| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming Li, Xue-Ke Yang, Jian Yang, Tong-Xia Li, Chi Cui, Xiang Peng, Jie Lei, Kun Ren, Jie Ming, Pei Zhang, Bo Tia. Ketamine ameliorates post-traumatic social avoidance by erasing the traumatic memory encoded in VTA-innervated BLA engram cells. Neuron. 2024-07-20. PMID:39032491. |
furthermore, activation or inhibition of dopaminergic projections from the ventral tegmental area to the bla effectively mimics or blocks the therapeutic effect of re-exposure with ketamine and is dopamine d2 receptor dependent. |
2024-07-20 |
2024-07-24 |
mouse |
| Cintia Klaudia Finszter, Róbert Kemecsei, Gergely Zachar, Ágota Ádám, András Csilla. Gestational VPA exposure reduces the density of juxtapositions between TH+ axons and calretinin or calbindin expressing cells in the ventrobasal forebrain of neonatal mice. Frontiers in neuroanatomy. vol 18. 2024-07-19. PMID:39026519. |
previous quantitative morphometric studies from our laboratory showed a marked reduction and defasciculation of the mesotelencephalic dopaminergic pathway of vpa treated mice, along with a decrease in tissue dopamine in the nucleus accumbens (nac), but not in the caudatoputamen (cpu). |
2024-07-19 |
2024-07-21 |
mouse |
| Katarzyna Czarzasta, Dorota Sztechman, Tymoteusz Zera, Malgorzata Wojciechowska, Agnieszka Segiet-Swiecicka, Liana Puchalska, Karol Momot, Ilona Joniec-Maciejak, Ewa Machaj, Elizabeth M Sajdel-Sulkowsk. Age- and sex-dependent cardiovascular impact of maternal perinatal stress and altered dopaminergic metabolism in the medulla oblongata of the offspring. American journal of physiology. Heart and circulatory physiology. 2024-07-19. PMID:39028279. |
a significant decrease in homovanillic acid, a dopamine metabolite and indicator of dopaminergic activity, was observed in adult stress-exposed female offspring. |
2024-07-19 |
2024-07-21 |
rat |
| Katarina Tomović Pavlović, Budimir S Ilić, Luisa Leitzbach, Kameliya K Anichina, Denitsa Yancheva, Aleksandra Živković, Anelia Ts Mavrova, Holger Stark, Andrija Smelcerovi. Bis(benzimidazol-2-yl)amine-based DPP-4 Inhibitors Potentially Suitable for Combating Diabetes and Associated Nervous System Alterations. Chemistry & biodiversity. 2024-07-13. PMID:39001610. |
the potential beneficial effects on dopamine synthesis and the survival of dopaminergic neurons could be mediated by dpp-4 inhibition. |
2024-07-13 |
2024-07-15 |
human |
| Ian Cone, Claudia Clopath, Harel Z Shouva. Learning to express reward prediction error-like dopaminergic activity requires plastic representations of time. Nature communications. vol 15. issue 1. 2024-07-12. PMID:38997276. |
the td algorithm has been traditionally mapped onto the dopaminergic system, as firing properties of dopamine neurons can resemble rpes. |
2024-07-12 |
2024-07-15 |
Not clear |
| Vrinda Jain, Phillip J M Liang, Sushmitha Raja, Meena Mikhael, Morven A Camero. Light activation of the dopaminergic system occurs after eye-opening in the mouse retina. Frontiers in ophthalmology. vol 3. 2024-07-10. PMID:38983102. |
dopaminergic amacrine cells in the adult retina release dopamine in response to light stimulation, however, the light-induced activity of these cells in during postnatal development is not known. |
2024-07-10 |
2024-07-12 |
mouse |
| Vrinda Jain, Phillip J M Liang, Sushmitha Raja, Meena Mikhael, Morven A Camero. Light activation of the dopaminergic system occurs after eye-opening in the mouse retina. Frontiers in ophthalmology. vol 3. 2024-07-10. PMID:38983102. |
our data suggests that dopaminergic cell activation and light-induced dopamine release in the retina is primarily driven by classical photoreceptors after eye-opening. |
