All Relations between glutamatergic and medial prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. moreover, in the context of attenuating anxiety-like behaviors through zl006 treatment, we observe a reduction in closed head injury-induced astrocyte engulfment, which may correlate with the observed decrease in dendritic spine density of medial prefrontal cortex glutamatergic neurons. 2024-06-08 2024-06-11 Not clear
Rui Sun, Meng-Yu Tang, Dan Yang, Yan-Yi Zhang, Yi-Heng Xu, Yong Qiao, Bin Yu, Shu-Xia Cao, Hao Wang, Hui-Qian Huang, Hong Zhang, Xiao-Ming Li, Hong Lia. C3aR in the medial prefrontal cortex modulates the susceptibility to LPS-induced depressive-like behaviors through glutamatergic neuronal excitability. Progress in neurobiology. 2024-04-19. PMID:38641040. c3ar in the medial prefrontal cortex modulates the susceptibility to lps-induced depressive-like behaviors through glutamatergic neuronal excitability. 2024-04-19 2024-04-22 mouse
Brenna C Duffy, Kirsten M King, Binod Nepal, Michael R Nonnemacher, Sandhya Kortager. Acute Administration of HIV-1 Tat Protein Drives Glutamatergic Alterations in a Rodent Model of HIV-Associated Neurocognitive Disorders. Molecular neurobiology. 2024-03-22. PMID:38514527. to identify changes in regional glutamatergic circuitry underlying cognitive impairment, we injected recombinant tat86 or saline to medial prefrontal cortex (mpfc) of male sprague-dawley rats. 2024-03-22 2024-03-24 rat
Yehao Liu, Xiaoyu Zhou, Ke Xue, Ruiao Sun, Yan Tang, Chuanxi Tan. Reviving: restoring depression-like behaviour through glial cell-derived neurotrophic factor treatment in the medial prefrontal cortex. Journal of psychiatry & neuroscience : JPN. vol 49. issue 1. 2024-02-01. PMID:38302136. depression is a prevalent nonmotor symptom in parkinson disease and can greatly reduce the quality of life for patients; the dopamine receptors found in glutamatergic pyramidal cells in the medial prefrontal cortex (mpfc) play a role in regulating local field activity, which in turn affects behavioural and mood disorders. 2024-02-01 2024-02-04 mouse
Ji Hyeong Baek, Hyeongchan Park, Hyeju Kang, Rankyung Kim, Jae Soon Kang, Hyun Joon Ki. The Role of Glutamine Homeostasis in Emotional and Cognitive Functions. International journal of molecular sciences. vol 25. issue 2. 2024-01-27. PMID:38279303. recent findings indicated that a neuronal gln deficiency in the medial prefrontal cortex in rodents led to depressive behaviors and mild cognitive impairment along with lower glutamatergic neurotransmission. 2024-01-27 2024-01-29 Not clear
Jayapriya Chandrasekaran, Kevin K Caldwell, Jonathan L Brigma. Dynamic regulation of corticostriatal glutamatergic synaptic expression during reversal learning in male mice. Neurobiology of learning and memory. 2024-01-19. PMID:38242226. following training to well-established stages of discrimination and reversal learning on a touchscreen visual task, lateral orbitofrontal cortex (ofc), dorsal striatum (ds) as well as medial prefrontal cortex (mpfc), basolateral amygdala (bla) and piriform cortex (pir) were micro dissected from male mouse brain and the expression of glutamatergic receptor subunits in the synaptic fraction were measured via immunoblotting. 2024-01-19 2024-01-22 mouse
Nicholas Spitzer, Marta Pratelli, Anna Hakimi, Arth Thaker, Hui-Quan Li, Swetha Godavarth. Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits. Research square. 2024-01-03. PMID:38168375. we find that both phencyclidine and methamphetamine, despite differing in their targets in the brain, cause the same glutamatergic neurons in the medial prefrontal cortex to gain a gabaergic phenotype and decrease their expression of the vesicular glutamate transporter. 2024-01-03 2024-01-06 Not clear
Jiao-Zhao Yan, Guang-Xiang Li, Si-Rui Sun, Lin-Yu Cui, Yong-Yu Yin, Yun-Feng L. A critical step in antidepressants onset: Excitation of glutamatergic pyramidal neurons in rodents' medial prefrontal cortex. Progress in neuro-psychopharmacology & biological psychiatry. 2023-12-08. PMID:38065287. a critical step in antidepressants onset: excitation of glutamatergic pyramidal neurons in rodents' medial prefrontal cortex. 2023-12-08 2023-12-17 mouse
Jiao-Zhao Yan, Guang-Xiang Li, Si-Rui Sun, Lin-Yu Cui, Yong-Yu Yin, Yun-Feng L. A critical step in antidepressants onset: Excitation of glutamatergic pyramidal neurons in rodents' medial prefrontal cortex. Progress in neuro-psychopharmacology & biological psychiatry. 2023-12-08. PMID:38065287. we investigated the behavioral effects of five different antidepressants (differing in target, chemical structure, and rate of onset) and their effects on the firing activities of glutamatergic pyramidal neurons in the medial prefrontal cortex (mpfc) using the forced swimming test (fst) and electrophysiological techniques (in vivo). 2023-12-08 2023-12-17 mouse
