| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B A Blanchard, S Steindorf, S Wang, R LeFevre, R F Mankes, S D Glic. Prenatal ethanol exposure alters ethanol-induced dopamine release in nucleus accumbens and striatum in male and female rats. Alcoholism, clinical and experimental research. vol 17. issue 5. 1994-02-08. PMID:8279684. |
using in vivo microdialysis, ethanol-induced dopamine release in nucleus accumbens and striatum was examined in adult male and female long-evans rats exposed prenatally to ethanol and in controls. |
1994-02-08 |
2023-08-12 |
rat |
| B A Blanchard, S Steindorf, S Wang, R LeFevre, R F Mankes, S D Glic. Prenatal ethanol exposure alters ethanol-induced dopamine release in nucleus accumbens and striatum in male and female rats. Alcoholism, clinical and experimental research. vol 17. issue 5. 1994-02-08. PMID:8279684. |
control rats showed increased dopamine release in nucleus accumbens and striatum in response to 0.5 g/kg ethanol, but not to 1.0 g/kg. |
1994-02-08 |
2023-08-12 |
rat |
| B A Blanchard, S Steindorf, S Wang, R LeFevre, R F Mankes, S D Glic. Prenatal ethanol exposure alters ethanol-induced dopamine release in nucleus accumbens and striatum in male and female rats. Alcoholism, clinical and experimental research. vol 17. issue 5. 1994-02-08. PMID:8279684. |
data are discussed in terms of sex-specific shifts in the dose-response function for ethanol-induced dopamine release resulting from prenatal ethanol exposure. |
1994-02-08 |
2023-08-12 |
rat |
| Y L Wang, J W Wei, A Y Su. Effects of ethanol on brain monoamine content of spontaneously hypertensive rats (SHR). Neurochemical research. vol 18. issue 12. 1994-01-28. PMID:7505892. |
spontaneously hypertensive rats (shr) were administered either 2.4 g/kg ethanol or an isocaloric glucose daily for 4 weeks and the levels of norepinephrine (ne), epinephrine (ep), dopamine (da), serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in different brain regions were determined. |
1994-01-28 |
2023-08-12 |
rat |
| C Heidbreder, P De Witt. Ethanol differentially affects extracellular monoamines and GABA in the nucleus accumbens. Pharmacology, biochemistry, and behavior. vol 46. issue 2. 1994-01-27. PMID:8265704. |
the magnitude, direction, and time course of the effects of acute administration of ethanol (0.1 or 1.0 g/kg) on the extracellular levels of dopamine (da), dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 5-hydroxytryptamine (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), and gaba within the nucleus accumbens of the rat were analysed using microdialysis in conjunction with high-pressure liquid chromatography and electrochemical detection. |
1994-01-27 |
2023-08-12 |
rat |
| R Y Shen, L A Chiod. Acute withdrawal after repeated ethanol treatment reduces the number of spontaneously active dopaminergic neurons in the ventral tegmental area. Brain research. vol 622. issue 1-2. 1994-01-06. PMID:8242369. |
the effect of acute withdrawal, after repeated ethanol administration, on the electrophysiological activity of dopamine (da) neurons in the ventral tegmental area was studied. |
1994-01-06 |
2023-08-12 |
rat |
| S Rassnick, L Stinus, G F Koo. The effects of 6-hydroxydopamine lesions of the nucleus accumbens and the mesolimbic dopamine system on oral self-administration of ethanol in the rat. Brain research. vol 623. issue 1. 1993-12-21. PMID:8221085. |
previous studies using this self-administration model have shown that dopamine receptor antagonists injected systemically or directly into the terminal regions of the mesolimbic dopamine system decrease lever pressing for ethanol, suggesting an important role for dopamine in ethanol reinforcement. |
1993-12-21 |
2023-08-12 |
rat |
| S Rassnick, L Stinus, G F Koo. The effects of 6-hydroxydopamine lesions of the nucleus accumbens and the mesolimbic dopamine system on oral self-administration of ethanol in the rat. Brain research. vol 623. issue 1. 1993-12-21. PMID:8221085. |
results of this study show that 6-hydroxydopamine (6-ohda)-induced lesions of the mesolimbic dopamine system, sufficient to produce a 93% depletion of dopamine in the nucleus accumbens, an 85% depletion in the olfactory tubercle, an 82% depletion in the frontal cortex and a 78% depletion in the amygdala, failed to alter ethanol self-administration as measured by the total lever presses. |
1993-12-21 |
2023-08-12 |
rat |
| D Benjamin, E R Grant, L A Pohoreck. Naltrexone reverses ethanol-induced dopamine release in the nucleus accumbens in awake, freely moving rats. Brain research. vol 621. issue 1. 1993-12-09. PMID:7693299. |
locally applied ethanol (5% infused transprobe) resulted in substantial increases in dopamine in dialysate. |
1993-12-09 |
2023-08-12 |
rat |
| D Benjamin, E R Grant, L A Pohoreck. Naltrexone reverses ethanol-induced dopamine release in the nucleus accumbens in awake, freely moving rats. Brain research. vol 621. issue 1. 1993-12-09. PMID:7693299. |
