| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M H Akabas, A Karli. Identification of acetylcholine receptor channel-lining residues in the M1 segment of the alpha-subunit. Biochemistry. vol 34. issue 39. 1995-11-08. PMID:7547996. |
we mutated each of the other 14 residues to cysteine and expressed the mutant alpha subunits, together with wild-type beta, gamma, and delta subunits, in xenopus oocytes. |
1995-11-08 |
2023-08-12 |
xenopus_laevis |
| M De Waard, K P Campbel. Subunit regulation of the neuronal alpha 1A Ca2+ channel expressed in Xenopus oocytes. The Journal of physiology. vol 485 ( Pt 3). 1995-11-07. PMID:7562605. |
voltage-dependent ca2+ channels are multi-protein complexes composed of at least three subunits: alpha 1, alpha 2 delta and beta. |
1995-11-07 |
2023-08-12 |
xenopus_laevis |
| M De Waard, K P Campbel. Subunit regulation of the neuronal alpha 1A Ca2+ channel expressed in Xenopus oocytes. The Journal of physiology. vol 485 ( Pt 3). 1995-11-07. PMID:7562605. |
various subunit combinations were studied: alpha 1a, alpha 1a alpha 2 delta b, alpha 1a beta or alpha 1a alpha 2 delta b beta. |
1995-11-07 |
2023-08-12 |
xenopus_laevis |
| M De Waard, K P Campbel. Subunit regulation of the neuronal alpha 1A Ca2+ channel expressed in Xenopus oocytes. The Journal of physiology. vol 485 ( Pt 3). 1995-11-07. PMID:7562605. |
both ancillary subunits alpha 2 delta and beta induced considerable changes in the biophysical properties of the alpha 1a current. |
1995-11-07 |
2023-08-12 |
xenopus_laevis |
| M De Waard, K P Campbel. Subunit regulation of the neuronal alpha 1A Ca2+ channel expressed in Xenopus oocytes. The Journal of physiology. vol 485 ( Pt 3). 1995-11-07. PMID:7562605. |
the alpha 2 delta b subunit does not modify the properties of alpha 1a ca2+ channels in the absence of beta subunits. |
1995-11-07 |
2023-08-12 |
xenopus_laevis |
| M De Waard, K P Campbel. Subunit regulation of the neuronal alpha 1A Ca2+ channel expressed in Xenopus oocytes. The Journal of physiology. vol 485 ( Pt 3). 1995-11-07. PMID:7562605. |
both alpha 2 delta b and beta 1 b subunits slightly modified the sensitivity of the alpha 1a subunit to the snail peptide omega-conotoxin mviic. |
1995-11-07 |
2023-08-12 |
xenopus_laevis |
| C Mahotka, T E Hansen-Hagge, C R Bartra. Alternative splicing of T cell receptor (TCR) alpha chain transcripts containing V alpha 1 or V alpha 14 elements. Leukemia. vol 9. issue 10. 1995-11-07. PMID:7564513. |
a case in point are v delta 2d delta 3 and subsequent v delta 2d delta 3j alpha rearrangements observed in human leukemic pre-b cells as well as in normal lymphopoiesis. |
1995-11-07 |
2023-08-12 |
human |
| C Mahotka, T E Hansen-Hagge, C R Bartra. Alternative splicing of T cell receptor (TCR) alpha chain transcripts containing V alpha 1 or V alpha 14 elements. Leukemia. vol 9. issue 10. 1995-11-07. PMID:7564513. |
the functional expression of these unusual (vd) delta (jc) alpha hybrids is almost exclusively prevented by alternative splicing events. |
1995-11-07 |
2023-08-12 |
human |
| L A Gravestein, J D Nieland, A M Kruisbeek, J Bors. Novel mAbs reveal potent co-stimulatory activity of murine CD27. International immunology. vol 7. issue 4. 1995-11-06. PMID:7547681. |
as determined with one of the newly developed antibodies, murine cd27 is expressed on the great majority of both alpha beta and gamma delta t lymphocytes, on a small population of peripheral b cells, and on a very small subset of b220+ cells in the bone marrow. |
1995-11-06 |
2023-08-12 |
human |
| M C Mingari, C Vitale, A Cambiaggi, F Schiavetti, G Melioli, S Ferrini, A Pogg. Cytolytic T lymphocytes displaying natural killer (NK)-like activity: expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production. International immunology. vol 7. issue 4. 1995-11-06. PMID:7547697. |
the selected clones expressed either gamma delta or alpha beta tcr. |
1995-11-06 |
2023-08-12 |
Not clear |
| T Kumada, S Nakashima, Y Nakamura, H Miyata, Y Nozaw. Antigen-mediated phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells: possible involvement of calcium/calmodulin. Biochimica et biophysica acta. vol 1258. issue 2. 1995-11-06. PMID:7548173. |
rbl-2h3 cells express pkc alpha, beta, delta, epsilon and zeta isozymes and down-regulation of pkc by exposure to pma (20 nm) for 1-2 h caused rapid decrease in pkc alpha and beta isozymes, leaving pkc delta, epsilon and zeta isozymes intact. |
1995-11-06 |
2023-08-12 |
rat |
