| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Khalida Itriyev. Premenstrual syndrome and premenstrual dysphoric disorder in adolescents. Current problems in pediatric and adolescent health care. 2022-05-09. PMID:35534402. |
while the pathophysiology of these premenstrual disorders remains unclear, it has been hypothesized that sensitivity to hormonal fluctuations during the luteal phase of the menstrual cycle, abnormal serotonergic activity, and aberrations in progesterone and the neurotransmitter gamma aminobutyric acid (gaba) may all play a role in these disorders. |
2022-05-09 |
2023-08-13 |
Not clear |
| Béla Kiss, Balázs Krámos, István Laszlovszk. Potential Mechanisms for Why Not All Antipsychotics Are Able to Occupy Dopamine D Frontiers in psychiatry. vol 13. 2022-04-11. PMID:35401257. |
the first line of treatment of schizophrenia are antipsychotics, a class of medications that targets several neurotransmitter receptors in the brain, including dopaminergic, serotonergic, adrenergic and/or muscarinic receptors, depending on the given agent. |
2022-04-11 |
2023-08-13 |
Not clear |
| Steven F Dobrowolski, Yu Leng Phua, Jerry Vockley, Eric Goetzman, Harry C Blai. Phenylketonuria oxidative stress and energy dysregulation: Emerging pathophysiological elements provide interventional opportunity. Molecular genetics and metabolism. 2022-04-05. PMID:35379539. |
low tyr and trp concentrations generate secondary serotonergic and dopaminergic neurotransmitter paucities, widely attributed as drivers of pku neurologic phenotypes. |
2022-04-05 |
2023-08-13 |
Not clear |
| Gizelle N K Fauss, Kelsey E Hudson, James W Gra. Role of Descending Serotonergic Fibers in the Development of Pathophysiology after Spinal Cord Injury (SCI): Contribution to Chronic Pain, Spasticity, and Autonomic Dysreflexia. Biology. vol 11. issue 2. 2022-02-25. PMID:35205100. |
recent research has shown that the loss of descending serotonergic activity is accompanied by a shift in how the neurotransmitter gaba affects neural activity, reducing its inhibitory effect. |
2022-02-25 |
2023-08-13 |
Not clear |
| Fan Lei, Hong Sun, Wei-Hua Wang, Fang Wei, Xin-Chun Luo, Rui Luo, Li-Jun D. [Comparative proteomic profiling of hippocampi in mice treated with Jingui Shenqi Pills and Liuwei Dihuang Pills]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 3. 2022-02-18. PMID:35178953. |
the proteins up-regulated by jingui were mainly involved in membrane transport, synaptic vesicle cycle, serotonergic synapse, dopaminergic synapse and so on, suggesting that jingui may play a role in promoting the transport of neurotransmitter in the nervous system. |
2022-02-18 |
2023-08-13 |
mouse |
| Emma Aaldijk, Yannick Vermeire. The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease: a narrative review. Ageing research reviews. 2022-01-06. PMID:34990844. |
additionally, a substantial amount of preclinical trials highlight the potential of diet, fecal microbiota transplantations, as well as pre- and probiotics in modulating the brain's serotonergic neurotransmitter system, starting from the gut. |
2022-01-06 |
2023-08-13 |
mouse |
| Chongyang Tang, Peng Ren, Kaiqiang Ma, Siyang Li, Xiongfei Wang, Yuguang Guan, Jian Zhou, Tianfu Li, Xia Liang, Guoming Lua. The correspondence between morphometric MRI and metabolic profile in Rasmussen's encephalitis. NeuroImage. Clinical. vol 33. 2021-12-24. PMID:34952352. |
re-related gm volumetric atrophy was spatially correlated with hypomebolism in fdg uptake, and with spatial distribution of the dopaminergic and serotonergic neurotransmitter systems. |
2021-12-24 |
