| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shigeharu Tsuda, Jiamei Hou, Floyd J Thompson, Prodip K Bos. Traumatic brain injury-induced anxiety: Injury and plasticity of the central noradrenergic system. Experimental neurology. 2025-02-10. PMID:39929384. |
following the elevated plus maze tests to longitudinally assess anxiety-like behavior at 2 and 18 weeks post-injury of tbi animals, brain tissues of naïve and tbi rats were coronally sectioned and immunostained for a noradrenergic (na) marker (dopamine β-hydroxylase) and neuronal nuclei in the central na production sites and critical anxiety-regulating brain structures. |
2025-02-10 |
2025-02-13 |
human |
| Jeffrey L Cummings, Malaak Brubaker, Katherine J Selzler, Sarah T Gonzalez, Mehul Patel, Stephen M Stah. An overview of the pathophysiology of agitation in Alzheimer's dementia with a focus on neurotransmitters and circuits. CNS spectrums. 2024-10-22. PMID:39438777. |
the authors present a model of agitation in alzheimer's dementia in which noradrenergic hyperactivity along with serotonergic deficits and dysregulated striatal dopamine release contribute to agitated and aggressive behaviors. |
2024-10-22 |
2024-10-25 |
Not clear |
| Antonio Verduzco-Mendoza, Daniel Mota-Rojas, Adriana Olmos-Hernández, Alberto Avila-Luna, Karla García-García, Arturo Gálvez-Rosas, Alberto Hidalgo-Bravo, Camilo Ríos, Carmen Parra-Cid, Sergio Montes, Julieta García-López, Laura E Ramos-Languren, Francisca Pérez-Severiano, Rigoberto González-Piña, Antonio Bueno-Nav. Changes in Noradrenergic Synthesis and Dopamine Beta-Hydroxylase Activity in Response to Oxidative Stress after Iron-induced Brain Injury. Neurochemical research. 2024-08-06. PMID:39105899. |
changes in noradrenergic synthesis and dopamine beta-hydroxylase activity in response to oxidative stress after iron-induced brain injury. |
2024-08-06 |
2024-08-08 |
rat |
| Antonio Verduzco-Mendoza, Daniel Mota-Rojas, Adriana Olmos-Hernández, Alberto Avila-Luna, Karla García-García, Arturo Gálvez-Rosas, Alberto Hidalgo-Bravo, Camilo Ríos, Carmen Parra-Cid, Sergio Montes, Julieta García-López, Laura E Ramos-Languren, Francisca Pérez-Severiano, Rigoberto González-Piña, Antonio Bueno-Nav. Changes in Noradrenergic Synthesis and Dopamine Beta-Hydroxylase Activity in Response to Oxidative Stress after Iron-induced Brain Injury. Neurochemical research. 2024-08-06. PMID:39105899. |
the present study investigated whether iron-induced cortical injury modulated noradrenergic synthesis and dopamine beta-hydroxylase (dbh) activity in response to oxidative stress in the brain cortex, pons and cerebellum of the rat. |
2024-08-06 |
2024-08-08 |
rat |
| Jessica L Maples-Keller, Laura Watkins, Natalie Hellman, Nathaniel L Phillips, Barbara O Rothbau. Treatment Approaches for Posttraumatic Stress Disorder Derived from Basic Research on Fear Extinction. Biological psychiatry. 2024-07-20. PMID:39032727. |
pharmacological, behavioral, and device-based augmentation strategies of ptsd treatment based in basic science findings are reviewed, including those that disrupt noradrenergic receptor processes, medications that act on nmda receptors, physical exercise, cannabinoids, estradiol, dexamethasone, yohimbine, losartan, dopamine, and mdma, along with the evidence for their efficacy in human clinical samples. |
2024-07-20 |
2024-07-24 |
human |
| Vitaly Ryu, Anisa Azatovna Gumerova, Ronit Witztum, Funda Korkmaz, Liam Cullen, Hasni Kannangara, Ofer Moldavski, Orly Barak, Daria Lizneva, Ki A Goosens, Sarah Stanley, Se-Min Kim, Tony Yuen, Mone Zaid. An atlas of brain-bone sympathetic neural circuits in mice. eLife. vol 13. 2024-07-04. PMID:38963696. |
histological studies show abundant sns innervation of the periosteum and bone marrow-these nerves consist of noradrenergic fibers that immunostain for tyrosine hydroxylase, dopamine beta hydroxylase, or neuropeptide y. |
