| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinxin Liu, Zixin Hou, Mingming Han, Kemin Chen, Yuxia Wang, Jie Qing, Fengrui Yan. Salvianolic acid B alleviates comorbid pain in depression induced by chronic restraint stress through inhibiting GABAergic neuron excitation via an ERK-CREB-BDNF axis-dependent mechanism. Journal of psychiatric research. vol 151. 2022-05-02. PMID:35500448. |
after treatment with salb and erk-creb-bdnf signaling pathway inhibitor, crs mice showed a variety of depression-like behaviors, accompanied by enhanced activity of gabaergic neurons in the amygdala projecting to parafascicular nucleus of thalamus. |
2022-05-02 |
2023-08-13 |
mouse |
| Xinxin Liu, Zixin Hou, Mingming Han, Kemin Chen, Yuxia Wang, Jie Qing, Fengrui Yan. Salvianolic acid B alleviates comorbid pain in depression induced by chronic restraint stress through inhibiting GABAergic neuron excitation via an ERK-CREB-BDNF axis-dependent mechanism. Journal of psychiatric research. vol 151. 2022-05-02. PMID:35500448. |
collectively, salb inhibits the excitation of gabaergic neurons in the amygdala and activates the erk-creb-bdnf signaling pathway through the parafascicular nucleus of thalamus, whereby alleviating comorbid pain in crs-induced depression in mice. |
2022-05-02 |
2023-08-13 |
mouse |
| Giancarlo Carli, Francesca Farabollin. Neuromediators and defensive responses including tonic immobility (TI): Brain areas and circuits involved. Progress in brain research. vol 271. issue 1. 2022-04-10. PMID:35397888. |
ti duration, in fact, decreases in rabbits following systemic serotonin administration and in guinea pigs following serotonin microinjection administration into the amygdala owing to the activation of fear-related gabaergic inhibitory mechanisms. |
2022-04-10 |
2023-08-13 |
human |
| Lindsey M Biggs, Michael Meredit. Functional connectivity of intercalated nucleus with medial amygdala: A circuit relevant for chemosignal processing. IBRO neuroscience reports. vol 12. 2022-02-24. PMID:35199098. |
the largely gabaergic micn receives no direct chemosensory input but, as we show, micn has functional circuit connections with medial amygdala that could be responsible both for micn chemosensitivity and for a feedforward inhibitory effect on posterior medial amygdala; which, in turn would affect chemosignal response. |
2022-02-24 |
2023-08-13 |
human |
| Xiao Zhuang, Bing Zhan, Yufeng Jia, Chaoze Li, Nan Wu, Ming Zhao, Nuo Chen, Yaxin Guo, Yingxin Du, Yi Zhang, Baihui Cao, Yan Li, Faliang Zhu, Chun Guo, Qun Wang, Yuan Li, Lining Zhan. IL-33 in the basolateral amygdala integrates neuroinflammation into anxiogenic circuits via modulating BDNF expression. Brain, behavior, and immunity. 2022-02-19. PMID:35181439. |
mechanically, il-33 suppressed bdnf expression through nf-κb pathway to impair gabaergic transmission in the amygdala and nf-κb inhibitor abolished the effect of il-33 on anxiety. |
2022-02-19 |
2023-08-13 |
mouse |
| Sara Douceau, Eloïse Lemarchand, Yannick Hommet, Laurent Lebouvier, Charlène Joséphine, Alexis-Pierre Bemelmans, Eric Maubert, Véronique Agin, Denis Vivie. PKCδ-positive GABAergic neurons in the central amygdala exhibit tissue-type plasminogen activator: role in the control of anxiety. Molecular psychiatry. 2022-02-11. PMID:35145231. |
pkcδ-positive gabaergic neurons in the central amygdala exhibit tissue-type plasminogen activator: role in the control of anxiety. |
2022-02-11 |
2023-08-13 |
mouse |
| b' R Tokunaga, Y Takahashi, S Touj, H Hotta, H Leblond, F Kato, M Pich\\xc3\\xa. Attenuation of widespread hypersensitivity to noxious mechanical stimuli by inhibition of GABAergic neurons of the right amygdala in a rat model of chronic back pain. European journal of pain (London, England). 2022-02-07. PMID:35129248.' |
attenuation of widespread hypersensitivity to noxious mechanical stimuli by inhibition of gabaergic neurons of the right amygdala in a rat model of chronic back pain. |
