| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C B Nemeroff, C D Kilts, B Levant, G Bissette, A Campbell, R J Baldessarin. Effects of the isomers of N-n-propylnorapomorphine and haloperidol on regional concentrations of neurotensin in rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 4. issue 1. 1991-04-22. PMID:1672249. |
s(+)npa, which has some properties as a limbic-selective dopamine antagonist, yielded smaller (55%-66%) but significant average increases of nt in accumbens and piriform cortex, and lesser trends toward increases (40%-51%) in caudate, nigra, and mesoprefrontal cortex--all persisting for 5 days after treatment, whereas the r(-) enantiomer, a potent dopaminergic agonist, increased nt only in nigra (by 112%). |
1991-04-22 |
2023-08-11 |
rat |
| A J Heritc. Evidence for reduced and dysregulated turnover of dopamine in schizophrenia. Schizophrenia bulletin. vol 16. issue 4. 1991-04-19. PMID:2077638. |
the dopamine (da) hypothesis of schizophrenia proposes that schizophrenia is related to dopaminergic hyperactivity. |
1991-04-19 |
2023-08-11 |
Not clear |
| N Berretta, F Berton, R Bianchi, M Capogna, W Francesconi, M Brunell. Effects of dopamine, D-1 and D-2 dopaminergic agonists on the excitability of hippocampal CA1 pyramidal cells in guinea pig. Experimental brain research. vol 83. issue 1. 1991-04-16. PMID:1981561. |
effects of dopamine, d-1 and d-2 dopaminergic agonists on the excitability of hippocampal ca1 pyramidal cells in guinea pig. |
1991-04-16 |
2023-08-11 |
Not clear |
| J De Keyser, J P De Backer, G Vauquelin, G Ebinge. D1 and D2 dopamine receptors in human substantia nigra: localization and the effect of aging. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:1825842. |
since nigrostriatal dopaminergic neurons degenerate with aging, these results suggest either that the nigral d2 receptors are up-regulated in response to a progressive depletion of dopamine in the substantia nigra or that, in contrast to the rat, they are not located on dopaminergic neurons. |
1991-04-15 |
2023-08-11 |
human |
| M S Benedetti, P Dostert, D Barone, C Efthymiopoulos, G Peretti, R Roncucc. In vivo interaction of cabergoline with rat brain dopamine receptors labelled with [3H]N-n-propylnorapomorphine. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:1981553. |
cabergoline is a potent dopaminergic agent that interacts with agonists and antagonists of dopamine receptors in vitro. |
1991-04-15 |
2023-08-11 |
rat |
| S L Greenspan, A Klibanski, J W Rowe, D Elah. Age-related alterations in pulsatile secretion of TSH: role of dopaminergic regulation. The American journal of physiology. vol 260. issue 3 Pt 1. 1991-04-12. PMID:1900670. |
to investigate the influence of aging on dopaminergic modulation of pulsatile thyrotropin (tsh) secretion, we examined changes in circulating tsh levels during the day and night, with and without a dopamine antagonist metoclopramide, in healthy young (20-35 yr old) and old (69-83 yr old) subjects, with the use of cluster analysis. |
1991-04-12 |
2023-08-11 |
human |
| T S Rao, J A Cler, S J Mick, V M Dilworth, P C Contreras, S Iyengar, P L Woo. Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:1963476. |
irreversible inactivation of dopamine receptors by eedq (n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline) did not affect the opipramol-induced increases in levels of dihydroxyphenylacetic acid (dopac) in the striatum of the rat, indicating a predominant role of activation of sigma receptors in the dopaminergic effects of opipramol. |
1991-04-09 |
2023-08-11 |
mouse |
| A Vaccari, E Stefanini, G de Montis, Z L Rossett. Dopaminergic dysfunction in neonatal hypothyroidism: differential effects of GM1 ganglioside. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:2149873. |
the ganglioside-driven selective recovery of the transport and storage process of [3h]dopamine might result either from a chronically-exerted stimulation by gm1 on the na/k- and mg-atpase activities, thus reflecting on the atpase-dependent neuronal and vesicular transport processes of dopamine or from a gm1-promoted maturation of the otherwise retarded functionality of dopaminergic nerve endings in the neonatal hypothyroid striatum. |
1991-04-09 |
2023-08-11 |
rat |
| J P Miell, R Corder, F P Pralong, R C Gaillar. Effects of dexamethasone on growth hormone (GH)-releasing hormone, arginine- and dopaminergic stimulated GH secretion, and total plasma insulin-like growth factor-I concentrations in normal male volunteers. The Journal of clinical endocrinology and metabolism. vol 72. issue 3. 1991-04-02. PMID:1671785. |
after dex administration, responses to both dopaminergic agents were suppressed [cv, 6.7 (4.0-21.2); p less than 0.01 vs. control response; and dopamine, 5.3 (4.8-7.9); p less than 0.05 vs. control response]. |
1991-04-02 |
2023-08-11 |
human |
| N E Goeders, O J Bienvenu, E B De Souz. Chronic cocaine administration alters corticotropin-releasing factor receptors in the rat brain. Brain research. vol 531. issue 1-2. 1991-04-01. PMID:1963104. |
