| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Franco-Villanueva, Neil C Ford, Rachel L Morano, Benjamin A Packard, Mark L Baccei, James P Herma. Time-dependent Actions of Corticosterone on Infralimbic Cortex Pyramidal Neurons of Adult Male Rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2025-03-18. PMID:40101963. |
the infralimbic medial prefrontal cortex (il-mpfc) modulates the switch between behavioral coping styles, and acute stress enhances glutamatergic neurotransmission on mpfc projection neurons. |
2025-03-18 |
2025-03-21 |
rat |
| Qiuying Zhao, Ze Fan, Yiwen Zhang, Jiaqi Li, Yuanyuan Zhu, Yiting Lin, Qingrong Ni, Xiaotong Shi, Ling Liu, Shengxi Wu, Jing Huan. Glutamatergic projections from the basolateral amygdala to medial prefrontal cortex contribute to acute itch sensation processing. The Journal of investigative dermatology. 2025-03-05. PMID:40043789. |
glutamatergic projections from the basolateral amygdala to medial prefrontal cortex contribute to acute itch sensation processing. |
2025-03-05 |
2025-03-08 |
Not clear |
| Lihua Chen, Tabita Kreko-Pierce, Stefanie L Cassoday, Lena Al-Harthi, Xiu-Ti H. Methamphetamine self-administration causes neuronal dysfunction in rat medial prefrontal cortex in a sex-specific and withdrawal time-dependent manner. Frontiers in pharmacology. vol 16. 2025-03-04. PMID:40028159. |
these cognitive deficits are associated with dysfunction of glutamatergic pyramidal neurons in the medial prefrontal cortex (mpfc), which regulates addiction and cognition. |
2025-03-04 |
2025-03-06 |
human |
| Xiaorong Zheng, Yuanjia Zheng, Zhe Zhai, Yiwen Chen, Yao Zhu, Guofan Qiu, Bokai Wang, Shuxin Wang, Yongjun Chen, Jinglan Ya. Electroacupuncture restores maternal separation-induced glutamatergic presynaptic deficits of the medial prefrontal cortex in adulthood. Neuroscience. 2025-02-24. PMID:39993668. |
electroacupuncture restores maternal separation-induced glutamatergic presynaptic deficits of the medial prefrontal cortex in adulthood. |
2025-02-24 |
2025-02-27 |
rat |
| Xiang Li, Xing Xu, Quying Feng, Ning Zhou, Yuhong He, Ying Liu, Haoqing Tai, Hee Young Kim, Yu Fan, Xiaowei Gua. Glutamatergic pathways from medial prefrontal cortex to paraventricular nucleus of thalamus contribute to the methamphetamine-induced conditioned place preference without affecting wakefulness. Theranostics. vol 15. issue 5. 2025-02-03. PMID:39897554. |
glutamatergic pathways from medial prefrontal cortex to paraventricular nucleus of thalamus contribute to the methamphetamine-induced conditioned place preference without affecting wakefulness. |
2025-02-03 |
2025-02-05 |
Not clear |
| Xiang Li, Xing Xu, Quying Feng, Ning Zhou, Yuhong He, Ying Liu, Haoqing Tai, Hee Young Kim, Yu Fan, Xiaowei Gua. Glutamatergic pathways from medial prefrontal cortex to paraventricular nucleus of thalamus contribute to the methamphetamine-induced conditioned place preference without affecting wakefulness. Theranostics. vol 15. issue 5. 2025-02-03. PMID:39897554. |
the goal of the current study is to explore the role of the pvt and the glutamatergic projections from medial prefrontal cortex (mpfc) to pvt in the reward process of meth. |
2025-02-03 |
2025-02-05 |
Not clear |
| Manoela V Fogaça, Fernanda Daher, Marina R Picciott. Effects of ketamine on GABAergic and glutamatergic activity in the mPFC: biphasic recruitment of GABA function in antidepressant-like responses. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-10-10. PMID:39390105. |
major depressive disorder (mdd) is associated with disruptions in glutamatergic and gabaergic activity in the medial prefrontal cortex (mpfc), leading to altered synaptic formation and function. |
2024-10-10 |
2024-10-13 |
mouse |
