| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Zhuo, Wen-Shui Li, Wen Lu, Xuan Li, Li-Te Ge, Yan Huang, Qing-Tao Gao, Yu-Jia Deng, Xin-Chen Jiang, Zi-Wei Lan, Que Deng, Yong-Heng Chen, Yi Xiao, Shuo Lu, Feng Jiang, Zuo Liu, Li Hu, Yu Liu, Yu Ding, Zheng-Wen He, De-An Tan, Da Duan, Ming L. TGF-β1 mediates hypoxia-preconditioned olfactory mucosa mesenchymal stem cells improved neural functional recovery in Parkinson's disease models and patients. Military Medical Research. vol 11. issue 1. 2024-07-21. PMID:39034405. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the substantia nigra (sn). |
2024-07-21 |
2024-07-24 |
Not clear |
| Anjali Rani, Mohd Aslam, Javed Khan, Garima Pandey, Prashant Singh, R S Maharia, Bhaskara Nan. Computational Insights into Chromene/pyran Derivatives: Molecular Docking, ADMET Studies, DFT Calculations, and MD Simulations as Promising Candidates for Parkinson's Disease. Chemistry & biodiversity. 2024-07-09. PMID:38818615. |
although pd is commonly associated with a decline of dopaminergic neurons in the substantia nigra, other diagnostic criteria and biomarkers also exist. |
2024-07-09 |
2024-07-12 |
Not clear |
| Wessam H Elesawy, Ayman E El-Sahar, Rabab H Sayed, Ahmed M Ashour, Shuruq E Alsufyani, Hany H Arab, Esraa A Kandi. Repurposing ezetimibe as a neuroprotective agent in a rotenone-induced Parkinson's disease model in rats: Role of AMPK/SIRT-1/PGC-1α signaling and autophagy. International immunopharmacology. vol 138. 2024-07-09. PMID:38981225. |
as a severe neurological disorder, parkinson's disease (pd) is distinguished by dopaminergic neuronal degeneration in the substantia nigra (sn), culminating in motor impairments. |
2024-07-09 |
2024-07-12 |
rat |
| Reem M Gahtani, Shoaib Shoaib, Umme Hani, R Jayachithra, Mohammad N Alomary, Waseem Chauhan, Roshan Jahan, Saba Tufail, Mohammad Azam Ansar. Combating Parkinson's Disease with Plant-Derived Polyphenols: Targeting Oxidative Stress and Neuroinflammation. Neurochemistry international. 2024-07-01. PMID:38950626. |
parkinson's disease (pd) is a devastating neurodegenerative disorder predominantly affecting the elderly, characterized by the loss of dopaminergic neurons in the substantia nigra. |
2024-07-01 |
2024-07-04 |
Not clear |
| Mengjie Fu, Qiuchen Wang, Lihui Gao, Xin Yuan, Ju Wan. Antimicrobial drugs for Parkinson's disease: existing therapeutic strategies and novel drugs exploration. Ageing research reviews. 2024-06-28. PMID:38942200. |
parkinson's disease (pd), the second most common neurodegenerative disorder, is characterized by loss of dopaminergic neurons in the substantia nigra, as well as the abnormal accumulation of misfolded α-synuclein. |
2024-06-28 |
2024-07-01 |
Not clear |
| Damien Meng-Kiat Leow, Irwin Kee-Mun Cheah, Lucrecia Chen, Yang-Kai Ng, Crystal Jing-Jing Yeo, Barry Halliwell, Wei-Yi On. Ergothioneine-Mediated Neuroprotection of Human iPSC-Derived Dopaminergic Neurons. Antioxidants (Basel, Switzerland). vol 13. issue 6. 2024-06-27. PMID:38929132. |
cell death involving oxidative stress and mitochondrial dysfunction is a major cause of dopaminergic neuronal loss in the substantia nigra (sn) of parkinson's disease patients. |
2024-06-27 |
2024-06-29 |
human |
| Hayato Itoh, Masahiro Oda, Shinji Saiki, Koji Kamagata, Wataru Sako, Kei-Ichi Ishikawa, Nobutaka Hattori, Shigeki Aoki, Kensaku Mor. Preliminary study of substantia nigra analysis by tensorial feature extraction. International journal of computer assisted radiology and surgery. 2024-06-27. PMID:38935246. |
since one of the characteristics of pd is the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, we propose a feature extraction method for analysing the differences in the substantia nigra between pd and non-pd patients. |
