| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jinquan Li, Yanjun Liu, Chuhui Yin, Yan Zeng, Yufei Me. Structural and functional remodeling of neural networks in β-amyloid driven hippocampal hyperactivity. Ageing research reviews. 2024-09-01. PMID:39218080. |
therefore, in this narrative review, we discuss the role of aβ-induced altered intrinsic neuronal properties as well as structural and functional remodeling of glutamatergic, gabaergic, cholinergic, noradrenergic, serotonergic circuits in hippocampal hyperactivity. |
2024-09-01 |
2024-09-04 |
Not clear |
| Joanne C Damborsky, Jerrel L Yake. Regulation of Hippocamposeptal Synaptic Transmission by GABA Journal of molecular neuroscience : MN. vol 74. issue 3. 2024-08-30. PMID:39212758. |
regulation of hippocamposeptal synaptic transmission by gaba hippocamposeptal (hs) neurons send gabaergic projections from the hippocampus to the medial septum/diagonal band of broca (ms/dbb) as part of a reciprocal loop that is critical for memory. |
2024-08-30 |
2024-09-04 |
mouse |
| Hugo R Arias, Paulina Kazmierska-Grebowska, Tomasz Kowalczyk, Yaeun Shim, Bartosz Caban, Chloé Aman, Anne-Emilie Allain, Philippe De Deurwaerdère, Abdeslam Chagraou. Coronaridine congeners induce anticonvulsant activity in rodents by hippocampal mechanisms involving mainly potentiation of GABA European journal of pharmacology. 2024-08-23. PMID:39179091. |
coronaridine congeners induce anticonvulsant activity in rodents by hippocampal mechanisms involving mainly potentiation of gaba the coronaridine congeners catharanthine and 18-methoxycoronaridine (18-mc) display sedative, anxiolytic, and antidepressant properties by acting on mechanisms involving gabaergic and/or monoaminergic transmissions. |
2024-08-23 |
2024-08-27 |
mouse |
| Adriana Jesus Souza, Ícaro Silva Freitas, Dishary Sharmin, James M Cook, Francisco S Guimarães, Felipe V Gome. An alpha 5-GABA Autism research : official journal of the International Society for Autism Research. vol 17. issue 8. 2024-08-22. PMID:39169698. |
deficits in the prefrontal and hippocampal excitatory/inhibitory balance due to a functional loss of gabaergic interneurons are proposed to underlie these symptoms. |
2024-08-22 |
2024-08-24 |
Not clear |
| Shuai Wang, Zijie Li, Xin Liu, Shiyue Fan, Xuejiao Wang, Jianjun Chang, Ling Qin, Ping Zha. Repeated postnatal sevoflurane exposure impairs social recognition in mice by disrupting GABAergic neuronal activity and development in hippocampus. British journal of anaesthesia. 2024-08-14. PMID:39142987. |
repeated postnatal sevoflurane exposure impairs social recognition in mice by disrupting gabaergic neuronal activity and development in hippocampus. |
2024-08-14 |
2024-08-17 |
mouse |
| Robert Machold, Bernardo Rud. Genetic approaches to elucidating cortical and hippocampal GABAergic interneuron diversity. Frontiers in cellular neuroscience. vol 18. 2024-08-08. PMID:39113758. |
genetic approaches to elucidating cortical and hippocampal gabaergic interneuron diversity. |
2024-08-08 |
2024-08-10 |
Not clear |
| Xiaoshan Liang, Xiaotao Liang, Yunyan Zhao, Yuewen Ding, Xiaoyu Zhu, Jieli Zhou, Jing Qiu, Xiaoqin Shen, Wei Xi. Dysregulation of the Suprachiasmatic Nucleus Disturbs the Circadian Rhythm and Aggravates Epileptic Seizures by Inducing Hippocampal GABAergic Dysfunction in C57BL/6 Mice. Journal of pineal research. vol 76. issue 5. 2024-07-26. PMID:39054842. |
