| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Liang, Igor Spigelman, Richard W Olse. Tolerance to sedative/hypnotic actions of GABAergic drugs correlates with tolerance to potentiation of extrasynaptic tonic currents of alcohol-dependent rats. Journal of neurophysiology. vol 102. issue 1. 2009-09-10. PMID:19420124. |
we previously observed variably altered sensitivity to gabaergic drugs in vivo and in hippocampal neurons using whole cell patch-clamp recording in brain slices. |
2009-09-10 |
2023-08-12 |
rat |
| Giovanni Biggio, Maria Cristina Mostallino, Paolo Follesa, Alessandra Concas, Enrico Sann. GABA(A) receptor function and gene expression during pregnancy and postpartum. International review of neurobiology. vol 85. 2009-09-10. PMID:19607962. |
in different brain regions, such as the hippocampus, different subpopulations of nerve cells exhibit two components of inhibitory gabaergic transmission: a phasic component mediated by synaptic gaba(a)-rs, and a tonic component mediated by "ambient" gaba acting at extrasynaptic gaba(a)-rs mainly containing the delta subunit and endowed with a higher sensitivity to neuroactive steroids compared to synaptic receptors. |
2009-09-10 |
2023-08-12 |
rat |
| Allison M Bond, Michael J W Vangompel, Evgeny A Sametsky, Mary F Clark, Julie C Savage, John F Disterhoft, Jhumku D Koht. Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry. Nature neuroscience. vol 12. issue 8. 2009-09-09. PMID:19620975. |
evf2 mouse mutants had reduced numbers of gabaergic interneurons in early postnatal hippocampus and dentate gyrus. |
2009-09-09 |
2023-08-12 |
mouse |
| Allison M Bond, Michael J W Vangompel, Evgeny A Sametsky, Mary F Clark, Julie C Savage, John F Disterhoft, Jhumku D Koht. Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry. Nature neuroscience. vol 12. issue 8. 2009-09-09. PMID:19620975. |
although the numbers of gabaergic interneurons and gad1 rna levels returned to normal in evf2 mutant adult hippocampus, reduced synaptic inhibition occurred. |
2009-09-09 |
2023-08-12 |
mouse |
| Yury M Morozov, Masaaki Torii, Pasko Raki. Origin, early commitment, migratory routes, and destination of cannabinoid type 1 receptor-containing interneurons. Cerebral cortex (New York, N.Y. : 1991). vol 19 Suppl 1. 2009-09-02. PMID:19346272. |
we have followed their migration, first radially to the marginal zone, then tangentially in the lateral-to-medial direction within the dorsal telencephalon, before they reach their final destination in the hippocampus proper and the dentate gyrus where they differentiate into cb(1)/cck+ or cb(1)/reelin/calretinin+ gabaergic interneurons. |
2009-09-02 |
2023-08-12 |
Not clear |
| J J Roland, L M Savag. The role of cholinergic and GABAergic medial septal/diagonal band cell populations in the emergence of diencephalic amnesia. Neuroscience. vol 160. issue 1. 2009-08-17. PMID:19264109. |
the septohippocampal pathway, which is mostly composed of cholinergic and gabaergic projections between the medial septum/diagonal band (ms/db) and the hippocampus, has an established role in learning, memory and disorders of cognition. |
2009-08-17 |
2023-08-12 |
rat |
| Yong-Hong Liu, Lian Wang, Li-Chun Wei, Yuan-Gui Huang, Liang-Wei Che. Up-regulation of D-serine might induce GABAergic neuronal degeneration in the cerebral cortex and hippocampus in the mouse pilocarpine model of epilepsy. Neurochemical research. vol 34. issue 7. 2009-08-10. PMID:19123037. |
up-regulation of d-serine might induce gabaergic neuronal degeneration in the cerebral cortex and hippocampus in the mouse pilocarpine model of epilepsy. |
2009-08-10 |
2023-08-12 |
mouse |
| Diego M Gelman, Francisco J Martini, Sandrina Nóbrega-Pereira, Alessandra Pierani, Nicoletta Kessaris, Oscar Marí. The embryonic preoptic area is a novel source of cortical GABAergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 29. 2009-08-10. PMID:19625528. |
in utero labeling and genetic lineage-tracing experiments demonstrate that neurons born in this region migrate to the neocortex and hippocampus, where they differentiate into a distinct population of gabaergic interneurons with relatively uniform neurochemical, morphological, and electrophysiological properties. |
2009-08-10 |
2023-08-12 |
mouse |
| Marco Mula, Francesco Monac. Antiepileptic drugs and psychopathology of epilepsy: an update. Epileptic disorders : international epilepsy journal with videotape. vol 11. issue 1. 2009-08-05. PMID:19258231. |
depression seems to be linked with aeds potentiating gabaergic neurotransmission in patients with limbic system abnormalities such as hippocampal sclerosis. |
2009-08-05 |
2023-08-12 |
Not clear |
| Balázs Hangya, Zsolt Borhegyi, Nóra Szilágyi, Tamás F Freund, Viktor Varg. GABAergic neurons of the medial septum lead the hippocampal network during theta activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 25. 2009-08-04. PMID:19553449. |
