Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Stephen C Canno. Epilepsy channelopathies go neddy: stabilizing NaV1.1 channels by neddylation. The Journal of clinical investigation. vol 131. issue 8. 2021-09-20. PMID:33855971. |
pursuing the possibility that this phenotype is also caused by loss of nav1.1, chen, luo, gao, and colleagues show that interneuron excitability and gaba release are impaired, nav1.1 degradation rate is increased with a commensurate decrease of nav1.1 protein, and nav1.1 is a substrate for neddylation. |
2021-09-20 |
2023-08-13 |
mouse |
Lydia Lebenheim, Sam A Booker, Christian Derst, Torsten Weiss, Franziska Wagner, Clemens Gruber, Imre Vida, Daniel S Zahm, Rüdiger W Ve. A novel giant non-cholinergic striatal interneuron restricted to the ventrolateral striatum coexpresses Kv3.3 potassium channel, parvalbumin, and the vesicular GABA transporter. Molecular psychiatry. 2021-08-12. PMID:33190145. |
a novel giant non-cholinergic striatal interneuron restricted to the ventrolateral striatum coexpresses kv3.3 potassium channel, parvalbumin, and the vesicular gaba transporter. |
2021-08-12 |
2023-08-13 |
Not clear |
N Forte, F Binda, A Contestabile, F Benfenati, P Baldell. Synapsin I Synchronizes GABA Release in Distinct Interneuron Subpopulations. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-09. PMID:31504258. |
synapsin i synchronizes gaba release in distinct interneuron subpopulations. |
2021-06-09 |
2023-08-13 |
Not clear |
N Forte, F Binda, A Contestabile, F Benfenati, P Baldell. Synapsin I Synchronizes GABA Release in Distinct Interneuron Subpopulations. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-09. PMID:31504258. |
the results demonstrate that syni is differentially expressed in interneuron subpopulations, where it boosts synchronous and limits asynchronous gaba release. |
2021-06-09 |
2023-08-13 |
Not clear |
Federico E Turkheimer, Erik D Fagerholm, Miriam Vignando, Jessica Dafflon, Pedro F Da Costa, Paola Dazzan, Robert Leec. A GABA Interneuron Deficit Model of the Art of Vincent van Gogh. Frontiers in psychiatry. vol 11. 2021-05-26. PMID:32754073. |
a gaba interneuron deficit model of the art of vincent van gogh. |
2021-05-26 |
2023-08-13 |
Not clear |
Keita Satoh, Emi Kiyokage, Satoshi Ichikawa, Kazunori Toid. Variations in GABA immunoreactivity among granule cells of the mouse olfactory bulb, as revealed by high-voltage electron microscopy. Neuroscience letters. vol 738. 2021-05-17. PMID:32947006. |
consequently, our results clearly show variations in the gaba immunoreactivity among gcl interneurons, which suggested heterogeneity in the amount of gaba present in each interneuron and reflected the possibility that different amounts of neuroactive substances may be associated with different functions for the various gabaergic interneuron groups. |
2021-05-17 |
2023-08-13 |
mouse |
Keita Satoh, Emi Kiyokage, Satoshi Ichikawa, Kazunori Toid. Variations in GABA immunoreactivity among granule cells of the mouse olfactory bulb, as revealed by high-voltage electron microscopy. Neuroscience letters. vol 738. 2021-05-17. PMID:32947006. |
variations in gaba immunoreactivity could be a novel criterion for classifying interneuron subpopulations. |
2021-05-17 |
2023-08-13 |
mouse |
Tiffany Hong, Carmen Falcone, Brett Dufour, Sarwat Amina, Rosalia Perez Castro, Jade Regalado, Weston Pearson, Stephen C Noctor, Verónica Martínez-Cerdeñ. GABA Neuroscience. vol 437. 2021-05-14. PMID:32335215. |
through human postmortem tissue analysis, we previously found a significant decrease in the number of a gamma-aminobutyric acid (gaba)ergic interneuron subtype, the chandelier (ch) cell, in the prefrontal cortex of subjects with autism. |
2021-05-14 |
2023-08-13 |
human |
Farhan Augustine, Shreenath Rajendran, Harvey S Singe. Cortical endogenous opioids and their role in facilitating repetitive behaviors in deer mice. Behavioural brain research. vol 379. 2021-04-30. PMID:31676208. |
one postulated cortical mechanism, supported by our findings, is an opioid effect on cortical interneuron gaba release and a consequent effect on glutamatergic cortical pyramidal cells. |
2021-04-30 |
2023-08-13 |
mouse |
Hyowon Chung, Kyerl Park, Hyun Jae Jang, Michael M Kohl, Jeehyun Kwa. Dissociation of somatostatin and parvalbumin interneurons circuit dysfunctions underlying hippocampal theta and gamma oscillations impaired by amyloid β oligomers in vivo. Brain structure & function. vol 225. issue 3. 2021-01-08. PMID:32107637. |
furthermore, analyses of the stimulus-response curve, paired-pulse ratio, and short-term plasticity of sst and pv interneuron-evoked ipscs ex vivo showed that aβo increased the initial gaba release probability to depress sst/pv interneuron's inhibitory input to ca1 pc selectively at theta and gamma frequencies, respectively. |
