| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rachmat Hidajat, Motoko Nagano-Fujii, Lin Deng, Motofumi Tanaka, Yuki Takigawa, Sohei Kitazawa, Hak Hott. Hepatitis C virus NS3 protein interacts with ELKS-{delta} and ELKS-{alpha}, members of a novel protein family involved in intracellular transport and secretory pathways. The Journal of general virology. vol 86. issue Pt 8. 2005-09-07. PMID:16033967. |
hepatitis c virus ns3 protein interacts with elks-{delta} and elks-{alpha}, members of a novel protein family involved in intracellular transport and secretory pathways. |
2005-09-07 |
2023-08-12 |
human |
| Pinkhas Sirota, Meital Meiman, Ruth Herschko, Hanna Bessle. Effect of neuroleptic administration on serum levels of soluble IL-2 receptor-alpha and IL-1 receptor antagonist in schizophrenic patients. Psychiatry research. vol 134. issue 2. 2005-09-01. PMID:15840416. |
there were positive correlations between both delta (baseline values minus endline values) il-1ra and delta sil-2r(alpha) levels and delta panss negative symptoms. |
2005-09-01 |
2023-08-12 |
human |
| Félix Freire, José Manuel Seco, Emilio Quiñoá, Ricardo Riguer. Determining the absolute stereochemistry of secondary/secondary diols by 1H NMR: basis and applications. The Journal of organic chemistry. vol 70. issue 10. 2005-08-23. PMID:15876061. |
the correlation between the nmr spectra of the bis-ester derivatives and the absolute stereochemistry of the diol involves the comparison of the chemical shifts of the signals for substituents r1/r2 and for the hydrogens attached to the two chiral centers [h(alpha)(r1) and h(alpha)(r2)] in the bis-(r)- and the bis-(s)-ester and is expressed as delta deltars. |
2005-08-23 |
2023-08-12 |
Not clear |
| Jan W Van Strien, Rogier E Hagenbeek, Cornelis J Stam, Serge A R B Rombouts, Frederik Barkho. Changes in brain electrical activity during extended continuous word recognition. NeuroImage. vol 26. issue 3. 2005-08-23. PMID:15955505. |
the lower-2 alpha 'old/new' effect most probably reflects attentional processes, whereas the theta and delta effects reflect encoding and retrieval processes. |
2005-08-23 |
2023-08-12 |
human |
| Manoj P Samant, Jozsef Gulyas, Doley J Hong, Glenn Croston, Catherine Rivier, Jean Rivie. Iterative approach to the discovery of novel degarelix analogues: substitutions at positions 3, 7, and 8. Part II. Journal of medicinal chemistry. vol 48. issue 15. 2005-08-23. PMID:16033265. |
substitutions at positions 3 ([n(beta)-(2-pyridyl-methyl)d-dap(3)]degarelix, ic(50) = 2.71 nm) (5), 7 ([pra(7)]degarelix, ic(50) = 2.11 nm) (16), and 8 ([n(delta)-(igly)orn(8)]degarelix, ic(50) = 1.38 nm) (20) and n-methylation ([n(alpha)-methyl-leu(7)]degarelix, ic(50) = 1.47 nm) (32) yielded analogues that were equipotent to degarelix (2) in vitro (ic(50) = 1.64 nm) but shorter acting in vivo. |
2005-08-23 |
2023-08-12 |
human |
| László Fodor, Tímea Bíró, Gábor Maksa. Nanomolar allopregnanolone potentiates rat cerebellar GABAA receptors. Neuroscience letters. vol 383. issue 1-2. 2005-08-22. PMID:15936524. |
nanomolar potentiation by allopregnanolone can be associated with cerebellar gaba(a) receptors containing alpha(6), beta(2-3) and delta subunits. |
2005-08-22 |
2023-08-12 |
rat |
| Alexander McFarlane, Christopher R Clark, Richard A Bryant, Leanne M Williams, Raymond Niaura, Robert H Paul, Brian L Hitsman, Laura Stroud, David M Alexander, Evian Gordo. The impact of early life stress on psychophysiological, personality and behavioral measures in 740 non-clinical subjects. Journal of integrative neuroscience. vol 4. issue 1. 2005-08-17. PMID:16035139. |