2024-06-27 |
2024-06-29 |
Not clear |
| Andrew Lian. Assessing gait dysfunction severity in Parkinson's Disease using 2-Stream Spatial-Temporal Neural Network. Journal of biomedical informatics. 2024-06-26. PMID:38925280. |
pd primarily impacts dopaminergic neurons in the brain's substantia nigra, resulting in dopamine deficiency and gait impairments such as bradykinesia and rigidity. |
2024-06-26 |
2024-06-29 |
Not clear |
| Alejandro Soto-Avellaneda, Alexandra E Oxford, Fabio Halla, Peyton Vasquez, Emily Oe, Anton D Pugel, Alyssa M Schoenfeld, Matthew C Tillman, André Cuevas, Eric A Ortlund, Brad E Morriso. FABP5-binding lipids regulate autophagy in differentiated SH-SY5Y cells. PloS one. vol 19. issue 6. 2024-06-20. PMID:38900831. |
the motor features of parkinson's disease result from loss of dopaminergic neurons in the substantia nigra with autophagy dysfunction being closely linked to this disease. |
2024-06-20 |
2024-06-23 |
Not clear |
| Alejandro Soto-Avellaneda, Alexandra E Oxford, Fabio Halla, Peyton Vasquez, Emily Oe, Anton D Pugel, Alyssa M Schoenfeld, Matthew C Tillman, André Cuevas, Eric A Ortlund, Brad E Morriso. FABP5-binding lipids regulate autophagy in differentiated SH-SY5Y cells. PloS one. vol 19. issue 6. 2024-06-20. PMID:38900831. |
we focused specifically upon fabp5 due to its heightened expression in dopaminergic neurons within the substantia nigra and sh-sy5y cells. |
2024-06-20 |
2024-06-23 |
Not clear |
| Maya Belghazi, Cécile Iborra, Ophélie Toutendji, Manon Lasserre, Dominique Debanne, Jean-Marc Goaillard, Béatrice Marquèze-Poue. High-Resolution Proteomics Unravel a Native Functional Complex of Cav1.3, SK3, and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels in Midbrain Dopaminergic Neurons. Cells. vol 13. issue 11. 2024-06-19. PMID:38891076. |
in order to demonstrate the presence of these molecular interactions in situ, we used proximity ligation assay (pla) imaging on midbrain slices containing the substantia nigra, and we could ascertain the presence of these protein complexes specifically in substantia nigra dopaminergic neurons. |
2024-06-19 |
2024-06-21 |
Not clear |
| Benedetta Gambosi, Francesco Jamal Sheiban, Marco Biasizzo, Alberto Antonietti, Egidio D'angelo, Alberto Mazzoni, Alessandra Pedrocch. A Model with Dopamine Depletion in Basal Ganglia and Cerebellum Predicts Changes in Thalamocortical Beta Oscillations. International journal of neural systems. 2024-06-17. PMID:38886870. |
the discovery that those motor symptoms result from the death of dopaminergic cells in the substantia nigra led to focus most of parkinsonism research on the basal ganglia (bg). |
2024-06-17 |
2024-06-21 |
Not clear |
| Caleb A H Jones, Benjamin P Brown, Daniel C Schultz, Julie Engers, Valerie M Kramlinger, Jens Meiler, Craig W Lindsle. Computer-Aided Design and Biological Evaluation of Diazaspirocyclic D ACS chemical neuroscience. 2024-06-08. PMID:38847395. |
computer-aided design and biological evaluation of diazaspirocyclic d parkinson's disease (pd) is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra, resulting in motor dysfunction. |
2024-06-08 |
2024-06-10 |
Not clear |
| Yichen Zhao, Weiwei Shen, Minjie Zhang, Min Guo, Yunxiao Dou, Sida Han, Jintai Yu, Mei Cui, Yanxin Zha. DDAH-1 maintains endoplasmic reticulum-mitochondria contacts and protects dopaminergic neurons in Parkinson's disease. Cell death & disease. vol 15. issue 6. 2024-06-07. PMID:38849335. |
the loss of dopaminergic neurons in the substantia nigra is a hallmark of pathology in parkinson's disease (pd). |