dysregulation of the suprachiasmatic nucleus disturbs the circadian rhythm and aggravates epileptic seizures by inducing hippocampal gabaergic dysfunction in c57bl/6 mice. |
2024-07-26 |
2024-07-28 |
mouse |
| Xiaoshan Liang, Xiaotao Liang, Yunyan Zhao, Yuewen Ding, Xiaoyu Zhu, Jieli Zhou, Jing Qiu, Xiaoqin Shen, Wei Xi. Dysregulation of the Suprachiasmatic Nucleus Disturbs the Circadian Rhythm and Aggravates Epileptic Seizures by Inducing Hippocampal GABAergic Dysfunction in C57BL/6 Mice. Journal of pineal research. vol 76. issue 5. 2024-07-26. PMID:39054842. |
additionally, there was enhanced activation of gabaergic projections from the scn to the hippocampus. |
2024-07-26 |
2024-07-28 |
mouse |
| Xiaoshan Liang, Xiaotao Liang, Yunyan Zhao, Yuewen Ding, Xiaoyu Zhu, Jieli Zhou, Jing Qiu, Xiaoqin Shen, Wei Xi. Dysregulation of the Suprachiasmatic Nucleus Disturbs the Circadian Rhythm and Aggravates Epileptic Seizures by Inducing Hippocampal GABAergic Dysfunction in C57BL/6 Mice. Journal of pineal research. vol 76. issue 5. 2024-07-26. PMID:39054842. |
notably, scn lesions intensified seizure activity, concomitant with hippocampal neuronal damage and gabaergic signaling impairment. |
2024-07-26 |
2024-07-28 |
mouse |
| Xiaoshan Liang, Xiaotao Liang, Yunyan Zhao, Yuewen Ding, Xiaoyu Zhu, Jieli Zhou, Jing Qiu, Xiaoqin Shen, Wei Xi. Dysregulation of the Suprachiasmatic Nucleus Disturbs the Circadian Rhythm and Aggravates Epileptic Seizures by Inducing Hippocampal GABAergic Dysfunction in C57BL/6 Mice. Journal of pineal research. vol 76. issue 5. 2024-07-26. PMID:39054842. |
targeted deletion of bmal1 in scn neurons exacerbated seizures and pathology in epilepsy, as well as diminished hippocampal gabaergic efficacy. |
2024-07-26 |
2024-07-28 |
mouse |
| Xiaoshan Liang, Xiaotao Liang, Yunyan Zhao, Yuewen Ding, Xiaoyu Zhu, Jieli Zhou, Jing Qiu, Xiaoqin Shen, Wei Xi. Dysregulation of the Suprachiasmatic Nucleus Disturbs the Circadian Rhythm and Aggravates Epileptic Seizures by Inducing Hippocampal GABAergic Dysfunction in C57BL/6 Mice. Journal of pineal research. vol 76. issue 5. 2024-07-26. PMID:39054842. |
these results underscore the crucial role of the scn in modulating circadian rhythms and gabaergic function in the hippocampus, aggravating the severity of seizures. |
2024-07-26 |
2024-07-28 |
mouse |
| Guilherme Juvenal, Guilherme Shigueto Vilar Higa, Lucas Bonfim Marques, Thais Tessari Zampieri, Felipe José Costa Viana, Luiz R Britto, Yong Tang, Peter Illes, Francesco di Virgilio, Henning Ulrich, Roberto de Pasqual. Regulation of GABAergic neurotransmission by purinergic receptors in brain physiology and disease. Purinergic signalling. 2024-07-24. PMID:39046648. |
purinergic receptors timely modulate gabaergic control over ongoing neural activity and deeply affect neural processing in the hippocampal and neocortical circuitry. |
2024-07-24 |
2024-07-26 |
Not clear |
| Rahmi Lee, Gayeon Kim, Seonil Ki. Co-activation of selective nicotinic acetylcholine receptor subtypes is required to reverse hippocampal network dysfunction and prevent fear memory loss in Alzheimer's disease. bioRxiv : the preprint server for biology. 2024-07-19. PMID:39026693. |
research suggests that a reduction of gabaergic inhibitory interneurons' activity in the hippocampus by beta-amyloid peptide (aβ) is a crucial trigger for cognitive impairment in ad via hyperexcitability. |
2024-07-19 |
2024-07-21 |
mouse |