Jean-Philippe Guilloux, Thi Mai Loan Nguyen, Alain M Gardie. [Ketamine: a neuropsychotropic drug with an innovative mechanism of action]. Biologie aujourd'hui. vol 217. issue 3-4. 2023-11-29. PMID:38018940. the glutamatergic pyramidal cells of the medial prefrontal cortex are primarily implicated in the therapeutic effects of ketamine. 2023-11-29 2023-12-07 Not clear
Stuart A Collins, Hannah E Stinson, Amanda Himes, Andrea Nestor-Kalinoski, Ipe Nina. Sex-specific modulation of the medial prefrontal cortex by glutamatergic median raphe neurons. Science advances. vol 9. issue 45. 2023-11-10. PMID:37948526. sex-specific modulation of the medial prefrontal cortex by glutamatergic median raphe neurons. 2023-11-10 2023-11-20 mouse
Stuart A Collins, Hannah E Stinson, Amanda Himes, Andrea Nestor-Kalinoski, Ipe Nina. Sex-specific modulation of the medial prefrontal cortex by glutamatergic median raphe neurons. Science advances. vol 9. issue 45. 2023-11-10. PMID:37948526. we investigated how glutamatergic median raphe nucleus (mrn) input modulates the medial prefrontal cortex (mpfc), a critical component of fear circuitry. 2023-11-10 2023-11-20 mouse
Qiang Shan, Xiaoli Lin, Xiaoxuan Yu, Wenye Guo, Yao Tia. Reduced activity of glutamatergic neurons in the prelimbic medial prefrontal cortex underlies the inherent aging-related physiological reduction in social dominance. The journals of gerontology. Series A, Biological sciences and medical sciences. 2023-09-14. PMID:37708075. reduced activity of glutamatergic neurons in the prelimbic medial prefrontal cortex underlies the inherent aging-related physiological reduction in social dominance. 2023-09-14 2023-10-07 mouse
Qiang Shan, Xiaoli Lin, Xiaoxuan Yu, Wenye Guo, Yao Tia. Reduced activity of glutamatergic neurons in the prelimbic medial prefrontal cortex underlies the inherent aging-related physiological reduction in social dominance. The journals of gerontology. Series A, Biological sciences and medical sciences. 2023-09-14. PMID:37708075. this study further identified an aging-related microscopic functional alteration, i.e., a reduction in the activity of glutamatergic pyramidal neurons in the prelimbic medial prefrontal cortex; and established that this reduction in neuronal activity serves as an intrinsic physiological mechanism underlying the macroscopic aging-related reduction in dominance. 2023-09-14 2023-10-07 mouse
Stuart A Collins, Hannah E Stinson, Amanda Himes, Andrea Nestor-Kalinoski, Ipe Nina. Sex-specific modulation of the medial prefrontal cortex by glutamatergic median raphe neurons. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693545. sex-specific modulation of the medial prefrontal cortex by glutamatergic median raphe neurons. 2023-09-11 2023-10-07 mouse
Stuart A Collins, Hannah E Stinson, Amanda Himes, Andrea Nestor-Kalinoski, Ipe Nina. Sex-specific modulation of the medial prefrontal cortex by glutamatergic median raphe neurons. bioRxiv : the preprint server for biology. 2023-09-11. PMID:37693545. the present study investigated how glutamatergic median raphe nucleus (mrn) input modulates the medial prefrontal cortex (mpfc), a critical component of fear circuitry. 2023-09-11 2023-10-07 mouse
Ji Hyeong Baek, Jae Soon Kang, Miyoung Song, Dong Kun Lee, Hyun Joon Ki. Glutamine Supplementation Preserves Glutamatergic Neuronal Activity in the Infralimbic Cortex, Which Delays the Onset of Mild Cognitive Impairment in 3×Tg-AD Female Mice. Nutrients. vol 15. issue 12. 2023-06-28. PMID:37375700. in this study, we evaluated the effects of gln on glutamatergic activity in the medial prefrontal cortex and the onset of cognitive impairment in a triple-transgenic alzheimer's disease mouse model (3×tg-ad). 2023-06-28 2023-08-14 mouse
Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. neuronal mapping demonstrates that oxt preferentially potentiates glutamate synapses of 5-ht neurons projecting to medial prefrontal cortex (mpfc) and depresses glutamatergic inputs to 5-ht neurons projecting to lateral habenula (lhb) and central amygdala (cea). 2023-05-30 2023-08-14 Not clear
Yujie Xiong, Beining Wang, Yunxia Shang, Huan Liu, Zihao Zhan, Qi Xu, Kai Wang, Zhi Zhang, Tingting Su. Glutamatergic neurons and GABAergic neurons of medial prefrontal cortex control hoarding-like behavior. Frontiers in neuroscience. vol 17. 2023-05-30. PMID:37250409. glutamatergic neurons and gabaergic neurons of medial prefrontal cortex control hoarding-like behavior. 2023-05-30 2023-08-14 mouse
Yujie Xiong, Beining Wang, Yunxia Shang, Huan Liu, Zihao Zhan, Qi Xu, Kai Wang, Zhi Zhang, Tingting Su. Glutamatergic neurons and GABAergic neurons of medial prefrontal cortex control hoarding-like behavior. Frontiers in neuroscience. vol 17. 2023-05-30. PMID:37250409. using viral infections and brain slice electrophysiology recordings, we found that increased glutamatergic neuronal activity and decreased gabaergic neuronal activity in medial prefrontal cortex (mpfc) accelerated the hoarding-like behavior in mice. 2023-05-30 2023-08-14 mouse