| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rose Milando, Adam Friedma. Cannabinoids: Potential Role in Inflammatory and Neoplastic Skin Diseases. American journal of clinical dermatology. vol 20. issue 2. 2019-07-31. PMID:30542832. |
the endocannabinoid system is a complex and nearly ubiquitous network of endogenous ligands, enzymes, and receptors that can also be stimulated by exogenous compounds such as those derived from the marijuana plant, cannabis sativa. |
2019-07-31 |
2023-08-13 |
Not clear |
| Rose Milando, Adam Friedma. Cannabinoids: Potential Role in Inflammatory and Neoplastic Skin Diseases. American journal of clinical dermatology. vol 20. issue 2. 2019-07-31. PMID:30542832. |
although legal restrictions on marijuana as a schedule i drug in the usa have made studying cannabinoid compounds unfavorable, an increasing number of studies and clinical trials have focused on the therapeutic uses of cannabinoids. |
2019-07-31 |
2023-08-13 |
Not clear |
| Yann Chye, Chao Suo, Valentina Lorenzetti, Albert Batalla, Janna Cousijn, Anna E Goudriaan, Rocio Martin-Santos, Sarah Whittle, Nadia Solowij, Murat Yüce. Cortical surface morphology in long-term cannabis users: A multi-site MRI study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 2. 2019-07-30. PMID:30558823. |
cannabis exerts its psychoactive effect through cannabinoid receptors that are widely distributed across the cortical surface of the human brain. |
2019-07-30 |
2023-08-13 |
human |
| Eric P Baro. Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. Headache. vol 58. issue 7. 2019-07-29. PMID:30152161. |
medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and cannabis science. |
2019-07-29 |
2023-08-13 |
Not clear |
| Carl R Lupica, Alexander F Hoffma. Cannabinoid disruption of learning mechanisms involved in reward processing. Learning & memory (Cold Spring Harbor, N.Y.). vol 25. issue 9. 2019-07-26. PMID:30115765. |
the increasing use of cannabis, its derivatives, and synthetic cannabinoids for medicinal and recreational purposes has led to burgeoning interest in understanding the addictive potential of this class of molecules. |
2019-07-26 |
2023-08-13 |
Not clear |
| Bruno M Fonseca, Renata Fernandes, Marta Almada, Márcia Santos, Félix Carvalho, Natércia A Teixeira, Georgina Correia-da-Silv. Synthetic cannabinoids and endometrial stromal cell fate: Dissimilar effects of JWH-122, UR-144 and WIN55,212-2. Toxicology. vol 413. 2019-07-25. PMID:30502353. |
the emergence of synthetic cannabinoids (scbs) as drugs of abuse in readily available "spice" smoking blends has exposed users to much more potent cannabinoids than the phytocannabinoids present in cannabis sativa l. increasing reports of adverse reactions are emerging in the clinical literature. |
2019-07-25 |
2023-08-13 |
human |
| Xiao Han, Yi He, Guo-Hua Bi, Hai-Ying Zhang, Rui Song, Qing-Rong Liu, Josephine M Egan, Eliot L Gardner, Jing Li, Zheng-Xiong X. CB1 Receptor Activation on VgluT2-Expressing Glutamatergic Neurons Underlies Δ Scientific reports. vol 7. issue 1. 2019-07-16. PMID:28951549. |
cannabis reward is believed to be mediated by activation of cannabinoid cb1 receptors (cb1rs) on gabaergic neurons that disinhibit dopaminergic neurons in the ventral tegmental area (vta). |
2019-07-16 |
2023-08-13 |
Not clear |
| Daniela Vergara, L Cinnamon Bidwell, Reggie Gaudino, Anthony Torres, Gary Du, Travis C Ruthenburg, Kymron deCesare, Donald P Land, Kent E Hutchison, Nolan C Kan. Compromised External Validity: Federally Produced Cannabis Does Not Reflect Legal Markets. Scientific reports. vol 7. 2019-07-15. PMID:28422145. |
our results demonstrate that the federally-produced cannabis has significantly less variety and lower concentrations of cannabinoids than are observed in state-legal u.s. dispensaries. |
2019-07-15 |
2023-08-13 |
Not clear |
| Tristan Dale, Jenny Downs, Heather Olson, Ann Marie Bergin, Stephanie Smith, Helen Leonar. Cannabis for refractory epilepsy in children: A review focusing on CDKL5 Deficiency Disorder. Epilepsy research. vol 151. 2019-07-12. PMID:30771550. |
the evidence supports the use of cannabinoids, especially cannabidiol, in similar forms of refractory epilepsy including dravet and lennox-gastaut syndromes. |
2019-07-12 |
2023-08-13 |
Not clear |
| Tristan Dale, Jenny Downs, Heather Olson, Ann Marie Bergin, Stephanie Smith, Helen Leonar. Cannabis for refractory epilepsy in children: A review focusing on CDKL5 Deficiency Disorder. Epilepsy research. vol 151. 2019-07-12. PMID:30771550. |
evidence for cannabinoids specifically in cdd is limited but growing, with multiple anecdotal reports and an open-label trial showing cannabidiol to be associated with a significant reduction in seizure activity. |
2019-07-12 |
2023-08-13 |
Not clear |