the between group differences were strongest in the eyes closed paradigm, where subjects who experienced els showed significantly reduced beta (f1,405=12.37, p=.000), theta (f1,405=20.48, p=.000), alpha (f1,405=9.65, p=.002) and delta power (f1,450=36.22, p=.000). |
2005-08-17 |
2023-08-12 |
human |
| Liza Leventhal, Scott Cosmi, Darlene Deeche. Effect of calcium channel modulators on temperature regulation in ovariectomized rats. Pharmacology, biochemistry, and behavior. vol 80. issue 3. 2005-08-16. PMID:15740794. |
gabapentin, reported to interact with the alpha(2)delta subunit of voltage-sensitive calcium channels and the l-type voltage-gated calcium channel blockers, verapamil and nifedipine, were examined. |
2005-08-16 |
2023-08-12 |
rat |
| Rika Kusumoto, Chikahide Masutani, Shizu Shimmyo, Shigenori Iwai, Fumio Hanaok. DNA binding properties of human DNA polymerase eta: implications for fidelity and polymerase switching of translesion synthesis. Genes to cells : devoted to molecular & cellular mechanisms. vol 9. issue 12. 2005-08-15. PMID:15569147. |
when two nucleotides have been incorporated into the primer beyond the tt dimer position, the pol eta-template/primer dna complex is destabilized, allowing dna synthesis by dna polymerases alpha or delta to resume. |
2005-08-15 |
2023-08-12 |
human |
| Attila Tóth, László Záborszky, László Détár. EEG effect of basal forebrain neuropeptide Y administration in urethane anaesthetized rats. Brain research bulletin. vol 66. issue 1. 2005-08-12. PMID:15925142. |
fronto-parietal eeg was recorded on both sides and relative eeg power was calculated in the delta (0-3 hz), theta (3-9 hz), alpha (9-16 hz) and beta (16-48 hz) frequency bands. |
2005-08-12 |
2023-08-12 |
rat |
| Jeong-Ho Kim, Kiyoshi Yamaguchi, Seong-Ho Lee, Patricia K Tithof, Gary S Sayler, Joo-Heon Yoon, Seung Joon Bae. Evaluation of polycyclic aromatic hydrocarbons in the activation of early growth response-1 and peroxisome proliferator activated receptors. Toxicological sciences : an official journal of the Society of Toxicology. vol 85. issue 1. 2005-08-01. PMID:15716483. |
in this study, we have evaluated whether pahs activate the early growth response (egr-1) gene and bind to peroxisome proliferator-activated receptor alpha (ppar alpha) and delta (ppar beta/delta) in cell culture systems. |
2005-08-01 |
2023-08-12 |
mouse |
| Matthew C Catley, Joanna E Chivers, Neil S Holden, Peter J Barnes, Robert Newto. Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells. British journal of pharmacology. vol 145. issue 1. 2005-07-28. PMID:15723090. |
this study used adenovirus delivery of a dominant inhibitor of nf-kappab (i kappa b alpha delta n) and dominant-negative ikk alpha (ikk alpha(km)) and ikk beta (ikk beta(ka)) to investigate the role of the individual ikks in nf-kappa b activation and inflammatory gene transcription by human pulmonary a549 cells. |
2005-07-28 |
2023-08-12 |
mouse |
| Matthew C Catley, Joanna E Chivers, Neil S Holden, Peter J Barnes, Robert Newto. Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells. British journal of pharmacology. vol 145. issue 1. 2005-07-28. PMID:15723090. |
overexpression of ikk beta(ka) or i kappa b alpha delta n prevented nf-kappa b-dependent transcription and dna binding. |
2005-07-28 |
2023-08-12 |
mouse |
| Matthew C Catley, Joanna E Chivers, Neil S Holden, Peter J Barnes, Robert Newto. Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells. British journal of pharmacology. vol 145. issue 1. 2005-07-28. PMID:15723090. |
