Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Yuki Kambe, Junichi Sakaguchi, Honami Setoyama, Akihiro Yamanaka, Tomoyuki Kuwak. Involvement of supralemniscal nucleus (B9) 5-HT neuronal system in nociceptive processing: a fiber photometry study. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:32005128. |
as main pathways of das, it is well known that dorsal raphe (b6/b7) - rostral ventromedial medulla (b3) - spinal dorsal horn includes serotonergic system. |
2021-02-12 |
2023-08-13 |
mouse |
M K Chung, S Wang, J Yang, I Alshanqiti, F Wei, J Y R. Neural Pathways of Craniofacial Muscle Pain: Implications for Novel Treatments. Journal of dental research. vol 99. issue 9. 2021-02-02. PMID:32374638. |
descending serotonergic circuits from the rostral ventromedial medulla facilitate activation of second-order neurons in the trigeminal nucleus complex, which leads to the maintenance of mechanical hyperalgesia of inflamed masseter muscle. |
2021-02-02 |
2023-08-13 |
Not clear |
Yaqun Li, Dong Ho Kang, Woong Mo Kim, Hyung Gon Lee, Seung Hoon Kim, Hyun Eung You, Jeong Il Choi, Myung Ha Yoo. Systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla. The Korean journal of pain. vol 34. issue 1. 2021-01-12. PMID:33380568. |
systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla. |
2021-01-12 |
2023-08-13 |
rat |
Maureen M Sampson, Katherine M Myers Gschweng, Ben J Hardcastle, Shivan L Bonanno, Tyler R Sizemore, Rebecca C Arnold, Fuying Gao, Andrew M Dacks, Mark A Frye, David E Krant. Serotonergic modulation of visual neurons in Drosophila melanogaster. PLoS genetics. vol 16. issue 8. 2020-09-23. PMID:32866139. |
subcellular mapping with gfp-tagged 5-ht2b and 5-ht1a constructs indicated that these receptors localize to layer m2 of the medulla, proximal to serotonergic boutons, suggesting that the medulla neuropil is the primary site of serotonergic regulation for these neurons. |
2020-09-23 |
2023-08-13 |
drosophila_melanogaster |
Ryan Patel, Anthony H Dickenso. Modality selective roles of pro-nociceptive spinal 5-HT Neuropharmacology. vol 143. 2019-02-25. PMID:30240783. |
chronic pain states are frequently associated with enhanced descending excitatory drive mediated predominantly through serotonergic neurones in the rostral ventromedial medulla. |
2019-02-25 |
2023-08-13 |
Not clear |
Fiona M Bright, Roger W Byard, Robert Vink, David S Paterso. Normative distribution of substance P and its tachykinin neurokinin-1 receptor in the medullary serotonergic network of the human infant during postnatal development. Brain research bulletin. vol 137. 2018-08-31. PMID:29331576. |
we examined the normative distribution of sp and nk1r in the serotonergic (5-hydroxytryptamine, [5-ht]) network of the human infant medulla during postnatal development, to provide a baseline to facilitate future analysis of the sp/nk1r system and its interaction with 5-ht within pediatric brainstem disorders in early life. |
2018-08-31 |
2023-08-13 |
human |
Elizabeth A Coon, Ann M Schmeichel, Joseph E Parisi, Matthew D Cykowski, Phillip A Low, Eduardo E Benarroc. Medullary neuronal loss is not associated with α-synuclein burden in multiple system atrophy. Movement disorders : official journal of the Movement Disorder Society. vol 31. issue 12. 2017-12-29. PMID:27629118. |
the aim of this study was to determine the extent of loss of adrenergic neurons in the rostral ventrolateral medulla and serotonergic neurons in the ventrolateral medulla and raphe nuclei and its relationship with α-synuclein accumulation. |
2017-12-29 |
2023-08-13 |
Not clear |
Scott A Givan, Kevin J Cumming. Intermittent severe hypoxia induces plasticity within serotonergic and catecholaminergic neurons in the neonatal rat ventrolateral medulla. Journal of applied physiology (Bethesda, Md. : 1985). vol 120. issue 11. 2017-12-14. PMID:26968026. |
intermittent severe hypoxia induces plasticity within serotonergic and catecholaminergic neurons in the neonatal rat ventrolateral medulla. |
2017-12-14 |
2023-08-13 |
rat |
Frederico G Graef. Translational approach to the pathophysiology of panic disorder: Focus on serotonin and endogenous opioids. Neuroscience and biobehavioral reviews. vol 76. issue Pt A. 2017-10-30. PMID:28073587. |
the first suggests that panic patients have deficient serotonergic inhibition of neurons localized in the dorsal periaqueductal gray matter of the midbrain that organizes defensive reactions to cope with proximal threats as well as of sympathomotor control areas of the rostral ventrolateral medulla that generate neurovegetative symptoms of the panic attack. |
2017-10-30 |
2023-08-13 |
human |
Caroline Sévoz-Couche, Charly Brouillar. Key role of 5-HT Neuroscience and biobehavioral reviews. vol 74. issue Pt B. 2017-10-27. PMID:27131969. |
the nucleus tractus solitarii (nts) in the medulla is an area of viscerosomatic integration innervated by both central and peripheral serotonergic fibers. |
2017-10-27 |
2023-08-13 |
