| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Henry R Kranzler, Howard J Edenber. Pharmacogenetics of alcohol and alcohol dependence treatment. Current pharmaceutical design. vol 16. issue 19. 2010-10-08. PMID:20482509. |
we consider four neurotransmitter systems: opioidergic, dopaminergic, gabaergic, and glutamatergic and focus on one receptor protein in each: oprm1 (the &#micro;-opioid receptor gene), drd4 (the d(4) dopamine receptor gene), gabra2 (gaba(a) receptor alpha-2 subunit gene), and grik1 (the kainite receptor glur5 subunit gene). |
2010-10-08 |
2023-08-12 |
Not clear |
| Christiaan H Vinkers, Ruud van Oorschot, S Mechiel Korte, Berend Olivier, Lucianne Groenin. 5-HT1A receptor blockade reverses GABA(A) receptor alpha3 subunit-mediated anxiolytic effects on stress-induced hyperthermia. Psychopharmacology. vol 211. issue 2. 2010-09-24. PMID:20535452. |
stress-related disorders are associated with dysfunction of both serotonergic and gabaergic pathways, and clinically effective anxiolytics act via both neurotransmitter systems. |
2010-09-24 |
2023-08-12 |
Not clear |
| Christophe Heinrich, Robert Blum, Sergio Gascón, Giacomo Masserdotti, Pratibha Tripathi, Rodrigo Sánchez, Steffen Tiedt, Timm Schroeder, Magdalena Götz, Benedikt Berninge. Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS biology. vol 8. issue 5. 2010-08-24. PMID:20502524. |
importantly, the neurotransmitter fate choice of astroglia-derived neurons can be controlled by selective expression of distinct neurogenic transcription factors: forced expression of the dorsal telencephalic fate determinant neurogenin-2 (neurog2) directs cortical astroglia to generate synapse-forming glutamatergic neurons; in contrast, the ventral telencephalic fate determinant dlx2 induces a gabaergic identity, although the overall efficiency of dlx2-mediated neuronal reprogramming is much lower compared to neurog2, suggesting that cortical astroglia possess a higher competence to respond to the dorsal telencephalic fate determinant. |
2010-08-24 |
2023-08-12 |
Not clear |
| Shan He, Jun Ma, Na Liu, Xiang Y. Early enriched environment promotes neonatal GABAergic neurotransmission and accelerates synapse maturation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 23. 2010-08-24. PMID:20534839. |
this enhanced gabaergic synaptic transmission persisted until the end of the second postnatal week, when gaba mostly acts as an inhibitory neurotransmitter. |
2010-08-24 |
2023-08-12 |
mouse |
| Charisse Flerida A Pasaje, Jeong-Hyun Kim, Byung-Lae Park, Hyun Sub Cheong, Ji-Yong Chun, Tae-Joon Park, Jin-Sol Lee, Yongha Kim, Joon Seol Bae, Jong Sook Park, Sang-Hyuk Yoon, Soo-Taek Uh, Jae-Sung Choi, Yong-Hoon Kim, Mi-Kyeong Kim, Inseon S Choi, Sang Heon Cho, Byoung Whui Choi, Choon-Sik Park, Hyoung Doo Shi. Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population. Annals of human genetics. vol 74. issue 4. 2010-08-05. PMID:20597903. |
the critical role of the solute carrier family 6 (neurotransmitter transporter, betaine/gaba) member 12 (slc6a12) gene in gabaergic transmission, which is associated with mucus production in asthma, makes it a candidate gene for aia association study. |
2010-08-05 |
2023-08-12 |
Not clear |
| ChiHye Chung, Barbara Barylko, Jeremy Leitz, Xinran Liu, Ege T Kavalal. Acute dynamin inhibition dissects synaptic vesicle recycling pathways that drive spontaneous and evoked neurotransmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 4. 2010-07-08. PMID:20107062. |
here, we used a reversible inhibitor of dynamin, dynasore, to dissect the vesicle pool dynamics underlying the three forms of neurotransmitter release in hippocampal gabaergic inhibitory synapses. |
2010-07-08 |
2023-08-12 |
Not clear |
| Magdalena Wolańczyk, Krystyna Hułas-Bigoszewska, Monika Witusik-Perkowska, Wielisław Papierz, Dariusz Jaskólski, Paweł P Liberski, Piotr Riesk. Imperfect oligodendrocytic and neuronal differentiation of glioblastoma cells. Folia neuropathologica. vol 48. issue 1. 2010-07-02. PMID:20383808. |
