Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Päivi Tuomainen, Anton Patsenka, Petri Hyytiä, Vladimir Grinevich, Kalervo Kiianma. Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. Alcohol (Fayetteville, N.Y.). vol 29. issue 2. 2003-07-11. PMID:12782253. |
extracellular levels of dopamine in the nucleus accumbens in aa and ana rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. |
2003-07-11 |
2023-08-12 |
rat |
Päivi Tuomainen, Anton Patsenka, Petri Hyytiä, Vladimir Grinevich, Kalervo Kiianma. Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. Alcohol (Fayetteville, N.Y.). vol 29. issue 2. 2003-07-11. PMID:12782253. |
ethanol is known to increase the release of dopamine in the nucleus accumbens. |
2003-07-11 |
2023-08-12 |
rat |
Päivi Tuomainen, Anton Patsenka, Petri Hyytiä, Vladimir Grinevich, Kalervo Kiianma. Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. Alcohol (Fayetteville, N.Y.). vol 29. issue 2. 2003-07-11. PMID:12782253. |
the question of whether this is a result of a direct or an indirect effect of ethanol on mesolimbic dopaminergic neurons was examined by investigating the extracellular levels of dopamine and its metabolites in the nucleus accumbens of alcohol-preferring aa (alko alcohol) and alcohol-avoiding ana (alko non-alcohol) rats after application of ethanol locally into either the nucleus accumbens or the ventral tegmental area with the use of reverse microdialysis. |
2003-07-11 |
2023-08-12 |
rat |
Päivi Tuomainen, Anton Patsenka, Petri Hyytiä, Vladimir Grinevich, Kalervo Kiianma. Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. Alcohol (Fayetteville, N.Y.). vol 29. issue 2. 2003-07-11. PMID:12782253. |
application of ethanol (200, 400, or 800 mm in dialysate) into the nucleus accumbens, but not into the ventral tegmental area, temporarily increased the accumbal levels of dopamine in a dose-dependent manner. |
2003-07-11 |
2023-08-12 |
rat |
Päivi Tuomainen, Anton Patsenka, Petri Hyytiä, Vladimir Grinevich, Kalervo Kiianma. Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. Alcohol (Fayetteville, N.Y.). vol 29. issue 2. 2003-07-11. PMID:12782253. |
because the concentrations of ethanol found to elevate the extracellular level of dopamine can hardly be considered pharmacologically relevant, the increase in accumbal dopamine levels after application of ethanol may be due to nonspecific membrane effects of ethanol. |
2003-07-11 |
2023-08-12 |
rat |
Päivi Tuomainen, Anton Patsenka, Petri Hyytiä, Vladimir Grinevich, Kalervo Kiianma. Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area. Alcohol (Fayetteville, N.Y.). vol 29. issue 2. 2003-07-11. PMID:12782253. |
the findings support the suggestion that the increase in the extracellular level of dopamine in the nucleus accumbens after systemic administration of ethanol may involve other sites on dopamine neurons or even different neurotransmitter systems, rather than the action of ethanol at the mesolimbic dopaminergic terminals. |
2003-07-11 |
2023-08-12 |
rat |
Robert Hitzemann, Barbara Hitzemann, Seth Rivera, John Gatley, Peter Thanos, Lu Lu Siming Shou, Robert W William. Dopamine D2 receptor binding, Drd2 expression and the number of dopamine neurons in the BXD recombinant inbred series: genetic relationships to alcohol and other drug associated phenotypes. Alcoholism, clinical and experimental research. vol 27. issue 1. 2003-07-01. PMID:12543998. |
it has not been established to what extent the natural variation in dopamine systems contribute to the variation in ethanol response. |
2003-07-01 |
2023-08-12 |
Not clear |
Robert Hitzemann, Barbara Hitzemann, Seth Rivera, John Gatley, Peter Thanos, Lu Lu Siming Shou, Robert W William. Dopamine D2 receptor binding, Drd2 expression and the number of dopamine neurons in the BXD recombinant inbred series: genetic relationships to alcohol and other drug associated phenotypes. Alcoholism, clinical and experimental research. vol 27. issue 1. 2003-07-01. PMID:12543998. |
the current study addresses this issue by measuring d2 dopamine (da) receptor binding, the expression of drd2, the number of midbrain da neurons in the bxd recombinant inbred (ri) series and then compares these strain means with those previously reported for a variety of ethanol and other drug-related phenotypes. |
