| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mark W Mille. GABA as a Neurotransmitter in Gastropod Molluscs. The Biological bulletin. vol 236. issue 2. 2019-06-17. PMID:30933636. |
the functional properties of gabaergic neurons in simpler gastropod systems may provide insight into the role of this neurotransmitter phenotype in more complex brains. |
2019-06-17 |
2023-08-13 |
Not clear |
| David M Lovinge. Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking. Handbook of experimental pharmacology. vol 248. 2019-06-12. PMID:29204712. |
prolonged exposure to ethanol alters neurotransmitter release at many cns gabaergic and glutamatergic synapses, and changes in gpcr function are implicated in many of these neuroadaptations. |
2019-06-12 |
2023-08-13 |
Not clear |
| Verginia C Cuzon Carlso. GABA and Glutamate Synaptic Coadaptations to Chronic Ethanol in the Striatum. Handbook of experimental pharmacology. vol 248. 2019-06-12. PMID:29460153. |
alcohol exerts its actions through multiple neurotransmitter systems within the brain, most notably the gabaergic and glutamatergic systems. |
2019-06-12 |
2023-08-13 |
Not clear |
| Ruth L O'Gorman Tuura, Christian R Baumann, Heide Baumann-Voge. Neurotransmitter activity is linked to outcome following subthalamic deep brain stimulation in Parkinson's disease. Parkinsonism & related disorders. vol 50. 2019-06-12. PMID:29472099. |
the activity within the primary inhibitory (gabaergic) and excitatory (glutamatergic) neurotransmitter systems may therefore play an important role in the therapeutic efficacy of dbs in pd. |
2019-06-12 |
2023-08-13 |
Not clear |
| Mahmoud Aarabi, Elena Kessler, Suneeta Madan-Khetarpal, Urvashi Surti, Daniel Bellissimo, Aleksandar Rajkovic, Svetlana A Yatsenk. Autism spectrum disorder in females with ARHGEF9 alterations and a random pattern of X chromosome inactivation. European journal of medical genetics. vol 62. issue 4. 2019-04-01. PMID:30048823. |
proper function of gabaergic synapses depends upon the postsynaptic compartment anchoring of neurotransmitter receptors to the membrane by gephyrin and collybistin (cb). |
2019-04-01 |
2023-08-13 |
Not clear |
| Roger F Butterwort. Hepatic Encephalopathy in Cirrhosis: Pathology and Pathophysiology. Drugs. vol 79. issue Suppl 1. 2019-03-26. PMID:30706423. |
pathophysiology of he in cirrhosis is multifactorial, involving brain accumulation of ammonia and manganese, systemic and central inflammation, nutritional/metabolic factors and activation of the gabaergic neurotransmitter system. |
2019-03-26 |
2023-08-13 |
Not clear |
| T Schmidt-Wilcke, E Fuchs, K Funke, A Vlachos, F Müller-Dahlhaus, N A J Puts, R E Harris, R A E Edde. GABA-from Inhibition to Cognition: Emerging Concepts. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 24. issue 5. 2019-02-25. PMID:29283020. |
gaba is the main inhibitory neurotransmitter in the adult mammalian brain and, depending on the brain region, up to 25% of the total number of cortical neurons are gabaergic interneurons. |
2019-02-25 |
2023-08-13 |
human |
| Jennifer J Donegan, Angela M Boley, Daniel J Lodg. Embryonic stem cell transplants as a therapeutic strategy in a rodent model of autism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 8. 2019-02-14. PMID:29453447. |
the neurobiology of autism is complex, but converging evidence suggests that asd involves disruptions in the inhibitory gabaergic neurotransmitter system. |
2019-02-14 |
2023-08-13 |
Not clear |
| Jun-Xi Pan, Jin-Jun Xia, Feng-Li Deng, Wei-Wei Liang, Jing Wu, Bang-Min Yin, Mei-Xue Dong, Jian-Jun Chen, Fei Ye, Hai-Yang Wang, Peng Zheng, Peng Xi. Diagnosis of major depressive disorder based on changes in multiple plasma neurotransmitters: a targeted metabolomics study. Translational psychiatry. vol 8. issue 1. 2019-02-04. PMID:29991685. |
here, using a gc-ms coupled with lc-ms/ms-based targeted metabolomics approach, we simultaneously quantified the levels of 19 plasma metabolites involved in gabaergic, catecholaminergic, and serotonergic neurotransmitter systems in 50 first-episode, antidepressant drug-naïve mdd subjects and 50 healthy controls to identify potential metabolite biomarkers for mdd (training set). |
2019-02-04 |
2023-08-13 |
human |
| Prashant Koshal, Sumit Jamwal, Puneet Kuma. Glucagon-like Peptide-1 (GLP-1) and neurotransmitters signaling in epilepsy: An insight review. Neuropharmacology. vol 136. issue Pt B. 2019-01-17. PMID:29129776. |
numerous studies have suggested that an imbalance in glutamatergic (excitatory) and gabaergic (inhibitory) neurotransmitter system is one of the dominating pathophysiological mechanisms underlying the occurrence and progression of seizures. |
2019-01-17 |
2023-08-13 |
human |
