| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marius M Hoepe. Drug treatment of pulmonary arterial hypertension: current and future agents. Drugs. vol 65. issue 10. 2006-07-27. PMID:15977967. |
the increasing insight into the pathogenesis of pah opens several new therapeutic opportunities, which include vasoactive intestinal peptide, selective serotonin reuptake inhibitors, adrenomedullin and hmg-coa reductase inhibitors (statins). |
2006-07-27 |
2023-08-12 |
Not clear |
| Shirin Kordasti, Maria Sapnara, Evan A Thomas, Erik Lindstrom, Mikael Forsman, Joel C Bornstein, Henrik Sjöval. Effects of cholera toxin on the potential difference and motor responses induced by distension in the rat proximal small intestine in vivo. American journal of physiology. Gastrointestinal and liver physiology. vol 290. issue 5. 2006-07-13. PMID:16357061. |
in controls, distension increased pd, and this response was reduced by the neural blocker tetrodotoxin given serosally and the vasoactive intestinal peptide (vip) receptor antagonist [4cl-d-phe(6),leu(17)]vip (2 mug.min(-1).kg(-1) iv) but unaffected by the serotonin 5-ht(3) receptor antagonist granisetron, by the nicotinic receptor antagonist hexamethonium, by the muscarinic receptor antagonist atropine, or by the cyclooxygenase inhibitor indomethacin. |
2006-07-13 |
2023-08-12 |
rat |
| Shirin Kordasti, Maria Sapnara, Evan A Thomas, Erik Lindstrom, Mikael Forsman, Joel C Bornstein, Henrik Sjöval. Effects of cholera toxin on the potential difference and motor responses induced by distension in the rat proximal small intestine in vivo. American journal of physiology. Gastrointestinal and liver physiology. vol 290. issue 5. 2006-07-13. PMID:16357061. |
development of this state depends on 5-ht(3) receptors, vip receptors, and prostaglandin synthesis, whereas its maintenance depends on 5-ht(3) and nicotinic receptors but not vip receptors. |
2006-07-13 |
2023-08-12 |
rat |
| Giacomo Zaccone, Angela Mauceri, Salvatore Fasul. Neuropeptides and nitric oxide synthase in the gill and the air-breathing organs of fishes. Journal of experimental zoology. Part A, Comparative experimental biology. vol 305. issue 5. 2006-05-30. PMID:16506226. |
in addition, 5-ht, enkephalins and some neuropeptides, such as vip and pacap, seem to be nanc transmitter candidates in the fish gill and polypterid lung. |
2006-05-30 |
2023-08-12 |
Not clear |
| Fadi H Mourad, Kassem A Barada, Nadine A Bou Rached, Carmen I Khoury, Nayef E Saadé, Camille F Nassa. Inhibitory effect of experimental colitis on fluid absorption in rat jejunum: role of the enteric nervous system, VIP, and nitric oxide. American journal of physiology. Gastrointestinal and liver physiology. vol 290. issue 2. 2006-03-02. PMID:16123200. |
the effects of 1) tetrodotoxin (ttx), 2) benzylalkonium chloride (bac), 3) capsaicin, 4) vasoactive intestinal polypeptide (vip) antagonism, 5) nitric oxide (no) synthase (nos) inhibition, and 6) 5-hydroxytryptamine type 3 and 4 (5-ht(3) and 5-ht(4)) receptor antagonism on the changes in fluid movement were investigated. |
2006-03-02 |
2023-08-12 |
rat |
| Yuhki Sato, Shin Inoue, Fumihiko Katagiri, Hiroki Itoh, Masaharu Takeyam. Effects of pirenzepine on Dai-kenchu-to-induced elevation of the plasma neuropeptide levels in humans. Biological & pharmaceutical bulletin. vol 29. issue 1. 2006-02-22. PMID:16394532. |
we reported that dai-kenchu-to increases plasma neuropeptide [motilin, vasoactive intestinal polypeptide (vip), serotonin, calcitonin gene-related peptide (cgrp), and substance p]-like immunoreactive substances (is) levels and that its pharmacologic effects on the gastrointestine are due to changes in gastrointestinal mucosa-regulatory peptide levels. |
