| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Lin, G Matsuzaki, H Kenai, K Nomot. Progenies of fetal thymocytes are the major source of CD4-CD8+ alpha alpha intestinal intraepithelial lymphocytes early in ontogeny. European journal of immunology. vol 24. issue 8. 1994-09-09. PMID:8056037. |
the thymus dependency of tcr gamma delta iel and tcr alpha beta cd4-cd8+ iel was less prominent in older mice (7- to 10-week-old mice), as the total number of these iel increased in ntx mice, but still remained severalfold less than that in euthymic mice. |
1994-09-09 |
2023-08-12 |
mouse |
| T Lin, G Matsuzaki, H Kenai, K Nomot. Progenies of fetal thymocytes are the major source of CD4-CD8+ alpha alpha intestinal intraepithelial lymphocytes early in ontogeny. European journal of immunology. vol 24. issue 8. 1994-09-09. PMID:8056037. |
furthermore, we demonstrate, by grafting the fetal thymus of cbf1 (h-2b/d) mice under the kidney capsule of congenitally nude athymic mice of balb/c background (h-2d), that a substantial number of tcr gamma delta iel and tcr alpha beta cd4-cd8+ alpha alpha iel can be thymically derived (h-2b+). |
1994-09-09 |
2023-08-12 |
mouse |
| T Lin, G Matsuzaki, H Kenai, K Nomot. Progenies of fetal thymocytes are the major source of CD4-CD8+ alpha alpha intestinal intraepithelial lymphocytes early in ontogeny. European journal of immunology. vol 24. issue 8. 1994-09-09. PMID:8056037. |
in contrast, but consistent with our ntx data, grafting of adult thymi into nude mice generated virtually no tcr gamma delta iel and relatively less tcr alpha beta cd4-cd8+ alpha alpha iel than did the grafting of fetal thymi. |
1994-09-09 |
2023-08-12 |
mouse |
| T Lin, G Matsuzaki, H Kenai, K Nomot. Progenies of fetal thymocytes are the major source of CD4-CD8+ alpha alpha intestinal intraepithelial lymphocytes early in ontogeny. European journal of immunology. vol 24. issue 8. 1994-09-09. PMID:8056037. |
these results suggest that the thymus is the major source of tcr gamma delta and tcr alpha beta cd4-cd8+ alpha alpha iel early in ontogeny, but that the extrathymic pathway is probably the major source of these iel later in ontogeny. |
1994-09-09 |
2023-08-12 |
mouse |
| T Lin, G Matsuzaki, H Kenai, K Kishihara, S Nabeshima, W P Fung-Leung, T W Mak, K Nomot. Characteristics of fetal thymus-derived T cell receptor gamma delta intestinal intraepithelial lymphocytes. European journal of immunology. vol 24. issue 8. 1994-09-09. PMID:8056038. |
phenotypically, ftg-derived tcr gamma delta iel were similar to their extrathymically derived counterparts in that most were thy-1-, cd5- and cd8 alpha alpha (homodimer). |
1994-09-09 |
2023-08-12 |
mouse |
| T Lin, G Matsuzaki, H Kenai, K Kishihara, S Nabeshima, W P Fung-Leung, T W Mak, K Nomot. Characteristics of fetal thymus-derived T cell receptor gamma delta intestinal intraepithelial lymphocytes. European journal of immunology. vol 24. issue 8. 1994-09-09. PMID:8056038. |
this later finding suggests that the cd8 alpha alpha molecule develops extrathymically for ftg-derived cd8 alpha alpha tcr gamma delta iel. |
1994-09-09 |
2023-08-12 |
mouse |
| J A Bibb, G Bernhardt, E Wimme. The human poliovirus receptor alpha is a serine phosphoprotein. Journal of virology. vol 68. issue 9. 1994-09-09. PMID:8057492. |
whereas the two membrane-bound isoforms, hpvr alpha and hpvr delta, share identical three-domain extracellular portions, their c-terminal cytoplasmic parts differ considerably. |
1994-09-09 |
2023-08-12 |
human |
| J A Bibb, G Bernhardt, E Wimme. The human poliovirus receptor alpha is a serine phosphoprotein. Journal of virology. vol 68. issue 9. 1994-09-09. PMID:8057492. |
this feature is well conserved in the corresponding monkey proteins agm alpha 1, agm delta 1, and agm alpha 2. |
1994-09-09 |
2023-08-12 |
human |
| J A Bibb, G Bernhardt, E Wimme. The human poliovirus receptor alpha is a serine phosphoprotein. Journal of virology. vol 68. issue 9. 1994-09-09. PMID:8057492. |
in this short communication we report that hpvr alpha and possibly also agm alpha 1 and agm alpha 2, but not the delta isoforms, are phosphoproteins. |
1994-09-09 |
2023-08-12 |
human |
| M T Norcum, D A Wilkinson, M C Carlson, J F Hainfeld, G M Carlso. Structure of phosphorylase kinase. A three-dimensional model derived from stained and unstained electron micrographs. Journal of molecular biology. vol 241. issue 1. 1994-09-08. PMID:8051711. |
this study describes four characteristic views of the hexadecameric holoenzyme (alpha 4 beta 4 gamma 4 delta 4) as observed in both negatively stained and unstained electron micrographs. |
1994-09-08 |
2023-08-12 |
Not clear |