dopamine may also be involved in the release of crf in the rat brain since the purported loss of dopaminergic innervations resulted in increased crf binding in the saline-treated animals. |
1991-04-01 |
2023-08-11 |
rat |
| C De Landsheere, D Lamott. [Methods and clinical applications of positron emission tomography in endocrinology]. Annales d'endocrinologie. vol 51. issue 3-4. 1991-04-01. PMID:2291630. |
these last tumors represent a particular entity because of several combined characteristics: high turnover rate of amino acids, high density of dopaminergic receptors and response to bromocriptine (analogue of dopamine inhibiting the secretion of prolactin) in relation to the level of receptors. |
1991-04-01 |
2023-08-11 |
Not clear |
| N Cuenca, E Fernández, H Kol. Distribution of immunoreactivity to protein kinase C in the turtle retina. Brain research. vol 532. issue 1-2. 1991-03-21. PMID:2282521. |
incubation with dopamine, in particular, brings out the putative dopaminergic amacrine cell. |
1991-03-21 |
2023-08-11 |
Not clear |
| G L Bernardini, S G Speciale, D C Germa. Increased midbrain dopaminergic cell activity following 2'CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study. Brain research. vol 527. issue 1. 1991-03-19. PMID:1980838. |
several days after the administration of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'ch3-mptp) to the balb/cj mouse there is a loss of midbrain dopaminergic neurons, a reduction of forebrain dopamine (da) content, and an elevation in forebrain da turnover. |
1991-03-19 |
2023-08-11 |
mouse |
| P A Kempster, J P Frankel, G M Stern, A J Lee. Comparison of motor response to apomorphine and levodopa in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 53. issue 11. 1991-03-18. PMID:2283512. |
these clinical observations support the notion that integrity of striatal post-synaptic dopamine receptors is a key determinant of responsiveness to dopaminergic treatment in parkinson's disease. |
1991-03-18 |
2023-08-11 |
Not clear |
| M N Castel, A Boireau, P M Laduro. Effect of gamma-butyrolactone on the retrograde axonal transport of neurotensin in dopaminergic neurones. European journal of pharmacology. vol 186. issue 1. 1991-03-15. PMID:1704309. |
gamma-butyrolactone is a drug known to inhibit the flow of electrical impulses in dopaminergic neurones and to prevent dopamine release in the striatum. |
1991-03-15 |
2023-08-11 |
rat |
| M N Castel, A Boireau, P M Laduro. Effect of gamma-butyrolactone on the retrograde axonal transport of neurotensin in dopaminergic neurones. European journal of pharmacology. vol 186. issue 1. 1991-03-15. PMID:1704309. |
we therefore conclude that the retrograde axonal transport of neurotensin in the nigrostriatal pathway is not affected by reduced dopaminergic firing or by inhibition of the striatal release of dopamine. |
1991-03-15 |
2023-08-11 |
rat |
| K P Gudehithlu, A M Duchemin, G A Tejwani, N H Neff, M Hadjiconstantino. Preproenkephalin mRNA and methionine-enkephalin increase in mouse striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment. Journal of neurochemistry. vol 56. issue 3. 1991-03-15. PMID:1899692. |
pretreatment with the monoamine oxidase b inhibitor deprenyl or the dopamine transport blocker nomifensine prevented these changes, suggesting that the changes were related to the partial loss of dopaminergic neurons rather than to mptp. |
1991-03-15 |
2023-08-11 |
mouse |
| W Kolbinger, K Kohler, H Oetting, R Weile. Endogenous dopamine and cyclic events in the fish retina, I: HPLC assay of total content, release, and metabolic turnover during different light/dark cycles. Visual neuroscience. vol 5. issue 2. 1991-03-13. PMID:2278941. |
dopaminergic activity was measured during different light/dark cycles, during continuous darkness, and during short-term light and dark adaptation within 1 h. during a 12-h light/12-h dark cycle, the total content of endogenous dopamine was high during the dark phase and low during the light phase. |
1991-03-13 |
2023-08-11 |
Not clear |
| W Kolbinger, K Kohler, H Oetting, R Weile. Endogenous dopamine and cyclic events in the fish retina, I: HPLC assay of total content, release, and metabolic turnover during different light/dark cycles. Visual neuroscience. vol 5. issue 2. 1991-03-13. PMID:2278941. |
the concentration of the dopamine breakdown product 3,4-dihydroxyphenylacetic acid (dopac), which reflects the endogenous dopaminergic activity, was high during the light phase and low during the dark phase. |
1991-03-13 |
2023-08-11 |
Not clear |
| J Luthman, E Brodin, E Sundström, B Wiehage. Studies on brain monoamine and neuropeptide systems after neonatal intracerebroventricular 6-hydroxydopamine treatment. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 5. 1991-03-08. PMID:1704172. |
in order to study the effects of a neonatal dopamine lesion on dopaminergic, serotonergic and peptidergic systems, sprague-dawley rats were treated by intracerebroventricular administration of 6-hydroxydopamine (100 micrograms, days 3 and 6) following desipramine pretreatment (25 mg/kg s.c.). |
1991-03-08 |
2023-08-11 |
rat |