| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Soumitra Das, Annie Itrat, Mary Elizabeth Trejo Hernandez, Rasish Subedi, Thusanth Jogarajah, Sreshatha Vashist, Nikitha Daggal. Clozapine-induced eosinophilia: A case report. SAGE open medical case reports. vol 11. 2023-09-05. PMID:37667744. |
clozapine is one of the best atypical antipsychotics and is highly effective in treating treatment-resistant schizophrenia. |
2023-09-05 |
2023-09-07 |
Not clear |
| Janusz K Rybakowsk. Application of Antipsychotic Drugs in Mood Disorders. Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979224. |
the second-generation, so-called atypical antipsychotics (sgas), such as clozapine, risperidone, olanzapine, and quetiapine, have antimanic activity and are also effective for the maintenance treatment of bipolar disorder. |
2023-03-29 |
2023-08-14 |
human |
| Kouji Fukuyama, Eishi Motomura, Takashi Shiroyama, Motohiro Okad. Impact of 5-HT7 receptor inverse agonism of lurasidone on monoaminergic tripartite synaptic transmission and pathophysiology of lower risk of weight gain. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 148. 2022-02-26. PMID:35219120. |
these results suggest that effects of subchronic lurasidone administration on astroglial l-glutamate release, 5-ht receptor, and intracellular signalling are similar to vortioxetine and different from mood-stabilising atypical antipsychotics, clozapine. |
2022-02-26 |
2023-08-13 |
Not clear |
| Mina Y George, Esther T Menze, Ahmed Esmat, Mariane G Tadros, Ebtehal El-Demerdas. Naringin treatment improved main clozapine-induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosis. Drug development research. vol 82. issue 7. 2021-11-15. PMID:33537987. |
among them, clozapine is one of the atypical antipsychotics prescribed in schizophrenia wing to its blocking effect on dopamine (d2) and serotonin (5-ht |
2021-11-15 |
2023-08-13 |
rat |
| Leslie Citrome, Jan Volavk. Specific Anti-hostility Effects of Atypical Antipsychotics in Persons with Schizophrenia: From Clozapine to Cariprazine. Harvard review of psychiatry. vol 29. issue 1. 2021-10-25. PMID:33417374. |
specific anti-hostility effects of atypical antipsychotics in persons with schizophrenia: from clozapine to cariprazine. |
2021-10-25 |
2023-08-13 |
Not clear |
| Rohn Nahmias, David Pison, Areef Kassam, Dennis Anderso. Slow your role: How slowing clozapine titration can prevent recurrent NMS. Schizophrenia research. vol 218. 2021-06-17. PMID:31973998. |
in this case report, we discuss the importance of identifying atypical nms in patients treated with typical and atypical antipsychotics, and propose that successful treatment of these patients may be possible with slower and gradual titration of clozapine. |
2021-06-17 |
2023-08-13 |
Not clear |
| Chengfang Zhang, Xiaodan Wang, Chengping Hu, Wenhua Ding, Han Li, Meng Wu, Manji Hu, Qiang Wang, Xirong Su. The effect of prohibiting outside food during COVID-19 pandemic on the body weight of schizophrenic patients taking olanzapine or clozapine: a retrospective self-controlled study. Annals of palliative medicine. vol 10. issue 5. 2021-06-11. PMID:33894724. |
olanzapine and clozapine are atypical antipsychotics (aaps) with the greatest risk of weight gain, and changes in feeding behavior are among the most important underlying mechanisms. |
2021-06-11 |
2023-08-13 |
Not clear |
| Gulshan Begum, Stanley Nkemjika, Olaniyi Olayinka, Tolu Olupona, Ayodeji Jolayem. Clozapine Response for Vocal Tics in Schizophrenic Patients: A Case Report With Literature Review. Cureus. vol 13. issue 3. 2021-04-29. PMID:33907647. |