during ethanol administration dose-dependently reversed ethanol-induced increases in extracellular dopamine and its metabolite homovanillic acid but not serotonin. |
1993-12-09 |
2023-08-12 |
rat |
| D Benjamin, E R Grant, L A Pohoreck. Naltrexone reverses ethanol-induced dopamine release in the nucleus accumbens in awake, freely moving rats. Brain research. vol 621. issue 1. 1993-12-09. PMID:7693299. |
these data demonstrate an essential role for the endogenous opioid system in stimulation of dopamine release by ethanol in a brain area associated with reward and support the opioid system as a prime target for pharmacological modulation of the rewarding effects and consumption of ethanol. |
1993-12-09 |
2023-08-12 |
rat |
| F Weiss, M T Lorang, F E Bloom, G F Koo. Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. The Journal of pharmacology and experimental therapeutics. vol 267. issue 1. 1993-11-29. PMID:8229752. |
this hypothesis was tested by measuring dopamine (da) release by intracranial microdialysis during voluntary oral ethanol self-administration in alcohol-preferring (p) and genetically heterogeneous wistar rats. |
1993-11-29 |
2023-08-12 |
rat |
| G I Kovalev, E A Budygin, R R Gaĭnetdinov, V S Kudrin, S S Trofimov, R U Ostrovskai. [The sodium oxybutyrate and nooglutil correction of dopamine release in the striatum of prenatally alcoholized rat pups]. Biulleten' eksperimental'noi biologii i meditsiny. vol 116. issue 7. 1993-10-28. PMID:8400184. |
the influence of prenatal exposure to ethanol on endogenous dopamine (da) release from perfused isolated striata of 20-day-old rats was studied, as well as its correction by nootropic drugs: sodium hydroxy butyrate and nooglutil. |
1993-10-28 |
2023-08-12 |
rat |
| J J Woodward, L Brown, R A Gonzale. Modulation of ethanol-induced inhibition of N-methyl-D-aspartate-stimulated neurotransmitter release by glycine. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 1. 1993-10-07. PMID:1845534. |
similarly, ethanol (25-200 mm) markedly inhibited the nmda stimulated release of tritiated and endogenous dopamine without affecting basal release. |
1993-10-07 |
2023-08-11 |
rat |
| F Fadda, G Colombo, G L Gess. Genetic sensitivity to effect of ethanol on dopaminergic system in alcohol preferring rats. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 1. 1993-10-07. PMID:1845574. |
the effect of ethanol (etoh) on dopamine (da) metabolism in the caudate nucleus (cn), olfactory tubercle (ot) and medial prefrontal cortex (mpfc) was compared in 2 selectively bred lines of rats, one etoh-preferring (sp) and the other -non preferring (snp). |
1993-10-07 |
2023-08-11 |
rat |
| M Diana, M Pistis, S Carboni, G L Gessa, Z L Rossett. Profound decrement of mesolimbic dopaminergic neuronal activity during ethanol withdrawal syndrome in rats: electrophysiological and biochemical evidence. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 17. 1993-10-05. PMID:8367449. |
consistently, dopamine outflow in the nucleus accumbens and its acid metabolites were reduced after abruptly stopping chronic ethanol administration. |
1993-10-05 |
2023-08-12 |
rat |
| O M Laudanno, J A Cesolari, O A Bedini, P San Migue. [Role of ACE in the gastric cytoprotection. Dopaminergic and peripheral alpha 2 adrenergic mechanisms]. Acta gastroenterologica Latinoamericana. vol 22. issue 2. 1993-05-25. PMID:1338678. |
subsequently, drugs with known role in gastric mucosa cytoprotection, such as enprostil, paracetamol, ketotiphen, levamisole, diazepam, bromocriptine, dopamine and clonidine, before and after absolute ethanol gastric injury were also studied. |
1993-05-25 |
2023-08-11 |
rat |
| Z L Rossetti, Y Hmaidan, M Diana, G L Gess. Lack of tolerance to ethanol-induced dopamine release in the rat ventral striatum. European journal of pharmacology. vol 231. issue 2. 1993-04-20. PMID:8453975. |
the effect of ethanol challenge on the extracellular concentrations of dopamine, 3,4-dihydroxy-phenylacetic acid and homovanillic acid was studied in the ventral striatum of rats repeatedly treated with ethanol. |
1993-04-20 |
2023-08-12 |
rat |
| Z L Rossetti, Y Hmaidan, M Diana, G L Gess. Lack of tolerance to ethanol-induced dopamine release in the rat ventral striatum. European journal of pharmacology. vol 231. issue 2. 1993-04-20. PMID:8453975. |
however, in ethanol-treated animals the increased output of dopamine and metabolites after ethanol challenge (1 or 2 g/kg i.p.) |
1993-04-20 |
2023-08-12 |
rat |
| Z L Rossetti, Y Hmaidan, M Diana, G L Gess. Lack of tolerance to ethanol-induced dopamine release in the rat ventral striatum. European journal of pharmacology. vol 231. issue 2. 1993-04-20. PMID:8453975. |
these results indicate that tolerance does not develop to the ethanol-induced stimulation of dopamine release and support the hypothesis that activation of the mesolimbic dopamine system contributes to the reinforcing properties of ethanol. |
1993-04-20 |
2023-08-12 |
rat |