| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tianpeng Zhang, Fangjun Yu, Haiman Xu, Min Chen, Xun Chen, Lianxia Guo, Cui Zhou, Yuting Xu, Fei Wang, Jiandong Yu, Baojian W. Dysregulation of REV-ERBα impairs GABAergic function and promotes epileptic seizures in preclinical models. Nature communications. vol 12. issue 1. 2021-03-02. PMID:33619249. |
rev-erbα ablation or antagonism also leads to prolonged spontaneous inhibitory postsynaptic currents and elevated frequency in the mouse hippocampus, indicating enhanced gabaergic signaling. |
2021-03-02 |
2023-08-13 |
mouse |
| John T Madden, Shannon M Thompson, Christy M Magcalas, Jennifer L Wagner, Derek A Hamilton, Daniel D Savage, Benjamin J Clark, Nathan S Pentkowsk. Moderate prenatal alcohol exposure reduces parvalbumin expressing GABAergic interneurons in the dorsal hippocampus of adult male and female rat offspring. Neuroscience letters. vol 718. 2021-03-01. PMID:31874217. |
moderate prenatal alcohol exposure reduces parvalbumin expressing gabaergic interneurons in the dorsal hippocampus of adult male and female rat offspring. |
2021-03-01 |
2023-08-13 |
rat |
| John T Madden, Shannon M Thompson, Christy M Magcalas, Jennifer L Wagner, Derek A Hamilton, Daniel D Savage, Benjamin J Clark, Nathan S Pentkowsk. Moderate prenatal alcohol exposure reduces parvalbumin expressing GABAergic interneurons in the dorsal hippocampus of adult male and female rat offspring. Neuroscience letters. vol 718. 2021-03-01. PMID:31874217. |
to explore the effects of moderate pae on gabaergic interneuron expression, this study used a rat model of moderate pae to examine the effects of pae on parvalbumin (parv)-positive cells in fields ca1, ca3 and the dentate gyrus (dg) of the dorsal hippocampus (dhc). |
2021-03-01 |
2023-08-13 |
rat |
| John T Madden, Shannon M Thompson, Christy M Magcalas, Jennifer L Wagner, Derek A Hamilton, Daniel D Savage, Benjamin J Clark, Nathan S Pentkowsk. Moderate prenatal alcohol exposure reduces parvalbumin expressing GABAergic interneurons in the dorsal hippocampus of adult male and female rat offspring. Neuroscience letters. vol 718. 2021-03-01. PMID:31874217. |
the results are discussed in relation to hippocampal gabaergic interneuron function, pae and behavior. |
2021-03-01 |
2023-08-13 |
rat |
| Lei Wu, Tian Zhang, Ken Chen, Chao Lu, Xiang Fei Liu, Jia Ling Zhou, Yun Ke Huang, Han Yan, Ying Chen, Chun Jie Zhang, Jun Feng Li, Shao Qi Shi, Ping Ren, Xi Huan. Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission. Phytotherapy research : PTR. vol 35. issue 1. 2021-02-23. PMID:33044778. |
consistent with ketamine, fra up-regulated the expressions of gabaergic receptor (gad67) and glutamatergic receptor 1 (glur1) in mouse hippocampus both exposed to lps and lh. |
2021-02-23 |
2023-08-13 |
mouse |
| Min-Ho Nam, Woojin Won, Kyung-Seok Han, C Justin Le. Signaling mechanisms of μ-opioid receptor (MOR) in the hippocampus: disinhibition versus astrocytic glutamate regulation. Cellular and molecular life sciences : CMLS. vol 78. issue 2. 2021-02-22. PMID:32671427. |
mor is distributed in various brain regions, including the hippocampus, where traditionally, it is believed to be localized mainly at the presynaptic terminals of the gabaergic inhibitory interneurons to exert a strong disinhibitory effect on excitatory pyramidal neurons. |
2021-02-22 |
2023-08-13 |
Not clear |
| Min-Ho Nam, Woojin Won, Kyung-Seok Han, C Justin Le. Signaling mechanisms of μ-opioid receptor (MOR) in the hippocampus: disinhibition versus astrocytic glutamate regulation. Cellular and molecular life sciences : CMLS. vol 78. issue 2. 2021-02-22. PMID:32671427. |
