| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Frithjof Lohmann, Marlies Sachs, Tobias N Meyer, Henning Sievert, Maja T Lindenmeyer, Thorsten Wiech, Clemens D Cohen, Stefan Balabanov, R A K Stahl, Catherine Meyer-Schwesinge. UCH-L1 induces podocyte hypertrophy in membranous nephropathy by protein accumulation. Biochimica et biophysica acta. vol 1842. issue 7. 2014-07-24. PMID:24583340. |
functionally, inhibition of uch-l1 activity and knockdown or inhibition of uch-l1 attenuated podocyte hypertrophy by decreasing the total protein content in isolated glomeruli and in cultured podocytes. |
2014-07-24 |
2023-08-12 |
human |
| Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Jung Hoon Choi, Woosuk Kim, Hyo Young Jung, Moo-Ho Won, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoo. Effects of treadmill exercise on neural stem cells, cell proliferation, and neuroblast differentiation in the subgranular zone of the dentate gyrus in cyclooxygenase-2 knockout mice. Neurochemical research. vol 38. issue 12. 2014-07-21. PMID:24150751. |
loss of cox-2 expression in the knockout mice was confirmed with two measures: (1) cox immunolabeling in the hippocampus, and (2) the identification of abnormal kidney development using hematoxylin and eosin staining, including subcapsular glomerular hypoplasia and hypertrophy of the deeper cortical glomeruli. |
2014-07-21 |
2023-08-12 |
mouse |
| Johanna Guzman, Alexandra N Jauregui, Sandra Merscher-Gomez, Dony Maiguel, Cristina Muresan, Alla Mitrofanova, Ana Diez-Sampedro, Joel Szust, Tae-Hyun Yoo, Rodrigo Villarreal, Christopher Pedigo, R Damaris Molano, Kevin Johnson, Barbara Kahn, Bjoern Hartleben, Tobias B Huber, Jharna Saha, George W Burke, E Dale Abel, Frank C Brosius, Alessia Fornon. Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy. Diabetes. vol 63. issue 2. 2014-03-28. PMID:24101677. |
glomeruli from g4 ko mice were protected from diabetes-induced hypertrophy, mesangial expansion, and albuminuria and failed to activate the mammalian target of rapamycin (mtor) pathway. |
2014-03-28 |
2023-08-12 |
mouse |
| Ho Sung Lee, Bum Keun Kim, Yunsung Nam, Uy Dong Sohn, Eon Sub Park, Soon Auck Hong, Jong Hyuk Lee, Yoon Hee Chung, Ji Hoon Jeon. Protective role of phosphatidylcholine against cisplatin-induced renal toxicity and oxidative stress in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 58. 2014-03-05. PMID:23684996. |
pc also decreased tubular degeneration and hypertrophy of glomeruli. |
2014-03-05 |
2023-08-12 |
rat |
| Yi Lin, Makoto Kuro-o, Zhongjie Su. Genetic deficiency of anti-aging gene klotho exacerbates early nephropathy in STZ-induced diabetes in male mice. Endocrinology. vol 154. issue 10. 2013-11-25. PMID:23928372. |
klotho deficiency in kl(+/-) mutant mice exacerbated stz-induced increases in urine albumin, blood urea nitrogen, expansion of mesangial matrix in renal glomeruli, and kidney hypertrophy, suggesting a protective role of klotho in kidney function and structure. |
2013-11-25 |
2023-08-12 |
mouse |
| Ashish K Mishra, Banalata Mohant. Acute toxicity impacts of hexavalent chromium on behavior and histopathology of gill, kidney and liver of the freshwater fish, Channa punctatus (Bloch). Environmental toxicology and pharmacology. vol 26. issue 2. 2012-10-02. PMID:21783901. |
hypertrophy of epithelial cells of renal tubules with reduced lumens, atrophy of the renal tubules, glomeruli contraction in the bowman's capsules and necrosis of haematopoietic tissues were observed in the trunk kidney of exposed fish. |
