| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D T Winkler, A L Scotti, C Nitsc. Ischemia-induced degeneration of CA1 pyramidal cells decreases seizure severity in a subgroup of epileptic gerbils and affects parvalbumin immunoreactivity of CA1 interneurons. Experimental neurology. vol 168. issue 2. 2001-05-10. PMID:11259124. |
in the hippocampus, seizure history of the individual animal is mirrored in the intensity in which gabaergic neurons are immunostained for the calcium-binding protein parvalbumin: they lose parvalbumin with increasing seizure incidence. |
2001-05-10 |
2023-08-12 |
Not clear |
| S Berretta, D W Munno, F M Bene. Amygdalar activation alters the hippocampal GABA system: "partial" modelling for postmortem changes in schizophrenia. The Journal of comparative neurology. vol 431. issue 2. 2001-04-26. PMID:11169995. |
to explore the possibility that changes in the hippocampal gabaergic system could be related to an increased inflow of activity originating in the amygdala, a "partial" animal model has been developed. |
2001-04-26 |
2023-08-12 |
rat |
| M C Walker, A Ruiz, D M Kullman. Monosynaptic GABAergic signaling from dentate to CA3 with a pharmacological and physiological profile typical of mossy fiber synapses. Neuron. vol 29. issue 3. 2001-04-26. PMID:11301029. |
gabaergic transmission from the dentate gyrus to ca3 has major implications not only for information flow into the hippocampus but also for developmental and pathological processes involving the hippocampus. |
2001-04-26 |
2023-08-12 |
Not clear |
| R F Squires, E Saederu. Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research. Neurochemical research. vol 25. issue 12. 2001-04-19. PMID:11152388. |
chronic administration of clozapine to rats was reported to significantly reduce the numbers of [3h]mus binding sites in temporal cortex and hippocampus which may be due to selective blockade of gaba(a) receptors on gabaergic interneurons that make synaptic contact with pyramidal cells. |
2001-04-19 |
2023-08-12 |
rat |
| B Hassel, E Taubøll, L Gjersta. Chronic lamotrigine treatment increases rat hippocampal GABA shunt activity and elevates cerebral taurine levels. Epilepsy research. vol 43. issue 2. 2001-04-19. PMID:11164704. |
the results suggest that chronic lamotrigine treatment increases gabaergic activity in the hippocampus. |
2001-04-19 |
2023-08-12 |
rat |
| D Bai, G Zhu, P Pennefather, M F Jackson, J F MacDonald, B A Orse. Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons. Molecular pharmacology. vol 59. issue 4. 2001-04-19. PMID:11259626. |
patch-clamp techniques were used to characterize miniature inhibitory postsynaptic currents (mipscs) and the tonic gabaergic current recorded in ca1 pyramidal neurons in rat hippocampal slices and in dissociated neurons grown in culture. |
2001-04-19 |
2023-08-12 |
rat |
| M Sun, D Dahl, D L Alko. Heterosynaptic transformation of GABAergic gating in the hippocampus and effects of carbonic anhydrase inhibition. The Journal of pharmacology and experimental therapeutics. vol 296. issue 3. 2001-03-15. PMID:11181911. |
heterosynaptic transformation of gabaergic gating in the hippocampus and effects of carbonic anhydrase inhibition. |
2001-03-15 |
2023-08-12 |
rat |
| J T Kittler, J Wang, C N Connolly, S Vicini, T G Smart, S J Mos. Analysis of GABAA receptor assembly in mammalian cell lines and hippocampal neurons using gamma 2 subunit green fluorescent protein chimeras. Molecular and cellular neurosciences. vol 16. issue 4. 2001-03-08. PMID:11085880. |
using gamma 2l-gfpn we were able to demonstrate that targeting of the gamma 2 subunit to gabaergic synapses in hippocampal neurons was dependent upon coassembly with receptor alpha and beta subunits. |
2001-03-08 |
2023-08-12 |
Not clear |
| M J Denham, R M Borisyu. A model of theta rhythm production in the septal-hippocampal system and its modulation by ascending brain stem pathways. Hippocampus. vol 10. issue 6. 2001-03-08. PMID:11153716. |
recent experimental observations have disclosed the existence of a septal-hippocampal feedback circuit, composed of medial septum diagonal band of broca (ms-dbb) gabaergic projections to the inhibitory interneurons of the hippocampus, and hippocampal gabaergic projections to the ms-dbb, the major targets of which are the gabaergic septo-hippocampal projection cells. |
2001-03-08 |
2023-08-12 |
Not clear |
| S J Pleasure, S Anderson, R Hevner, A Bagri, O Marin, D H Lowenstein, J L Rubenstei. Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron. vol 28. issue 3. 2001-03-08. PMID:11163262. |