2006-02-22 |
2023-08-12 |
human |
| Inger Jansen-Olesen, Sergio Gulbenkian, Ulla Engel, Manuel Cunha e Sá, Lars Edvinsso. Peptidergic and non-peptidergic innervation and vasomotor responses of human lenticulostriate and posterior cerebral arteries. Peptides. vol 25. issue 12. 2005-06-07. PMID:15572198. |
in both arteries, the contractions induced by noradrenaline (na), npy and 5-hydroxytryptamine (5-ht) and the relaxant responses induced by acetylcholine (ach), vip and pituitary adenylate cyclase activating peptide-27 (pacap) as well as cgrp and sp were compared in vitro. |
2005-06-07 |
2023-08-12 |
human |
| I Rozenboim, N Mobarky, R Heiblum, Y Chaiseha, S W Kang, I Biran, A Rosenstrauch, D Sklan, M E El Halawan. The role of prolactin in reproductive failure associated with heat stress in the domestic turkey. Biology of reproduction. vol 71. issue 4. 2005-05-16. PMID:15201198. |
to test this hypothesis, laying female turkeys were subjected to 40 degrees c for 12 h during the photo-phase daily or maintained at 24-26 degrees c. birds in each group received oral treatment with parachlorophenyalanine (pcpa; 50 mg/kg bw/day for 3 days), an inhibitor of serotonin (5-ht) biosynthesis, or immunized against vasoactive intestinal peptide (vip). |
2005-05-16 |
2023-08-12 |
Not clear |
| V Mirochnik, O Bosler, Y Tillet, A Calas, M Ugrumo. Long-lasting effects of serotonin deficiency on differentiating peptidergic neurons in the rat suprachiasmatic nucleus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 23. issue 1. 2005-05-09. PMID:15730890. |
it is concluded that 5-ht provides long-lasting effects on differentiating vip and vp neurons in the scn resulting in attenuated release rather than elevated synthesis of both peptides in adulthood. |
2005-05-09 |
2023-08-12 |
rat |
| E C Seretis, N J Agnantis, V C Golematis, I E Voloudakis-Balatzi. Electron immunocytochemical demonstration of serotonin, vasoactive intestinal polypeptide, bombesin, somatostatin and glucagon in mirror biopsies from primary colorectal adenocarcinoma. Journal of experimental & clinical cancer research : CR. vol 23. issue 3. 2005-04-18. PMID:15595639. |
bombesin and vip appeared to be located in enterochromaffin-like (ecl) endocrine cells primarily responsible for the production of serotonin. |
2005-04-18 |
2023-08-12 |
Not clear |
| E C Seretis, N J Agnantis, V C Golematis, I E Voloudakis-Balatzi. Electron immunocytochemical demonstration of serotonin, vasoactive intestinal polypeptide, bombesin, somatostatin and glucagon in mirror biopsies from primary colorectal adenocarcinoma. Journal of experimental & clinical cancer research : CR. vol 23. issue 3. 2005-04-18. PMID:15595639. |
in conclusion, low somatostatin expression, high glucagon and serotonin expression and the ectopic secretion of vip and bombesin neuropeptides in mirror biopsies indicate the preneoplastic nature of these tissues and may be useful for the optimal treatment of patients with colorectal adenocarcinoma. |
2005-04-18 |
2023-08-12 |
Not clear |
| S Arrighi, F Cremonesi, G Bosi, C Domeneghin. Endocrine-paracrine cells of the male urogenital apparatus: a comparative histochemical and immunohistochemical study in some domestic ungulates. Anatomia, histologia, embryologia. vol 33. issue 4. 2004-10-28. PMID:15239814. |
immunoreactivities to chromogranin a, 5-hydroxytryptamine, somatostatin, [met]- and [leu]- enkephalins, gastrin-releasing peptide, calcitonin gene-related peptide, neuropeptide y, substance p, vasoactive intestinal peptide, beta-endorphin antisera were tested by a streptavidin-biotin method. |
2004-10-28 |
2023-08-12 |
Not clear |
