| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sophie Virachit, Kathryn J Mathews, Veronica Cottam, Eryn Werry, Emilia Galli, Elisabeth Rappou, Pӓivi Lindholm, Mart Saarma, Glenda M Halliday, Cynthia Shannon Weickert, Kay L Doubl. Levels of glial cell line-derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in Parkinson's disease. Brain pathology (Zurich, Switzerland). vol 29. issue 6. 2020-04-06. PMID:31033033. |
in the pd hippocampus, protein levels of glial cell line-derived neurotrophic factor were significantly decreased, despite no evidence of neuronal loss. |
2020-04-06 |
2023-08-13 |
Not clear |
| Anke Hoffmann, Michael Ziller, Dietmar Spengle. Progress in iPSC-Based Modeling of Psychiatric Disorders. International journal of molecular sciences. vol 20. issue 19. 2020-02-12. PMID:31581684. |
in addition, the formation of hippocampal circuit-like structures in vitro is impaired in patients with scz as is the case for glia development. |
2020-02-12 |
2023-08-13 |
human |
| Xinyu Zhang, Xianzhi Shen, Jiali Dong, Wen-Cao Liu, Min Song, Yanyun Sun, Hui Shu, Clare-Louise Towse, Wenlan Liu, Chun-Feng Liu, Xinchun Ji. Inhibition of Reactive Astrocytes with Fluorocitrate Ameliorates Learning and Memory Impairment Through Upregulating CRTC1 and Synaptophysin in Ischemic Stroke Rats. Cellular and molecular neurobiology. vol 39. issue 8. 2020-01-20. PMID:31270712. |
deregulated glia gap junction communication, which is reflected by increased protein levels of glial fibrillary acidic protein (gfap) and connexin 43 (cx43), has been observed in ischemic hippocampus and has been associated with cognitive impairment in animal stroke models. |
2020-01-20 |
2023-08-13 |
rat |
| Takafumi Mizushige, Dai Nogimura, Akitoshi Nagai, Haruka Mitsuhashi, Yuki Taga, Masashi Kusubata, Shunji Hattori, Yukihito Kabuyam. Ginger-Degraded Collagen Hydrolysate Exhibits Antidepressant Activity in Mice. Journal of nutritional science and vitaminology. vol 65. issue 3. 2020-01-09. PMID:31257265. |
gdch significantly increased gene expression of glial cell line-derived neurotrophic factor (gdnf) and ciliary neurotrophic factor (cntf) in the hippocampus, molecules that affect the differentiation and survival of neurons, relative to that in the control condition. |
2020-01-09 |
2023-08-13 |
mouse |
| Claudia Metzler-Baddeley, Jilu P Mole, Rebecca Sims, Fabrizio Fasano, John Evans, Derek K Jones, John P Aggleton, Roland J Baddele. Author Correction: Fornix white matter glia damage causes hippocampal gray matter damage during age-dependent limbic decline. Scientific reports. vol 9. issue 1. 2020-01-08. PMID:31619745. |
author correction: fornix white matter glia damage causes hippocampal gray matter damage during age-dependent limbic decline. |
2020-01-08 |
2023-08-13 |
Not clear |
| Shilpa Borehalli Mayegowda, Christofer Thoma. Glial pathology in neuropsychiatric disorders: a brief review. Journal of basic and clinical physiology and pharmacology. vol 30. issue 4. 2020-01-06. PMID:31280243. |
alteration in glial cell function predominantly targets three main brain regions - the prefrontal cortex, limbic areas including the hippocampus, and the amygdala, which have been extensively studied by various researchers across the globe. |
2020-01-06 |
2023-08-13 |
Not clear |
| Qie Shuyan, Gong Weijun, Xi Jianin, Wang Congxiao, Wang Luyi, Yue Shouwe. Glia activation of eukaryotic translation initiation factor 4e-binding protein 1 in temporal lobe epilepsy. Neuroreport. vol 30. issue 3. 2019-12-26. PMID:30672889. |