| J A Blendy, W Schmid, M Kiessling, G Schütz, P Gas. Effects of kainic acid induced seizures on immediate early gene expression in mice with a targeted mutation of the CREB gene. Brain research. vol 681. issue 1-2. 1995-11-06. PMID:7552295. |
the present study examined the response of immediate early genes following kainic acid induced seizures in mice lacking the alpha and delta isoforms of creb. |
1995-11-06 |
2023-08-12 |
mouse |
| J A Blendy, W Schmid, M Kiessling, G Schütz, P Gas. Effects of kainic acid induced seizures on immediate early gene expression in mice with a targeted mutation of the CREB gene. Brain research. vol 681. issue 1-2. 1995-11-06. PMID:7552295. |
these data suggest that creb alpha and delta are not required for the induction of immediate early genes following pharmacologically induced seizures. |
1995-11-06 |
2023-08-12 |
mouse |
| K Moreton, R Turner, N Blake, A Paton, N Groome, M Rumsb. Protein expression of the alpha, gamma, delta and epsilon subspecies of protein kinase C changes as C6 glioma cells become contact inhibited and quiescent in the presence of serum. FEBS letters. vol 372. issue 1. 1995-11-06. PMID:7556638. |
total protein kinase c (pkc) activity and protein expression of the alpha and delta subspecies of pkc increases markedly as c6 glioma cells grow from low cell density to the contact-inhibited quiescent state (also known as g(o)) in the presence of serum. |
1995-11-06 |
2023-08-12 |
Not clear |
| K Sugahara, H Tsuda, K Yoshida, S Yamada, T de Beer, J F Vliegenthar. Structure determination of the octa- and decasaccharide sequences isolated from the carbohydrate-protein linkage region of porcine intestinal heparin. The Journal of biological chemistry. vol 270. issue 39. 1995-11-06. PMID:7559427. |
their structures were determined by chemical and enzymatic analyses and 1h nmr spectroscopy and found to be the following octa- and decasaccharide sequences attached to ser in a molar ratio of 1.1:2.3:1.0:1.3: delta hexa(2s)alpha 1-4glcn(ns,6s)alpha 1-4glca beta 1-4glcnac alpha 1-4- glca beta 1-3gal beta 1-3gal beta 1-4xyl beta 1-o-ser (i), delta hexa(2s)alpha 1- 4glcn(ns,6s)alpha 1-4idoa alpha 1-4glcnac alpha 1-4glca beta 1- 3gal beta 1-3gal beta 1-4xyl beta 1-o-ser (ii), delta hexa(2s)alpha 1- 4glcn(ns,6s)alpha 1- 4idoa alpha 1-4glcnac alpha 1-4glca beta 1-4glcnac-alpha 1- 4glca beta 1-3gal beta 1-3gal beta 1-4xyl beta 1-o-ser (iii), delta hexa alpha 1-4glcn(ns,6s)alpha 1-4idoa alpha 1-4glcnac(6s)alpha 1- 4glca beta 1-3gal beta 1-3gal beta 1-4xyl beta 1-o-ser (iv) (delta hexa, glca, idoa, and glcn represent 4,5-unsaturated hexuronic acid, d-glucuronic acid, l-iduronic acid, and d-glucosamine, whereas 2s, 6s, and ns stand for 2-sulfate, 6-sulfate, and n-sulfate, respectively). |
1995-11-06 |
2023-08-12 |
Not clear |
| S J Moss, G H Gorrie, A Amato, T G Smar. Modulation of GABAA receptors by tyrosine phosphorylation. Nature. vol 377. issue 6547. 1995-11-06. PMID:7566089. |
they are presumed to be pentameric heteroligomers assembled from four classes of subunits with multiple members: alpha (1-6), beta (1-3), gamma (1-3) and delta (1). |
1995-11-06 |
2023-08-12 |
Not clear |
| E C Dudley, M Girardi, M J Owen, A C Hayda. Alpha beta and gamma delta T cells can share a late common precursor. Current biology : CB. vol 5. issue 6. 1995-11-03. PMID:7552177. |
alpha beta and gamma delta t cells can share a late common precursor. |
1995-11-03 |
2023-08-12 |
Not clear |
| E C Dudley, M Girardi, M J Owen, A C Hayda. Alpha beta and gamma delta T cells can share a late common precursor. Current biology : CB. vol 5. issue 6. 1995-11-03. PMID:7552177. |
the subdivision of t cells into alpha beta and gamma delta subtypes is conserved throughout vertebrate development. |
1995-11-03 |
2023-08-12 |
Not clear |
| E C Dudley, M Girardi, M J Owen, A C Hayda. Alpha beta and gamma delta T cells can share a late common precursor. Current biology : CB. vol 5. issue 6. 1995-11-03. PMID:7552177. |
the respective alpha beta and gamma delta t-cell receptors (tcrs) are encoded by somatically rearranged genes. |
1995-11-03 |
2023-08-12 |
Not clear |
| E C Dudley, M Girardi, M J Owen, A C Hayda. Alpha beta and gamma delta T cells can share a late common precursor. Current biology : CB. vol 5. issue 6. 1995-11-03. PMID:7552177. |
there has been broad speculation as to whether an individual thymocyte can become either a gamma delta t cell or an alpha beta t cell as a result of stochastic gene rearrangement processes, or whether the two types of t cell are derived from separate lineages. |
1995-11-03 |
2023-08-12 |
Not clear |