| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Nagesh Babu, Manjeet Gupta, Vimal K Paliwal, Suruchi Singh, Tanushri Chatterji, Raja Ro. Serum metabolomics study in a group of Parkinson's disease patients from northern India. Clinica chimica acta; international journal of clinical chemistry. vol 480. 2018-10-01. PMID:29474999. |
parkinson's disease (pd) is the result of progressive degeneration of the nigrostriatal dopaminergic pathway and depletion of neurotransmitter dopamine in the striatum. |
2018-10-01 |
2023-08-13 |
Not clear |
| Francisco Zafra, Ignacio Ibáñez, David Bartolomé-Martín, Dolores Piniella, Marina Arribas-Blázquez, Cecilio Giméne. Glycine Transporters and Its Coupling with NMDA Receptors. Advances in neurobiology. vol 16. 2018-09-25. PMID:28828606. |
physiologically, glyt1 is a central actor in the cross talk between glutamatergic, glycinergic, dopaminergic, and probably other neurotransmitter systems. |
2018-09-25 |
2023-08-13 |
Not clear |
| Thomas McLaughlin, Kenneth Blum, Bruce Steinberg, Edward J Modestino, Lyle Fried, David Baron, David Siwicki, Eric R Braverman, Rajendra D Badgaiya. Pro-dopamine regulator, KB220Z, attenuates hoarding and shopping behavior in a female, diagnosed with SUD and ADHD. Journal of behavioral addictions. vol 7. issue 1. 2018-09-04. PMID:29316800. |
background addictive-like behaviors (e.g., hoarding and shopping) may be the result of the cumulative effects of dopaminergic and other neurotransmitter genetic variants as well as elevated stress levels. |
2018-09-04 |
2023-08-13 |
human |
| Jasem Estakhr, Danya Abazari, Kaitlyn Frisby, J Michael McIntosh, Raad Nashm. Differential Control of Dopaminergic Excitability and Locomotion by Cholinergic Inputs in Mouse Substantia Nigra. Current biology : CB. vol 27. issue 13. 2018-07-31. PMID:28648825. |
understanding how dopaminergic (da) neurons of the substantia nigra pars compacta (snc) govern movements requires a detailed knowledge of how different neurotransmitter systems modulate da neuronal excitability. |
2018-07-31 |
2023-08-13 |
mouse |
| Kinga Kamińska, Tomasz Lenda, Jolanta Konieczny, Anna Czarnecka, Elżbieta Lorenc-Koc. Depressive-like neurochemical and behavioral markers of Parkinson's disease after 6-OHDA administered unilaterally to the rat medial forebrain bundle. Pharmacological reports : PR. vol 69. issue 5. 2018-07-30. PMID:28843848. |
although parkinson's disease (pd) is characterized by progressive neurodegeneration of multiple neurotransmitter systems, 6-hydroxydopamine (6-ohda) as a model substance is mainly used to selectively damage the nigrostriatal dopaminergic neurons and induce parkinsonian-like motor disturbances in rats. |
2018-07-30 |
2023-08-13 |
rat |
| Kumaresan Jayaraman, Alex N Morley, Daniel Szöllősi, Tsjerk A Wassenaar, Harald H Sitte, Thomas Stockne. Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain. PLoS computational biology. vol 14. issue 6. 2018-07-13. PMID:29874235. |
the human dopamine transporter (hdat) is located on presynaptic neurons, where it plays an essential role in limiting dopaminergic signaling by temporarily curtailing high neurotransmitter concentration through rapid re-uptake. |
2018-07-13 |
2023-08-13 |
human |
| Haifeng Qian, Guangfu Liu, Tao Lu, Liwei Su. Developmental neurotoxicity of Microcystis aeruginosa in the early life stages of zebrafish. Ecotoxicology and environmental safety. vol 151. 2018-06-08. PMID:29304416. |
these results demonstrated that microcystis aeruginosa exposure affected cholinergic and dopaminergic neurotransmitter systems, the transcription of key nervous system genes, and consequently the activity level of larval zebrafish. |
