| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Voulgari-Kokota, R Fairless, M Karamita, V Kyrargyri, V Tseveleki, M Evangelidou, B Delorme, P Charbord, R Diem, L Prober. Mesenchymal stem cells protect CNS neurons against glutamate excitotoxicity by inhibiting glutamate receptor expression and function. Experimental neurology. vol 236. issue 1. 2012-08-07. PMID:22561409. |
the adoptive transfer of egfp(+)msc in a mouse kainic acid epilepsy model also provided neuroprotection against glutamate excitotoxicity in vivo, as shown by reduced neuron damage and glial cell activation in the hippocampus. |
2012-08-07 |
2023-08-12 |
mouse |
| Tomoya Kamide, Yasuko Kitao, Toshiaki Takeichi, Akiko Okada, Hiromi Mohri, Ann Marie Schmidt, Takayuki Kawano, Seiichi Munesue, Yasuhiko Yamamoto, Hiroshi Yamamoto, Jun-ichiro Hamada, Osamu Hor. RAGE mediates vascular injury and inflammation after global cerebral ischemia. Neurochemistry international. vol 60. issue 3. 2012-06-25. PMID:22202666. |
rt-pcr and immunohistochemical analysis revealed that expression of rage was induced in the vascular cells at 12 h, and then in the neurons and glia from 3 to 7 days in the hippocampus after bccao. |
2012-06-25 |
2023-08-12 |
mouse |
| João M N Duarte, Samira G Ferreira, Rui A Carvalho, Rodrigo A Cunha, Attila Köfalv. CB₁ receptor activation inhibits neuronal and astrocytic intermediary metabolism in the rat hippocampus. Neurochemistry international. vol 60. issue 1. 2012-06-20. PMID:22085448. |
we labelled hippocampal slices with the tracers [2-¹³c]acetate, which is oxidized in glial cells, and [u-¹³c]glucose, which is metabolized both in glia and neurons, to evaluate metabolic compartmentation between glia and neurons. |
2012-06-20 |
2023-08-12 |
rat |
| R W Irwin, J Yao, J To, R T Hamilton, E Cadenas, R D Brinto. Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function. Journal of neuroendocrinology. vol 24. issue 1. 2012-06-01. PMID:22070562. |
up-regulated proteins included pyruvate dehydrogenase, atp synthase, manganese superoxide dismutase and peroxiredoxin v. in vitro, whole cell metabolism was assessed in live primary cultured hippocampal neurones and mixed glia. |
2012-06-01 |
2023-08-12 |
rat |
| Ronald S Duman, Bhavya Volet. Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents. Trends in neurosciences. vol 35. issue 1. 2012-05-15. PMID:22217452. |
basic and clinical studies demonstrate that stress and depression are associated with atrophy and loss of neurons and glia, which contribute to the decreased size and function of limbic brain regions that control mood and depression, including the prefrontal cortex and hippocampus. |
2012-05-15 |
2023-08-12 |
Not clear |
| Hidemitsu Nakajima, Takeya Kubo, Yuko Semi, Masanori Itakura, Mitsuru Kuwamura, Takeshi Izawa, Yasu-Taka Azuma, Tadayoshi Takeuch. A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain. Journal of biotechnology. vol 157. issue 2. 2012-05-09. PMID:22079868. |
following in vivo delivery, targeted accell sirnas were incorporated successfully into various types of mature neurons, but not glia, for 1 week in diverse brain regions (cortex, striatum, hippocampus, midbrain, and cerebellum) with an efficacy of delivery of approximately 97%. |
2012-05-09 |
2023-08-12 |
rat |
| Olivier Pascual, Sarrah Ben Achour, Philippe Rostaing, Antoine Triller, Alain Bessi. Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 4. 2012-03-28. PMID:22167804. |
in the adult hippocampus, microglia are the other major glial cell type. |
2012-03-28 |
2023-08-12 |
Not clear |
| Richelle Mychasiuk, Robbin Gibb, Bryan Kol. Prenatal bystander stress induces neuroanatomical changes in the prefrontal cortex and hippocampus of developing rat offspring. Brain research. vol 1412. 2012-02-21. PMID:21816391. |
dendritic architecture (dendritic length, branch order, and spine density) along with cell quantification (neuron and glia) was generated for layer 3 pyramidal cells of the medial prefrontal cortex (mpfc/cg3), orbital prefrontal cortex (ofc/aid), and ca1 of the hippocampus. |
2012-02-21 |
2023-08-12 |
rat |
| Evangelos Delivopoulos, Alan F Murra. Controlled adhesion and growth of long term glial and neuronal cultures on Parylene-C. PloS one. vol 6. issue 9. 2012-02-10. PMID:21966523. |
we harvested glia and neurons from the sprague-dawley (p1-p7) rat hippocampus and utilized an established cell patterning technique in order to investigate cellular migration, over the course of 3 weeks. |
2012-02-10 |
2023-08-12 |
rat |
| Ji-Eun Kim, Seong-Il Yeo, Hea Jin Ryu, Chun Kee Chung, Min-Ju Kim, Tae-Cheon Kan. Changes in TWIK-related acid sensitive K+-1 and -3 channel expressions from neurons to glia in the hippocampus of temporal lobe epilepsy patients and experimental animal model. Neurochemical research. vol 36. issue 11. 2012-01-27. PMID:21710317. |