taken together, we investigated the spatiotemporal expression of p4ebp1 in the sclerotic hippocampus of both patients and a ka-induced mouse model and found glia activation of 4e-binding protein 1 in tle. |
2019-12-26 |
2023-08-13 |
mouse |
| Min Wen, Lin Ding, Lingyu Zhang, Tiantian Zhang, Yanagita Teruyoshi, Yuming Wang, Changhu Xu. Eicosapentaenoic Acid-Enriched Phosphatidylcholine Mitigated Aβ1-42-Induced Neurotoxicity via Autophagy-Inflammasome Pathway. Journal of agricultural and food chemistry. vol 67. issue 49. 2019-12-19. PMID:31722531. |
the spatial memory ability and the biochemical changes in the hippocampus were measured, including glial cell activation, tumor necrosis factor α production, nlrp3 inflammasome activation, and autophagic flux. |
2019-12-19 |
2023-08-13 |
human |
| Defne A Amado, Julianne M Rieders, Fortunay Diatta, Pilar Hernandez-Con, Adina Singer, Jordan T Mak, Junxian Zhang, Eric Lancaster, Beverly L Davidson, Alice S Chen-Plotki. AAV-Mediated Progranulin Delivery to a Mouse Model of Progranulin Deficiency Causes T Cell-Mediated Toxicity. Molecular therapy : the journal of the American Society of Gene Therapy. vol 27. issue 2. 2019-12-16. PMID:30559071. |
we found that, despite a global increase in progranulin, overexpression resulted in dramatic and selective hippocampal toxicity and degeneration affecting neurons and glia. |
2019-12-16 |
2023-08-13 |
mouse |
| Hoffman, Olson, Kreisma. The role of taurine for cellular volume regulation of the hippocampus Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. vol 7. issue 10. 2019-11-20. PMID:11015266. |
the role of taurine for cellular volume regulation of the hippocampus taurine is used for volume regulation in a number of cultured cells, including neurons and glia. |
2019-11-20 |
2023-08-12 |
rat |
| S. Shoham, D. C. Javitt, U. Heresco-Lev. High dose glycine nutrition affects glial cell morphology in rat hippocampus and cerebellum. The international journal of neuropsychopharmacology. vol 2. issue 1. 2019-11-20. PMID:11281969. |
high dose glycine nutrition affects glial cell morphology in rat hippocampus and cerebellum. |
2019-11-20 |
2023-08-12 |
rat |
| Sabah Khan, Nadira Y Yuldasheva, Trevor F C Batten, Alasdair R Pickles, Katherine A B Kellett, Sikha Sah. Tau pathology and neurochemical changes associated with memory dysfunction in an optimised murine model of global cerebral ischaemia - A potential model for vascular dementia? Neurochemistry international. vol 118. 2019-09-16. PMID:29649504. |
the results show consistent and selective neuronal and glial cell changes in the hippocampus and the cortex together with significant reductions in glt1 (***p < 0.001), vglut1 (**p < 0.01) and vglut2 (***p < 0.001) expressions in the hippocampus in occluded mice as compared to sham-operated animals. |
2019-09-16 |
2023-08-13 |
mouse |
| Jiajia Zhu, Xing Li, Jia Yin, Yafang Hu, Yong Gu, Suyue Pa. Glycocalyx degradation leads to blood-brain barrier dysfunction and brain edema after asphyxia cardiac arrest in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 38. issue 11. 2019-08-12. PMID:28825336. |
mechanistically, haase treatment further increased ca/cpr-induced activation of glia cells and expression of inflammatory factors, whereas hc decreased them in the brain cortex and hippocampus. |
2019-08-12 |
2023-08-13 |
rat |