2023-08-13 |
human |
| Nadine Huber, Dorit Hoffmann, Raisa Giniatullina, Hannah Rostalski, Stina Leskelä, Mari Takalo, Teemu Natunen, Eino Solje, Anne M Remes, Rashid Giniatullin, Mikko Hiltunen, Annakaisa Haapasal. C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction. Neurobiology of disease. 2021-12-16. PMID:34915153. |
ftld is accompanied by changes in several neurotransmitter systems, including the glutamatergic, gabaergic, dopaminergic, and serotonergic systems and many clinical symptoms can be explained by disturbances in these systems. |
2021-12-16 |
2023-08-13 |
mouse |
| Deepak Kumar, Ashish Sharma, Rajeev Taliyan, Maiko T Urmera, Oscar Herrera-Calderon, Thomas Heinbockel, Shafiqur Rahman, Rohit Goya. Orchestration of the circadian clock and its association with Alzheimer's disease: Role of endocannabinoid signaling. Ageing research reviews. vol 73. 2021-12-11. PMID:34844016. |
literature also suggests that cannabinoids may alter activity of suprachiasmatic nucleus by influencing the activity of their major neurotransmitter γ-aminobutyric acid or by interacting indirectly with the suprachiasmatic nucleus's two other major inputs i.e., the geniculo-hypothalamic tract-mediated release of neuropeptide y and serotonergic inputs from the dorsal raphe nuclei. |
2021-12-11 |
2023-08-13 |
Not clear |
| Sanders A McDougall, Jasmine A M Robinson, Devon C Gleason, Laura L Cotte. Reciprocal cross-sensitization between cocaine and RU 24969 in male and female preweanling rats. Pharmacology, biochemistry, and behavior. vol 209. 2021-11-25. PMID:34437872. |
neuronal adaptations involving dopaminergic, glutamatergic, and serotonergic neurotransmitter systems are responsible for behavioral sensitization. |
2021-11-25 |
2023-08-13 |
rat |
| Nadine Huber, Sonja Korhonen, Dorit Hoffmann, Stina Leskelä, Hannah Rostalski, Anne M Remes, Paavo Honkakoski, Eino Solje, Annakaisa Haapasal. Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration-Insights into disease mechanisms and current therapeutic approaches. Molecular psychiatry. 2021-11-20. PMID:34799692. |
changes in several neurotransmitter systems including the glutamatergic, gabaergic, dopaminergic, and serotonergic systems have been reported in ftld spectrum disease patients. |
2021-11-20 |
2023-08-13 |
Not clear |
| Farhat Bano, Naheed Akhte. Hypophagic and weight reducing effect of Momardica charinta fruit by Enhancing 5-HT neurotransmitter in rats brain. Pakistan journal of pharmaceutical sciences. vol 33. issue 5(Special). 2021-11-16. PMID:33832887. |
the present research is big contribution of momardicacharinta activity as weight reducing plant through serotonergic neurotransmitter decrease in body weight and food intake might be due to increased concentration of serotonin in their respective receptors in brain, which produce hypophagic effect in rats treated with water extract of momardicacharinttia. |
2021-11-16 |
2023-08-13 |
human |
| Chunyan Yao, Zhiyuan Wang, Huiyong Jiang, Ren Yan, Qianfei Huang, Yin Wang, Hui Xie, Ying Zou, Ying Yu, Longxian L. Ganoderma lucidum promotes sleep through a gut microbiota-dependent and serotonin-involved pathway in mice. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:34211003. |
glaa administration increased the levels of the sleep-promoting neurotransmitter 5-hydroxytryptamine and the tph2, iptr3 and gng13 transcripts in the sleep-regulating serotonergic synapse pathway in the hypothalamus during this process. |
2021-11-08 |
2023-08-13 |
mouse |