2024-07-04 |
2024-07-10 |
mouse |
| Vitaly Ryu, Anisa Gumerova, Ronit Witztum, Funda Korkmaz, Hasni Kannangara, Ofer Moldavski, Orly Barak, Daria Lizneva, Ki A Goosens, Sarah Stanley, Se-Min Kim, Tony Yuen, Mone Zaid. An Atlas of Brain-Bone Sympathetic Neural Circuits. bioRxiv : the preprint server for biology. 2024-02-19. PMID:38370676. |
histological studies show abundant sns innervation of the periosteum and bone marrow--these nerves consist of noradrenergic fibers that immunostain for tyrosine hydroxylase, dopamine beta hydroxylase, or neuropeptide y. |
2024-02-19 |
2024-02-21 |
Not clear |
| Ana Perez-Villalba, María Salomé Sirerol-Piquer, Raúl Soriano-Cantón, Virginia Folgado, Azucena Pérez-Cañamás, Martina Kirstein, Isabel Fariñas, Francisco Pérez-Sánche. Dopaminergic neuron loss in mice due to increased levels of wild-type human α-Synuclein only takes place under conditions of accelerated aging. Scientific reports. vol 14. issue 1. 2024-01-30. PMID:38291230. |
these motor disturbances correlate with reduced dopamine (da) levels, increased da turnover, synaptic terminal loss, and notably, the depletion of dopaminergic neurons in the substantia nigra and noradrenergic neurons in the locus coeruleus. |
2024-01-30 |
2024-02-02 |
mouse |
| Marta Louçano, Ana Coelho, Sílvia Sousa Chambel, Cristina Prudêncio, Célia Duarte Cruz, Isaura Tavare. Noradrenergic Pathways Involved in Micturition in an Animal Model of Hydrocephalus-Implications for Urinary Dysfunction. Biomedicines. vol 12. issue 1. 2024-01-23. PMID:38255319. |
since our previous characterization of the lc in hydrocephalic animals showed increased levels of noradrenaline, we then evaluated the noradrenergic innervation of the spinal cord's onuf's nucleus by measuring levels of dopamine β-hydroxylase (dbh). |
2024-01-23 |
2024-01-25 |
rat |
| Dorothy Tse, Lucia Privitera, Anna C Norton, Francesco Gobbo, Patrick Spooner, Tomonori Takeuchi, Stephen J Martin, Richard G M Morri. Cell-type-specific optogenetic stimulation of the locus coeruleus induces slow-onset potentiation and enhances everyday memory in rats. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 46. 2023-11-06. PMID:37931094. |
despite the locus coeruleus being considered a primarily noradrenergic area, both effects of such stimulation were blocked by the dopamine d1/d5 receptor antagonist sch 23390. |
2023-11-06 |
2023-11-08 |
rat |
| Paula Trujillo, Megan A Aumann, Daniel O Claasse. Neuromelanin-sensitive MRI as a promising biomarker of catecholamine function. Brain : a journal of neurology. 2023-09-05. PMID:37669320. |
disruptions to dopamine and noradrenergic neurotransmission are noted in several neurodegenerative and psychiatric disorders. |
2023-09-05 |
2023-10-07 |
Not clear |
| Jesús E Yepez, Jorge Juáre. Atomoxetine promotes incentive value of modafinil and sensitizes exploratory behavior. Pharmacology, biochemistry, and behavior. vol 230. 2023-08-20. PMID:37595803. |
the role of dopamine in the addictive effect of psychostimulants is well known; however, the involvement of the noradrenergic system is still unclear and poorly understood, though drugs like cocaine and amphetamines are known to exert significant activity on this system. |
2023-08-20 |
2023-09-07 |
rat |
| Ellen Tedford, Norhidayah Binti Badya, Conor Laing, Nozomi Asaoka, Shuji Kaneko, Beatrice Maria Filippi, Glenn Alan McConke. Infection-induced extracellular vesicles evoke neuronal transcriptional and epigenetic changes. Scientific reports. vol 13. issue 1. 2023-04-27. PMID:37106020. |
tinev (toxoplasma-induced neuronal extracellular vesicles) isolated from infected noradrenergic cells down-regulated dopamine ß-hydroxylase (dbh) gene expression in human and rodent cells. |
2023-04-27 |
2023-08-14 |
human |