2024-07-10 |
2024-07-12 |
mouse |
| Miguel Ribeiro, Jonas Campos, Tiffany S Pinho, Belém Sampaio-Marques, Sandra Barata-Antunes, Jorge Ribeiro Cibrão, Ricardo Araújo, Sara Duarte-Silva, Elsa Moreira, Rui A Sousa, Pedro M Costa, António J Salgad. Human platelet lysate supports SH-SY5Y neuroblastoma cell proliferation and differentiation into a dopaminergic-like neuronal phenotype under xenogeneic-free culture conditions. Biotechnology journal. vol 19. issue 7. 2024-07-10. PMID:38987218. |
furthermore, following treatment with retinoic acid (ra) and further stimulation with brain-derived neurotrophic factor (bdnf) and nerve growth factor beta (ngf-β), the percentage of sh-sy5y cells stained positive for dopaminergic neuronal differentiation markers (tyrosine hydroxylase [th] and dopamine transporter [dat]) was higher in hpl or fd-hpl than in fbs, and gene expression of dopaminergic markers th, dat, and dr2 was also detected. |
2024-07-10 |
2024-07-13 |
human |
| Sophia J Weber, Alex B Kawa, Alana L Moutier, Madelyn M Beutler, Lara M Koyshman, Cloe D Moreno, Jonathan G Westlake, Amanda M Wunsch, Marina E Wol. Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression of incubation of cocaine craving. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979157. |
however, despite the importance of dopaminergic signaling in the nacc for motivated behavior, little is known about the role that dopamine (da) plays in the incubation of cocaine craving. |
2024-07-09 |
2024-07-12 |
rat |
| Dev Desai, Jekee Patel, Falak Saiyed, Himarshi Upadhyay, Prashant Kariya, Jitendra Pate. A Literature Review on Holistic Well-Being and Dopamine Fasting: An Integrated Approach. Cureus. vol 16. issue 6. 2024-07-06. PMID:38966464. |
popularly known as dopaminergic detox or dopamine fasting, it is a concept that aims at reducing dependence on instant satisfaction gratification and overstimulation to attain mental clarity, lessen anxiety, and be able to enjoy everyday events again. |
2024-07-06 |
2024-07-08 |
Not clear |
| Muhammad Abdullah, Shih-Hsien Lin, Li-Chung Huang, Nan-Tsing Chiu, Yen Kuang Yan. Fat loss and muscle gain: The possible role of striatal dopaminergic tone in determining the efficacy of physical exercise. Journal of the Formosan Medical Association = Taiwan yi zhi. 2024-07-04. PMID:38965009. |
striatal dopaminergic tone was assessed by measuring dopamine transporter availability using technetium-99 m labelled tropane derivative, [99mtc]trodat-1 (trodat), single-photon emission computed tomography, and body composition (fat and muscles mass) was analysed using bioelectrical impedance. |
2024-07-04 |
2024-07-11 |
Not clear |
| Charltien Long, Kwang Lee, Long Yang, Theresia Dafalias, Alexander K Wu, Sotiris C Masmanidi. Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling. Nature neuroscience. 2024-07-03. PMID:38961230. |
it is thought that dopaminergic neurons drive certain behaviors by rapidly modulating striatal spiking activity; however, a view has emerged that only artificially high (that is, supra-physiological) dopamine signals alter behavior on fast timescales. |
2024-07-03 |
2024-07-10 |
mouse |
| Joohyun An, Minkyu Shin, Geunyoung Beak, Jinho Yoon, Seewoo Kim, Hyeon-Yeol Cho, Jeong-Woo Cho. Drug Evaluation of Parkinson's Disease Patient-Derived Midbrain Organoids Using Mesoporous Au Nanodot-Patterned 3D Concave Electrode. ACS sensors. 2024-07-02. PMID:38954790. |
after the treatment of pd midbrain organoids with levodopa, the drug for pd, the increase in dopamine level was detected due to the activation of dopaminergic neurons by the drug. |
2024-07-02 |
2024-07-06 |