2003-07-01 |
2023-08-12 |
Not clear |
Jilla Sabeti, Greg A Gerhardt, Nancy R Zahnise. Chloral hydrate and ethanol, but not urethane, alter the clearance of exogenous dopamine recorded by chronoamperometry in striatum of unrestrained rats. Neuroscience letters. vol 343. issue 1. 2003-07-01. PMID:12749985. |
chloral hydrate and ethanol, but not urethane, alter the clearance of exogenous dopamine recorded by chronoamperometry in striatum of unrestrained rats. |
2003-07-01 |
2023-08-12 |
rat |
Valentina Bassareo, Maria Antonietta De Luca, Marzia Aresu, Alessandra Aste, Teresa Ariu, Gaetano Di Chiar. Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713649. |
differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. |
2003-06-20 |
2023-08-12 |
human |
Valentina Bassareo, Maria Antonietta De Luca, Marzia Aresu, Alessandra Aste, Teresa Ariu, Gaetano Di Chiar. Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713649. |
in order to test this hypothesis, we compared in the same subject the effect of an addictive drug (ethanol) and of taste stimuli, including ethanol's own taste, on dialysate dopamine in the nucleus accumbens shell as an estimate of dopamine transmission and on taste reactivity as an expression of motivational valence. |
2003-06-20 |
2023-08-12 |
human |
Valentina Bassareo, Maria Antonietta De Luca, Marzia Aresu, Alessandra Aste, Teresa Ariu, Gaetano Di Chiar. Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713649. |
in contrast, intraoral infusion of 10% ethanol, 10% ethanol + 20% sucrose or 10% ethanol + 20% sucrose + chocolate solutions elicited a biphasic increase of nucleus accumbens dopamine with an early taste-related rise and a late rise related to dialysate ethanol. |
2003-06-20 |
2023-08-12 |
human |
Valentina Bassareo, Maria Antonietta De Luca, Marzia Aresu, Alessandra Aste, Teresa Ariu, Gaetano Di Chiar. Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713649. |
pre-exposure to the ethanol solutions 24 h before resulted in the absence of the early dopamine rise and permanence of the late dopamine rise. |
2003-06-20 |
2023-08-12 |
human |
Valentina Bassareo, Maria Antonietta De Luca, Marzia Aresu, Alessandra Aste, Teresa Ariu, Gaetano Di Chiar. Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713649. |
this late dopamine rise was actually increased as compared with that of the nonpre-exposed group when sucrose-containing ethanol solutions were tested. |
2003-06-20 |
2023-08-12 |
human |
Valentina Bassareo, Maria Antonietta De Luca, Marzia Aresu, Alessandra Aste, Teresa Ariu, Gaetano Di Chiar. Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713649. |
the results indicate that single trial pre-exposure to the ethanol solutions differentially affects the responsiveness of nucleus accumbens shell dopamine to the direct intracerebral action of ethanol and to the effect of its taste with potentiation, or no change of the first and abolition of the second. |
2003-06-20 |
2023-08-12 |
human |
Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
the present study examined the effects of intraperitoneal (ip) ethanol administration on the extracellular levels of dopamine in the ventral pallidum (vp) and globus pallidus (gp) of wistar rats. |
2003-06-11 |
2023-08-12 |
rat |
Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
the ip administration of 1.5 and 2.25 g/kg ethanol significantly (p <0.05) elevated the extracellular levels of dopamine in the vp (maximal increase: 136 and 182% of baseline, respectively) but not in the gp. |
2003-06-11 |
2023-08-12 |
rat |
Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
no effects on extracellular dopamine levels were observed following the ip injections of 0.75 g/kg ethanol or saline. |
2003-06-11 |
2023-08-12 |
rat |
Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
the ip administration of 2.25 g/kg ethanol significantly (p <0.05) elevated the extracellular levels of dopamine in the nac (maximal increase: 198% of baseline) and dstr (maximal increase: 155% of baseline). |
2003-06-11 |
2023-08-12 |
rat |
Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
analysis of the effects of 2.25 g/kg ethanol on dopamine release revealed greater increases in the vp, nac, and dstr compared to the gp. |
2003-06-11 |
2023-08-12 |
rat |