changes in twik-related acid sensitive k+-1 and -3 channel expressions from neurons to glia in the hippocampus of temporal lobe epilepsy patients and experimental animal model. |
2012-01-27 |
2023-08-12 |
human |
| Bunmi Ojo, Payam Rezaie, Paul L Gabbott, Thelma R Cowely, Nikolay I Medvedev, Marina A Lynch, Michael G Stewar. A neural cell adhesion molecule-derived peptide, FGL, attenuates glial cell activation in the aged hippocampus. Experimental neurology. vol 232. issue 2. 2011-12-20. PMID:21978973. |
a neural cell adhesion molecule-derived peptide, fgl, attenuates glial cell activation in the aged hippocampus. |
2011-12-20 |
2023-08-12 |
rat |
| Xue-Zhao Cao, Hong Ma, Jun-Ke Wang, Fang Liu, Bing-Yang Wu, A-Yong Tian, Ling-Ling Wang, Wen-Fei Ta. Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 8. 2011-11-14. PMID:20691747. |
the authors of this study investigated the expression of central cytokines il-1β, il-6 and tnf-α and hippocampal glial cell activation in aged and adult rats following partial hepatectomy. |
2011-11-14 |
2023-08-12 |
rat |
| Xue-Zhao Cao, Hong Ma, Jun-Ke Wang, Fang Liu, Bing-Yang Wu, A-Yong Tian, Ling-Ling Wang, Wen-Fei Ta. Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 8. 2011-11-14. PMID:20691747. |
hippocampal pro-inflammatory cytokines il-1β, il-6 and tnf-α and glial cell activation markers glial fibrillary acidic protein (gfap) and s100β were measured at each time point; cd200 and cd200r were also measured to explore potential mechanisms of glial cell activation. |
2011-11-14 |
2023-08-12 |
rat |
| Xue-Zhao Cao, Hong Ma, Jun-Ke Wang, Fang Liu, Bing-Yang Wu, A-Yong Tian, Ling-Ling Wang, Wen-Fei Ta. Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 8. 2011-11-14. PMID:20691747. |
immunohistochemistry assay further showed more hippocampal glial cell activation in aged rats compared to that in adults. |
2011-11-14 |
2023-08-12 |
rat |
| Xue-Zhao Cao, Hong Ma, Jun-Ke Wang, Fang Liu, Bing-Yang Wu, A-Yong Tian, Ling-Ling Wang, Wen-Fei Ta. Postoperative cognitive deficits and neuroinflammation in the hippocampus triggered by surgical trauma are exacerbated in aged rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 8. 2011-11-14. PMID:20691747. |
hippocampal pro-inflammatory cytokines and glial cell activation might mediate trauma-induced pocd. |
2011-11-14 |
2023-08-12 |
rat |
| Heyan Zhao, Guohua Jin, Meiling Tian, Haoming Li, Xinhua Zhan. Extract of deafferented hippocampus promotes in vitro radial glial cell differentiation into neurons. Neuroscience letters. vol 498. issue 1. 2011-11-07. PMID:21570447. |
extract of deafferented hippocampus promotes in vitro radial glial cell differentiation into neurons. |
2011-11-07 |
2023-08-12 |
rat |
| Xiaoquan Wang, Zhenghua Hou, Yonggui Yuan, Gang Hou, Yang Liu, Hailin Li, Zhijun Zhan. Association study between plasma GDNF and cognitive function in late-onset depression. Journal of affective disorders. vol 132. issue 3. 2011-10-24. PMID:21524799. |
the glial cell line-derived neurotrophic factor (gdnf) is a neurotrophic factor from the transforming growth factor-β-family, which plays a role in the development and function of hippocampal cells. |
2011-10-24 |
2023-08-12 |
Not clear |
| Linda Jansons Locht, Mie Ø Pedersen, Sara Markholt, Bo Martin Bibby, Agnete Larsen, Milena Penkowa, Meredin Stoltenberg, Jørgen Rungb. Metallic silver fragments cause massive tissue loss in the mouse brain. Basic & clinical pharmacology & toxicology. vol 109. issue 1. 2011-10-07. PMID:21205224. |
autometallographic silver enhancement showed silver uptake in lysosomes of glia cells and neurons in the ipsilateral cortex and hippocampus alongside a minor uptake on the contralateral side. |
2011-10-07 |
2023-08-12 |
mouse |
| Helena Pivonkova, Jana Benesova, Olena Butenko, Alexandr Chvatal, Miroslava Anderov. Impact of global cerebral ischemia on K+ channel expression and membrane properties of glial cells in the rat hippocampus. Neurochemistry international. vol 57. issue 7. 2011-09-07. PMID:20833221. |
since the changes in k(+) currents in astrocytes and ng2 glia that accompany glial scar formation might influence tissue outcome by altering k(+) ion homeostasis, we aimed to characterize the changes in k(+) currents in hippocampal astrocytes and ng2 glia during an extended time window of reperfusion after ischemic injury. |
2011-09-07 |
2023-08-12 |
rat |
| Helena Pivonkova, Jana Benesova, Olena Butenko, Alexandr Chvatal, Miroslava Anderov. Impact of global cerebral ischemia on K+ channel expression and membrane properties of glial cells in the rat hippocampus. Neurochemistry international. vol 57. issue 7. 2011-09-07. PMID:20833221. |
using the patch-clamp technique, we investigated the membrane properties of hippocampal astrocytes and ng2 glia in situ 2 hours, 6 hours, 1 day, 3 days, 7 days or 5 weeks after ischemia. |
2011-09-07 |
2023-08-12 |
rat |