currently, we decided to check if changes in expression of: th (tyrosine hydroxylase, marker of catecholaminergic cells) and gaba (neurotransmitter of gabaergic neurons) and markers of oligodendrocytic cells (o4, cnp) occur during the exposure of gbm cells to the differentiation medium. |
2010-07-02 |
2023-08-12 |
Not clear |
| Shireen Sultana, Huifen Li, Adam Puche, Odell Jones, Joseph L Bryant, Walter Roya. Quantitation of parvalbumin+ neurons and human immunodeficiency virus type 1 (HIV-1) regulatory gene expression in the HIV-1 transgenic rat: effects of vitamin A deficiency and morphine. Journal of neurovirology. vol 16. issue 1. 2010-06-01. PMID:20113193. |
in contrast, numbers of neurons that expressed the calcium-binding protein parvalbumin, which is a marker interneurons that express the inhibitory neurotransmitter gamma-aminobutyric acid (gabaergic neurons) were decreased for wild-type (wt) rats on the va-deficient diet and for wt rats treated with morphine. |
2010-06-01 |
2023-08-12 |
human |
| L Bragina, S Giovedì, P Barbaresi, F Benfenati, F Cont. Heterogeneity of glutamatergic and GABAergic release machinery in cerebral cortex: analysis of synaptogyrin, vesicle-associated membrane protein, and syntaxin. Neuroscience. vol 165. issue 3. 2010-03-08. PMID:19909789. |
moreover, we studied the localization of stx1b at the electron microscope and found that a population of axon terminals forming symmetric synapses were stx1b-positive.these results extend our previous observations on the differential expression of presynaptic proteins involved in neurotransmitter release in gabaergic and glutamatergic terminals and indicate that heterogeneity of glutamatergic and gabaergic release machinery can be contributed by both the presence or absence of a given protein in a nerve terminal and the amount of protein expressed by synaptic vesicles. |
2010-03-08 |
2023-08-12 |
rat |
| Vinicia Campana Biancardi, Ruy Ribeiro Campos, Javier Eduardo Ster. Altered balance of gamma-aminobutyric acidergic and glutamatergic afferent inputs in rostral ventrolateral medulla-projecting neurons in the paraventricular nucleus of the hypothalamus of renovascular hypertensive rats. The Journal of comparative neurology. vol 518. issue 5. 2010-03-08. PMID:20034060. |
our results indicate that, along with previously described changes in neurotransmitter release probability and postsynaptic receptor function, remodeling of gabaergic and glutamatergic afferent inputs contributes as an underlying mechanism to the altered excitatory/inhibitory balance in the pvn of hypertensive rats. |
2010-03-08 |
2023-08-12 |
rat |
| P Emanuela Voinescu, P Emanuela, Jeremy N Kay, Joshua R Sane. Birthdays of retinal amacrine cell subtypes are systematically related to their molecular identity and soma position. The Journal of comparative neurology. vol 517. issue 5. 2010-02-24. PMID:19827163. |
we used antibody markers to identify the two main amacrine subsets--gabaergic and glycinergic--and further subdivided these groups into smaller subsets based on expression of neurotransmitter and transcription factor markers. |
2010-02-24 |
2023-08-12 |
mouse |
| Alex Iranzo, Joan Santamaria, Eduard Tolos. The clinical and pathophysiological relevance of REM sleep behavior disorder in neurodegenerative diseases. Sleep medicine reviews. vol 13. issue 6. 2010-02-23. PMID:19362028. |
), leading to a complex multiple neurotransmitter dysfunction that involves gabaergic, glutamatergic and monoaminergic systems. |
2010-02-23 |
2023-08-12 |
human |
| Pieter van Eijsden, Kevin L Behar, Graeme F Mason, Kees P J Braun, Robin A de Graa. In vivo neurochemical profiling of rat brain by 1H-[13C] NMR spectroscopy: cerebral energetics and glutamatergic/GABAergic neurotransmission. Journal of neurochemistry. vol 112. issue 1. 2010-02-08. PMID:19818103. |