| Johannes R Popp, Eleftherios A Petrakis, Apostolis Angelis, Maria Halabalaki, Günther K Bonn, Hermann Stuppner, Leandros A Skaltsouni. Rapid isolation of acidic cannabinoids from Cannabis sativa L. using pH-zone-refining centrifugal partition chromatography. Journal of chromatography. A. vol 1599. 2019-07-10. PMID:31027757. |
rapid isolation of acidic cannabinoids from cannabis sativa l. using ph-zone-refining centrifugal partition chromatography. |
2019-07-10 |
2023-08-13 |
Not clear |
| Johannes R Popp, Eleftherios A Petrakis, Apostolis Angelis, Maria Halabalaki, Günther K Bonn, Hermann Stuppner, Leandros A Skaltsouni. Rapid isolation of acidic cannabinoids from Cannabis sativa L. using pH-zone-refining centrifugal partition chromatography. Journal of chromatography. A. vol 1599. 2019-07-10. PMID:31027757. |
this work introduces an effective methodology for the isolation of acidic cannabinoids from fiber-type cannabis sativa l. supercritical fluid extraction (sfe) was initially employed to obtain an enriched extract of acidic cannabinoids. |
2019-07-10 |
2023-08-13 |
Not clear |
| Sandra Blasco-Benito, Marta Seijo-Vila, Miriam Caro-Villalobos, Isabel Tundidor, Clara Andradas, Elena García-Taboada, Jeff Wade, Stewart Smith, Manuel Guzmán, Eduardo Pérez-Gómez, Mara Gordon, Cristina Sánche. Appraising the "entourage effect": Antitumor action of a pure cannabinoid versus a botanical drug preparation in preclinical models of breast cancer. Biochemical pharmacology. vol 157. 2019-07-08. PMID:29940172. |
extensive preclinical research has demonstrated that cannabinoids, the active ingredients of cannabis sativa, trigger antitumor responses in different models of cancer. |
2019-07-08 |
2023-08-13 |
Not clear |
| Gemma Navarro, Irene Reyes-Resina, Rafael Rivas-Santisteban, Verónica Sánchez de Medina, Paula Morales, Salvatore Casano, Carlos Ferreiro-Vera, Alejandro Lillo, David Aguinaga, Nadine Jagerovic, Xavier Nadal, Rafael Franc. Cannabidiol skews biased agonism at cannabinoid CB Biochemical pharmacology. vol 157. 2019-07-08. PMID:30194918. |
cannabidiol skews biased agonism at cannabinoid cb currently, biased agonism is at the center stage of drug development approaches. |
2019-07-08 |
2023-08-13 |
Not clear |
| Gemma Navarro, Irene Reyes-Resina, Rafael Rivas-Santisteban, Verónica Sánchez de Medina, Paula Morales, Salvatore Casano, Carlos Ferreiro-Vera, Alejandro Lillo, David Aguinaga, Nadine Jagerovic, Xavier Nadal, Rafael Franc. Cannabidiol skews biased agonism at cannabinoid CB Biochemical pharmacology. vol 157. 2019-07-08. PMID:30194918. |
we analyzed effects of a battery of cannabinoids plus/minus cannabidiol (cbd) in four functional parameters (camp levels, phosphorylation of extracellular signal-regulated kinases (erk1/2), β-arrestin recruitment and label-free/dmr) in hek-293t cells expressing cannabinoid receptors, cb |
2019-07-08 |
2023-08-13 |
Not clear |
| Atheer Zgair, Jong Bong Lee, Jonathan C M Wong, Dhiaa A Taha, Jehan Aram, Daisy Di Virgilio, Joshua W McArthur, Yu-Kit Cheng, Ivo M Hennig, David A Barrett, Peter M Fischer, Cris S Constantinescu, Pavel Gershkovic. Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. Scientific reports. vol 7. issue 1. 2019-07-05. PMID:29109461. |
oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. |
2019-07-05 |
2023-08-13 |
Not clear |
| Toni Leigh Mortimer, Tom Mabin, Anna-Mart Engelbrech. Cannabinoids: the lows and the highs of chemotherapy-induced nausea and vomiting. Future oncology (London, England). vol 15. issue 9. 2019-07-01. PMID:30720344. |
since cannabidiol does not induce psychotropic effects, in contrast to other cannabinoids, its use as an anti-emetic is of great interest. |
2019-07-01 |
2023-08-13 |
Not clear |
| Toni Leigh Mortimer, Tom Mabin, Anna-Mart Engelbrech. Cannabinoids: the lows and the highs of chemotherapy-induced nausea and vomiting. Future oncology (London, England). vol 15. issue 9. 2019-07-01. PMID:30720344. |
this review aims to summarize the available literature on cannabinoid use, with a specific focus on the nonpsychotropic drug cannabidiol, as well as the roles that cannabinoids play in preventing several other adverse side effects of chemotherapy including organ toxicity, pain and loss of appetite. |
2019-07-01 |
2023-08-13 |
Not clear |
| Joshua L Rein, Christina M Wyat. Marijuana and Cannabinoids in ESRD and Earlier Stages of CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 71. issue 2. 2019-06-27. PMID:28811049. |
marijuana and cannabinoids in esrd and earlier stages of ckd. |
2019-06-27 |
2023-08-13 |
Not clear |
| Iman Khuja, Zhanna Yekhtin, Reuven Or, Osnat Almogi-Haza. Cannabinoids Reduce Inflammation but Inhibit Lymphocyte Recovery in Murine Models of Bone Marrow Transplantation. International journal of molecular sciences. vol 20. issue 3. 2019-06-24. PMID:30720730. |
cannabinoids, the biologically active constituents of cannabis, have potent neuronal and immunological effects. |
2019-06-24 |
2023-08-13 |
mouse |