human |
| Reem M Gahtani, Shoaib Shoaib, Umme Hani, R Jayachithra, Mohammad N Alomary, Waseem Chauhan, Roshan Jahan, Saba Tufail, Mohammad Azam Ansar. Combating Parkinson's Disease with Plant-Derived Polyphenols: Targeting Oxidative Stress and Neuroinflammation. Neurochemistry international. 2024-07-01. PMID:38950626. |
dopamine metabolism, mitochondrial dysfunction, and neuroinflammation in dopaminergic neurons have been implicated in the pathogenesis of parkinson's disease. |
2024-07-01 |
2024-07-04 |
Not clear |
| Chloé Halfhide, Tommie L Cammarano, Kevin A Anderson, Stefani M Galik, Julien Rossignol, Gary L Dunbar, Michael I Sandstro. Using Microdialysis to Monitor Dopaminergic Support of Limb-Use Control Following Mesencephalic Neurosphere Transplantation in a Rodent Model of Parkinson's Disease. Behavioural brain research. 2024-06-30. PMID:38945302. |
our laboratory previously demonstrated that transplanted dopaminergic cells can elicit skilled movement recovery known to depend on phasic dopamine release. |
2024-06-30 |
2024-07-03 |
human |
| Md Reyaz Alam, Vaishali Dobhal, Shamsher Sing. Neuroprotective potential of solanesol against tramadol induced zebrafish model of Parkinson's disease: insights from neurobehavioral, molecular, and neurochemical evidence. Drug and chemical toxicology. 2024-06-28. PMID:38938099. |
parkinson's disease (pd) is a prevalent neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) and subsequent depletion of dopamine in the striatum. |
2024-06-28 |
2024-06-30 |
human |
| Sandeep Sathyanandan Nair, Srinivasa Chakravarth. A Computational Model of Deep Brain Stimulation for Parkinson's Disease Tremor and Bradykinesia. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928620. |
the most common approach in managing the symptoms is replenishing the lost dopamine in the form of taking dopaminergic medications such as levodopa, despite its long-term complications. |
2024-06-27 |
2024-06-29 |
Not clear |
| Andrew Lian. Assessing gait dysfunction severity in Parkinson's Disease using 2-Stream Spatial-Temporal Neural Network. Journal of biomedical informatics. 2024-06-26. PMID:38925280. |
pd primarily impacts dopaminergic neurons in the brain's substantia nigra, resulting in dopamine deficiency and gait impairments such as bradykinesia and rigidity. |
2024-06-26 |
2024-06-29 |
Not clear |
| Stephanie M Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Oluwatofunmi Oteju, Marzieh Daniali, Joanna A Canagarajah, Teresa LuPone, Krisna Mompho, Kaitlyn Runner, Emily Nickoloff-Bybel, Benjamin Li, Meng Niu, Johannes C M Schlachetzki, Howard S Fox, Peter J Gaskil. Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915663. |
finally, using hiv as an example of a chronic inflammatory disease that is substantively worsened by comorbid substance use disorders (suds) that impact dopaminergic signaling, we show increased effects of dopamine on inflammasome activation and il-1β in the presence of hiv in both human macrophages and microglia. |
2024-06-25 |
2024-06-27 |
human |
| Vittorio Calabrese, Naomi Osakabe, Foziya Khan, Uwe Wenzel, Sergio Modafferi, Lidia Nicolosi, Tilman Fritsch, Ursula M Jacob, Ali S Abdelhameed, Luay Rasha. Frankincense: A neuronutrient to approach Parkinson's disease treatment. Open medicine (Warsaw, Poland). vol 19. issue 1. 2024-06-24. PMID:38911256. |
parkinson's disease (pd), characterized by tremor, slowness of movement, stiffness, and poor balance, is due to a significant loss of dopaminergic neurons in the substantia nigra pars compacta and dopaminergic nerve terminals in the striatum with deficit of dopamine. |
2024-06-24 |
2024-06-26 |
Not clear |