gabaergic neurons of the medial septum lead the hippocampal network during theta activity. |
2009-08-04 |
2023-08-12 |
Not clear |
| Mariko Sekiguchi, Fumihiko Hayashi, Kunihiro Tsuchida, Kaoru Inokuch. Neuron type-selective effects of activin on development of the hippocampus. Neuroscience letters. vol 452. issue 3. 2009-07-27. PMID:19348730. |
continuous treatment of hippocampal cultures with activin suppressed the emergence of gad67(+) neurons, which are a subtype of gabaergic interneurons, and increased the percentage of prox1(+) neurons, which are dentate granule cells. |
2009-07-27 |
2023-08-12 |
Not clear |
| Hiroko Bannai, Sabine Lévi, Claude Schweizer, Takafumi Inoue, Thomas Launey, Victor Racine, Jean-Baptiste Sibarita, Katsuhiko Mikoshiba, Antoine Trille. Activity-dependent tuning of inhibitory neurotransmission based on GABAAR diffusion dynamics. Neuron. vol 62. issue 5. 2009-06-26. PMID:19524526. |
we report here that neuronal activity modifies diffusion properties of type-a gaba receptors (gaba(a)r) in cultured hippocampal neurons: enhanced excitatory synaptic activity decreases the cluster size of gaba(a)rs and reduces gabaergic mipsc. |
2009-06-26 |
2023-08-12 |
Not clear |
| Sampsa T Sipilä, Kristiina Huttu, Junko Yamada, Ramil Afzalov, Juha Voipio, Peter Blaesse, Kai Kail. Compensatory enhancement of intrinsic spiking upon NKCC1 disruption in neonatal hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 21. 2009-06-23. PMID:19474325. |
hence, developmental expression of kcc2, unsilencing of ampa-type synapses, and early network events can take place in the absence of excitatory gabaergic signaling in the neonatal hippocampus. |
2009-06-23 |
2023-08-12 |
mouse |
| Flavia Doná, Henning Ulrich, Daniele Suzete Persike, Isaltino Marcelo Conceição, João Paulo Blini, Esper Abrão Cavalheiro, Maria José Silva Fernande. Alteration of purinergic P2X4 and P2X7 receptor expression in rats with temporal-lobe epilepsy induced by pilocarpine. Epilepsy research. vol 83. issue 2-3. 2009-06-22. PMID:19084381. |
however, the reduction of hippocampal p2x(4) receptor immunostaining in the chronic phase could reflect neuronal loss or decreased gabaergic signaling. |
2009-06-22 |
2023-08-12 |
rat |
| P P Tripathi, P Sgadò, M Scali, C Viaggi, S Casarosa, H H Simon, F Vaglini, G U Corsini, Y Bozz. Increased susceptibility to kainic acid-induced seizures in Engrailed-2 knockout mice. Neuroscience. vol 159. issue 2. 2009-06-17. PMID:19186208. |
indeed, a reduced expression of parvalbumin and somatostatin was detected in the hippocampus of en2(-/-) mice as compared to wild-type (wt) mice, indicating an altered gabaergic innervation of limbic circuits in en2(-/-) mice. |
2009-06-17 |
2023-08-12 |
mouse |
| Derya Sargin, Imam Hassouna, Swetlana Sperling, Anna-Leena Sirén, Hannelore Ehrenreic. Uncoupling of neurodegeneration and gliosis in a murine model of juvenile cortical lesion. Glia. vol 57. issue 7. 2009-06-08. PMID:18985736. |
whereas the total number of neurons and astrocytes in these brain regions remain unaltered, pointing to a non- gliotic neurodegeneration (as seen in schizophrenia), the subgroup of parvalbumin-positive inhibitory gabaergic interneurons is increased bilaterally in the hippocampus, as is the expression of the gaba-synthesizing enzyme gad67. |
2009-06-08 |
2023-08-12 |
mouse |
| Katrin Hoffmann, Elena Sivukhina, Heidrun Potschka, Melitta Schachner, Wolfgang Löscher, Alexander Dityate. Retarded kindling progression in mice deficient in the extracellular matrix glycoprotein tenascin-R. Epilepsia. vol 50. issue 4. 2009-05-12. PMID:19178559. |
the idea that tnr may be important for this process was suggested by previous studies showing that deficiency in tnr leads to abnormalities in synaptic plasticity, perisomatic gabaergic inhibition and more astrocytes in the hippocampus of adult mice. |
2009-05-12 |
2023-08-12 |
mouse |
| János Szabadics, Ivan Soltes. Functional specificity of mossy fiber innervation of GABAergic cells in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 13. 2009-04-23. PMID:19339618. |
functional specificity of mossy fiber innervation of gabaergic cells in the hippocampus. |
2009-04-23 |
2023-08-12 |
rat |
| R Ogier, L J Wrobel, M Raggenbas. Action of tachykinins in the hippocampus: facilitation of inhibitory drive to GABAergic interneurons. Neuroscience. vol 156. issue 3. 2009-04-14. PMID:18775478. |
action of tachykinins in the hippocampus: facilitation of inhibitory drive to gabaergic interneurons. |
2009-04-14 |
2023-08-12 |
rat |
| R Ogier, L J Wrobel, M Raggenbas. Action of tachykinins in the hippocampus: facilitation of inhibitory drive to GABAergic interneurons. Neuroscience. vol 156. issue 3. 2009-04-14. PMID:18775478. |
by acting on neurokinin 1 (nk1) receptors, neuropeptides of the tachykinin family can powerfully excite rat hippocampal gabaergic interneurons located in the ca1 region and by this way indirectly inhibit ca1 pyramidal neurons. |
2009-04-14 |
2023-08-12 |
rat |