of cancer. vol 46. issue 3. 1990-10-09. PMID:1975566. |
the icam-1- melanoma-derived cell line igr39 was relatively resistant to cd3-mediated lysis by both tcr alpha beta + and tcr gamma delta + ctl, when compared with icam-1+ cell lines. |
1990-10-09 |
2023-08-11 |
Not clear |
| K S De Jongh, C Warner, W A Catteral. Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene. The Journal of biological chemistry. vol 265. issue 25. 1990-10-09. PMID:2168391. |
alpha 2 and delta are encoded by the same gene. |
1990-10-09 |
2023-08-11 |
rabbit |
| K S De Jongh, C Warner, W A Catteral. Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene. The Journal of biological chemistry. vol 265. issue 25. 1990-10-09. PMID:2168391. |
polyacrylamide gel electrophoresis of purified rabbit skeletal muscle l-type calcium channel before and after reduction of disulfide bonds confirmed that 27- and 24-kda forms of the delta subunit are disulfide-linked to the 143-kda alpha 2 subunit. |
1990-10-09 |
2023-08-11 |
rabbit |
| K S De Jongh, C Warner, W A Catteral. Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene. The Journal of biological chemistry. vol 265. issue 25. 1990-10-09. PMID:2168391. |
the amino acid sequences of three peptides obtained by tryptic digestion of the delta subunits corresponded to amino acid sequences predicted from the 3' region of the mrna encoding alpha 2. |
1990-10-09 |
2023-08-11 |
rabbit |
| K S De Jongh, C Warner, W A Catteral. Subunits of purified calcium channels. Alpha 2 and delta are encoded by the same gene. The Journal of biological chemistry. vol 265. issue 25. 1990-10-09. PMID:2168391. |
one of these peptides had the same sequence as the n terminus of the 24- and 27-kda forms of the delta subunit and corresponded to residues 935-946 of the predicted alpha 2 primary sequence. |
1990-10-09 |
2023-08-11 |
rabbit |