| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenjie Xu, Shanshan Xu, Ruobing Feng, Li Zen. Yunpi Tongbian Fang alleviates slow transit constipation induced by loperamide by regulating intestinal microbiota and short-chain fatty acids in rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 10. 2023-11-13. PMID:37953588. |
in addition, yptbf increased the concentrations of 5-ht and ache, while reducing the concentrations of vip and no. |
2023-11-13 |
2023-11-20 |
rat |
| Shasha Cheng, Baolei Li, Yixin Ding, Baochao Hou, Weilian Hung, Jian He, Yujun Jiang, Yu Zhang, Chaoxin Ma. The probiotic fermented milk of Lacticaseibacillus paracasei JY062 and Lactobacillus gasseri JM1 alleviates constipation via improving gastrointestinal motility and gut microbiota. Journal of dairy science. 2023-11-03. PMID:37923200. |
herein, after the intervention of probiotic fermented milk (fmmix) containing lacticaseibacillus paracasei jy062 and lactobacillus gasseri jm1 for 14 d in kunming mice with loperamide-induced constipation, the results indicated that fmmix significantly increased the secretion of serum motilin (mtl), gastrin (gas) and 5-hydroxytryptamine (5-ht) and decreased those of peptide yy (pyy), vasoactive intestinal peptide (vip) and nitric oxide (no) in mice. |
2023-11-03 |
2023-11-08 |
mouse |
| Chloë Lefèvre, Camille Le Roy, Anne Bessard, Catherine Le Berre-Scoul, Justine Marchix, Emmanuel Coron, Marc Le Rhun, Charlène Brochard, Brigitte Perrouin-Verbe, Michel Neunlis. Region-specific remodeling of the enteric nervous system and enteroendocrine cells in the colon of spinal cord injury patients. Scientific reports. vol 13. issue 1. 2023-10-06. PMID:37803037. |
while the vip concentration was similar in the right and left colons, vip mrna expression was increased in the right colon and decreased in the left colon, in sci patients as compared to ct. interestingly, 5-ht concentration was reduced in the left colon but not in the right colon in sci patients. |
2023-10-06 |
2023-10-15 |
Not clear |
| Chrisanthi Zouli, Eleana Zisimopoulou, Alexandra Chrisoulido. Biomarkers in neuroendocrine neoplasms. Hellenic journal of nuclear medicine. vol 26 Suppl. 2023-09-02. PMID:37658563. |
functional nens can be divided into carcinoid tumors, with serotonin overproduction, and functional gep nen's (mostly located in pancreas) that may secrete insulin, vip, gastrin, glucagon or somatostatin. |
2023-09-02 |
2023-09-07 |
Not clear |
| Qamar Sultana, Jill Kar, Amogh Verma, Shreya Sanghvi, Nirja Kaka, Neil Patel, Yashendra Sethi, Hitesh Chopra, Mohammad Amjad Kamal, Nigel H Grei. A Comprehensive Review on Neuroendocrine Neoplasms: Presentation, Pathophysiology and Management. Journal of clinical medicine. vol 12. issue 15. 2023-08-12. PMID:37568540. |
hormonal or non-hormonal biomarkers (like serum serotonin, urine 5-hiaa, gastrin and vip) and histology of a suspected nen is, therefore, critical for both confirmation of the diagnosis and classification as an net or nec. |
2023-08-12 |
2023-08-16 |
Not clear |
| Jing Li, Yike Sun, Ruochong Wang, Shuran Ma, Lei Shi, Kai Wang, Hairong Zhang, Tong Wang, Leilei Li. Seasonal differences in intestinal flora are related to rats' intestinal water metabolism. Frontiers in microbiology. vol 14. 2023-03-13. PMID:36910220. |
to explore the molecular mechanism of seasonal changes in intestinal water metabolism, the concentration of colonic 5-ht, vip, camp, and pka associated with intestinal water metabolism in rats were also examined. |
2023-03-13 |
2023-08-14 |
rat |
| Jing Li, Yike Sun, Ruochong Wang, Shuran Ma, Lei Shi, Kai Wang, Hairong Zhang, Tong Wang, Leilei Li. Seasonal differences in intestinal flora are related to rats' intestinal water metabolism. Frontiers in microbiology. vol 14. 2023-03-13. PMID:36910220. |