in this review, we focus on the two profoundly different hippocampal opioid signaling pathways through either gabaergic interneuronal or astrocytic mor. |
2021-02-22 |
2023-08-13 |
Not clear |
| Taavi Vanaveski, Svetlana Molchanova, Dan Duc Pham, Annika Schäfer, Ceren Pajanoja, Jane Narvik, Vignesh Srinivasan, Mari Urb, Maria Koivisto, Eero Vasar, Tönis Timmusk, Rimante Minkeviciene, Ove Eriksson, Maciej Lalowski, Tomi Taira, Laura Korhonen, Vootele Voikar, Dan Lindhol. PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice. Frontiers in molecular neuroscience. vol 14. 2021-02-19. PMID:33597848. |
these results demonstrate that pgc-1α regulates gabarα2 subunits and gabaergic neurotransmission in the hippocampus with behavioral consequences. |
2021-02-19 |
2023-08-13 |
mouse |
| Hyeonho Kim, Hyeji Jung, Hyunsu Jung, Seok-Kyu Kwon, Jaewon Ko, Ji Won U. The small GTPase ARF6 regulates GABAergic synapse development. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:31907062. |
here, we show that a subset of arf6 protein is localized at gabaergic synapses in cultured hippocampal neurons. |
2021-02-12 |
2023-08-13 |
mouse |
| Hyeonho Kim, Hyeji Jung, Hyunsu Jung, Seok-Kyu Kwon, Jaewon Ko, Ji Won U. The small GTPase ARF6 regulates GABAergic synapse development. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:31907062. |
arf6 kd also reduced gabaergic synaptic density in the mouse hippocampal dentate gyrus (dg) region. |
2021-02-12 |
2023-08-13 |
mouse |
| André Kougioumoutzakis, Joe Guillaume Pelletier, Isabel Laplante, Abdessattar Khlaifia, Jean-Claude Lacaill. TRPC1 mediates slow excitatory synaptic transmission in hippocampal oriens/alveus interneurons. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:31996247. |
hippocampal gabaergic interneurons play key roles in regulating principal cell activity and plasticity. |
2021-02-12 |
2023-08-13 |
Not clear |
| Vikram Babu Kasaragod, Anabel Pacios-Michelena, Natascha Schaefer, Fang Zheng, Nicole Bader, Christian Alzheimer, Carmen Villmann, Hermann Schindeli. Pyridoxal kinase inhibition by artemisinins down-regulates inhibitory neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 52. 2021-02-10. PMID:33318193. |
electrophysiological recordings from hippocampal slices and activity measurements of glutamic acid decarboxylase (gad), a plp-dependent enzyme synthesizing the neurotransmitter γ-aminobutyric acid (gaba), define how artemisinins also interfere presynaptically with gabaergic signaling. |
2021-02-10 |
2023-08-13 |
Not clear |
| Yuyang Wang, Junfa Wu, Hongyu Xie, Liping Wang, Chuanjie Wang, Yi W. Enriched Environment Promotes Cognitive Function Recovery following Cerebral Ischemic Injury via Upregulating GABAergic and Glutamatergic Systems in the Contralateral Hippocampus. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2021-01-30. PMID:33505485. |
enriched environment promotes cognitive function recovery following cerebral ischemic injury via upregulating gabaergic and glutamatergic systems in the contralateral hippocampus. |
2021-01-30 |
2023-08-13 |
mouse |
| Tristan Geiller, Bert Vancura, Satoshi Terada, Eirini Troullinou, Spyridon Chavlis, Grigorios Tsagkatakis, Panagiotis Tsakalides, Katalin Ócsai, Panayiota Poirazi, Balázs J Rózsa, Attila Losoncz. Large-Scale 3D Two-Photon Imaging of Molecularly Identified CA1 Interneuron Dynamics in Behaving Mice. Neuron. vol 108. issue 5. 2021-01-27. PMID:33022227. |