| Anna Volnova, Natalia Kurzina, Anastasia Belskaya, Arina Gromova, Arseniy Pelevin, Maria Ptukha, Zoia Fesenko, Alla Ignashchenkova, Raul R Gainetdino. Noradrenergic Modulation of Learned and Innate Behaviors in Dopamine Transporter Knockout Rats by Guanfacine. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672730. |
noradrenergic modulation of learned and innate behaviors in dopamine transporter knockout rats by guanfacine. |
2023-01-21 |
2023-08-14 |
rat |
| Anna Volnova, Natalia Kurzina, Anastasia Belskaya, Arina Gromova, Arseniy Pelevin, Maria Ptukha, Zoia Fesenko, Alla Ignashchenkova, Raul R Gainetdino. Noradrenergic Modulation of Learned and Innate Behaviors in Dopamine Transporter Knockout Rats by Guanfacine. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672730. |
in this study, we assessed the effects of repeated and acute administration of α2a-adrenoceptor agonist guanfacine on innate and learned forms of behavior of dopamine transporter knockout (dat-ko) rats to evaluate the possible noradrenergic modulation of behavioral deficits. |
2023-01-21 |
2023-08-14 |
rat |
| Bernacka Joanna, Kielbinski Michal, Wawrzczak-Bargieła Agnieszka, Zajda Katarzyna, Maćkowiak Marzena, Przewlocki Ryszard, Solecki Wojciec. Alpha-2A but not 2B/C noradrenergic receptors in ventral tegmental area regulate phasic dopamine release in nucleus accumbens core. Neuropharmacology. 2022-09-18. PMID:36116534. |
alpha-2a but not 2b/c noradrenergic receptors in ventral tegmental area regulate phasic dopamine release in nucleus accumbens core. |
2022-09-18 |
2023-08-14 |
Not clear |
| Resha Khanal, Sharad Oli, Janet Chan Gomez, Sahar Tahir, Binita Bhandari, Saketram Komandur. Severe Case of Oral Baclofen Withdrawal Resulting in Mechanical Ventilation. Journal of investigative medicine high impact case reports. vol 10. 2022-03-31. PMID:35356848. |
abrupt stoppage causes activation of dopamine and noradrenergic receptors causing muscle spasms, tremors, hyperpyrexia, delusions, hallucination, and delirium. |
2022-03-31 |
2023-08-13 |
Not clear |
| Deshdeepak Ratna, Birendra Mallic. Pedunculo-pontine tegmentum cholinergic REM-ON neurons modulate ventral tegmental neurons to modulate rapid eye movement sleep in rats. Neuropharmacology. 2022-01-04. PMID:34982973. |
the interaction among the acetylcholine (ach)-ergic rem-on neurons in the pedunculo-pontine area (ppt), noradrenergic rem-off neurons in locus coeruleus (lc) and gaba-ergic neurons in the regulation of rapid eye movement sleep (rems) have been studied in relative details; however, many questions including the role of dopamine (da) remain unanswered. |
2022-01-04 |
2023-08-13 |
rat |
| Michele Protti, Roberto Mandrioli, Camilla Marasca, Andrea Cavalli, Alessandro Serretti, Laura Mercolin. New-generation, non-SSRI antidepressants: Drug-drug interactions and therapeutic drug monitoring. Part 2: NaSSAs, NRIs, SNDRIs, MASSAs, NDRIs, and others. Medicinal research reviews. vol 40. issue 5. 2021-10-28. PMID:32285503. |
in this second part of the review, focused on new-generation antidepressants not included among selective serotonin reuptake inhibitors, the following classes are considered: noradrenergic and selective serotonergic antidepressants; norepinephrine reuptake inhibitors; serotonin, norepinephrine and dopamine reuptake inhibitors; melatonergic agonists and selective serotonergic antagonists; norepinephrine and dopamine reuptake inhibitors; and so forth. |
2021-10-28 |
2023-08-13 |
Not clear |
| Mostafa El Mansari, Mohammad Ebrahimzadeh, Rami Hamati, Chidibere M Iro, Bence Farkas, Béla Kiss, Nika Adham, Pierre Blie. Long-term administration of cariprazine increases locus coeruleus noradrenergic neurons activity and serotonin Journal of psychopharmacology (Oxford, England). vol 34. issue 10. 2021-10-28. PMID:32684081. |
long-term administration of cariprazine increases locus coeruleus noradrenergic neurons activity and serotonin cariprazine, the novel dopamine (da) d |
2021-10-28 |
2023-08-13 |
Not clear |