| D Mitropoulos, S Kooi, J Rodriguez-Villanueva, C D Platsouca. Characterization of fresh (uncultured) tumour-infiltrating lymphocytes (TIL) and TIL-derived T cell lines from patients with renal cell carcinoma. Clinical and experimental immunology. vol 97. issue 2. 1994-09-06. PMID:8050183. |
these fresh til comprised cd3+ (20-84%); cd4+ (3-15%); cd8+ (13-35%); alpha beta tcr+ (20-50%); gamma delta tcr+ (3-17%); cd16+ (1-18%) and cd56+ (3-10%) cells. |
1994-09-06 |
2023-08-12 |
Not clear |
| D Mitropoulos, S Kooi, J Rodriguez-Villanueva, C D Platsouca. Characterization of fresh (uncultured) tumour-infiltrating lymphocytes (TIL) and TIL-derived T cell lines from patients with renal cell carcinoma. Clinical and experimental immunology. vol 97. issue 2. 1994-09-06. PMID:8050183. |
these t cell lines consisted primarily of cd3+ (51-94%); cd4+ (1-80%); cd8+ (0-84%); alpha beta tcr+ (65-87%); gamma delta tcr+ (0-25%); cd16+ (0-16%) and cd56+ (2-57%) cells. |
1994-09-06 |
2023-08-12 |
Not clear |
| G B Smith, R W Olse. Identification of a [3H]muscimol photoaffinity substrate in the bovine gamma-aminobutyric acidA receptor alpha subunit. The Journal of biological chemistry. vol 269. issue 32. 1994-09-06. PMID:8051133. |
the residue carrying the label, phe65 on alpha 1, is conserved among all gabaa receptor alpha subunits, gamma 2, and delta. |
1994-09-06 |
2023-08-12 |
rat |
| M Nanno, S Matsumoto, R Koike, M Miyasaka, M Kawaguchi, T Masuda, S Miyawaki, Z Cai, T Shimamura, Y Fujiur. Development of intestinal intraepithelial T lymphocytes is independent of Peyer's patches and lymph nodes in aly mutant mice. Journal of immunology (Baltimore, Md. : 1950). vol 153. issue 5. 1994-09-06. PMID:8051406. |
although the population size of major cd8 alpha alpha+ and cd4-, cd8- iel-gamma delta subsets is slightly reduced, the use of tcr-gamma- and -delta-chain variable gene segments by iel-gamma delta remains almost the same in aly/aly mice. |
1994-09-06 |
2023-08-12 |
mouse |
| K Hara, K Yonezawa, H Sakaue, A Ando, K Kotani, T Kitamura, Y Kitamura, H Ueda, L Stephens, T R Jackso. 1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 16. 1994-09-02. PMID:8052599. |
in this study, the stable overexpression in a chinese hamster ovary (cho) cell line of a mutant p85 alpha (delta p85) protein, which lacks a binding site for p110, disrupted the complex formation between irs-1 and the catalytic subunit of pi 3-kinase in intact cells during insulin stimulation. |
1994-09-02 |
2023-08-12 |
Not clear |
| C M Simbulan, K Tamiya-Koizumi, M Suzuki, M Shoji, T Taki, S Yoshid. Sphingosine inhibits the synthesis of RNA primers by primase in vitro. Biochemistry. vol 33. issue 30. 1994-09-01. PMID:7519054. |
sphingosine had no effect on dna polymerases alpha and beta and slightly inhibited dna polymerases gamma, delta, and epsilon. |
1994-09-01 |
2023-08-12 |
Not clear |
| C Giachino, M P Rocci, M Bottaro, G Matullo, G De Libero, N Migon. T cell receptor V delta 2-C alpha transcripts are present in the thymus but virtually absent in the periphery. Journal of immunology (Baltimore, Md. : 1950). vol 153. issue 4. 1994-09-01. PMID:8046236. |
t cell receptor v delta 2-c alpha transcripts are present in the thymus but virtually absent in the periphery. |
1994-09-01 |
2023-08-12 |
Not clear |
| C Giachino, M P Rocci, M Bottaro, G Matullo, G De Libero, N Migon. T cell receptor V delta 2-C alpha transcripts are present in the thymus but virtually absent in the periphery. Journal of immunology (Baltimore, Md. : 1950). vol 153. issue 4. 1994-09-01. PMID:8046236. |
to investigate whether the v delta 2-(d)-j alpha gene configuration, characteristically associated with the major subset of acute lymphoblastic leukemias in humans, might have a physiologic role in t cell ontogeny, we have looked for v delta 2-c alpha transcripts in the thymus and peripheral blood of normal donors. |
1994-09-01 |
2023-08-12 |
Not clear |
| C Giachino, M P Rocci, M Bottaro, G Matullo, G De Libero, N Migon. T cell receptor V delta 2-C alpha transcripts are present in the thymus but virtually absent in the periphery. Journal of immunology (Baltimore, Md. : 1950). vol 153. issue 4. 1994-09-01. PMID:8046236. |
interestingly, over 80% of 43 v delta 2-c alpha cdnas randomly isolated from one postnatal thymus appeared to maintain an open reading frame. |
1994-09-01 |
2023-08-12 |
Not clear |
| C Giachino, M P Rocci, M Bottaro, G Matullo, G De Libero, N Migon. T cell receptor V delta 2-C alpha transcripts are present in the thymus but virtually absent in the periphery. Journal of immunology (Baltimore, Md. : 1950). vol 153. issue 4. 1994-09-01. PMID:8046236. |
this suggests that in the thymus the v delta 2-c alpha products might be exposed to selective pressure. |
1994-09-01 |
2023-08-12 |
Not clear |