2012-10-02 |
2023-08-12 |
Not clear |
| b' Vesna R Stojanovi\\xc4\\x87, Ivan D Jovanovi\\xc4\\x87, Sladjana Z Ugrenovi\\xc4\\x87, Ljiljana P Vasovi\\xc4\\x87, Vladimir S \\xc5\\xbdivkovi\\xc4\\x87, Miodrag V Joci\\xc4\\x87, Braca K Kundali\\xc4\\x87, Miljana N Pavlovi\\xc4\\x8. Morphometric analysis of nonsclerosed Glomeruli size and connective tissue content during the aging process. TheScientificWorldJournal. vol 2012. 2012-09-27. PMID:22654637.' |
consequently, majority of remained nonsclerosed glomeruli become hypertrophic and some of them sclerotic, too. |
2012-09-27 |
2023-08-12 |
human |
| b' Vesna R Stojanovi\\xc4\\x87, Ivan D Jovanovi\\xc4\\x87, Sladjana Z Ugrenovi\\xc4\\x87, Ljiljana P Vasovi\\xc4\\x87, Vladimir S \\xc5\\xbdivkovi\\xc4\\x87, Miodrag V Joci\\xc4\\x87, Braca K Kundali\\xc4\\x87, Miljana N Pavlovi\\xc4\\x8. Morphometric analysis of nonsclerosed Glomeruli size and connective tissue content during the aging process. TheScientificWorldJournal. vol 2012. 2012-09-27. PMID:22654637.' |
the aim of this study was to quantify the size and connective tissue content of nonsclerosed glomeruli and to evaluate the percentage of hypertrophic ones in examined human cases during the aging. |
2012-09-27 |
2023-08-12 |
human |
| b' Vesna R Stojanovi\\xc4\\x87, Ivan D Jovanovi\\xc4\\x87, Sladjana Z Ugrenovi\\xc4\\x87, Ljiljana P Vasovi\\xc4\\x87, Vladimir S \\xc5\\xbdivkovi\\xc4\\x87, Miodrag V Joci\\xc4\\x87, Braca K Kundali\\xc4\\x87, Miljana N Pavlovi\\xc4\\x8. Morphometric analysis of nonsclerosed Glomeruli size and connective tissue content during the aging process. TheScientificWorldJournal. vol 2012. 2012-09-27. PMID:22654637.' |
such glomeruli might be considered as hypertrophic. |
2012-09-27 |
2023-08-12 |
human |
| Michael Hultströ. Development of structural kidney damage in spontaneously hypertensive rats. Journal of hypertension. vol 30. issue 6. 2012-08-31. PMID:22469837. |
progressive arteriolar media hypertrophy then leads to the collapse of some glomeruli followed by tubular atrophy. |
2012-08-31 |
2023-08-12 |
human |
| Kuan-Hsing Chen, Cheng-Chieh Hung, Hsiang-Hao Hsu, Yu-Hong Jing, Chih-Wei Yang, Jan-Kan Che. Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats. Chemico-biological interactions. vol 190. issue 1. 2011-05-23. PMID:21300041. |
urinary albumin excretion, glomerular hypertrophy and expressions of fibronectin, collagen iv, and tgf-β in the glomeruli were alleviated in rsv-treated dm rats, but not in untreated dm rats. |
2011-05-23 |
2023-08-12 |
rat |
| Motofumi Sasaki, Kenichi Shikata, Shinichi Okada, Satoshi Miyamoto, Shingo Nishishita, Hitomi Usui Kataoka, Chikage Sato, Jun Wada, Daisuke Ogawa, Hirofumi Makin. The macrophage is a key factor in renal injuries caused by glomerular hyperfiltration. Acta medica Okayama. vol 65. issue 2. 2011-05-19. PMID:21519365. |
the 5/6 nephrectomized mice showed glomerular hypertrophy and an increase in the extracellular matrix in the glomeruli. |
2011-05-19 |
2023-08-12 |
mouse |
| Takaaki Ishida, Keiji Shimazu, Kouji Takaori, Keita Mori, Soushi Yorifuji, Kensuke Nishiguchi, Eriko Eguchi, Masao Koshikawa, Atsuo Tanaka, Takashi Kuwahar. [Case of a focal segmental glomerulosclerosis collapsing variant associated with a hypertrophic column of Bertin]. Nihon Jinzo Gakkai shi. vol 53. issue 1. 2011-05-05. PMID:21370578. |
the results showed a segmental sclerotic lesion associated with hypertrophy and proliferation of podocytes in several glomeruli, hence we diagnosed a focal segmental glomerulosclerosis collapsing variant. |