| Marco Antônio Peliky Fontes, Gisele Cristiane Vaz, Thais Zielke Dias Cardoso, Mariana Flávia de Oliveira, Maria José Campagnole-Santos, Robson Augusto Souza Dos Santos, Neeru M Sharma, Kaushik P Patel, Frédéric Frézar. GABA-containing liposomes: neuroscience applications and translational perspectives for targeting neurological diseases. Nanomedicine : nanotechnology, biology, and medicine. vol 14. issue 3. 2018-12-17. PMID:29278747. |
gaba is the main inhibitory neurotransmitter in the central nervous system, and dysfunction of gabaergic mechanisms is associated with different neurological conditions. |
2018-12-17 |
2023-08-13 |
Not clear |
| Maurice Garret, Zhuowei Du, Marine Chazalon, Yoon H Cho, Jérôme Baufreto. Alteration of GABAergic neurotransmission in Huntington's disease. CNS neuroscience & therapeutics. vol 24. issue 4. 2018-12-11. PMID:29464851. |
in addition to well-established alterations of glutamatergic and dopaminergic neurotransmitter systems, it is becoming clear that the gabaergic systems are also impaired in hd. |
2018-12-11 |
2023-08-13 |
Not clear |
| Maurice Garret, Zhuowei Du, Marine Chazalon, Yoon H Cho, Jérôme Baufreto. Alteration of GABAergic neurotransmission in Huntington's disease. CNS neuroscience & therapeutics. vol 24. issue 4. 2018-12-11. PMID:29464851. |
gaba is the major inhibitory neurotransmitter in the brain, and gabaergic neurotransmission has been postulated to be modified in many neurological and psychiatric diseases. |
2018-12-11 |
2023-08-13 |
Not clear |
| Clare R Gamlin, Wan-Qing Yu, Rachel O L Wong, Mrinalini Hoo. Assembly and maintenance of GABAergic and Glycinergic circuits in the mammalian nervous system. Neural development. vol 13. issue 1. 2018-11-15. PMID:29875009. |
inhibitory synapses are generally gabaergic or glycinergic, although there are synapses that co-release both neurotransmitter types. |
2018-11-15 |
2023-08-13 |
Not clear |
| Dhani Biscocho, Jayce G Cook, Joshua Long, Nishant Shah, Esther M Leis. GABA is an inhibitory neurotransmitter in the neural circuit regulating metamorphosis in a marine snail. Developmental neurobiology. vol 78. issue 7. 2018-11-08. PMID:29663674. |
our investigations into the responses of larval t. obsoleta to multiple gabaergic reagents support our hypothesis that gaba functions internally as a neurotransmitter in the pathway that controls the initiation of metamorphosis. |
2018-11-08 |
2023-08-13 |
Not clear |
| Upasana Roy, Lara Stute, Corinna Höfling, Maike Hartlage-Rübsamen, Jörg Matysik, Steffen Roβner, A Ali. Sex- and age-specific modulation of brain GABA levels in a mouse model of Alzheimer's disease. Neurobiology of aging. vol 62. 2018-09-26. PMID:29154037. |
among the neurotransmitter systems, gamma-aminobutyric acid (gaba) has been implicated in ad pathogenesis but the relevance of sex-specific gabaergic dysfunction during ad progression remains unknown. |
2018-09-26 |
2023-08-13 |
mouse |
| Freja Bertelsen, Anne M Landau, Karina H Vase, Jan Jacobsen, Jørgen Scheel-Krüger, Arne Mølle. Acute in vivo effect of valproic acid on the GABAergic system in rat brain: A [ Brain research. vol 1680. 2018-08-14. PMID:29258847. |
acute in vivo effect of valproic acid on the gabaergic system in rat brain: a [ γ-aminobutyric acid (gaba) is the primary inhibitory neurotransmitter in the nervous system acting mainly through gaba |
2018-08-14 |
2023-08-13 |
rat |
| Santosh K Mandal, Prem K Shrestha, Fahaad S H Alenazi, Manita Shakya, Hussain Alhamami, Karen P Brisk. Role of hindbrain adenosine 5'-monophosphate-activated protein kinase (AMPK) in hypothalamic AMPK and metabolic neuropeptide adaptation to recurring insulin-induced hypoglycemia in the male rat. Neuropeptides. vol 66. 2018-06-27. PMID:28823463. |
it remains unclear if 'glucose-excited' vmh gabaergic and/or arh pro-opiomelanocortin neurons exhibit ampk habituation to riih, and whether diminished sensor activation in these and other mediobasal hypothalamic neurotransmitter populations may contribute to haaf. |
2018-06-27 |
2023-08-13 |
rat |
| Yue Wang, Zheng Wu, Yu-Ting Bai, Gang-Yi Wu, Gong Che. Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer's disease. Molecular neurodegeneration. vol 12. issue 1. 2018-06-08. PMID:29017573. |
although dysfunction of multiple neurotransmitter systems including cholinergic, glutamatergic and gabaergic systems has been associated with ad progression the underlying mechanisms remain elusive. |
2018-06-08 |
2023-08-13 |
mouse |
| Jacobine Kuijlaars, Tutu Oyelami, Annick Diels, Jutta Rohrbacher, Sofie Versweyveld, Giulia Meneghello, Marianne Tuefferd, Peter Verstraelen, Jan R Detrez, Marlies Verschuuren, Winnok H De Vos, Theo Meert, Pieter J Peeters, Miroslav Cik, Rony Nuydens, Bert Brône, An Verheye. Sustained synchronized neuronal network activity in a human astrocyte co-culture system. Scientific reports. vol 6. 2018-05-07. PMID:27819315. |
the cells express gabaergic and glutamatergic markers and respond to inhibitors of both neurotransmitter pathways in a functional assay. |
2018-05-07 |
2023-08-13 |
human |