| Laura K Cole, Jin Hee Kim, Andrew A Amoscato, Yulia Y Tyurina, Hülya Bay R, Benyamin Karimi, Tabrez J Siddiqui, Valerian E Kagan, Grant M Hatch, Tiina M Kauppine. Aberrant cardiolipin metabolism is associated with cognitive deficiency and hippocampal alteration in tafazzin knockdown mice. Biochimica et biophysica acta. Molecular basis of disease. vol 1864. issue 10. 2019-05-20. PMID:30055293. |
since reduced cl levels has also been reported in numerous neurodegenerative disorders, we examined how taz-deficiency impacts cognitive abilities, brain mitochondrial respiration and the function of hippocampal neurons and glia in taz knockdown (taz kd) mice. |
2019-05-20 |
2023-08-13 |
mouse |
| Maria Elvira Brocca, Luciana Pietranera, Edo Ronald de Kloet, Alejandro Federico De Nicol. Mineralocorticoid Receptors, Neuroinflammation and Hypertensive Encephalopathy. Cellular and molecular neurobiology. vol 39. issue 4. 2019-05-17. PMID:30117098. |
then oxidative stress caused by vasculopathy and hypoxia further increases mr activation in hippocampal neurons and glia cells, activates microglia activation and pro-inflammatory mediators, and down-regulates anti-inflammatory factors. |
2019-05-17 |
2023-08-13 |
human |
| Hannah Hochgerner, Amit Zeisel, Peter Lönnerberg, Sten Linnarsso. Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing. Nature neuroscience. vol 21. issue 2. 2019-05-16. PMID:29335606. |
these findings demonstrate the fundamental similarity of postnatal and adult neurogenesis in the hippocampus and pinpoint the early postnatal transformation of radial glia from embryonic progenitors to adult quiescent stem cells. |
2019-05-16 |
2023-08-13 |
mouse |
| Simon Cervenk. Immune sculpting of the psychotic brain? In vivo associations between a glial cell marker and hippocampal morphology. Brain, behavior, and immunity. vol 74. 2019-05-13. PMID:30077591. |
in vivo associations between a glial cell marker and hippocampal morphology. |
2019-05-13 |
2023-08-13 |
Not clear |
| Chun-Lei Han, Ming Ge, Yun-Peng Liu, Xue-Min Zhao, Kai-Liang Wang, Ning Chen, Wen-Jia Meng, Wei Hu, Jian-Guo Zhang, Liang Li, Fan-Gang Men. LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy. Journal of neuroinflammation. vol 15. issue 1. 2019-04-08. PMID:29636074. |
lncrna h19 contributes to hippocampal glial cell activation via jak/stat signaling in a rat model of temporal lobe epilepsy. |
2019-04-08 |
2023-08-13 |
rat |
| Chun-Lei Han, Ming Ge, Yun-Peng Liu, Xue-Min Zhao, Kai-Liang Wang, Ning Chen, Wen-Jia Meng, Wei Hu, Jian-Guo Zhang, Liang Li, Fan-Gang Men. LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy. Journal of neuroinflammation. vol 15. issue 1. 2019-04-08. PMID:29636074. |
we therefore speculated that h19 is involved in the hippocampal glial cell activation during epileptogenesis. |
2019-04-08 |
2023-08-13 |
rat |
| Seon-Ah Chong, Silvia Balosso, Catherine Vandenplas, Gregory Szczesny, Etienne Hanon, Kasper Claes, Xavier Van Damme, Bénédicte Danis, Jonathan Van Eyll, Christian Wolff, Annamaria Vezzani, Rafal M Kaminski, Isabelle Niespodzian. Intrinsic Inflammation Is a Potential Anti-Epileptogenic Target in the Organotypic Hippocampal Slice Model. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 15. issue 2. 2019-03-13. PMID:29464573. |
we combined organotypic hippocampal slice cultures, representing an in vitro model of post-traumatic epilepsy, with multi-electrode array recordings to directly monitor the development of epileptiform activity and to examine the concomitant changes in cytokine release, cell death, and glial cell activation. |
2019-03-13 |
2023-08-13 |
Not clear |