Not clear |
Ryosuke Morinaga, Nobuaki Nakamuta, Yoshio Yamamot. Hypoxia-induced increases in serotonin-immunoreactive nerve fibers in the medulla oblongata of the rat. Acta histochemica. vol 118. issue 8. 2017-01-23. PMID:27825705. |
hypoxia induces respiratory responses in mammals and serotonergic neurons in the medulla oblongata participate in respiratory control. |
2017-01-23 |
2023-08-13 |
rat |
Milena De Felice, Michael H Ossipo. Cortical and subcortical modulation of pain. Pain management. vol 6. issue 2. 2016-12-20. PMID:26984039. |
these sites can have a bimodal influence on the serotonergic and noradrenergic descending pain modulatory systems via communications among the periaqueductal gray, rostral ventromedial medulla and pontine noradrenergic nuclei, ultimately either facilitating or inhibiting further nociceptive inputs. |
2016-12-20 |
2023-08-13 |
Not clear |
Kamilla Blecharz-Klin, Ilona Joniec-Maciejak, Katarzyna Jawna, Justyna Pyrzanowska, Agnieszka Piechal, Adriana Wawer, Ewa Widy-Tyszkiewic. Developmental exposure to paracetamol causes biochemical alterations in medulla oblongata. Environmental toxicology and pharmacology. vol 40. issue 2. 2016-06-29. PMID:26233562. |
this experiment shows that prenatal and early life paracetamol exposure modulates neurotransmission associated with serotonergic, noradrenergic and dopaminergic system in medulla oblongata. |
2016-06-29 |
2023-08-13 |
rat |
Sergey S Panteleev, Alexandra А Martseva, Olga А Lyubashin. The inhibitory effect of granisetron on ventrolateral medulla neuron responses to colorectal distension in rats. European journal of pharmacology. vol 749. 2015-11-16. PMID:25595728. |
a key pathophysiological mechanism of abdominal pain is associated with disturbances of serotonergic transmission in feedback control loops of endogenous pain modulation in which the ventrolateral medulla (vlm) plays an important role. |
2015-11-16 |
2023-08-13 |
rat |
Cheng Liu, Tao-Tao Liu, Zhi-Gang He, Bin Shu, Hong-Bing Xian. Inhibition of itch-related responses by selectively ablated serotonergic signals at the rostral ventromedial medulla in mice. International journal of clinical and experimental pathology. vol 7. issue 12. 2015-10-30. PMID:25674265. |
inhibition of itch-related responses by selectively ablated serotonergic signals at the rostral ventromedial medulla in mice. |
2015-10-30 |
2023-08-13 |
mouse |
M Gesto, M A López-Patiño, J Hernández, J L Soengas, J M Mígue. Gradation of the stress response in rainbow trout exposed to stressors of different severity: the role of brain serotonergic and dopaminergic systems. Journal of neuroendocrinology. vol 27. issue 2. 2015-10-21. PMID:25523118. |
the three stress protocols induced increases in the serotonergic activity in all brain regions analysed (hypothalamus, telencephalon and medulla oblongata), independently of the duration of the handling disturbance, whereas the effects on the dopaminergic system were minor and brain region-dependent. |
2015-10-21 |
2023-08-13 |
Not clear |
Raffaele Nardone, Yvonne Höller, Aljoscha Thomschewski, Peter Höller, Piergiorgio Lochner, Stefan Golaszewski, Francesco Brigo, Eugen Trink. Serotonergic transmission after spinal cord injury. Journal of neural transmission (Vienna, Austria : 1996). vol 122. issue 2. 2015-09-25. PMID:24866695. |
there are functional relevant connections between the descending serotonergic system from the rostral ventromedial medulla in the brainstem, the 5-ht receptors in the spinal dorsal horn, and the descending pain facilitation after tissue and nerve injury. |
2015-09-25 |
2023-08-13 |
Not clear |
Ingvar J Rognum, Hoa Tran, Elisabeth A Haas, Keith Hyland, David S Paterson, Robin L Haynes, Kevin G Broadbelt, Brian J Harty, Othon Mena, Henry F Krous, Hannah C Kinne. Serotonin metabolites in the cerebrospinal fluid in sudden infant death syndrome. Journal of neuropathology and experimental neurology. vol 73. issue 2. 2014-03-13. PMID:24423636. |
previously, we reported multiple serotonergic (5-ht) abnormalities in nuclei of the medulla oblongata that help mediate protective responses to homeostatic stressors. |
2014-03-13 |
2023-08-12 |
human |
A A Coley, V A Ruffin, F J Moss, U Hopfer, W F Boro. Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons. Neuroscience. vol 246. 2014-02-24. PMID:23500099. |
the medullary raphé (mr) of the medulla oblongata contains chemosensitive neurons that respond to increases in arterial [co₂], by altering firing rate, with increases being associated with serotonergic (5-hydroxytryptamine [5ht]) neurons and decreases, with gabaergic neurons. |
2014-02-24 |
2023-08-12 |
mouse |
Yasuo Id. [Pregabalin (Lyrica)]. Masui. The Japanese journal of anesthesiology. vol 62. issue 7. 2013-11-04. PMID:23905403. |
the descending facilitating serotonergic system from rostral ventromedial medulla may have effects on the occurrence and maintenance for the chronic pain. |
2013-11-04 |
2023-08-12 |
Not clear |