| Robert Y Moore, Joan C Spe. Serotonin innervation of the primate suprachiasmatic nucleus. Brain research. vol 1010. issue 1-2. 2004-09-01. PMID:15126131. |
as in rodents, the distribution of the serotonin innervation of the primate scn overlaps that of the retinohypothalamic input and the vip neuronal population. |
2004-09-01 |
2023-08-12 |
human |
| V Simonneaux, J M Miguez, P Peve. Peptidergic modulation of serotonin release from cultured rat pinealocytes. Journal of neuroendocrinology. vol 9. issue 7. 2004-08-25. PMID:15305572. |
the peptides vasoactive intestinal peptide (vip) and pituitary adenylate cyclase activating peptide (pacap) up to 10(-7) m induced always a moderate (+20-30%) increase in intra- and extracellular levels of 5-ht. |
2004-08-25 |
2023-08-12 |
rat |
| V Simonneaux, J M Miguez, P Peve. Peptidergic modulation of serotonin release from cultured rat pinealocytes. Journal of neuroendocrinology. vol 9. issue 7. 2004-08-25. PMID:15305572. |
however, the use of nm concentrations of vip or pacap together with 10(-6) m iso induced a decrease in 5-ht outflow (-25-30%) and a dramatic increase in melatonin secretion as did 10(-5) m iso alone. |
2004-08-25 |
2023-08-12 |
rat |
| Gaëlle Boudry, Jean-Paul Lallès, Charles Henri Malbert, Marie Louise Grøndahl, Martin Andreas Unmack, Erik Skadhaug. Soybean impairs Na(+)-dependent glucose absorption and Cl- secretion in porcine small intestine. Reproduction, nutrition, development. vol 43. issue 5. 2004-07-22. PMID:15005370. |
the effect of the soybean products on camp-dependent cl- secretion was measured as the increase in isc after the addition of the phosphodiesterase inhibitor, theophylline, while nervous regulation of cl- secretion was investigated by the addition of the enteric neurotransmitters; 5-hydroxytryptamine (5-ht), substance p and vasoactive intestinal polypeptide (vip). |
2004-07-22 |
2023-08-12 |
Not clear |
| S Kordasti, H Sjövall, O Lundgren, L Svensso. Serotonin and vasoactive intestinal peptide antagonists attenuate rotavirus diarrhoea. Gut. vol 53. issue 7. 2004-07-16. PMID:15194642. |
serotonin and vasoactive intestinal peptide antagonists attenuate rotavirus diarrhoea. |
2004-07-16 |
2023-08-12 |
Not clear |
| S Kordasti, H Sjövall, O Lundgren, L Svensso. Serotonin and vasoactive intestinal peptide antagonists attenuate rotavirus diarrhoea. Gut. vol 53. issue 7. 2004-07-16. PMID:15194642. |
we now report that antagonists for the 5-hydroxytryptamine 3 receptor (5-ht(3)) and vasoactive intestinal peptide (vip) receptor, but not antagonists for 5-hydroxytryptamine 4 receptor or the muscarinic receptor, attenuate rotavirus induced diarrhoea. |
2004-07-16 |
2023-08-12 |
Not clear |
| S C Bischoff, S Schwengberg, A Lorentz, M P Manns, H Bektas, H Sann, F Levi-Schaffer, F Shanahan, M Scheman. Substance P and other neuropeptides do not induce mediator release in isolated human intestinal mast cells. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 16. issue 2. 2004-06-03. PMID:15086872. |
we found that sp at 0.1-100 micromol l(-1), or other peptides including neurokinin a and b, calcitonin gene-related peptide, vasoactive intestinal peptide and serotonin at 1 micromol l(-1) do not induce release of mediators such as histamine, sulphidoleukotrienes, and tumour necrosis factor alpha. |
2004-06-03 |
2023-08-12 |
human |
| Ana B F Emiliano, Julie L Fudg. From galactorrhea to osteopenia: rethinking serotonin-prolactin interactions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 5. 2004-05-25. PMID:14997175. |
alternate pathways involve serotonin stimulation of vasoactive intestinal peptide (vip) and oxytocin (ot) release. |
2004-05-25 |
2023-08-12 |
Not clear |