2022-02-07 |
2023-08-13 |
rat |
| Robert Lalonde, Catherine Straziell. Neurochemical anatomy of dorsal and tonic immobility responses. Pharmacology, biochemistry, and behavior. 2022-01-13. PMID:35026175. |
the neurochemical basis of the dir appears to pass through the basal ganglia via dopaminergic fibers, while the neurochemical basis of the tir appears to include a circuit comprising the amygdala, the periaqueductal gray (pag), the dorsal raphe, and the nucleus magnus raphe (nmr) via glutamatergic, serotonergic, cholinergic, gabaergic, and opioid fibers. |
2022-01-13 |
2023-08-13 |
Not clear |
| Alberto Marcos, Inmaculada Ballesteros-Yáñez, Carlos A Castillo-Sarmiento, Felipe Pardo, David Roura-Martínez, José Ramón Muñoz-Rodríguez, Alejandro Higuera-Matas, Emilio Ambrosi. The interactions of alcohol and cocaine regulate the expression of genes involved in the GABAergic, glutamatergic and endocannabinoid systems of male and female rats. Neuropharmacology. 2021-12-29. PMID:34965406. |
significant interactions between cocaine and alcohol were common, affecting the gabaergic and endocannabinoid systems in the medial prefrontal cortex and amygdala of young adults, whereas such interactions were evident in the glutamatergic and endocannabinoid systems in adults, as well as a more pronounced sex effect. |
2021-12-29 |
2023-08-13 |
rat |
| Laura B Tucker, Amanda H Fu, Joseph T McCab. Hippocampal-Dependent Cognitive Dysfunction following Repeated Diffuse Rotational Brain Injury in Male and Female Mice. Journal of neurotrauma. vol 38. issue 11. 2021-11-18. PMID:33622092. |
no changes in the density of gabaergic parvalbumin-expressing cells in the hippocampus, amygdala, or parietal cortex were found. |
2021-11-18 |
2023-08-13 |
mouse |
| Viktória K Vereczki, Kinga Müller, Éva Krizsán, Zoltán Máté, Zsuzsanna Fekete, Laura Rovira-Esteban, Judit M Veres, Ferenc Erdélyi, Norbert Hájo. Total Number and Ratio of GABAergic Neuron Types in the Mouse Lateral and Basal Amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 21. 2021-11-18. PMID:33837051. |
despite growing evidence showing that inhibitory cells play a critical role in the lateral (la) and basal (ba) amygdala functions, neither the number of gabaergic neurons nor the ratio of their distinct types has been determined in these amygdalar nuclei. |
2021-11-18 |
2023-08-13 |
mouse |
| Ming Chen, Ying Li, Ying Liu, Haibo Xu, Lin-Lin B. Neuregulin-1-dependent control of amygdala microcircuits is critical for fear extinction. Neuropharmacology. vol 201. 2021-11-09. PMID:34678375. |
the nrg1-erbb4 pathway in the itc did not affect excitatory input to itc neurons from bla neurons but increased feed-forward inhibition of (the central medial nucleus of the amygdala) cem neurons through increased gabaergic neurotransmission of itc neurons. |
2021-11-09 |
2023-08-13 |
Not clear |
| Matthew N Tran, Kristen R Maynard, Abby Spangler, Louise A Huuki, Kelsey D Montgomery, Vijay Sadashivaiah, Madhavi Tippani, Brianna K Barry, Dana B Hancock, Stephanie C Hicks, Joel E Kleinman, Thomas M Hyde, Leonardo Collado-Torres, Andrew E Jaffe, Keri Martinowic. Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain. Neuron. vol 109. issue 19. 2021-10-25. PMID:34582785. |
we first identified novel subpopulations of interneurons and medium spiny neurons (msns) in the nucleus accumbens and further characterized robust gabaergic inhibitory cell populations in the amygdala. |
2021-10-25 |
2023-08-13 |
human |
| Dean Kirson, Michael Q Steinman, Sarah A Wolfe, Samantha R Spierling Bagsic, Michal Bajo, Suhas Sureshchandra, Christopher S Oleata, Ilhem Messaoudi, Eric P Zorrilla, Marisa Robert. Sex and context differences in the effects of trauma on comorbid alcohol use and post-traumatic stress phenotypes in actively drinking rats. Journal of neuroscience research. 2021-10-23. PMID:34687080. |