2011-05-05 |
2023-08-12 |
Not clear |
| Jorge Vega, Francisco Javier Guarda, Helmuth Goecke, Gonzalo P Ménde. Complete remission of non-HIV collapsing glomerulopathy with deflazacort and lisinopril in an adult patient. Clinical and experimental nephrology. vol 14. issue 4. 2010-11-22. PMID:20428916. |
its pathological features include collapsed glomeruli, podocyte hypertrophy and hyperplasia, and pseudocrescents. |
2010-11-22 |
2023-08-12 |
Not clear |
| Nirmalya Dey, Nandini Ghosh-Choudhury, Falguni Das, Xiaonan Li, Balachandar Venkatesan, Jeffrey L Barnes, Balakuntalam S Kasinath, Goutam Ghosh Choudhur. PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy. Journal of cellular physiology. vol 225. issue 1. 2010-09-14. PMID:20629086. |
streptozotocin-induced diabetic renal hypertrophy was associated with phosphorylation of pras40 in the cortex and glomeruli. |
2010-09-14 |
2023-08-12 |
rat |
| A A Ghoreye. A STUDY OF THE CIRCULATION OF THE KIDNEYS FOLLOWING LIGATION OF ONE URETER. The Journal of experimental medicine. vol 20. issue 2. 2010-06-22. PMID:19867813. |
at the end of twenty days from the time of ligation there is also a marked hypertrophy of the control kidney, the glomeruli showing an average increase in size of twenty-five microns. |
2010-06-22 |
2023-08-12 |
Not clear |
| Supap Saenphet, Worawut Thaworn, Kanokporn Saenphe. Histopathological alterations of the gills, liver and kidneys in Anabas testudineus (Bloch) fish living in an unused lignite mine, Li District, Lamphun Province, Thailand. The Southeast Asian journal of tropical medicine and public health. vol 40. issue 5. 2009-11-24. PMID:19842397. |
in addition, hypertrophy of the epithelial cells of the renal tubules with reduced lumens, aneurisms of the renal tubules, and contractions of the glomeruli in the bowman's capsule were observed. |
2009-11-24 |
2023-08-12 |
Not clear |
| Masahito Ozeki, Hajime Nagasu, Minoru Satoh, Tamehachi Namikoshi, Yoshisuke Haruna, Naruya Tomita, Tamaki Sasaki, Naoki Kashihar. Reactive oxygen species mediate compensatory glomerular hypertrophy in rat uninephrectomized kidney. The journal of physiological sciences : JPS. vol 59. issue 5. 2009-11-17. PMID:19593678. |
levels of phospho-akt and phospho-ribosomal protein s6, which are critical for cell growth and hypertrophy, were markedly increased in the glomeruli of the nx, while tempol treatment almost abolished the activation of these proteins. |
2009-11-17 |
2023-08-12 |
rat |
| Masahito Ozeki, Hajime Nagasu, Minoru Satoh, Tamehachi Namikoshi, Yoshisuke Haruna, Naruya Tomita, Tamaki Sasaki, Naoki Kashihar. Reactive oxygen species mediate compensatory glomerular hypertrophy in rat uninephrectomized kidney. The journal of physiological sciences : JPS. vol 59. issue 5. 2009-11-17. PMID:19593678. |
these results suggest that ros have important roles in compensatory hypertrophy in glomeruli. |
2009-11-17 |
2023-08-12 |
rat |
| Mariana Baserga, Allyson L Bares, Merica A Hale, Christopher W Callaway, Robert A McKnight, Pascale H Lane, Robert H Lan. Uteroplacental insufficiency affects kidney VEGF expression in a model of IUGR with compensatory glomerular hypertrophy and hypertension. Early human development. vol 85. issue 6. 2009-07-23. PMID:19188030. |
low nephron endowment secondary to intrauterine growth restriction (iugr) results in compensatory hypertrophy of the remaining glomeruli, which in turn is associated with hypertension. |
2009-07-23 |
2023-08-12 |
rat |