| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Lewiński, J Konopacki, M Pawlikowski, M K Lewińska, N K Smith, R J Reite. Effects of intraventricular injections of 6-hydroxydopamine on anterior pituitary cell proliferation. The Anatomical record. vol 208. issue 3. 1984-06-14. PMID:6426346. |
the low mmars at 48 hours after 6-ohda injection are probably a result of dopamine release from damaged nerve endings; the enhancement of mmars (particularly evident in the 6-ohda + dmi-treated group) at 96 and 144 hours after drug administration is presumably related to a deficiency of dopaminergic control of anterior pituitary cell proliferation. |
1984-06-14 |
2023-08-12 |
rat |
| D H Versteeg, D Van Heuven-Nolsen, D De Wie. Pre-decapitation state of arousal of rats predetermines the effect of des-Tyr1-gamma-endorphin on dopamine release from nucleus accumbens slices in vitro. Life sciences. vol 34. issue 16. 1984-06-14. PMID:6717245. |
exposure of rats to ether vapor shortly before decapitation abolished both these in vitro effects of dt gamma e. the results are interpreted as indicating that the quality of the modulating effects of dt gamma e on dopamine release from dopaminergic neurons projecting to the nucleus accumbens is depending on the state of activity of these neurons, which, in its turn, is a reflection of the state of arousal of the rats. |
1984-06-14 |
2023-08-12 |
rat |
| M Miyamoto, S Narumi, Y Nagai, Y Saji, Y Nagaw. A TRH analog (DN-1417): motor stimulation with rearing related to catecholaminergic mechanisms in rats. Neuropharmacology. vol 23. issue 1. 1984-06-07. PMID:6425711. |
these findings indicate that the motor stimulatory action of dn-1417 appears to be mediated primarily via a dopaminergic mechanism by enhancing the release of dopamine from nerve terminals, including the nucleus accumbens in the mesolimbic dopamine system, and, in turn, the rearing may be mediated via noradrenergic mechanism. |
1984-06-07 |
2023-08-12 |
rat |
| P Linnestad, I Guldvog, E Schrump. Effects of dopamine and dopamine antagonists on postprandial release of pancreatic polypeptide in dogs and in healthy volunteers. Scandinavian journal of gastroenterology. vol 18. issue 1. 1984-05-30. PMID:6144173. |
it is concluded that dopamine inhibits postprandial pp release via both dopaminergic and adrenergic receptors. |
1984-05-30 |
2023-08-12 |
human |
| E H Lee, M A Geye. Indirect effects of apomorphine on serotoninergic neurons in rats. Neuroscience. vol 11. issue 2. 1984-05-30. PMID:6201781. |
the above results suggest that the observed effects of apomorphine on the serotoninergic system are mediated indirectly through dopaminergic neurons and that postsynaptic dopamine receptors are probably not responsible for apomorphine's effects. |
1984-05-30 |
2023-08-12 |
rat |
| S L Saunders, S H Shin, C W Reife. Cysteamine acts immediately to inhibit prolactin release and induce cellular changes in estradiol-primed male rats. Neuroendocrinology. vol 38. issue 3. 1984-05-30. PMID:6325979. |
blocking the dopamine receptors with pimozide did not result in increased prl levels, indicating that csh was acting through some mechanism not directly involving dopaminergic pif receptors. |
1984-05-30 |
2023-08-12 |
rat |
| M P Martres, P Sokoloff, J C Schwart. Dopaminergic binding sites in rat striatal slices and the action of guanyl nucleotides. Naunyn-Schmiedeberg's archives of pharmacology. vol 325. issue 2. 1984-05-30. PMID:6717609. |
these observations, together with those indicating the presence of high affinity binding sites for dopaminergic agonists in intact striatal cells, suggest that a putative nucleotide regulatory unit of dopamine receptors, is not fully occupied by intracellular gtp but could be interacted with from the external face of the cell membrane. |
1984-05-30 |
2023-08-12 |
rat |
| D B Calne, K Burton, J Beckman, W R Marti. Dopamine agonists in Parkinson's disease. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 11. issue 1 Suppl. 1984-05-29. PMID:6231979. |
dopamine agonists have yielded two important advances to our understanding of the basal ganglia--they have facilitated the subdivision of different classes of dopamine receptors, and they have established the fact that important dopaminergic effects can be achieved by activation of dopamine receptors in a manner that is unrelated to anoxal impulse traffic in dopaminergic neurons--a phenomenon similar in its diffuse, slow, characteristics to an endocrine effect. |
1984-05-29 |
2023-08-12 |
Not clear |
| A Chéramy, R Romo, G Godeheu, J Glowinsk. Effects of electrical stimulation of various midline thalamic nuclei on the bilateral release of dopamine from dendrites and nerve terminals of neurons in the nigro-striatal dopaminergic pathways. Neuroscience letters. vol 44. issue 2. 1984-05-24. PMID:6709234. |
effects of electrical stimulation of various midline thalamic nuclei on the bilateral release of dopamine from dendrites and nerve terminals of neurons in the nigro-striatal dopaminergic pathways. |
1984-05-24 |
2023-08-12 |
Not clear |
| G Karakiulakis, A G Paradelis, P G Papaioannidou, P J Thoma. Maturational aspects of the dopaminergic system: ontogenesis of high affinity dopamine binding to neural membrane fragments of the rat brain. Methods and findings in experimental and clinical pharmacology. vol 5. issue 10. 1984-05-22. PMID:6672486. |