| Judith Stemick, Carina Gauer, Jeanette Wihan, Sandra Moceri, Wei Xiang, Stephan von Hörsten, Zacharias Kohl, Jürgen Winkle. Compensatory neuritogenesis of serotonergic afferents within the striatum of a transgenic rat model of Parkinson's disease. Brain research. vol 1748. 2021-10-25. PMID:32919983. |
in parallel, the serotonergic autoreceptor levels involved in a serotonergic negative feedback loop were reduced within the striatum, suggesting a dysfunctional neurotransmitter release. |
2021-10-25 |
2023-08-13 |
human |
| Chris Baeken, Yanfeng Xu, Guo-Rong Wu, Robrecht Dockx, Kathelijne Peremans, Rudi De Raed. Hostility in medication-resistant major depression and comorbid generalized anxiety disorder is related to increased hippocampal-amygdala 5-HT European archives of psychiatry and clinical neuroscience. vol 271. issue 7. 2021-10-25. PMID:33904978. |
although both disorders are treated with serotonergic based psychotropic agents, little is known on the influence of the serotonergic neurotransmitter system on the occurrence of comorbid gad when clinically depressed. |
2021-10-25 |
2023-08-13 |
Not clear |
| Ronald M Harper, Hannah C Kinne. Potential Mechanisms of Failure in the Sudden Infant Death Syndrome. Current pediatric reviews. vol 6. issue 1. 2021-10-21. PMID:22792083. |
the evidence ranges from subtle physiological signs that appear very early in life, to autopsy findings of altered neurotransmitter, including serotonergic, systems that have extensive roles in breathing, cardiovascular regulation, and thermal control. |
2021-10-21 |
2023-08-12 |
Not clear |
| Trevor Archer, Marlene Oscar-Berman, Kenneth Blum, Mark Gol. Neurogenetics and Epigenetics in Impulsive Behaviour: Impact on Reward Circuitry. Journal of genetic syndromes & gene therapy. vol 3. issue 3. 2021-10-21. PMID:23264884. |
brain-derived neurotrophic factor (bdnf) affects the development and integrity of the noradrenergic, dopaminergic, serotonergic, glutamatergic, and cholinergic neurotransmitter systems, and plasma levels of the neurotrophin are associated with both cognitive and aggressive impulsiveness. |
2021-10-21 |
2023-08-12 |
Not clear |
| Ramani S Durvasula, Charles H Hinki. Neuropsychological Dysfunction among HIV Infected Drug Abusers. American journal of infectious diseases. vol 2. issue 2. 2021-10-20. PMID:20467580. |
damage to neurotransmitter systems including the dopaminergic, serotonergic and glutamatergic systems which are affected by both stimulant use and hiv is an alternate explanation. |
2021-10-20 |
2023-08-12 |
human |
| Pavel A Markin, Alex Brito, Natalia E Moskaleva, Franco Tagliaro, Vadim V Tarasov, Michael R La Frano, Mark V Savitskii, Svetlana A Appolonov. Short- and medium-term exposures of diazepam induce metabolomic alterations associated with the serotonergic, dopaminergic, adrenergic and aspartic acid neurotransmitter systems in zebrafish (Danio rerio) embryos/larvae. Comparative biochemistry and physiology. Part D, Genomics & proteomics. vol 38. 2021-10-04. PMID:33610025. |
short- and medium-term exposures of diazepam induce metabolomic alterations associated with the serotonergic, dopaminergic, adrenergic and aspartic acid neurotransmitter systems in zebrafish (danio rerio) embryos/larvae. |
2021-10-04 |
2023-08-13 |
zebrafish |
| Erika Sarno, Adam J Moeser, Alfred J Robiso. Neuroimmunology of depression. Advances in pharmacology (San Diego, Calif.). vol 91. 2021-10-01. PMID:34099111. |
these include pro-inflammatory signaling, alterations in the hypothalamic-pituitary-adrenal axis, dysregulation of the serotonergic and noradrenergic neurotransmitter systems, neuroinflammation, and meningeal immune dysfunction. |
2021-10-01 |
2023-08-13 |
Not clear |