2024-06-07 |
2024-06-10 |
rat |
| Ozge Akyazı, Dılara Korkmaz, Sule Coskun Cevhe. Experimental Parkinson Models and Green Chemistry Approach. Behavioural brain research. 2024-06-06. PMID:38844056. |
the disease primarily impairs the functional capacity of the person with cardinal findings such as tremor, bradykinesia, etc., as a result of the loss of dopaminergic neurons in the substantia nigra. |
2024-06-06 |
2024-06-10 |
Not clear |
| Penelope A Young, Olivia Waller, Katherine Ball, Chad C Williams, Raad Nashm. Phasic stimulation of dopaminergic neurons of the lateral substantia nigra increases open field exploratory behaviour and reduces habituation over time. Neuroscience. 2024-06-05. PMID:38838978. |
phasic stimulation of dopaminergic neurons of the lateral substantia nigra increases open field exploratory behaviour and reduces habituation over time. |
2024-06-05 |
2024-06-08 |
mouse |
| Riptee Thakur, Chandana Nagaraj, Raman Kumar Joshi, Jitender Saini, Ravi Yadav, Pardeep Kuma. Standardization and Clinical Use of a Single-vial Formulation of Technetium-99m-Trodat Using Autoclave Method. Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India. vol 39. issue 1. 2024-06-01. PMID:38817725. |
parkinson's disease (pd) is characterized by the degeneration of dopaminergic neurons in the substantia nigra. |
2024-06-01 |
2024-06-02 |
Not clear |
| Mohammad Sophiabadi, Nafiseh Rastgoo, Hashem Haghdoost-Yazd. Retraction Note: Dopaminergic Neuronal Death in Substantia Nigra Associates with Serum Levels of Total Bilirubin, Selenium, and Zinc: Evidences from 6-Hydroxydopamine Animal Model of Parkinson's Disease. Biological trace element research. 2024-05-29. PMID:38809398. |
retraction note: dopaminergic neuronal death in substantia nigra associates with serum levels of total bilirubin, selenium, and zinc: evidences from 6-hydroxydopamine animal model of parkinson's disease. |
2024-05-29 |
2024-06-03 |
Not clear |
| Brian H Kopell, Deepak A Kaji, Lora E Liharska, Eric Vornholt, Alissa Valentine, Anina Lund, Alice Hashemi, Ryan C Thompson, Terry Lohrenz, Jessica S Johnson, Nicole Bussola, Esther Cheng, You Jeong Park, Punit Shah, Weiping Ma, Richard Searfoss, Salman Qasim, Gregory M Miller, Nischal Mahaveer Chand, Alisha Aristel, Jack Humphrey, Lillian Wilkins, Kimia Ziafat, Hannah Silk, Lisa M Linares, Brendan Sullivan, Claudia Feng, Seth R Batten, Dan Bang, Leonardo S Barbosa, Thomas Twomey, Jason P White, Marina Vannucci, Beniamino Hadj-Amar, Vanessa Cohen, Prashant Kota, Emily Moya, Marysia-Kolbe Rieder, Martijn Figee, Girish N Nadkarni, Michael S Breen, Kenneth T Kishida, Joseph Scarpa, Douglas M Ruderfer, Niven R Narain, Pei Wang, Michael A Kiebish, Eric E Schadt, Ignacio Saez, P Read Montague, Noam D Beckmann, Alexander W Charne. Multiomic foundations of human prefrontal cortex tissue function. medRxiv : the preprint server for health sciences. 2024-05-27. PMID:38798344. |
rna transcript expression within multiple pfc cell types was associated with fluctuations of dopaminergic, serotonergic, and/or noradrenergic neurotransmission in the substantia nigra measured while participants played a computer game that engaged higher-order brain functions. |
2024-05-27 |
2024-05-31 |
human |
| Gayatri Reddy Aaluri, Yashmit Choudhary, Subodh Kuma. Mitochondria-Associated MicroRNAs and Parkinson's Disease. Neuroscience insights. vol 19. 2024-05-27. PMID:38800624. |
parkinson's disease (pd) occurs as a result of the progressive loss of dopaminergic neurons within the substantia nigra causing motor and non-motor symptoms and has become more prevalent within the last several decades. |
2024-05-27 |
2024-05-31 |
Not clear |