rats in the model had altered spontaneous action potential-independent gabaergic transmission in the central amygdala (cea), a brain region key in alcohol dependence and stress-related signaling. |
2021-10-23 |
2023-08-13 |
rat |
| Jonas Englund, Joni Haikonen, Vasilii Shteinikov, Shyrley Paola Amarilla, Tsvetomira Atanasova, Alexandra Shintyapina, Maria Ryazantseva, Juha Partanen, Vootele Voikar, Sari E Laur. Downregulation of kainate receptors regulating GABAergic transmission in amygdala after early life stress is associated with anxiety-like behavior in rodents. Translational psychiatry. vol 11. issue 1. 2021-10-22. PMID:34663781. |
downregulation of kainate receptors regulating gabaergic transmission in amygdala after early life stress is associated with anxiety-like behavior in rodents. |
2021-10-22 |
2023-08-13 |
rat |
| Jonas Englund, Joni Haikonen, Vasilii Shteinikov, Shyrley Paola Amarilla, Tsvetomira Atanasova, Alexandra Shintyapina, Maria Ryazantseva, Juha Partanen, Vootele Voikar, Sari E Laur. Downregulation of kainate receptors regulating GABAergic transmission in amygdala after early life stress is associated with anxiety-like behavior in rodents. Translational psychiatry. vol 11. issue 1. 2021-10-22. PMID:34663781. |
gabaergic microcircuits in the amygdala are critically implicated in anxiety; however, whether their function is altered after els is not known. |
2021-10-22 |
2023-08-13 |
rat |
| Jonas Englund, Joni Haikonen, Vasilii Shteinikov, Shyrley Paola Amarilla, Tsvetomira Atanasova, Alexandra Shintyapina, Maria Ryazantseva, Juha Partanen, Vootele Voikar, Sari E Laur. Downregulation of kainate receptors regulating GABAergic transmission in amygdala after early life stress is associated with anxiety-like behavior in rodents. Translational psychiatry. vol 11. issue 1. 2021-10-22. PMID:34663781. |
inactivation of grik1 expression locally in the adult amygdala reduced ongoing gabaergic transmission and was sufficient to produce a mild anxiety-like behavioral phenotype. |
2021-10-22 |
2023-08-13 |
rat |
| Ayla Aksoy-Aksel, Andrea Gall, Anna Seewald, Francesco Ferraguti, Ingrid Ehrlic. Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms in male mice. eLife. vol 10. 2021-10-18. PMID:34028352. |
within the amygdala, gabaergic intercalated cell (itc) clusters receive one of the densest dopaminergic projections, but their physiological consequences are incompletely understood. |
2021-10-18 |
2023-08-13 |
mouse |
| Michael Q Steinman, Dean Kirson, Sarah A Wolfe, Sophia Khom, Shannon R D'Ambrosio, Samantha R Spierling Bagsic, Michal Bajo, Roman Vlkolinský, Noah K Hoang, Anshita Singhal, Suhas Sureshchandra, Christopher S Oleata, Ilhem Messaoudi, Eric P Zorrilla, Marisa Robert. Importance of sex and trauma context on circulating cytokines and amygdalar GABAergic signaling in a comorbid model of posttraumatic stress and alcohol use disorders. Molecular psychiatry. vol 26. issue 7. 2021-10-15. PMID:33087855. |
during subsequent abstinence, ptsd-like behavior responses, gabaergic synaptic transmission in the central amygdala (cea), and circulating cytokine levels were measured. |
2021-10-15 |
2023-08-13 |
rat |
| Mukesh Kumar Varshney, Nancy Yiu-Lin Yu, Shintaro Katayama, Xin Li, Tianyao Liu, Wan-Fu Wu, Virpi Töhönen, Kaarel Krjutškov, Juha Kere, Xiaotang Fan, José Inzunza, Jan-Åke Gustafsson, Ivan Nalvart. Motor Function Deficits in the Estrogen Receptor Beta Knockout Mouse: Role on Excitatory Neurotransmission and Myelination in the Motor Cortex. Neuroendocrinology. vol 111. issue 1-2. 2021-10-04. PMID:31991411. |
male estrogen receptor beta (erβ) knockout (berko) mice display anxiety and aggression linked to, among others, altered serotonergic signaling in the basolateral amygdala and dorsal raphe, impaired cortical radial glia migration, and reduced gabaergic signaling. |
2021-10-04 |
2023-08-13 |
mouse |