| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| María Ramos, Beatriz Goñi-Allo, Norberto Aguirr. Ibotenic acid lesions of the medial prefrontal cortex block the development and expression of 3,4-methylenedioxymethamphetamine-induced behavioral sensitization in rats. Behavioural brain research. vol 160. issue 2. 2005-07-15. PMID:15863226. |
more specifically the glutamatergic input from the medial prefrontal cortex (mpfc) to the vta and the nac appears to be involved in behavioral sensitization processes. |
2005-07-15 |
2023-08-12 |
rat |
| Ipe Ninan, Rex Y Wan. Modulation of the ability of clozapine to facilitate NMDA- and electrically evoked responses in pyramidal cells of the rat medial prefrontal cortex by dopamine: pharmacological evidence. The European journal of neuroscience. vol 17. issue 6. 2003-06-27. PMID:12670320. |
when rats were pretreated with reserpine (which blocks storage of biogenic amines) and alpha-methyl para-tyrosine (ampt, which inhibits tyrosine hydroxylase, the rate-limiting enzyme for the da synthesis), the ability of clozapine to augment glutamatergic transmission in pyramidal cells of the medial prefrontal cortex (mpfc) was totally abolished. |
2003-06-27 |
2023-08-12 |
rat |
| Hyun S Lee, Myung A Kim, Rita J Valentino, Barry D Waterhous. Glutamatergic afferent projections to the dorsal raphe nucleus of the rat. Brain research. vol 963. issue 1-2. 2003-04-28. PMID:12560111. |
phaseolus vulgaris leucoagglutinin anterograde tracing studies confirmed that the medial prefrontal cortex provides the major afferent input to each subdivision of the dr. double-labeling studies combining wg tracing and glutamate immunostaining indicated that the medial prefrontal cortex, various hypothalamic nuclei including perifornical, lateral, and arcuate nuclei, and several medullary regions such as lateral and medial parabrachial nuclei, and laterodorsal tegmental nucleus provide the major glutamatergic input to each subregion of the dr. |
2003-04-28 |
2023-08-12 |
rat |
| S Otani, H Daniel, M Takita, F Crépe. Long-term depression induced by postsynaptic group II metabotropic glutamate receptors linked to phospholipase C and intracellular calcium rises in rat prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978820. |
we have previously shown (otani et al., 1999b) that bath application of (2s,2'r,3'r)-2-(2',3'-dicarboxycyclopropyl)glycine (dcg iv), the agonist of group ii metabotropic glutamate receptors (mglurs), induces postsynaptic ca2+-dependent long-term depression (ltd) of layer i-ii to layer v pyramidal neuron glutamatergic synapses of rat medial prefrontal cortex. |
2002-05-20 |
2023-08-12 |
rat |
| W-K Park, A A Bari, A R Jey, S M Anderson, R D Spealman, J K Rowlett, R C Pierc. Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923456. |
we used an animal model of cocaine relapse to determine the role of the glutamatergic pathway from the medial prefrontal cortex (mpfc) to the nucleus accumbens in the reinstatement of cocaine-seeking behavior after a cocaine priming injection. |
2002-04-08 |
2023-08-12 |
human |
| G J Marek, R A Wright, J C Gewirtz, D D Schoep. A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex. Neuroscience. vol 105. issue 2. 2001-12-07. PMID:11672605. |
the purpose of the present study was to determine the source of subcortical glutamatergic afferents, which would project widely throughout the anterior-posterior axis of the rat brain to the apical dendrites of layer v pyramidal cells of the medial prefrontal cortex, from which serotonin induces transmitter release via activation of 5-ht(2a) receptors. |
2001-12-07 |
2023-08-12 |
rat |
| G G Nomikos, B Schilström, B E Hildebrand, G Panagis, J Grenhoff, T H Svensso. Role of alpha7 nicotinic receptors in nicotine dependence and implications for psychiatric illness. Behavioural brain research. vol 113. issue 1-2. 2001-01-03. PMID:10942036. |
based on the data reviewed in the present study, it is suggested that nicotine by stimulating presynaptic alpha7 nicotinic receptors within the vta, that are probably localized on glutamatergic afferents from the medial prefrontal cortex, produces sequentially an increase in glutamate concentrations, stimulation of nmda receptors found on dopamine (da)-containing neurons in the vta, enhanced firing activity of vta-da neurons, augmented da release in the nerve terminal regions, and enhanced c-fos expression in the dopaminergic projection areas through activation of d1-da receptors. |
2001-01-03 |
2023-08-12 |
Not clear |
| M Cador, Y Bjijou, S Cailhol, L Stinu. D-amphetamine-induced behavioral sensitization: implication of a glutamatergic medial prefrontal cortex-ventral tegmental area innervation. Neuroscience. vol 94. issue 3. 1999-12-17. PMID:10579562. |
these experiments confirmed (i) that the ventral tegmental area, where dopaminergic cell bodies are located, is a critical site for the induction of behavioral sensitization, (ii) that this process implicates the glutamatergic transmission in the ventral tegmental area, and (iii) that the medial prefrontal cortex is crucially implicated merely because of its direct glutamatergic inputs on to ventral tegmental area neurons. |
1999-12-17 |
2023-08-12 |
Not clear |
| M Cador, Y Bjijou, S Cailhol, L Stinu. D-amphetamine-induced behavioral sensitization: implication of a glutamatergic medial prefrontal cortex-ventral tegmental area innervation. Neuroscience. vol 94. issue 3. 1999-12-17. PMID:10579562. |
together, these results reinforce the view that the behavioral sensitization to amphetamine implicates not only the mesoaccumbens dopaminergic neurons, but also other structures of the mesocorticolimbic system, such as the medial prefrontal cortex and more specifically its glutamatergic component. |
1999-12-17 |
2023-08-12 |
Not clear |
| S Jones, J A Kaue. Amphetamine depresses excitatory synaptic transmission via serotonin receptors in the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 22. 1999-12-02. PMID:10559387. |
a major excitatory projection to vta neurons originates in the medial prefrontal cortex, and several lines of evidence suggest that glutamatergic synapses on vta neurons are activated and modified during exposure to psychostimulant drugs. |
1999-12-02 |
2023-08-12 |
Not clear |
| M J Christie, L B James, P M Bear. An excitatory amino acid projection from rat prefrontal cortex to periaqueductal gray. Brain research bulletin. vol 16. issue 1. 1986-05-05. PMID:2869823. |
these results suggest the presence of glutamatergic and/or aspartatergic projections from medial prefrontal cortex to periaqueductal grey matter. |
1986-05-05 |
2023-08-11 |
rat |
| C J Carte. Topographical distribution of possible glutamatergic pathways from the frontal cortex to the striatum and substantia nigra in rats. Neuropharmacology. vol 21. issue 5. 1982-10-21. PMID:7110527. |
the topographical distribution of putative glutamatergic projections from the frontal cortex to the striatum and substantia nigra has been examined by measuring the high-affinity uptake of [14c]glutamate in synaptosomal preparations from rat anterior or posterior striatum and substantia nigra after a series of focal kainic acid lesions of the medial prefrontal cortex. |
1982-10-21 |
2023-08-12 |
rat |