| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K L Knutson, M Hoeni. Arachidonic acid-induced down-regulation of protein kinase C delta in beta-cells. Journal of cellular biochemistry. vol 62. issue 4. 1997-03-31. PMID:8891899. |
in this report we studied the effects of arachidonic acid (aa) on the subcellular distribution of pkc alpha and pkc delta. |
1997-03-31 |
2023-08-12 |
Not clear |
| K L Knutson, M Hoeni. Arachidonic acid-induced down-regulation of protein kinase C delta in beta-cells. Journal of cellular biochemistry. vol 62. issue 4. 1997-03-31. PMID:8891899. |
aa has been reported to activate both pkc alpha and pkc delta and it is thought to be an important second messenger in beta-cells. |
1997-03-31 |
2023-08-12 |
Not clear |
| K L Knutson, M Hoeni. Arachidonic acid-induced down-regulation of protein kinase C delta in beta-cells. Journal of cellular biochemistry. vol 62. issue 4. 1997-03-31. PMID:8891899. |
here we report that aa interacted with and altered beta-cell pools of pkc delta preferentially over pkc alpha. |
1997-03-31 |
2023-08-12 |
Not clear |
| K L Knutson, M Hoeni. Arachidonic acid-induced down-regulation of protein kinase C delta in beta-cells. Journal of cellular biochemistry. vol 62. issue 4. 1997-03-31. PMID:8891899. |
the down-regulation of cytosolic pkc delta appeared to be isoform specific since cytosolic pkc alpha remained at control levels over the time course. |
1997-03-31 |
2023-08-12 |
Not clear |
| K L Knutson, M Hoeni. Arachidonic acid-induced down-regulation of protein kinase C delta in beta-cells. Journal of cellular biochemistry. vol 62. issue 4. 1997-03-31. PMID:8891899. |
indomethacin also down-regulated cytosolic pkc delta preferentially over pkc alpha possibly through accumulation of aa. |
1997-03-31 |
2023-08-12 |
Not clear |
| C I Robertson, K A Bartholomew, C P Novotny, R C Ullric. Deletion of the Schizophyllum commune A alpha locus: the roles of A alpha Y and Z mating-type genes. Genetics. vol 144. issue 4. 1997-03-31. PMID:8978032. |
we used the plasmid construction to produce an a alpha null (i.e., a alpha delta) strain by replacing the genomic y1 gene with ura1 in an a alpha 1 strain. |
1997-03-31 |
2023-08-12 |
Not clear |
| C I Robertson, K A Bartholomew, C P Novotny, R C Ullric. Deletion of the Schizophyllum commune A alpha locus: the roles of A alpha Y and Z mating-type genes. Genetics. vol 144. issue 4. 1997-03-31. PMID:8978032. |
to characterize the role of the a alpha genes in the regulation of sexual development, we transformed various a alpha y and z alleles into a alpha delta strains and examined the acquired mating types and mating abilities of the transformants. |
1997-03-31 |
2023-08-12 |
Not clear |
| J Arnaud, C Cayrou, R Llobera, B Rubi. Mutation in splicing consensus sequences causes lack of TCR membrane expression due to exon excision. Immunogenetics. vol 45. issue 5. 1997-03-31. PMID:9038103. |
the assembly defect seems to be that the truncated alpha chain does not interact with cd3 delta molecules; consequently, no tcr alphabeta/cd3 deltaepsilongammaepsilon complexes are formed. |
1997-03-31 |
2023-08-12 |
Not clear |
| A Schmidt, R L Vogel, K M Witherup, S J Rutledge, S M Pitzenberger, M Adam, G A Roda. Identification of fatty acid methyl ester as naturally occurring transcriptional regulators of the members of the peroxisome proliferator-activated receptor family. Lipids. vol 31. issue 11. 1997-03-28. PMID:8934443. |
the nuclear hormone receptors nuc-1 (ppar delta) and ppar alpha are members of the peroxisome proliferator-activated receptor (ppar) family. |
1997-03-28 |
2023-08-12 |
rat |
| U D Sohn, D Zoukhri, D Dartt, C Sergheraert, K M Harnett, J Behar, P Biancan. Different protein kinase C isozymes mediate lower esophageal sphincter tone and phasic contraction of esophageal circular smooth muscle. Molecular pharmacology. vol 51. issue 3. 1997-03-28. PMID:9058601. |
contraction of les cells was reduced by the alpha beta gamma pseudosubstrate but not by the alpha, delta, or epsilon pseudosubstrate. |
1997-03-28 |
2023-08-12 |
Not clear |