similarly, ikk beta(ka) and i kappa b alpha delta n overexpression also inhibited il-1beta- and tnf alpha-dependent increases in icam-1, il-8 and gm-csf in addition to il-1beta-mediated increases in cyclooxygenase-2 expression, whereas ikk alpha(km) overexpression had little effect on these outputs. |
2005-07-28 |
2023-08-12 |
mouse |
| Matthew C Catley, Joanna E Chivers, Neil S Holden, Peter J Barnes, Robert Newto. Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells. British journal of pharmacology. vol 145. issue 1. 2005-07-28. PMID:15723090. |
this effect seemed to be directly related to ikk beta kinase activity since i kappa b alpha delta n only induced parp cleavage in tnf alpha-treated cells. |
2005-07-28 |
2023-08-12 |
mouse |
| Chih-Hsin Tang, Rong-Sen Yang, Wen-Mei F. Prostaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblasts. The Journal of biological chemistry. vol 280. issue 24. 2005-07-19. PMID:15833739. |
furthermore, treatment with antisense oligonucleotides of various pkc isoforms, including alpha, beta, epsilon, and delta, demonstrated that alpha isozyme plays an important role in the enhancement action of pge(2) on fn assembly. |
2005-07-19 |
2023-08-12 |
rat |
| M O Urban, K Ren, K T Park, B Campbell, N Anker, B Stearns, J Aiyar, M Belley, C Cohen, L Bristo. Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action. The Journal of pharmacology and experimental therapeutics. vol 313. issue 3. 2005-07-14. PMID:15734900. |
a recent report has suggested that binding to the alpha(2)delta subunit of voltage-gated calcium channels contributes to its antinociceptive effect, based on the stereoselective efficacy of two analogs: (1s,3r)3-methylgabapentin (3-megbp) (ic(50) = 42 nm), which is effective in neuropathic pain models; and (1r,3r)3-megbp (ic(50) > 10,000 nm), which is ineffective (field et al., 2000). |
2005-07-14 |
2023-08-12 |
rat |
| M O Urban, K Ren, K T Park, B Campbell, N Anker, B Stearns, J Aiyar, M Belley, C Cohen, L Bristo. Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action. The Journal of pharmacology and experimental therapeutics. vol 313. issue 3. 2005-07-14. PMID:15734900. |
thus, the stereoselective efficacy of 3-megbp, presumably related to alpha(2)delta binding, likely does not completely account for the mechanism of action of gbp. |
2005-07-14 |
2023-08-12 |
rat |
| Jonathon M Willets, Stefan R Nahorski, R A John Challis. Roles of phosphorylation-dependent and -independent mechanisms in the regulation of M1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 in hippocampal neurons. The Journal of biological chemistry. vol 280. issue 19. 2005-07-12. PMID:15743771. |
when co-expressed with the inositol 1,4,5-trisphosphate biosensor egfp-ph(plc delta), g protein-coupled receptor kinase 2 (grk2) can suppress m1 muscarinic acetylcholine (mach) receptor-mediated phospholipase c signaling in hippocampal neurons through a phosphorylation-independent mechanism, most likely involving the direct binding of the rgs homology domain of grk2 to g alpha(q/11). |
2005-07-12 |
2023-08-12 |
Not clear |
| Tony J Wigglesworth, David Sud, Tyler B Norsten, Vikram S Lekhi, Neil R Brand. Chiral discrimination in photochromic helicenes. Journal of the American Chemical Society. vol 127. issue 20. 2005-07-12. PMID:15898750. |
the magnitude of the optical rotation changed as much as delta[alpha]373 = 8698 degrees upon alternate irradiation with 400 nm and greater than 434 nm light. |
2005-07-12 |
2023-08-12 |
Not clear |