maturational aspects of the dopaminergic system: ontogenesis of high affinity dopamine binding to neural membrane fragments of the rat brain. |
1984-05-22 |
2023-08-12 |
rat |
| Z P Kometiani, L G Tsakadze, Jariashvili TY. Functional significance of the effects of neurotransmitters on the Na+,K+-ATPase system. Journal of neurochemistry. vol 42. issue 5. 1984-05-17. PMID:6142922. |
it is shown that dopamine at low concentrations specifically inhibits the na+,k+-atpase of synaptic membranes from the brain regions rich in dopaminergic endings, but has no effect on the synaptosomal na+,k+-atpase from the other parts of brain. |
1984-05-17 |
2023-08-12 |
rat |
| W L Collier, C Cavallotti, M de Rossi, F Ament. Dopamine-sensitive adenylate cyclase in rabbit renal artery. Neuroscience letters. vol 43. issue 2-3. 1984-05-11. PMID:6324039. |
the stimulation of camp levels elicited by dopamine was remarkably reduced by the dopamine receptor antagonists fluphenazine and haloperidol, but it was unaffected by the ergot-like dopaminergic agonist bromocriptine. |
1984-05-11 |
2023-08-12 |
rabbit |
| D Becú de Villalobos, M I Vacas, D P Cardinali, C Libertu. A developmental study of adenohypophyseal dopaminergic receptors and of haloperidol-induced prolactin release in rats. Brain research. vol 314. issue 2. 1984-05-10. PMID:6423213. |
the ontogenesis of adenohypophyseal dopamine receptors, assessed by haloperidol-displaceable [3h]didydroergocryptine (dhe) binding of 1-, 12-, 20-, 28-day-old female rats was studied in correlation with the prolactin releasing effect of haloperidol (1 mg/kg), a dopaminergic antagonist. |
1984-05-10 |
2023-08-12 |
rat |
| D M Ackerman, J P Hieble, H M Sarau, T C Jai. Pharmacological characterization of dopamine-4-O-sulfate. Archives internationales de pharmacodynamie et de therapie. vol 267. issue 2. 1984-05-10. PMID:6712357. |
in all the above tests, the activity of da-4-s was much weaker than dopamine, showing this metabolite has little intrinsic dopaminergic or adrenergic pharmacological activity. |
1984-05-10 |
2023-08-12 |
dog |
| S Govoni, L Lucchi, F Battaini, P F Spano, M Trabucch. Chronic lead treatment affects dopaminergic control of prolactin secretion in rat pituitary. Toxicology letters. vol 20. issue 3. 1984-04-19. PMID:6701910. |
the effect of lead exposure on dopaminergic mechanisms regulating prolactin (prl) secretion was studied in rats by measuring dopamine (da) and dihydroxyphenylacetic acid hypothalamic concentrations and da receptor density in the hypothalamus and pituitary of lead-exposed animals. |
1984-04-19 |
2023-08-12 |
rat |
| P R Martin, M H Ebert, E K Gordon, M Linnoila, I J Kopi. Effects of clonidine on central and peripheral catecholamine metabolism. Clinical pharmacology and therapeutics. vol 35. issue 3. 1984-04-17. PMID:6199153. |
changes in central noradrenergic and dopaminergic activity correlated inversely; thus diminished ne release and enhanced dopamine metabolism may both contribute to the effects of clonidine in man. |
1984-04-17 |
2023-08-12 |
Not clear |
| H Kawabe, K Kondo, T Sarut. Effect of the intracerebroventricular injection of dopamine on blood pressure in the spontaneously hypertensive rat. Clinical and experimental hypertension. Part A, Theory and practice. vol 5. issue 10. 1984-04-16. PMID:6667557. |
to examine the role of the central dopaminergic system in blood pressure regulation, dopamine was injected into the cerebral lateral ventricles of conscious, unrestrained spontaneously hypertensive rats (shr), deoxycorticosterone (doc)-salt hypertensive rats and wistar-kyoto normotensive rats (wky). |
1984-04-16 |
2023-08-12 |
rat |
| E Scarazzati, G Catenazzo, C F Melloni, P Ghirardi, L Bianc. [Preliminary evaluation of the effect of ibopamine on the secretion of prolactin]. Bollettino della Societa italiana di biologia sperimentale. vol 59. issue 11. 1984-04-06. PMID:6667307. |
ibopamine, diisobutyric ester of n-methyl dopamine, is an orally active dopaminergic agonist. |
1984-04-06 |
2023-08-12 |
human |
| T S Elizan, J Casal. The viral hypothesis in parkinsonism. Journal of neural transmission. Supplementum. vol 19. 1984-04-04. PMID:6583315. |
since carlsson's original suggestion that dopamine may be a transmitter in the central nervous system involved in the control of motor function and that it may be involved in the parkinsonian syndrome (carlsson, 1959), and the now-classic paper by ehringer and hornykiewicz (1960) which definitively showed the significant reduction of dopamine concentration in the neostriatum of cases of idiopathic parkinson and postencephalitic parkinsonism, the vast amount of work on the subject has focused on the biochemical and pharmacologic correlates of this dopaminergic system failure involving particularly the nigrostriatal pathways. |
1984-04-04 |
2023-08-12 |
human |
| H Kuribar. Strain differences to the effects of apomorphine on Sidman avoidance response and motor activity in the Wistar and F344/DuCrj (Fischer) rats. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 3. issue 1. 1984-03-23. PMID:6666376. |
the effects of apomorphine hcl (apm), a direct dopamine agonist, on sidman avoidance response (response-shock interval = 30 see and shock-shock interval = 5 sec) and on motor activity in wistar and f344/ducrj (fischer) male rats were examined to investigate the role of dopaminergic systems in differences between the two strains. |
1984-03-23 |
2023-08-12 |
rat |