| Yinan Du, Yukui Zhao, Aozhuo Zhang, Zhiwei Li, Chunling Wei, Qiaohua Zheng, Yanning Qiao, Yihui Liu, Wei Ren, Jing Han, Zongpeng Sun, Weiping Hu, Zhiqiang Li. The Role of the Mu Opioid Receptors of the Medial Prefrontal Cortex in the Modulation of Analgesia Induced by Acute Restraint Stress in Male Mice. International journal of molecular sciences. vol 25. issue 18. 2024-09-28. PMID:39337262. |
in this study, we investigated the contributions of mors expressed on glutamatergic (morglut) and gabaergic (morgaba) neurons of the medial prefrontal cortex (mpfc), as well as the functional role and activity of neurons projecting from the mpfc to the periaqueductal gray (pag) region, in male mice. |
2024-09-28 |
2024-10-01 |
mouse |
| Marta Pratelli, Anna M Hakimi, Arth Thaker, Hyeonseok Jang, Hui-Quan Li, Swetha K Godavarthi, Byung Kook Lim, Nicholas C Spitze. Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits. Nature communications. vol 15. issue 1. 2024-09-26. PMID:39327428. |
we find that both phencyclidine and methamphetamine, despite differing in their targets in the brain, cause the same glutamatergic neurons in the medial prefrontal cortex of male mice to gain a gabaergic phenotype and decrease expression of their glutamatergic phenotype. |
2024-09-26 |
2024-09-29 |
mouse |
| Manoela V Fogaça, Fernanda Daher, Marina R Picciott. Effects of ketamine on GABAergic and glutamatergic activity in the mPFC: biphasic recruitment of GABA function in antidepressant-like responses. bioRxiv : the preprint server for biology. 2024-08-12. PMID:39131322. |
major depressive disorder (mdd) is associated with disruptions in glutamatergic and gabaergic activity in the medial prefrontal cortex (mpfc), leading to altered synaptic formation and function. |
2024-08-12 |
2024-08-14 |
Not clear |
| Reesha R Patel, Pauravi Gandhi, Kathryn Spencer, Nihal A Salem, Chloe M Erikson, Vittoria Borgonetti, Roman Vlkolinsky, Larry Rodriguez, Tali Nadav, Michal Bajo, Amanda J Roberts, R Dayne Mayfield, Marisa Robert. Functional and morphological adaptation of medial prefrontal corticotropin releasing factor receptor 1-expressing neurons in male mice following chronic ethanol exposure. Neurobiology of stress. vol 31. 2024-07-10. PMID:38983690. |
chronic ethanol dependence and withdrawal activate corticotropin releasing factor (crf)-containing gabaergic neurons in the medial prefrontal cortex (mpfc), which tightly regulate glutamatergic pyramidal neurons. |
2024-07-10 |
2024-07-12 |
mouse |
| Liang Zhao, Hui Ling Qu, Yan Zhang, Xin Wu, Qian Xin Ji, Zhuo Zhang, Dan L. ZL006 mitigates anxiety-like behaviors induced by closed head injury through modulation of the neural circuit from the medial prefrontal cortex to amygdala. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 6. 2024-06-08. PMID:38850218. |
moreover, in the context of attenuating anxiety-like behaviors through zl006 treatment, we observe a reduction in closed head injury-induced astrocyte engulfment, which may correlate with the observed decrease in dendritic spine density of medial prefrontal cortex glutamatergic neurons. |
2024-06-08 |
2024-06-11 |
Not clear |
| Rui Sun, Meng-Yu Tang, Dan Yang, Yan-Yi Zhang, Yi-Heng Xu, Yong Qiao, Bin Yu, Shu-Xia Cao, Hao Wang, Hui-Qian Huang, Hong Zhang, Xiao-Ming Li, Hong Lia. C3aR in the medial prefrontal cortex modulates the susceptibility to LPS-induced depressive-like behaviors through glutamatergic neuronal excitability. Progress in neurobiology. 2024-04-19. PMID:38641040. |
c3ar in the medial prefrontal cortex modulates the susceptibility to lps-induced depressive-like behaviors through glutamatergic neuronal excitability. |
2024-04-19 |
2024-04-22 |
mouse |
| Brenna C Duffy, Kirsten M King, Binod Nepal, Michael R Nonnemacher, Sandhya Kortager. Acute Administration of HIV-1 Tat Protein Drives Glutamatergic Alterations in a Rodent Model of HIV-Associated Neurocognitive Disorders. Molecular neurobiology. 2024-03-22. PMID:38514527. |