we suggest that clozapine augmentation therapy could be an approach in treatment-resistant vocal tics among schizophrenic patients who are refractory to atypical antipsychotics. |
2021-04-29 |
2023-08-13 |
Not clear |
| Karun Badwal, Shangwe A Kiliaki, Sagar B Dugani, Sandeep R Pagal. Psychosis Management in Lewy Body Dementia: A Comprehensive Clinical Approach. Journal of geriatric psychiatry and neurology. 2021-01-19. PMID:33461372. |
if addition of pharmacological agents is required, consideration should be given to acetylcholinesterase inhibitors, pimavanserin and atypical antipsychotics such as quetiapine or clozapine. |
2021-01-19 |
2023-08-13 |
Not clear |
| Mehran Zarghami, Seyed Davood Hoseini, Arash Kazemi, Forouzan Elyas. Concurrent Hepatotoxicity and Neutropenia Induced by Clozapine. Archives of Iranian medicine. vol 23. issue 2. 2021-01-06. PMID:32061077. |
clozapine is known as one of the atypical antipsychotics which is placed in the second line of medical treatment for schizophrenia due to its hematologic complications. |
2021-01-06 |
2023-08-13 |
Not clear |
| Giuseppe Caruso, Margherita Grasso, Annamaria Fidilio, Fabio Tascedda, Filippo Drago, Filippo Carac. Antioxidant Properties of Second-Generation Antipsychotics: Focus on Microglia. Pharmaceuticals (Basel, Switzerland). vol 13. issue 12. 2020-12-29. PMID:33322693. |
opposite to haloperidol, second-generation antipsychotics (or atypical antipsychotics) such as risperidone, clozapine, and olanzapine exert a strong antioxidant activity in experimental models of schizophrenia by rescuing the antioxidant system, with an increase in superoxide dismutase and glutathione (gsh) serum levels. |
2020-12-29 |
2023-08-13 |
Not clear |
| Sajid Hameed, Mukesh Kumar, Piyush Puri, Fnu Sapna, Pal Satyajit Singh Athwa. Consequences of a Missed History: A Case of Antidepressant Discontinuation Syndrome. Cureus. vol 12. issue 10. 2020-11-20. PMID:33209514. |
it is reported to occur with the use of different classes of antidepressants - selective serotonin reuptake inhibitor (ssri), monoamineoxidase inhibitor (maoi), tricyclic antidepressants (tcas), and atypical antipsychotics like risperidone, trazodone, clozapine, and venlafaxine. |
2020-11-20 |
2023-08-13 |
Not clear |
| Saeed Ahmed, Ali Mahmood Khan, Hema Madhuri Mekala, Hema Venigalla, Rizwan Ahmed, Amira Etman, Michael Esang, Mustafa Quresh. Combined use of electroconvulsive therapy and antipsychotics (both clozapine and non-clozapine) in treatment resistant schizophrenia: A comparative meta-analysis. Heliyon. vol 3. issue 11. 2020-10-01. PMID:29264404. |
to assess the relative efficacies of clozapine plus electroconvulsive therapy (ect) compared against non-clozapine typical and atypical antipsychotics plus ect for the treatment of "treatment resistant schizophrenia" (trs). |
2020-10-01 |
2023-08-13 |
Not clear |
| Siddharth Sarkar, Nitin Gupt. Drug information update. Atypical antipsychotics and neuroleptic malignant syndrome: nuances and pragmatics of the association. BJPsych bulletin. vol 41. issue 4. 2020-09-30. PMID:28811916. |
the clinical profile of nms caused by certain atypical antipsychotics such as clozapine has been reported to be considerably different from the nms produced by typical antipsychotics, with diaphoresis encountered more commonly, and rigidity and tremor encountered less frequently. |
2020-09-30 |
2023-08-13 |
Not clear |