in the hippocampus, a large body of work has identified an unprecedented diversity of gabaergic interneurons with pronounced anatomical, molecular, and physiological differences. |
2021-01-27 |
2023-08-13 |
mouse |
| Julio D Perez, Susanne Tom Dieck, Beatriz Alvarez-Castelao, Georgi Tushev, Ivy Cw Chan, Erin M Schuma. Subcellular sequencing of single neurons reveals the dendritic transcriptome of GABAergic interneurons. eLife. vol 10. 2021-01-26. PMID:33404500. |
we separately profiled the dendritic and somatic transcriptomes of individual rat hippocampal neurons and investigated mrna abundances in the soma and dendrites of single glutamatergic and gabaergic neurons. |
2021-01-26 |
2023-08-13 |
rat |
| Viviam Sanabria, Simone Bittencourt, Sandra R Perosa, Tomás de la Rosa, Maria da Graça Naffah-Mazzacoratti, Monica L Andersen, Sergio Tufik, Esper A Cavalheiro, Débora Amad. Hormonal and biochemical changes in female Proechimys guyannensis, an animal model of resistance to pilocarpine-induced status epilepticus. Scientific reports. vol 10. issue 1. 2021-01-14. PMID:33268798. |
in ovx animals, a decrease in gabaergic receptors within 90 min of se may suggest that ovariectomy produces changes in the hippocampus, including a certain vulnerability to seizures. |
2021-01-14 |
2023-08-13 |
Not clear |
| Sylvia Badurek, Marilena Griguoli, Aman Asif-Malik, Barbara Zonta, Fei Guo, Silvia Middei, Laura Lagostena, Maria Teresa Jurado-Parras, Thomas H Gillingwater, Agnès Gruart, José María Delgado-García, Enrico Cherubini, Liliana Minichiell. Immature Dentate Granule Cells Require Ntrk2/Trkb for the Formation of Functional Hippocampal Circuitry. iScience. vol 23. issue 5. 2021-01-10. PMID:32361506. |
here, we show that early deletion of ntrk2/trkb from immature mouse hippocampal dentate granule cells (dgcs) affects the integration and maturation of newly formed dgcs in the hippocampal circuitry and drives a premature shift from depolarizing to hyperpolarizing gabaergic actions in the target of dgcs, the ca3 principal cells of the hippocampus, by reducing the expression of the cation-chloride importer nkcc1. |
2021-01-10 |
2023-08-13 |
mouse |
| Ayelén I Groisman, Sung M Yang, Alejandro F Schinde. Differential Coupling of Adult-Born Granule Cells to Parvalbumin and Somatostatin Interneurons. Cell reports. vol 30. issue 1. 2021-01-06. PMID:31914387. |
a strong gabaergic tone imposes sparse levels of activity in the dentate gyrus of the hippocampus. |
2021-01-06 |
2023-08-13 |
Not clear |
| Rachel Anne Hill, Adrienne Mary Grech, Michael J Notaras, Mauricio Sepulveda, Maarten van den Buus. Brain-Derived Neurotrophic Factor Val66Met polymorphism interacts with adolescent stress to alter hippocampal interneuron density and dendritic morphology in mice. Neurobiology of stress. vol 13. 2020-12-22. PMID:33344708. |
the current study used a humanized mouse model of the bdnf val66met polymorphism to determine how reduced activity-dependent release of bdnf, both on its own, and in combination with chronic adolescent stress hormone, impact hippocampal gabaergic interneuron cell density and dendrite morphology. |
2020-12-22 |
2023-08-13 |
mouse |
| Davide Lattanzi, Michael Di Palma, Riccardo Cuppini, Patrizia Ambrogin. GABAergic Input Affects Intracellular Calcium Levels in Developing Granule Cells of Adult Rat Hippocampus. International journal of molecular sciences. vol 21. issue 5. 2020-12-08. PMID:32138257. |
gabaergic input affects intracellular calcium levels in developing granule cells of adult rat hippocampus. |
2020-12-08 |
2023-08-13 |
rat |