cell migration from the ganglionic eminences is required for the development of hippocampal gabaergic interneurons. |
2001-03-08 |
2023-08-12 |
mouse |
| S J Pleasure, S Anderson, R Hevner, A Bagri, O Marin, D H Lowenstein, J L Rubenstei. Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron. vol 28. issue 3. 2001-03-08. PMID:11163262. |
gabaergic interneurons have major roles in hippocampal function and dysfunction. |
2001-03-08 |
2023-08-12 |
mouse |
| S J Pleasure, S Anderson, R Hevner, A Bagri, O Marin, D H Lowenstein, J L Rubenstei. Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron. vol 28. issue 3. 2001-03-08. PMID:11163262. |
disrupting differentiation in the embryonic basal telencephalon (lateral and medial ganglionic eminences) through loss of dlx1/2 homeobox function blocks the migration of virtually all gabaergic interneurons to the hippocampus. |
2001-03-08 |
2023-08-12 |
mouse |
| K Jensen, M S Jensen, B E Bonefeld, J D Lamber. Developmental increase in asynchronous GABA release in cultured hippocampal neurons. Neuroscience. vol 101. issue 3. 2001-03-01. PMID:11113307. |
developmental changes in gabaergic synaptic transmission were examined in cultured hippocampal neurons using patch-clamp recordings and ca(2+) imaging. |
2001-03-01 |
2023-08-12 |
Not clear |
| M Alreja, M Wu, W Liu, J B Atkins, C Leranth, M Shanabroug. Muscarinic tone sustains impulse flow in the septohippocampal GABA but not cholinergic pathway: implications for learning and memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050132. |
behavioral studies in rats have demonstrated that the medial septum/diagonal band of broca (msdb), which sends cholinergic and gabaergic projections to the hippocampus, is a critical locus in mediating the amnesic effects of atr/scop. |
2001-02-22 |
2023-08-12 |
rat |
| A Rao, E M Cha, A M Crai. Mismatched appositions of presynaptic and postsynaptic components in isolated hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 22. 2001-02-22. PMID:11069941. |
to determine whether presynaptic input is necessary for postsynaptic differentiation, we isolated hippocampal neurons in microisland culture and thus deprived pyramidal cells of gaba input and gabaergic neurons of glutamate input. |
2001-02-22 |
2023-08-12 |
Not clear |
| D Lau, E C Vega-Saenz de Miera, D Contreras, A Ozaita, M Harvey, A Chow, J L Noebels, R Paylor, J I Morgan, C S Leonard, B Rud. Impaired fast-spiking, suppressed cortical inhibition, and increased susceptibility to seizures in mice lacking Kv3.2 K+ channel proteins. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 24. 2001-02-22. PMID:11124984. |
in the brain, kv3 channels are prominently expressed in select neuronal populations, which include fast-spiking (fs) gabaergic interneurons of the neocortex, hippocampus, and caudate, as well as other high-frequency firing neurons. |
2001-02-22 |
2023-08-12 |
mouse |
| K Jensen, J D Lambert, M S Jense. The effect of internal GTPgammaS on GABA-release in cultured hippocampal neurons. Experimental brain research. vol 134. issue 2. 2001-02-15. PMID:11037287. |
the effects of presynaptic guanosine-5'-o-(3-thio)triphosphate (gtpgammas) on gabaergic inhibitory postsynaptic currents (ipscs) were studied in cultured hippocampal neurons using whole-cell recordings. |
2001-02-15 |
2023-08-12 |
Not clear |
| M Monda, A Viggiano, V De Luc. Administration of muscimol into the posterior hypothalamus reduces hyperthermia induced by hippocampal neostigmine injection. Brain research. vol 887. issue 2. 2001-02-15. PMID:11134624. |
the findings suggest that hippocampus controls the sympathetic and thermogenic activation induced by neostigmine through an influence on gabaergic tone of the posterior hypothalamus. |
2001-02-15 |
2023-08-12 |
rat |
| J E Wells, J T Porter, A Agmo. GABAergic inhibition suppresses paroxysmal network activity in the neonatal rodent hippocampus and neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102490. |
gabaergic inhibition suppresses paroxysmal network activity in the neonatal rodent hippocampus and neocortex. |
2001-02-08 |
2023-08-12 |
mouse |
| J E Wells, J T Porter, A Agmo. GABAergic inhibition suppresses paroxysmal network activity in the neonatal rodent hippocampus and neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102490. |
in contrast, we show here that when fast gabaergic neurotransmission was blocked in slices of neonatal mouse and rat hippocampus and neocortex, spfps occurred in nearly half the slices from postnatal day 4 (p4) to p7 neocortex and in most slices from p2 to p7 hippocampus. |
2001-02-08 |
2023-08-12 |
mouse |