| A Elif An\\xc4\\xb1l Ya\\xc4\\x9fc\\xc4\\xb1o\\xc4\\x9flu, Ayg\\xc3\\xbcn Ertu\\xc4\\x9frul, Ahmet Alp Karaka\\xc5\\x9fl\\xc4\\xb1, Esen A\\xc4\\x9fao\\xc4\\x9flu, Serta\\xc3\\xa7 Ak, Sevilay Karahan, M K\\xc3\\xa2z\\xc4\\xb1m Yaz\\xc4\\xb1c\\xc4\\xb. A comparative study of detection of myocarditis induced by clozapine: With and without cardiac monitoring. Psychiatry research. vol 279. 2020-03-31. PMID:31362146. |
diagnosis of schizoaffective disorder and use of concominant lithium, valproic acid and atypical antipsychotics were higher in patients with sdm, while clozapine dose titration was similar compared to the rest of the patients. |
2020-03-31 |
2023-08-13 |
Not clear |
| Lavanya P Sharma, Y C Janardhan Redd. Obsessive-compulsive disorder comorbid with schizophrenia and bipolar disorder. Indian journal of psychiatry. vol 61. issue Suppl 1. 2020-02-25. PMID:30745688. |
in addition, certain atypical antipsychotics, clozapine in particular are known to induce or worsen ocs in schizophrenia. |
2020-02-25 |
2023-08-13 |
Not clear |
| Man Li, Weiwen Wang, Lan Sun, Wei Du, Hao Zhou, Feng Sha. Chronic clozapine treatment improves the alterations of prepulse inhibition and BDNF mRNA expression in the medial prefrontal cortex that are induced by adolescent social isolation. Behavioural pharmacology. vol 30. issue 4. 2020-02-13. PMID:30157036. |
clozapine, one of the atypical antipsychotics, is widely used in the treatment of schizophrenia patients and in experimental studies. |
2020-02-13 |
2023-08-13 |
rat |
| Matthew A J Chedrawe, Scott P Holman, Anna-Claire Lamport, Turgay Akay, George S Robertso. Pioglitazone is superior to quetiapine, clozapine and tamoxifen at alleviating experimental autoimmune encephalomyelitis in mice. Journal of neuroimmunology. vol 321. 2019-10-03. PMID:29957391. |
recent evidence suggests that clozapine and quetiapine (atypical antipsychotics), tamoxifen (selective-estrogen receptor modulator) and pioglitazone (ppar\xce\xb3 agonist) may improve functional recovery in multiple sclerosis (ms). |
2019-10-03 |
2023-08-13 |
mouse |
| Stefano Aringhieri, Marco Carli, Shivakumar Kolachalam, Valeria Verdesca, Enrico Cini, Mario Rossi, Peter J McCormick, Giovanni U Corsini, Roberto Maggio, Marco Scarsell. Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences. Pharmacology & therapeutics. vol 192. 2019-09-23. PMID:29953902. |
the introduction of atypical antipsychotics (aaps) since the discovery of its prototypical drug clozapine has been a revolutionary pharmacological step for treating psychotic patients as these allow a significant recovery not only in terms of hospitalization and reduction in symptoms severity, but also in terms of safety, socialization and better rehabilitation in the society. |
2019-09-23 |
2023-08-13 |
Not clear |
| Carolyn B McNabb, Roger J Tait, Meghan E McIlwain, Valerie M Anderson, John Suckling, Robert R Kydd, Bruce R Russel. Functional network dysconnectivity as a biomarker of treatment resistance in schizophrenia. Schizophrenia research. vol 195. 2018-11-26. PMID:29042073. |
resting-state functional mri data were obtained from 17 healthy controls as well as individuals with schizophrenia who responded well to first-line atypical antipsychotics (first-line responders; flr, n=18), had failed at least two trials of antipsychotics but responded to clozapine (treatment-resistant schizophrenia; trs, n=18), or failed at least two trials of antipsychotics and a trial of clozapine (ultra-treatment-resistant schizophrenia; utrs, n=16). |
2018-11-26 |
2023-08-13 |
Not clear |