| Inês C Guerreiro, Claudia Clopat. Memory's gatekeeper: The role of PFC in the encoding of congruent events. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 30. 2024-07-17. PMID:39018188. |
more specifically, the pfc uses gabaergic long-range projections to inhibit hpc neurons representing input components correlated with a previously stored memory "schema," eliciting sparse hippocampal activity during exposure to congruent events, as it has been experimentally observed. |
2024-07-17 |
2024-07-20 |
Not clear |
| Arnulfo Tuñon-Ortiz, Dimitri Tränkner, Olivia Raines, Abbey Mahnke, Sarah Brockway, Matthew Grega, Moriel Zelikowsky, Megan E William. Inhibitory neurons defined by a synaptogenic molecule impair memory discrimination. bioRxiv : the preprint server for biology. 2024-07-16. PMID:39005261. |
here, we investigate the function of a group of dendrite-targeting, hippocampal gabaergic neurons defined by expression of the synaptogenic adhesion molecule, kirrel3. |
2024-07-16 |
2024-07-18 |
Not clear |
| Ricardo Raudales, Gukhan Kim, Sean M Kelly, Joshua Hatfield, Wuqiang Guan, Shengli Zhao, Anirban Paul, Yongjun Qian, Bo Li, Z Josh Huan. Specific and comprehensive genetic targeting reveals brain-wide distribution and synaptic input patterns of GABAergic axo-axonic interneurons. eLife. vol 13. 2024-07-16. PMID:39012795. |
axo-axonic cells (aacs), also called chandelier cells (chcs) in the cerebral cortex, are the most distinctive type of gabaergic interneurons described in the neocortex, hippocampus, and basolateral amygdala (bla). |
2024-07-16 |
2024-07-19 |
mouse |
| Kristina Lippman. A Reduction in the Readily Releasable Vesicle Pool Impairs GABAergic Inhibition in the Hippocampus after Blood-Brain Barrier Dysfunction. International journal of molecular sciences. vol 25. issue 13. 2024-07-13. PMID:38999971. |
a reduction in the readily releasable vesicle pool impairs gabaergic inhibition in the hippocampus after blood-brain barrier dysfunction. |
2024-07-13 |
2024-07-15 |
Not clear |
| Ester Orav, Bojana Kokinovic, Heidi Teppola, Mari Siimon, Sari E Lauri, Henrike Hartun. Arginine vasopressin activates serotonergic neurons in the dorsal raphe nucleus during neonatal development in vitro and in vivo. Neuropharmacology. 2024-07-12. PMID:38996832. |
in perinatal hippocampus, avp activates gabaergic interneurons which leads to suppression of spontaneous network events and suggests a protective function of avp on cortical networks during birth. |
2024-07-12 |
2024-07-15 |
rat |
| Corrigendum: MicroRNA-502-3p regulates GABAergic synapse function in hippocampal neurons. Neural regeneration research. vol 20. issue 4. 2024-07-11. PMID:38989929. |
corrigendum: microrna-502-3p regulates gabaergic synapse function in hippocampal neurons. |
2024-07-11 |
2024-07-13 |
Not clear |
| Marta Barrera-Conde, Carla Ramon-Duaso, Jose Antonio González-Parra, Emma Veza-Estevez, Vivien Chevaleyre, Rebecca A Piskorowski, Rafael de la Torre, Arnau Busquets-García, Patricia Robled. Adolescent cannabinoid exposure rescues phencyclidine-induced social deficits through modulation of CA2 transmission. Progress in neurobiology. 2024-07-02. PMID:38955325. |
using behavioral, biochemical, and electrophysiological approaches, we showed that pcp persistently reduced sociability, decreased gad67 expression in the hippocampus, and induced gabaergic deficits in proximal inputs from ca3 and distal inputs from the entorhinal cortex (ec) to ca2. |
2024-07-02 |
2024-07-06 |
mouse |