| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Alonso, O Brun, J L Ridet, M Geffard, N Chauve. Non-dopaminergic catecholaminergic neurons of mesencephalic and medullary nuclei contain different levels of dopamine. Journal of chemical neuroanatomy. vol 9. issue 3. 1996-03-22. PMID:8588834. |
these data indicate that two types of non-dopaminergic catecholaminergic neurons can be distinguished according to their content in dopamine: (i) the noradrenergic and adrenergic neurons located in the medulla oblongata, whose cell bodies and axons contain high concentrations of metabolic dopamine and (ii) the noradrenergic neurons located in the mesencephalon, which contain low levels of metabolic dopamine. |
1996-03-22 |
2023-08-12 |
Not clear |
| E Nwanze, F Souverbie, G Jonsson, E Sundströ. Regional biotransformation of MPTP in the CNS of rodents and its relation to neurotoxicity. Neurotoxicology. vol 16. issue 3. 1996-03-18. PMID:8584278. |
neither previous lesions of catecholamine terminals in striatum or the frontal cortex, nor pretreatment with a dopamine uptake blocker affected the synthesis of mpp+, showing that the conversion of mptp to mpp+ is taking place outside both dopaminergic and noradrenergic neurons. |
1996-03-18 |
2023-08-12 |
mouse |
| P H Yu, B A Davis, X Zhang, D M Zuo, J Fang, C T Lai, X M Li, I A Paterson, A A Boulto. Neurochemical, neuroprotective and neurorescue effects of aliphatic N-methylpropargylamines; new MAO-B inhibitors without amphetamine-like properties. Progress in brain research. vol 106. 1996-03-15. PMID:8584647. |
some of these compounds protect mouse nigrostriatal dopamine neurons against the neurotoxin mptp and the mouse hippocampal noradrenergic system against the neurotoxin n-(2-chloroethyl)-n-ethyl-2-bromobenzylamine (dsp-4). |
1996-03-15 |
2023-08-12 |
mouse |
| M Tárczy, I Szirma. Failure of dopamine metabolism: borderlines of parkinsonism and dementia. Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma. vol 66. issue 3-4. 1996-03-14. PMID:8578941. |
several factors may take part in the development of cognitive impairment: i/ defective function of subcortico-cortical pathways including the mesocorticolimbic dopamine deficiency with cell loss in medial substantia nigra, the degeneration of noradrenergic, serotonergic and cholinergic systems ii/ cortical and limbic alzheimer pathology iii/ cortical lewy bodies iv/ vascular alterations. |
1996-03-14 |
2023-08-12 |
Not clear |
| Q Y Zhou, R D Palmite. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell. vol 83. issue 7. 1996-02-21. PMID:8548806. |
mice unable to synthesize dopamine (da) specifically in dopaminergic neurons were created by inactivating the tyrosine hydroxylase (th) gene then by restoring th function in noradrenergic cells. |
1996-02-21 |
2023-08-12 |
mouse |
| H Ishii, S Shigetomi, S Niimura, H Sanada, S Fukuch. Postprandial changes in noradrenergic and dopaminergic activity in patients with essential hypertension. Hypertension research : official journal of the Japanese Society of Hypertension. vol 18 Suppl 1. 1996-01-26. PMID:8529062. |
the ratio of norepinephrine to dopamine following in eh was significantly greater than that in n. from these results, it is suggested that the feeding-induced stimulation of noradrenergic activity may be a result from the decrease in blood pressure, and that the blunted response of dopaminergic activity in eh may reflect the enhanced conversion of dopamine to norepinephrine probably due to the enhanced activity of dopamine beta-hydroxylase in the sympathetic nerves. |
1996-01-26 |
2023-08-12 |
human |
| L Moons, E D'Hondt, K Pijcke, F Vandesand. Noradrenergic system in the chicken brain: immunocytochemical study with antibodies to noradrenaline and dopamine-beta-hydroxylase. The Journal of comparative neurology. vol 360. issue 2. 1996-01-25. PMID:8522651. |
the present study on the distribution of the noradrenergic system in the brain of the chicken combined with the results of a previous report on the distribution of l-dopa and dopamine in the same species (l. moons, j. van gils, e. ghijsels, and f. vandesande, 1994, j. comp. |
1996-01-25 |
2023-08-12 |
chicken |
| M J Picklo, R G Wiley, S Lonce, D A Lappi, D Robertso. Anti-dopamine beta-hydroxylase immunotoxin-induced sympathectomy in adult rats. The Journal of pharmacology and experimental therapeutics. vol 275. issue 2. 1995-12-19. PMID:7473126. |
anti-dopamine beta-hydroxylase immunotoxin (dhit) is an antibody-targeted noradrenergic lesioning tool comprised of a monoclonal antibody against the noradrenergic enzyme, dopamine beta-hydroxylase, conjugated to saporin, a ribosome-inactivating protein. |
1995-12-19 |
2023-08-12 |
rat |
| D King, J M Finla. Effects of selective dopamine depletion in medial prefrontal cortex on basal and evoked extracellular dopamine in neostriatum. Brain research. vol 685. issue 1-2. 1995-11-30. PMID:7583236. |
in this study, we demonstrate that 6-hydroxydopamine (6-ohda) can be used to produce a lesion of dopamine (da) terminals in medial prefrontal cortex (mpfc) while sparing the noradrenergic innervation in this region. |
1995-11-30 |
2023-08-12 |
rat |