2018-06-08 |
2023-08-13 |
zebrafish |
| Elsa Lindgren, Kyle Gray, Gregg Miller, Ryan Tyler, Corinde E Wiers, Nora D Volkow, Gene-Jack Wan. Food addiction: A common neurobiological mechanism with drug abuse. Frontiers in bioscience (Landmark edition). vol 23. 2018-06-01. PMID:28930574. |
we examine not only functional and structural changes in the mesolimbic pathways, but also in other frontal areas shown to be involved in drug addiction, including the prefrontal cortex, orbitofrontal cortex and anterior cingulate cortex, as well as changes in neurotransmitter systems beyond dopaminergic systems. |
2018-06-01 |
2023-08-13 |
Not clear |
| Luke A Downey, Brenda Tysse, Talitha C Ford, Angela C Samuels, Rory P Wilson, Andrew C Parrot. Psychomotor Tremor and Proprioceptive Control Problems in Current and Former Stimulant Drug Users: An Accelerometer Study of Heavy Users of Amphetamine, MDMA, and Other Recreational Stimulants. Journal of clinical pharmacology. vol 57. issue 10. 2018-05-31. PMID:28425095. |
the recreational use of various stimulant drugs has been implicated in the development of movement disorders through dysregulation of the dopaminergic and serotoninergic neurotransmitter systems. |
2018-05-31 |
2023-08-13 |
human |
| Dongxu Gao, Chonggang Wang, Zhihui Xi, Yixi Zhou, Yuanchuan Wang, Zhenghong Zu. Early-Life Benzo[a]Pyrene Exposure Causes Neurodegenerative Syndromes in Adult Zebrafish (Danio rerio) and the Mechanism Involved. Toxicological sciences : an official journal of the Society of Toxicology. vol 157. issue 1. 2018-05-02. PMID:28329817. |
we found that bap decreased locomotor and cognitive ability, neurotransmitter levels of dopamine, 3,4-dihydroxyphenylacetic acid and norepinephrine; and induced loss of dopaminergic neurons and resulted in neurodegeneration. |
2018-05-02 |
2023-08-13 |
zebrafish |
| Dorit Ben-Shacha. Mitochondrial multifaceted dysfunction in schizophrenia; complex I as a possible pathological target. Schizophrenia research. vol 187. 2018-04-30. PMID:27802911. |
schizophrenia is currently regarded as a neurodevelopmental disorder associated with impaired immune system, aberrant neuronal differentiation and abnormalities in various neurotransmitter systems mainly the dopaminergic, glutaminergic and gabaergic. |
2018-04-30 |
2023-08-13 |
Not clear |
| Lawrence M Carey, Remington J Rice, Adam J Pru. The Neurotensin NTS Drug development research. vol 78. issue 5. 2018-04-24. PMID:28736839. |
the neurotensin nts preclinical research neurotensin is a nonbrain penetrant neuropeptide neurotransmitter that alters dopaminergic and serotonergic neurotransmission. |
2018-04-24 |
2023-08-13 |
Not clear |
| Flavia Maria Sutera, Libero Italo Giannola, Denise Murgia, Viviana De Car. Assessment of in vivo organ-uptake and in silico prediction of CYP mediated metabolism of DA-Phen, a new dopaminergic agent. Computational biology and chemistry. vol 71. 2018-04-23. PMID:28985485. |
as a consequence, it is possible to assume that da-phen acts as dopaminergic modulator per se and not as a dopamine prodrug, thus avoiding peripheral release and toxic side effects due to the endogenous neurotransmitter. |
2018-04-23 |
2023-08-13 |
human |
| James P Kesby, Julia A Najera, Benedetto Romoli, Yiding Fang, Liana Basova, Amanda Birmingham, Maria Cecilia G Marcondes, Davide Dulcis, Svetlana Semenov. HIV-1 TAT protein enhances sensitization to methamphetamine by affecting dopaminergic function. Brain, behavior, and immunity. vol 65. 2018-04-10. PMID:28495611. |
activity-dependent neurotransmitter switching of a reserve pool of non-dopaminergic neurons to a dopaminergic phenotype in the ventral tegmental area (vta) was determined by immunohistochemistry and quantified with stereology. |