seasonal changes could affect the concentration of colonic 5-ht and vip in rats, and then regulate aqps through camp/pka pathway to affect the intestinal water metabolism. |
2023-03-13 |
2023-08-14 |
rat |
| Ying-Ying Huang, Ting Yang, Qi-Qi Wang, Jiang-Ling Long, Qin-Ru Li, Qi-Jian Xu, Ai-Hua Huang, Jin-Yu Wang, Quan Xi. [Dryness-alleviating effect of processed Aurantii Fructus from Lingnan based on correlation of fecal metabolomics and dryness]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 1. 2023-02-01. PMID:36725261. |
after seven days of administration, the effects of raf and paf on dryness-related indexes were compared, including water intake, fecal water content, salivary secretion, the expression of aqp5, vip, and 5-ht in the submandibular gland, as well as the expression of aqp3, vip, and 5-ht in the colon. |
2023-02-01 |
2023-08-14 |
rat |
| Ying-Ying Huang, Ting Yang, Qi-Qi Wang, Jiang-Ling Long, Qin-Ru Li, Qi-Jian Xu, Ai-Hua Huang, Jin-Yu Wang, Quan Xi. [Dryness-alleviating effect of processed Aurantii Fructus from Lingnan based on correlation of fecal metabolomics and dryness]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 1. 2023-02-01. PMID:36725261. |
moreover, paf could alleviate dryness of raf to a certain extent by reducing the water intake, fecal water content, and the expression of aqp3, vip, and 5-ht in the colon and increasing the salivary secretion and the levels of aqp5, vip, and 5-ht in the submandibular gland. |
2023-02-01 |
2023-08-14 |
rat |
| Qi Li, Huizhen She. Shengjing Runchang Decoction ameliorates spleen deficiency-induced constipation in children: An observational study. Medicine. vol 101. issue 51. 2023-01-03. PMID:36595853. |
the clinical efficacy and neurocytokines including 5-hydroxytryptamine (5-ht), vasoactive intestinal peptide (vip), children's colonic transit time (ctt), glial cell line-derived neurotrophic factor, colonic estrogen receptor before and after treatment were analyzed and compared between the 2 groups. |
2023-01-03 |
2023-08-14 |
Not clear |
| Qi Li, Huizhen She. Shengjing Runchang Decoction ameliorates spleen deficiency-induced constipation in children: An observational study. Medicine. vol 101. issue 51. 2023-01-03. PMID:36595853. |
the curative effect, total effective rate of tcm syndromes, ctt, 5-ht and plasma vip levels, glial cell-derived nerve effects of trophic factor levels, immune function igg, igga, cd4/cd8 in the treatment group were significantly promoted in comparison with the control group (p > .05). |
2023-01-03 |
2023-08-14 |
Not clear |
| Giampaolo Bosi, Barbara J Maynard, Flavio Pironi, Bahram Sayyaf Dezful. Parasites and the neuroendocrine control of fish intestinal function: an ancient struggle between pathogens and host. Parasitology. 2022-09-09. PMID:36076315. |
emphasis is on the occurrence of 21 molecules including cholecystokinin-8, neuropeptide y, enkephalins, galanin, vasoactive intestinal peptide and serotonin in infected tissues. |
2022-09-09 |
2023-08-14 |
Not clear |
| Jillena Zinsser-Krys, Christopher Kapitza, Lena Böhnke, Piet van der Keylen, Winfried L Neuhuber, Jürgen Wör. Neurochemical classification of serotonin-immunoreactive neurons co-innervating motor endplates in the mouse esophagus. Anatomical record (Hoboken, N.J. : 2007). 2022-07-15. PMID:35838072. |
then, co-localization of serotonin and vip was tested in co-innervating axons on motor endplates, which were visualized with α-bungarotoxin (α-bt) by multilabel immunofluorescence. |
2022-07-15 |
2023-08-14 |
mouse |
