| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Merav Tauber, Yair Ben-Chai. Functional consequences of a rare human serotonergic 5-HT Frontiers in pharmacology. vol 14. 2023-10-05. PMID:37795037. |
functional consequences of a rare human serotonergic 5-ht serotonin (5-ht) plays a central role in various brain functions via the activation of a family of receptors, most of them g protein coupled receptors (gpcrs). |
2023-10-05 |
2023-10-07 |
human |
| Ifat Israel-Elgali, Hope Pan, Keren Oved, Nir Pillar, Gilad Levy, Boaz Barak, Ana Carneiro, David Gurwitz, Noam Shomro. Impaired myelin ultrastructure is reversed by citalopram treatment in a mouse model for major depressive disorder. Journal of psychiatric research. vol 166. 2023-09-27. PMID:37757703. |
the raphe nuclei (rn), located in the brain stem, consist of clusters of serotonergic (5-ht) neurons that project to almost all regions of the brain. |
2023-09-27 |
2023-10-07 |
mouse |
| Maria Letizia Minniti, Silvia Kalantari, Ludovica Pasca, Samantha Bruno, Sebastiano Arceri, Elisa Novello, Elisa Giorgio, Vittoria Rizzo, Renato Borgatti, Enza Maria Valente, Antonio Pisani, Simona Orcesi, Fabio Sirchi. Expanding the phenotype of Brunner syndrome from childhood to adulthood: Description of the second pediatric patient and his mother. American journal of medical genetics. Part A. 2023-09-26. PMID:37750385. |
given the serotonergic symptoms associated with high serotonin levels found in the mother, treatment with a serotonin reuptake inhibitor and dietary modifications were carried out, resulting in regression of the biochemical abnormalities and partial reduction of symptoms. |
2023-09-26 |
2023-10-07 |
Not clear |
| Kate Thomson, Cindy Karouta, Daniel Weber, Nichola Hoffmann, Ian Morgan, Tamsin Kelly, Regan Ashb. The role of the serotonergic system in atropine's anti-myopic effects. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 167. 2023-09-24. PMID:37742601. |
this may suggest that, although myopic growth can be inhibited through modulation of serotonergic receptor activity (by atropine or serotonergic antagonists), this does not require a change in serotonin levels. |
2023-09-24 |
2023-10-07 |
human |
| Katherine L Prowse, Harriett Law, Sergio Raez-Villanueva, Filip Markovic, Megan Wang, Rajka Borojevic, Sean P Parsons, Alexander D Vincent, Alison C Holloway, Elyanne M Ratcliff. Effects of American journal of physiology. Gastrointestinal and liver physiology. 2023-09-19. PMID:37724979. |
effects of perinatal exposure to selective serotonin reuptake inhibitors (ssris) has been shown to disrupt the development of serotonergic signaling pathways. |
2023-09-19 |
2023-10-07 |
rat |
| Yu Miyahara, Hideki Funahashi, Ayaka Haruta-Tsukamoto, Yoichiro Kogoh, Anna Kanemaru-Kawazoe, Yoji Hirano, Toshikazu Nishimori, Yasushi Ishid. Differential contribution of 5-HT Biological & pharmaceutical bulletin. 2023-09-18. PMID:37722878. |
differential contribution of 5-ht the involvement of serotonin (5-ht) and/or noradrenaline in acute pruriceptive processing in the central nervous system (cns) has been reported using antidepressants, such as milnacipran, a serotonin and noradrenaline reuptake inhibitor, and mirtazapine, a noradrenergic and specific serotonergic antidepressant; however, the roles of 5-ht receptor family in acute pruriceptive processing have not been fully elucidated in the cns. |
2023-09-18 |
2023-10-07 |
Not clear |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
to direct outgrowth, serotonergic neurons utilize serotonin as a signaling molecule prior to it assuming its neurotransmitter role. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
this process, termed serotonin autoregulation, regulates axon outgrowth, branching, and varicosity development of serotonergic neurons. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
using cultured drosophila serotonergic neurons, we found that exogenous serotonin reduced axon length and branching only in those expressing 5-ht1a. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Delaney R Long, Ava Kinser, Abby Olalde-Welling, Luke Brewer, Juri Lim, Dayle Matheny, Breanna Long, Douglas H Roossie. 5-HT1A regulates axon outgrowth in a subpopulation of Drosophila serotonergic neurons. Developmental neurobiology. 2023-09-15. PMID:37714743. |
altogether this suggests that 5-ht1a is a serotonin autoreceptor in a subpopulation of serotonergic neurons and initiates signaling pathways that regulate axon outgrowth and branching during drosophila development. |
2023-09-15 |
2023-10-07 |
drosophila_melanogaster |
| Mauro Chivite, Rosa M Ceinos, José M Cerdá-Reverter, Jose L Soengas, Manuel Aldegunde, Marcos A López-Patiño, Jesús M Mígue. Unraveling the periprandial changes in brain serotonergic activity and its correlation with food intake-related neuropeptides in rainbow trout Frontiers in endocrinology. vol 14. 2023-09-11. PMID:37693350. |
