| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joanna Peris, Madeline R Steck, Eric G Kraus. Oxytocin treatment for alcoholism: Potential neurocircuitry targets. Neuropharmacology. vol 171. 2021-06-25. PMID:32304701. |
moreover, oxtr are expressed by non-dopaminergic neurons in the vta, such as gaba and glutamate neurons, which can both modulate the activity of dopamine vta neurons locally (in opposite directions) or can project to other brain regions, including the nac, where it can alter either positive reinforcement or aversion caused by ethanol. |
2021-06-25 |
2023-08-13 |
Not clear |
| Giulia Scuppa, Stefano Tambalo, Simone Pfarr, Wolfgang H Sommer, Angelo Bifon. Aberrant insular cortex connectivity in abstinent alcohol-dependent rats is reversed by dopamine D3 receptor blockade. Addiction biology. vol 25. issue 3. 2021-06-24. PMID:30907042. |
further, we evaluated the effects of sb-277011-a, a selective dopamine d3 receptor antagonist, known to decrease ethanol consumption. |
2021-06-24 |
2023-08-13 |
rat |
| Mia Ericson, Lisa Ulenius, Anna Andrén, Susanne Jonsson, Louise Adermark, Bo Söderpal. Different dopamine tone in ethanol high- and low-consuming Wistar rats. Addiction biology. vol 25. issue 3. 2021-06-24. PMID:31099157. |
different dopamine tone in ethanol high- and low-consuming wistar rats. |
2021-06-24 |
2023-08-13 |
rat |
| Mia Ericson, Lisa Ulenius, Anna Andrén, Susanne Jonsson, Louise Adermark, Bo Söderpal. Different dopamine tone in ethanol high- and low-consuming Wistar rats. Addiction biology. vol 25. issue 3. 2021-06-24. PMID:31099157. |
in vivo microdialysis was used to explore baseline levels as well as ethanol-induced increases of extracellular dopamine and taurine, in the nucleus accumbens (nac) of wistar rats voluntarily consuming large or small amounts of ethanol. |
2021-06-24 |
2023-08-13 |
rat |
| Mia Ericson, Lisa Ulenius, Anna Andrén, Susanne Jonsson, Louise Adermark, Bo Söderpal. Different dopamine tone in ethanol high- and low-consuming Wistar rats. Addiction biology. vol 25. issue 3. 2021-06-24. PMID:31099157. |
however, when categorized based on ethanol intake, rats consuming larger amounts of ethanol exhibited a lower dopamine tone in the nucleus accumbens and responded to ethanol with a slower elevation of extracellular taurine levels, as compared with low-consuming animals. |
2021-06-24 |
2023-08-13 |
rat |
| Loreto San Martin, Scarlet Gallegos, Anibal Araya, Nicol Romero, Giovanni Morelli, Joris Comhair, Robert J Harvey, Jean-Michel Rigo, Bert Brone, Luis G Aguay. Ethanol consumption and sedation are altered in mice lacking the glycine receptor α2 subunit. British journal of pharmacology. vol 177. issue 17. 2021-06-21. PMID:32436225. |
like other drugs of abuse, ethanol affects dopamine levels in the nucleus accumbens (nac), an important region of the mesolimbic system, causing a reinforcing effect. |
2021-06-21 |
2023-08-13 |
mouse |
| Zhong-Qin Wu, Ke Li, Xing Tian, Ming-Xi Zhou, Zong-Jun L. Schisandra chinensis water extract protects ethanol-induced neurotoxicity in Caenorhabditis elegans. Journal of food biochemistry. vol 44. issue 8. 2021-06-21. PMID:32524635. |
ethanol intake increased the tissue ethanol concentration, resulting in redox imbalance, and dopamine release and accumulation. |
2021-06-21 |
2023-08-13 |
caenorhabditis_elegans |
| Pratima Pandey, Anuradha Singh, Harjot Kaur, Anindya Ghosh-Roy, Kavita Bab. Increased dopaminergic neurotransmission results in ethanol dependent sedative behaviors in Caenorhabditis elegans. PLoS genetics. vol 17. issue 2. 2021-06-21. PMID:33524034. |
dopamine signaling plays an essential role in ethanol dependent behaviors in animals ranging from c. elegans to humans. |
2021-06-21 |
2023-08-13 |
caenorhabditis_elegans |
| Pratima Pandey, Anuradha Singh, Harjot Kaur, Anindya Ghosh-Roy, Kavita Bab. Increased dopaminergic neurotransmission results in ethanol dependent sedative behaviors in Caenorhabditis elegans. PLoS genetics. vol 17. issue 2. 2021-06-21. PMID:33524034. |
we devised an ethanol dependent assay in which mutants in the dopamine autoreceptor, dop-2, displayed a unique sedative locomotory behavior causing the animals to move in circles while dragging the posterior half of their body. |
2021-06-21 |
2023-08-13 |
caenorhabditis_elegans |
| Pratima Pandey, Anuradha Singh, Harjot Kaur, Anindya Ghosh-Roy, Kavita Bab. Increased dopaminergic neurotransmission results in ethanol dependent sedative behaviors in Caenorhabditis elegans. PLoS genetics. vol 17. issue 2. 2021-06-21. PMID:33524034. |
we further demonstrate that in dop-2 mutants, ethanol exposure increases dopamine secretion and functions in a dva interneuron dependent manner. |
2021-06-21 |
2023-08-13 |
caenorhabditis_elegans |
| Ella E Bauer, Allyse Shoeman, Trevor J Buhr, Karrie M Daniels, Mark Lyte, Peter J Clar. Voluntary binge-patterned alcohol drinking and sex-specific influences on monoamine-related neurochemical signatures in the mouse gut and brain. Alcoholism, clinical and experimental research. vol 45. issue 5. 2021-06-09. PMID:33704774. |