| Jillena Zinsser-Krys, Christopher Kapitza, Lena Böhnke, Piet van der Keylen, Winfried L Neuhuber, Jürgen Wör. Neurochemical classification of serotonin-immunoreactive neurons co-innervating motor endplates in the mouse esophagus. Anatomical record (Hoboken, N.J. : 2007). 2022-07-15. PMID:35838072. |
after co-staining with vip, we found (a) serotonin (5-ht)-positive nerve endings without vip (44% of 5-ht-positively innervated endplates), (b) 5-ht- and vip-positive endings without co-localization (35%), and (c) 5-ht- and vip-positive endings with co-localization (21%). |
2022-07-15 |
2023-08-14 |
mouse |
| Jia-Jun Wang, Jian-Mei Yuan, Li-Ying Wang, Yong Li, Mi-Hong Ren, Hong-Yan Li, Dao-Yin Gong, Jian Wan. [Mechanism of Huanglian Houpo Decoction in treatment of ulcerative colitis in mice based on brain-gut axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 11. 2022-06-19. PMID:35718528. |
based on the brain-gut axis, the present study investigated the effect of huanglian houpo decoction(hlhpd) in the treatment of ulcerative colitis(uc) and explored the mechanism in the regulation of 5-hydroxytryptamine(5-ht), substance p(sp), and vasoactive intestinal peptide(vip) using modern technologies and molecular docking. |
2022-06-19 |
2023-08-14 |
mouse |
| Jia-Jun Wang, Jian-Mei Yuan, Li-Ying Wang, Yong Li, Mi-Hong Ren, Hong-Yan Li, Dao-Yin Gong, Jian Wan. [Mechanism of Huanglian Houpo Decoction in treatment of ulcerative colitis in mice based on brain-gut axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 11. 2022-06-19. PMID:35718528. |
the expression of 5-ht, sp, vip, tumor necrosis factor α(tnf-α), interleukin-6(il-6), and interleukin-1β(il-1β) in the hypothalamus, serum, and colon was determined by the enzyme-linked immunosorbent assay(elisa). |
2022-06-19 |
2023-08-14 |
mouse |
| Jia-Jun Wang, Jian-Mei Yuan, Li-Ying Wang, Yong Li, Mi-Hong Ren, Hong-Yan Li, Dao-Yin Gong, Jian Wan. [Mechanism of Huanglian Houpo Decoction in treatment of ulcerative colitis in mice based on brain-gut axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 11. 2022-06-19. PMID:35718528. |
the high-and medium-dose hlhpd could significantly down-regulated sp and 5-ht in colon tissues and 5-ht in the serum, and up-regulated the vip in the serum. |
2022-06-19 |
2023-08-14 |
mouse |
| Jia-Jun Wang, Jian-Mei Yuan, Li-Ying Wang, Yong Li, Mi-Hong Ren, Hong-Yan Li, Dao-Yin Gong, Jian Wan. [Mechanism of Huanglian Houpo Decoction in treatment of ulcerative colitis in mice based on brain-gut axis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 11. 2022-06-19. PMID:35718528. |
the high-dose hlhpd group could down-regulate 5-ht and up-regulate vip in the hypothalamus. |
2022-06-19 |
2023-08-14 |
mouse |
| Sagar Dhoble, Vandana Patravale, Edward Weaver, Dimitrios A Lamprou, Tanmay Patraval. Comprehensive Review on Novel Targets and Emerging Therapeutic Modalities for Pulmonary Arterial Hypertension. International journal of pharmaceutics. 2022-05-05. PMID:35513217. |
this is followed by the newer disease targets expressed in the pathobiology of the disease like rho kinase pathway, vasoactive intestinal peptide pathway, receptor tyrosine kinases, serotonin signalling pathway, voltage-gated potassium (kv) channel pathway. |
2022-05-05 |
2023-08-13 |
Not clear |
| Hyeon-Jeong Yoon, Won-Hee Jang, Susun An, Yong Sok Ji, Kyung Chul Yoo. Tear Neuromediators in Subjects with and without Dry Eye According to Ocular Sensitivity. Chonnam medical journal. vol 58. issue 1. 2022-02-16. PMID:35169558. |
the concentrations of the tear neuromediators, including nerve growth factor (ngf), serotonin, calcitonin gene-related peptide (cgrp), substance p, neuropeptide y, and vasoactive intestinal peptide were measured using the enzyme-linked immune sorbent assay. |
2022-02-16 |
2023-08-13 |
human |