using (1)h-[(13)c] nmr spectroscopy at high magnetic field in combination with robust spectral modeling and the use of different substrates, [u-(13)c(6)]-glucose and [2-(13)c]-acetate, it is shown that gabaergic, as well as glutamatergic neurotransmitter fluxes can be detected non-invasively in rat brain in vivo. |
2010-02-08 |
2023-08-12 |
rat |
| Richard A E Edden, Suresh D Muthukumaraswamy, Tom C A Freeman, Krish D Sing. Orientation discrimination performance is predicted by GABA concentration and gamma oscillation frequency in human primary visual cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016087. |
these results confirm the importance of gabaergic inhibition in orientation selectivity and demonstrate, for the first time, that interindividual performance on a simple visual task is linked to neurotransmitter concentration. |
2010-01-26 |
2023-08-12 |
human |
| Steffen Scholpp, Alessio Delogu, Jonathan Gilthorpe, Daniela Peukert, Simone Schindler, Andrew Lumsde. Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 47. 2010-01-14. PMID:19903880. |
here we find that her6 determines not only the onset of neurogenesis but also the identity of thalamic neurons, marked by proneural and neurotransmitter gene expression: loss of her6 leads to premature neurogenin1-mediated genesis of glutamatergic (excitatory) neurons, whereas maintenance of her6 leads to ascl1-mediated production of gabaergic (inhibitory) neurons. |
2010-01-14 |
2023-08-12 |
zebrafish |
| Neal C Burton, Jay S Schneider, Tore Syversen, Tomás R Guilart. Effects of chronic manganese exposure on glutamatergic and GABAergic neurotransmitter markers in the nonhuman primate brain. Toxicological sciences : an official journal of the Society of Toxicology. vol 111. issue 1. 2009-12-03. PMID:19520674. |
effects of chronic manganese exposure on glutamatergic and gabaergic neurotransmitter markers in the nonhuman primate brain. |
2009-12-03 |
2023-08-12 |
monkey |
| Neal C Burton, Jay S Schneider, Tore Syversen, Tomás R Guilart. Effects of chronic manganese exposure on glutamatergic and GABAergic neurotransmitter markers in the nonhuman primate brain. Toxicological sciences : an official journal of the Society of Toxicology. vol 111. issue 1. 2009-12-03. PMID:19520674. |
available evidence in rodents suggests that mn causes dysregulation of glutamatergic and gamma-aminobutyric acidergic (gabaergic) neurotransmitter systems. |
2009-12-03 |
2023-08-12 |
monkey |
| John F Bowyer, John R Latendresse, Robert R Delongchamp, Alan R Warbritton, Monzy Thomas, Becky Divine, Daniel R Doerg. The mRNA expression and histological integrity in rat forebrain motor and sensory regions are minimally affected by acrylamide exposure through drinking water. Toxicology and applied pharmacology. vol 240. issue 3. 2009-10-26. PMID:19664650. |
very few, if any, statistically significant changes were seen in mrna levels of the more than 50 genes directly related to the cholinergic, noradrenergic, gabaergic or glutamatergic neurotransmitter systems in the striatum, substantia nigra or parietal cortex. |
2009-10-26 |
2023-08-12 |
rat |
| Ivan Pavlov, Matthew C Walker, Dimitri M Kullman. Computational sophistication at a single GABAergic connection. Neuron. vol 63. issue 6. 2009-10-09. PMID:19778499. |
diverse computational roles of gabaergic inhibition are often assumed to reflect heterogeneity in the sources of gaba and in the receptors sensing the neurotransmitter. |
2009-10-09 |
2023-08-12 |
Not clear |
| Haisong Jiang, Mengqing Xian. Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 33. 2009-09-11. PMID:19692620. |
these data suggest that nr4a2 is both necessary and sufficient to confer ac precursors with the identity of a gabaergic ac phenotype, and that it may network with multiple other retinogenic factors to ensure proper specification and differentiation of ac neurotransmitter subtypes. |
2009-09-11 |
2023-08-12 |
mouse |