unraveling the periprandial changes in brain serotonergic activity and its correlation with food intake-related neuropeptides in rainbow trout this study explored changes in brain serotonin content and activity together with hypothalamic neuropeptide mrna abundance around feeding time in rainbow trout, as well as the effect of one-day fasting. |
2023-09-11 |
2023-10-07 |
Not clear |
| Xue Chen, Jing Li, Lisa Yu, Francesca Maule, Limei Chang, Jonathan Gallant, David J Press, Sheetal A Raithatha, Jillian M Hagel, Peter J Facchin. A cane toad (Rhinella marina) N-methyltransferase converts primary indolethylamines to tertiary psychedelic amines. The Journal of biological chemistry. 2023-09-10. PMID:37690691. |
since the therapeutic potential of psychedelics has been linked to activity at serotonergic receptors, we evaluated binding of derivatives at 5-ht |
2023-09-10 |
2023-10-07 |
Not clear |
| Nicolas Delestrée, Evangelia Semizoglou, John G Pagiazitis, Aleksandra Vukojicic, Estelle Drobac, Vasilissa Paushkin, George Z Menti. Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy. Brain : a journal of neurology. 2023-09-07. PMID:37678880. |
we also demonstrate that the 5-ht dysfunction is caused by smn deficiency in serotonergic neurons in the raphe nuclei of the brainstem. |
2023-09-07 |
2023-10-07 |
mouse |
| Nicolas Delestrée, Evangelia Semizoglou, John G Pagiazitis, Aleksandra Vukojicic, Estelle Drobac, Vasilissa Paushkin, George Z Menti. Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy. Brain : a journal of neurology. 2023-09-07. PMID:37678880. |
the behavioural significance of the dysfunction in serotonergic neuromodulation is underlined by inter-limb discoordination in sma mice, which is ameliorated when selective restoration of smn in 5-ht neurons is achieved by genetic means. |
2023-09-07 |
2023-10-07 |
mouse |
| Nicolas Delestrée, Evangelia Semizoglou, John G Pagiazitis, Aleksandra Vukojicic, Estelle Drobac, Vasilissa Paushkin, George Z Menti. Serotonergic dysfunction impairs locomotor coordination in spinal muscular atrophy. Brain : a journal of neurology. 2023-09-07. PMID:37678880. |
our study uncovers an unexpected dysfunction of serotonergic neuromodulation in sma and indicates that, if normal function is to be restored under disease conditions, 5-ht neuromodulation should be a key target for therapeutic approaches. |
2023-09-07 |
2023-10-07 |
mouse |
| Christopher R Brown, James D Foste. Palmitoylation Regulates Human Serotonin Transporter Activity, Trafficking, and Expression and Is Modulated by Escitalopram. ACS chemical neuroscience. 2023-08-30. PMID:37644775. |
during serotonergic transmission, the synaptic concentration of serotonin is tightly controlled in a spatial and temporal manner by the serotonin transporter (sert). |
2023-08-30 |
2023-09-07 |
human |
| Sarah Chaib, Benjamin Vidal, Caroline Bouillot, Ronan Depoortere, Adrian Newman-Tancredi, Luc Zimmer, Elise Levigoureu. Multimodal imaging study of the 5-HT NeuroImage. Clinical. vol 39. 2023-08-26. PMID:37632990. |
serotonergic neurons are involved in lid etiology and previous pre-clinical studies have shown that nlx-112, a 5-ht |
2023-08-26 |
2023-09-07 |
Not clear |
| Margot De Kooning, Iris Coppieters, Eva Huysmans, Jo Nijs, Mira Meeus, Lennard Voogt, Erwin Hendriks, Kelly Ickman. Unravelling Impaired Hypoalgesia at Rest and in Response to Exercise in Patients with Chronic Whiplash-Associated Disorders: Effects of a Single Administration of Selective Serotonin Reuptake Inhibitor versus Selective Norepinephrine Reuptake Inhibitor. Journal of clinical medicine. vol 12. issue 15. 2023-08-12. PMID:37568380. |
therefore, this study aimed to examine the isolated effect of activating serotonergic or noradrenergic descending pathways on hypoalgesia at rest and in response to exercise in patients with chronic wad by using respectively a single dose of a selective serotonin reuptake inhibitor (ssri) and a selective norepinephrine reuptake inhibitor (nri). |
2023-08-12 |
2023-08-16 |
human |
| Kristine Conde, Shuzheng Fang, Yong X. Unraveling the serotonin saga: from discovery to weight regulation and beyond - a comprehensive scientific review. Cell & bioscience. vol 13. issue 1. 2023-08-07. PMID:37550777. |
this review focuses on the history of serotonin, the state of current central serotonin research, previous serotonergic therapies, and the future of serotonin for treating individuals with obesity. |
2023-08-07 |
2023-08-14 |
Not clear |
| Chen-Cheng Lin, Chiu-Ping Yang, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Escitalopram reversibility of the impacts following chronic stress on central 5-HT profiles - Implications to depression and anxiety. Behavioural brain research. 2023-08-06. PMID:37544369. |
the success of using selective serotonin reuptake inhibitors (ssris) to treat these two disorders highlights the involvement of the central serotonergic (5-ht) system. |
2023-08-06 |
2023-08-14 |
rat |