to identify changes in regional glutamatergic circuitry underlying cognitive impairment, we injected recombinant tat86 or saline to medial prefrontal cortex (mpfc) of male sprague-dawley rats. |
2024-03-22 |
2024-03-24 |
rat |
| Yehao Liu, Xiaoyu Zhou, Ke Xue, Ruiao Sun, Yan Tang, Chuanxi Tan. Reviving: restoring depression-like behaviour through glial cell-derived neurotrophic factor treatment in the medial prefrontal cortex. Journal of psychiatry & neuroscience : JPN. vol 49. issue 1. 2024-02-01. PMID:38302136. |
depression is a prevalent nonmotor symptom in parkinson disease and can greatly reduce the quality of life for patients; the dopamine receptors found in glutamatergic pyramidal cells in the medial prefrontal cortex (mpfc) play a role in regulating local field activity, which in turn affects behavioural and mood disorders. |
2024-02-01 |
2024-02-04 |
mouse |
| Ji Hyeong Baek, Hyeongchan Park, Hyeju Kang, Rankyung Kim, Jae Soon Kang, Hyun Joon Ki. The Role of Glutamine Homeostasis in Emotional and Cognitive Functions. International journal of molecular sciences. vol 25. issue 2. 2024-01-27. PMID:38279303. |
recent findings indicated that a neuronal gln deficiency in the medial prefrontal cortex in rodents led to depressive behaviors and mild cognitive impairment along with lower glutamatergic neurotransmission. |
2024-01-27 |
2024-01-29 |
Not clear |
| Jayapriya Chandrasekaran, Kevin K Caldwell, Jonathan L Brigma. Dynamic regulation of corticostriatal glutamatergic synaptic expression during reversal learning in male mice. Neurobiology of learning and memory. 2024-01-19. PMID:38242226. |
following training to well-established stages of discrimination and reversal learning on a touchscreen visual task, lateral orbitofrontal cortex (ofc), dorsal striatum (ds) as well as medial prefrontal cortex (mpfc), basolateral amygdala (bla) and piriform cortex (pir) were micro dissected from male mouse brain and the expression of glutamatergic receptor subunits in the synaptic fraction were measured via immunoblotting. |
2024-01-19 |
2024-01-22 |
mouse |
| Nicholas Spitzer, Marta Pratelli, Anna Hakimi, Arth Thaker, Hui-Quan Li, Swetha Godavarth. Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits. Research square. 2024-01-03. PMID:38168375. |
we find that both phencyclidine and methamphetamine, despite differing in their targets in the brain, cause the same glutamatergic neurons in the medial prefrontal cortex to gain a gabaergic phenotype and decrease their expression of the vesicular glutamate transporter. |
2024-01-03 |
2024-01-06 |
Not clear |
| Jiao-Zhao Yan, Guang-Xiang Li, Si-Rui Sun, Lin-Yu Cui, Yong-Yu Yin, Yun-Feng L. A critical step in antidepressants onset: Excitation of glutamatergic pyramidal neurons in rodents' medial prefrontal cortex. Progress in neuro-psychopharmacology & biological psychiatry. 2023-12-08. PMID:38065287. |
a critical step in antidepressants onset: excitation of glutamatergic pyramidal neurons in rodents' medial prefrontal cortex. |
2023-12-08 |
2023-12-17 |
mouse |
| Jiao-Zhao Yan, Guang-Xiang Li, Si-Rui Sun, Lin-Yu Cui, Yong-Yu Yin, Yun-Feng L. A critical step in antidepressants onset: Excitation of glutamatergic pyramidal neurons in rodents' medial prefrontal cortex. Progress in neuro-psychopharmacology & biological psychiatry. 2023-12-08. PMID:38065287. |
we investigated the behavioral effects of five different antidepressants (differing in target, chemical structure, and rate of onset) and their effects on the firing activities of glutamatergic pyramidal neurons in the medial prefrontal cortex (mpfc) using the forced swimming test (fst) and electrophysiological techniques (in vivo). |
2023-12-08 |
2023-12-17 |
mouse |