2021-01-08 |
2023-08-13 |
mouse |
Jennifer Larimore, Stephanie A Zlatic, Miranda Arnold, Kaela S Singleton, Rebecca Cross, Hannah Rudolph, Martha V Bruegge, Andrea Sweetman, Cecilia Garza, Eli Whisnant, Victor Faunde. Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus. Frontiers in genetics. vol 8. 2020-10-01. PMID:28344592. |
the neurodevelopmental factor dysbindin is required for synapse function and gaba interneuron development. |
2020-10-01 |
2023-08-13 |
mouse |
Manoela V Fogaça, Ronald S Duma. Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:30914923. |
mdd patients and chronically stressed animals show a reduction in gaba and gad67 levels in the brain, decreased expression of gabaergic interneuron markers, and alterations in gaba |
2020-10-01 |
2023-08-13 |
Not clear |
Junxiu Liu, Liam McDaid, Alfonso Araque, John Wade, Jim Harkin, Shvan Karim, David C Henshall, Niamh M C Connolly, Anju P Johnson, Andy M Tyrrell, Jon Timmis, Alan G Millard, James Hilder, David M Hallida. GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31396055. |
this paper presents a biophysical model that captures the interaction between an astrocyte cell, a gaba interneuron and pre/postsynaptic neurons. |
2020-10-01 |
2023-08-13 |
Not clear |
Junxiu Liu, Liam McDaid, Alfonso Araque, John Wade, Jim Harkin, Shvan Karim, David C Henshall, Niamh M C Connolly, Anju P Johnson, Andy M Tyrrell, Jon Timmis, Alan G Millard, James Hilder, David M Hallida. GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31396055. |
specifically, gaba released from a gaba interneuron triggers in astrocytes the release of calcium ( |
2020-10-01 |
2023-08-13 |
Not clear |
Mary-Anne B MacKay, John W Paylor, James T F Wong, Ian R Winship, Glen B Baker, Serdar M Dursu. Multidimensional Connectomics and Treatment-Resistant Schizophrenia: Linking Phenotypic Circuits to Targeted Therapeutics. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30425662. |
clinical studies that have used a variety of glutamate receptor and gaba interneuron modulators, nitric oxide-based therapies and a variety of other strategies as augmenting treatments with antipsychotic drugs are included. |
2020-09-30 |
2023-08-13 |
Not clear |
Ping Su, Terence K Y Lai, Frankie H F Lee, Andrew R Abela, Paul J Fletcher, Fang Li. Disruption of SynGAP-dopamine D1 receptor complexes alters actin and microtubule dynamics and impairs GABAergic interneuron migration. Science signaling. vol 12. issue 593. 2020-08-14. PMID:31387938. |
disruption of γ-aminobutyric acid (gaba)-ergic interneuron migration is implicated in various neurodevelopmental disorders, including autism spectrum disorder and schizophrenia. |
2020-08-14 |
2023-08-13 |
mouse |
Matthew J Girgenti, Eric S Wohleb, Sameet Mehta, Sriparna Ghosal, Manoela V Fogaca, Ronald S Duma. Prefrontal cortex interneurons display dynamic sex-specific stress-induced transcriptomes. Translational psychiatry. vol 9. issue 1. 2020-08-05. PMID:31712551. |
here, we analyze the transcriptional profiles and the effects of chronic stress in males vs. females on gaba interneuron subtypes in the pfc. |
2020-08-05 |
2023-08-13 |
mouse |
Ramon Pla, Amelia Stanco, MacKenzie A Howard, Anna N Rubin, Daniel Vogt, Niall Mortimer, Inma Cobos, Gregory Brian Potter, Susan Lindtner, James D Price, Alex S Nord, Axel Visel, Christoph E Schreiner, Scott C Baraban, David H Rowitch, John L R Rubenstei. Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 11. 2019-12-20. PMID:29028947. |
dlx1 and dlx2 promote interneuron gaba synthesis, synaptogenesis, and dendritogenesis. |
2019-12-20 |
2023-08-13 |
Not clear |
Marianna K Keaveney, Hua-An Tseng, Tina L Ta, Howard J Gritton, Heng-Ye Man, Xue Ha. A MicroRNA-Based Gene-Targeting Tool for Virally Labeling Interneurons in the Rodent Cortex. Cell reports. vol 24. issue 2. 2019-11-07. PMID:29996091. |
our interneuron-targeting, microrna-guided neuron tag, "gaba magnet," achieves >95% interneuron selective labeling in the mouse cortex, including in a murine model of autism and also some preferential labeling of interneurons in the rat brain. |
2019-11-07 |
2023-08-13 |
mouse |
Karri Lamsa, Petrina La. Long-term plasticity of hippocampal interneurons during in vivo memory processes. Current opinion in neurobiology. vol 54. 2019-08-22. PMID:30195105. |
recent experiments in anesthetized, as well as in freely moving animals, demonstrate that learning-related hippocampal activities are associated with persistent changes in gabaergic interneuron firing rates and alterations in protein expression levels regulating gaba release. |
2019-08-22 |
2023-08-13 |
Not clear |