| R D Spealma. Noradrenergic involvement in the discriminative stimulus effects of cocaine in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562595. |
the results support a role for norepinephrine uptake and alpha-1 adrenoceptor mechanisms in the ds effects of cocaine, possibly reflecting a facilitory noradrenergic influence on mesocorticolimbic dopamine activity. |
1995-11-21 |
2023-08-12 |
human |
| R H Schmidt, M S Grad. Loss of forebrain cholinergic neurons following fluid-percussion injury: implications for cognitive impairment in closed head injury. Journal of neurosurgery. vol 83. issue 3. 1995-10-12. PMID:7666229. |
there was no visible effect of head injury on forebrain dopamine or noradrenergic innervation. |
1995-10-12 |
2023-08-12 |
human |
| S Shigetomi, S Fukuch. Recent aspect of the role of peripheral dopamine and its receptors in the pathogenesis of hypertension. Fukushima journal of medical science. vol 40. issue 2. 1995-09-21. PMID:7642168. |
dopamine is an essential and indispensable catecholamine, which acts not only as a neurotransmitter in dopaminergic and noradrenergic sympathetic neurons but also as an autocrine/paracrine substance in non-neuronal tissues. |
1995-09-21 |
2023-08-12 |
rat |
| F Fornai, M G Alessandrì, F Fascetti, F Vaglini, G U Corsin. Clonidine suppresses 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced reductions of striatal dopamine and tyrosine hydroxylase activity in mice. Journal of neurochemistry. vol 65. issue 2. 1995-08-24. PMID:7616226. |
at the same time, evidence is accumulating that the endogenous noradrenergic system plays a protective role in mptp-induced striatal dopamine (da) depletion and nigral dopaminergic cell death. |
1995-08-24 |
2023-08-12 |
mouse |
| P J Gresch, A F Sved, M J Zigmond, J M Finla. Local influence of endogenous norepinephrine on extracellular dopamine in rat medial prefrontal cortex. Journal of neurochemistry. vol 65. issue 1. 1995-07-26. PMID:7790854. |
noradrenergic and dopaminergic projections converge in the medial prefrontal cortex and there is evidence of an interaction between dopamine (da) and norepinephrine (ne) terminals in this region. |
1995-07-26 |
2023-08-12 |
rat |
| F Amin, M Davidson, R S Kahn, J Schmeidler, R Stern, P J Knott, S Apte. Assessment of the central dopaminergic index of plasma HVA in schizophrenia. Schizophrenia bulletin. vol 21. issue 1. 1995-07-06. PMID:7770741. |
under fasting conditions, the dopamine (da) metabolite homovanillic acid (hva) in plasma originates mainly from central da neurons or from central and peripheral noradrenergic (na) neurons. |
1995-07-06 |
2023-08-12 |
Not clear |
| M Ito, K Shichijo, M Nakashima, T Nakayama, S Naito, K Tsuchiya, I Sekin. Gastric mucosal blood flow in relation to stress-induced hypercontraction in spontaneously hypertensive rats. The Japanese journal of physiology. vol 44. issue 6. 1995-06-29. PMID:7760525. |
noradrenergic innervation, noradrenaline and dopamine contents in the muscle layer were significantly greater in shr than in wky, and tissue choline acetyltransferase activity was significantly lower in shr. |
1995-06-29 |
2023-08-12 |
rat |
| G M Peterso. Sprouting of central noradrenergic fibers in the dentate gyrus following combined lesions of its entorhinal and septal afferents. Hippocampus. vol 4. issue 6. 1995-05-10. PMID:7704108. |
the noradrenergic identity of the fibers was indicated by immunoreactivity for dopamine beta hydroxylase (dbh) and peripheral sympathetic fibers were demonstrated by immunoreactivity for nerve growth factor receptor (ngfr), which did not stain cholinergic fibers in this application. |
1995-05-10 |
2023-08-12 |
rat |
| M J Picklo, R G Wiley, D A Lappi, D Robertso. Noradrenergic lesioning with an anti-dopamine beta-hydroxylase immunotoxin. Brain research. vol 666. issue 2. 1995-04-13. PMID:7882029. |
to circumvent these drawbacks, an immunotoxin was constructed using a monoclonal antibody against the noradrenergic specific enzyme dopamine beta-hydroxylase (d beta h) coupled via a disulfide bond to saporin, a ribosomal inactivating protein. |
1995-04-13 |
2023-08-12 |
rat |
| M Kokaia, M A Cenci, E Elmér, O G Nilsson, Z Kokaia, J Bengzon, A Björklund, O Lindval. Seizure development and noradrenaline release in kindling epilepsy after noradrenergic reinnervation of the subcortically deafferented hippocampus by superior cervical ganglion or fetal locus coeruleus grafts. Experimental neurology. vol 130. issue 2. 1995-03-27. PMID:7867765. |
in both lc- and scg-grafted animals, dopamine beta-hydroxylase immunocytochemistry demonstrated a high density of graft-derived noradrenergic fibers in the dorsal hippocampus, whereas reinnervation of the ventral hippocampus was much more sparse. |
1995-03-27 |
2023-08-12 |
rat |
| N Singewald, C Schneider, A Pfitscher, A Philipp. In vivo release of catecholamines in the locus coeruleus. Naunyn-Schmiedeberg's archives of pharmacology. vol 350. issue 4. 1995-03-07. PMID:7845470. |
the observed differences in the release characteristics between noradrenaline on the one hand and dopamine and adrenaline on the other might indicate that noradrenaline is partly released from somatodendritic sites of the noradrenergic cell bodies in the locus coeruleus. |
1995-03-07 |
2023-08-12 |
Not clear |