altered monoamine (i.e., serotonin, dopamine, and norepinephrine) activity following episodes of alcohol abuse plays key roles not only in the motivation to ingest ethanol, but also physiological dysfunction related to its misuse. |
2021-06-09 |
2023-08-13 |
mouse |
| Naimesh Solanki, Tomilowo Abijo, Carine Galvao, Philippe Darius, Kenneth Blum, Marjorie C Gondré-Lewi. Administration of a putative pro-dopamine regulator, a neuronutrient, mitigates alcohol intake in alcohol-preferring rats. Behavioural brain research. vol 385. 2021-05-17. PMID:32070691. |
it is postulated that increasing dopamine availability and thus restoring da homeostasis in the mesocorticolimbic system could reduce the motivation to seek and consume ethanol. |
2021-05-17 |
2023-08-13 |
rat |
| Paul J Fitzgeral. Neurodining: Common dietary factors may be substrates in novel biosynthetic pathways for monoaminergic neurotransmitters. Medical hypotheses. vol 138. 2021-05-14. PMID:32070787. |
another major aspect of the hypothesis is that phenol or polyphenol molecules, found in various plants, may combine with particular fats or even ethanol to form dopamine, which can then be converted to norepinephrine through the already established step involving the enzyme dopamine beta-hydroxylase. |
2021-05-14 |
2023-08-13 |
Not clear |
| Paul J Fitzgeral. Neurodining: Common dietary factors may be substrates in novel biosynthetic pathways for monoaminergic neurotransmitters. Medical hypotheses. vol 138. 2021-05-14. PMID:32070787. |
if such a biosynthetic pathway exists for converting ethanol to dopamine in humans, it could be a major factor in substance abuse, including early onset alcoholism. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yolanda Campos-Jurado, Jesús David Lorente, José Luis González-Romero, Luis Granero, Ana Polache, Lucía Hipólit. Impaired alcohol-induced dopamine release in the nucleus accumbens in an inflammatory pain model: behavioral implications in male rats. Pain. vol 161. issue 9. 2021-05-14. PMID:32379224. |
our microdialysis studies show that the presence of inflammatory pain blunted the increase of extracellular dopamine levels in the nucleus accumbens induced by 1.5 g/kg of ethanol (s.c.). |
2021-05-14 |
2023-08-13 |
rat |
| Wenxiao Du, Xiaoli Chen, Min Shi, Fuhua Bian, Zhenjun Zha. Ethanol affects behavior and HPA axis activity during development in zebrafish larvae. Scientific reports. vol 10. issue 1. 2021-03-24. PMID:33293624. |
ethanol exposure affects zebrafish behavior, increases the level of hpa axis hormones in zebrafish larvae, affects the level of neurotransmitters, and affects the expression of key genes in dopamine and serotonin metabolism. |
2021-03-24 |
2023-08-13 |
zebrafish |
| Eric A Engleman, Cynthia M Ingraham, Zachary A Rodd, James M Murphy, William J McBride, Zheng-Ming Din. The reinforcing effects of ethanol within the prelimbic cortex and ethanol drinking: Involvement of local dopamine D Drug and alcohol dependence. vol 214. 2021-03-16. PMID:32688071. |
the reinforcing effects of ethanol within the prelimbic cortex and ethanol drinking: involvement of local dopamine d previous studies have identified important mesolimbic regions in supporting the reinforcing effects of ethanol. |
2021-03-16 |
2023-08-13 |
Not clear |
| Caitlin R Coker, Bailey N Keller, Amy C Arnold, Yuval Silberma. Impact of High Fat Diet and Ethanol Consumption on Neurocircuitry Regulating Emotional Processing and Metabolic Function. Frontiers in behavioral neuroscience. vol 14. 2021-02-14. PMID:33574742. |
neuroinflammation in pivotal brain regions modulating metabolic function, food intake, and binge-like behaviors, such as the hypothalamus, mesolimbic dopamine circuits, and amygdala, may be a critical link between diet, ethanol, metabolic dysfunction, and neuropsychiatric conditions. |
2021-02-14 |
2023-08-13 |
Not clear |
| Nikita A Mitkin, Petr K Anokhin, Maria V Belopolskaya, Olga Y Frolova, Ekaterina A Kushnir, Maxim L Lovat, Vsevolod V Pavshintse. Active immunization against serum alcohol dehydrogenase normalizes brain dopamine metabolism disturbed during chronic alcohol consumption. Alcohol (Fayetteville, N.Y.). vol 83. 2021-01-08. PMID:31260795. |
additionally, we observed that inhibition of serum adh activity caused a decrease in peak dopamine levels during acute alcohol intake in chronically ethanol-fed rats during ethanol withdrawal that was associated with reduced tyrosine hydroxylase activity in the striatum. |
2021-01-08 |
2023-08-13 |
rat |
| Lisa Ulenius, Anna Andrén, Louise Adermark, Bo Söderpalm, Mia Ericso. Sub-chronic taurine administration induces behavioral sensitization but does not influence ethanol-induced dopamine release in the nucleus accumbens. Pharmacology, biochemistry, and behavior. vol 188. 2020-12-31. PMID:31770542. |
preclinical studies have shown that the amino acid taurine is of importance for the dopamine elevating properties of ethanol. |
2020-12-31 |
2023-08-13 |
Not clear |