2018-04-10 |
2023-08-13 |
mouse |
| Yanhui Chen, Xiaolan Zheng, Linqi Xie, Liang Huang, Zhongling Ke, Jie Zheng, Hongzhu Lu, Jun H. Glucocorticoids/glucocorticoid receptors effect on dopaminergic neurotransmitters in ADHD rats. Brain research bulletin. vol 131. 2018-04-09. PMID:28458039. |
our results suggest that the effects of glucocorticoid receptor on dopaminergic neurotransmitter in the central nervous system may be involved in the pathogenesis of adhd. |
2018-04-09 |
2023-08-13 |
rat |
| Annadurai Anandhan, Maria S Jacome, Shulei Lei, Pablo Hernandez-Franco, Aglaia Pappa, Mihalis I Panayiotidis, Robert Powers, Rodrigo Franc. Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism. Brain research bulletin. vol 133. 2018-03-30. PMID:28341600. |
alterations in redox homeostasis and bioenergetics (energy failure) are thought to be central components of neurodegeneration that contribute to the impairment of important homeostatic processes in dopaminergic cells such as protein quality control mechanisms, neurotransmitter release/metabolism, axonal transport of vesicles and cell survival. |
2018-03-30 |
2023-08-13 |
Not clear |
| F S Oluwole, C Onwuchekw. Zinc salt enhances gastroprotective activity of risperidone in indomethacin-induced gastric ulcer. African journal of medicine and medical sciences. vol 45. issue 3. 2018-03-27. PMID:29462535. |
risperidone as an antipsychotic drug blocks several neurotransmitter systems including dopaminergic, adrenergic, histaminergic and serotonergic pathways. |
2018-03-27 |
2023-08-13 |
Not clear |
| David J Heal, Michelle Hallam, Michael Prow, Jane Gosden, Sharon Cheetham, Yong K Choi, Frank Tarazi, Peter Hutso. Dopamine and μ-opioid receptor dysregulation in the brains of binge-eating female rats - possible relevance in the psychopathology and treatment of binge-eating disorder. Journal of psychopharmacology (Oxford, England). vol 31. issue 6. 2018-03-22. PMID:28376679. |
we investigated whether (a) dysregulated central nervous system dopaminergic and opioidergic systems are part of the psychopathology of binge-eating and (b) these neurotransmitter systems may mediate the actions of drugs ameliorating binge-eating disorder psychopathology. |
2018-03-22 |
2023-08-13 |
rat |
| Marta Karpinski, Gabriella Francesca Mattina, Meir Steine. Effect of Gonadal Hormones on Neurotransmitters Implicated in the Pathophysiology of Obsessive-Compulsive Disorder: A Critical Review. Neuroendocrinology. vol 105. issue 1. 2018-03-21. PMID:27894107. |
in turn, investigations into neurotransmission in oc individuals have been more extensive, and have implicated the serotonergic, dopaminergic, and glutamatergic neurotransmitter systems in ocd pathology. |
2018-03-21 |
2023-08-13 |
Not clear |
| E V Kur'yanova, A V Tryasuchev, V O Stupin, D L Teply. Effect of Stimulation of Neurotransmitter Systems on Heart Rate Variability and β-Adrenergic Responsiveness of Erythrocytes in Outbred Rats. Bulletin of experimental biology and medicine. vol 163. issue 1. 2018-03-19. PMID:28577106. |
we studied heart rate variability and β-adrenergic responsiveness of erythrocytes and changes in these parameters in response to single administration of β-adrenoblocker propranolol (2 mg/kg) in outbred male rats against the background of activation of the noradrenergic, serotonergic, and dopaminergic neurotransmitter systems achieved by 4-fold injections maprotiline (10 mg/kg), 5-hydroxytryptophan (50 mg/kg) combined with fluoxetine (3 mg/kg), and l-dopa (20 mg/kg) with amantadine (20 mg/kg), respectively. |
2018-03-19 |
2023-08-13 |
rat |