| U D Sohn, D Zoukhri, D Dartt, C Sergheraert, K M Harnett, J Behar, P Biancan. Different protein kinase C isozymes mediate lower esophageal sphincter tone and phasic contraction of esophageal circular smooth muscle. Molecular pharmacology. vol 51. issue 3. 1997-03-28. PMID:9058601. |
contraction of eso cells was reduced by the epsilon pseudosubstrate but not by the alpha, delta, or alpha beta gamma pseudosubstrate. |
1997-03-28 |
2023-08-12 |
Not clear |
| S J Romano, P C Pugh, J M McIntosh, D K Ber. Neuronal-type acetylcholine receptors and regulation of alpha 7 gene expression in vertebrate skeletal muscle. Journal of neurobiology. vol 32. issue 1. 1997-03-26. PMID:8989664. |
in addition, immunologic analysis with subunit-specific muscle antibodies shows that the alpha 7-containing species in muscle lacks the beta 1 and delta muscle achr gene products as it does the alpha 1. |
1997-03-26 |
2023-08-12 |
human |
| Y H Jiang, J R Lupton, R S Chapki. Dietary fish oil blocks carcinogen-induced down-regulation of colonic protein kinase C isozymes. Carcinogenesis. vol 18. issue 2. 1997-03-24. PMID:9054628. |
in order to elucidate the influence of dietary constituents on colonic intracellular signal transduction, the effect of different fats on rat colonic epithelial protein kinase c (pkc) alpha (classical), delta (novel) and lambda-zeta (atypical) expression was determined in carcinogen-treated animals. |
1997-03-24 |
2023-08-12 |
rat |
| E Mertsching, A Wilson, H R MacDonald, R Ceredi. T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. European journal of immunology. vol 27. issue 2. 1997-03-21. PMID:9045909. |
t cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. |
1997-03-21 |
2023-08-12 |
mouse |
| E Mertsching, A Wilson, H R MacDonald, R Ceredi. T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. European journal of immunology. vol 27. issue 2. 1997-03-21. PMID:9045909. |
t cells belong to two separate lineages based on surface expression of alpha beta or gamma delta t cell receptors (tcr). |
1997-03-21 |
2023-08-12 |
mouse |
| E Mertsching, A Wilson, H R MacDonald, R Ceredi. T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. European journal of immunology. vol 27. issue 2. 1997-03-21. PMID:9045909. |
since during thymus development tcr beta, gamma, and delta genes rearrange before alpha genes, and gamma delta cells appear earlier than alpha beta cells, it has been assumed that gamma delta cells are devoid of tcr alpha rearrangements. |
1997-03-21 |
2023-08-12 |
mouse |
| E Mertsching, A Wilson, H R MacDonald, R Ceredi. T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. European journal of immunology. vol 27. issue 2. 1997-03-21. PMID:9045909. |
we show here that this is not the case, since mature adult, but not fetal, thymic gamma delta cells undergo vj alpha rearrangements more frequently than immature alpha beta lineage thymic precursors. |
1997-03-21 |
2023-08-12 |
mouse |
| E Mertsching, A Wilson, H R MacDonald, R Ceredi. T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. European journal of immunology. vol 27. issue 2. 1997-03-21. PMID:9045909. |
sequence analysis shows vj alpha rearrangements in gamma delta cells to be mostly (70%) nonproductive. |
1997-03-21 |
2023-08-12 |
mouse |
| E Mertsching, A Wilson, H R MacDonald, R Ceredi. T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. European journal of immunology. vol 27. issue 2. 1997-03-21. PMID:9045909. |
furthermore, vj alpha rearrangements in gamma delta cells are transcribed normally and, as shown by analysis of tcr beta-/- mice, occur independently of productive vdj beta rearrangements. |
1997-03-21 |
2023-08-12 |
mouse |
| E Mertsching, A Wilson, H R MacDonald, R Ceredi. T cell receptor alpha gene rearrangement and transcription in adult thymic gamma delta cells. European journal of immunology. vol 27. issue 2. 1997-03-21. PMID:9045909. |
these data are interpreted in the context of a model in which precursors of alpha beta and gamma delta cells differ in their ability to express a functional pre-tcr complex. |
1997-03-21 |
2023-08-12 |
mouse |