| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Ishine, J G Yu, Y Asada, T J Le. Nitric oxide is the predominant mediator for neurogenic vasodilation in porcine pial veins. The Journal of pharmacology and experimental therapeutics. vol 289. issue 1. 1999-04-21. PMID:10087030. |
this tetrodotoxin-sensitive relaxation was not affected by receptor antagonists for vip, cgrp, 5-ht, or sp but was blocked by l-glutamine (1 mm) and abolished by nomega-nitro-l-arginine (10 microm) and nomega-nitro-l-arginine methyl ester (10 microm). |
1999-04-21 |
2023-08-12 |
Not clear |
| L Jia, J S Stamle. Dual actions of S-nitrosylated derivative of vasoactive intestinal peptide as a vasoactive intestinal peptide-like mediator and a nitric oxide carrier. European journal of pharmacology. vol 366. issue 1. 1999-04-14. PMID:10064155. |
on rat gastric fundus, these compounds inhibited contraction amplitude and frequency induced with 5-hydroxytryptamine (5-ht) in the order of inhibitory potency vip > vipgc-no > vipgc > isoproterenol > gsno. |
1999-04-14 |
2023-08-12 |
rat |
| B Eto, M Boisset, B Griesmar, J F Desjeu. Effect of sorbin on electrolyte transport in rat and human intestine. The American journal of physiology. vol 276. issue 1. 1999-03-09. PMID:9886985. |
c7-sorbin (10(-3) m) inhibited the increase in isc induced by a series of 10 secretory agents such as secretin, vasoactive intestinal peptide, pge2, and serotonin. |
1999-03-09 |
2023-08-12 |
human |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on vascular and luminal release of serotonin from isolated perfused rat duodenum. Annals of the New York Academy of Sciences. vol 865. 1999-02-16. PMID:9928058. |
effect of vip and pacap on vascular and luminal release of serotonin from isolated perfused rat duodenum. |
1999-02-16 |
2023-08-12 |
rat |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on vascular and luminal release of serotonin from isolated perfused rat duodenum. Annals of the New York Academy of Sciences. vol 865. 1999-02-16. PMID:9928058. |
effects of cck, vip, pacap38, and pacap27 on the release of 5ht into the intestinal lumen and into the portal circulation were examined in in vivo experiments of isolated rat duodenum perfused vascularly and luminally. |
1999-02-16 |
2023-08-12 |
rat |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on vascular and luminal release of serotonin from isolated perfused rat duodenum. Annals of the New York Academy of Sciences. vol 865. 1999-02-16. PMID:9928058. |
vip, pacap 38 and 27 reduced the release of 5ht into the lumen but did not affect the vascular release of 5ht. |
1999-02-16 |
2023-08-12 |
rat |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on vascular and luminal release of serotonin from isolated perfused rat duodenum. Annals of the New York Academy of Sciences. vol 865. 1999-02-16. PMID:9928058. |
these effects were not affected by the presence of atropine, hexamethonium, or ttx, suggesting that vip, pacap 38 and 27 exert a direct inhibitory effect on the luminal release of 5ht from the ec cells. |
1999-02-16 |
2023-08-12 |
rat |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on vascular and luminal release of serotonin from isolated perfused rat duodenum. Annals of the New York Academy of Sciences. vol 865. 1999-02-16. PMID:9928058. |
nitric oxide synthase inhibitor, ng-nitro-l-arginine, antagonized the inhibitory effects of vip, pacap 38 and 27, suggesting that nitric oxide seems to be essential to exert the inhibitory action of vip and pacaps on the release of 5ht into the intestinal lumen from the ec cells. |
1999-02-16 |
2023-08-12 |
rat |
| J A Balsa, F Sánchez-Franco, F Pazos, J I Lara, M J Lorenzo, G Maldonado, L Caciced. Direct action of serotonin on prolactin, growth hormone, corticotropin and luteinizing hormone release in cocultures of anterior and posterior pituitary lobes: autocrine and/or paracrine action of vasoactive intestinal peptide. Neuroendocrinology. vol 68. issue 5. 1999-02-04. PMID:9822800. |
direct action of serotonin on prolactin, growth hormone, corticotropin and luteinizing hormone release in cocultures of anterior and posterior pituitary lobes: autocrine and/or paracrine action of vasoactive intestinal peptide. |
1999-02-04 |
2023-08-12 |
Not clear |
| J A Balsa, F Sánchez-Franco, F Pazos, J I Lara, M J Lorenzo, G Maldonado, L Caciced. Direct action of serotonin on prolactin, growth hormone, corticotropin and luteinizing hormone release in cocultures of anterior and posterior pituitary lobes: autocrine and/or paracrine action of vasoactive intestinal peptide. Neuroendocrinology. vol 68. issue 5. 1999-02-04. PMID:9822800. |
as we have previously shown that vasoactive intestinal peptide (vip) mediates through an autocrine or paracrine action the prl release induced by insulin-like growth factor i, thyrotropin-releasing hormone (trh) and dopamine withdrawal, the aim of the present work was to determine whether 5-ht has a direct action on pituitary secretion and to study the possible role of pituitary vip in this situation. |
1999-02-04 |
2023-08-12 |
Not clear |
| J A Balsa, F Sánchez-Franco, F Pazos, J I Lara, M J Lorenzo, G Maldonado, L Caciced. Direct action of serotonin on prolactin, growth hormone, corticotropin and luteinizing hormone release in cocultures of anterior and posterior pituitary lobes: autocrine and/or paracrine action of vasoactive intestinal peptide. Neuroendocrinology. vol 68. issue 5. 1999-02-04. PMID:9822800. |
vip release was also stimulated by 5-ht in the cocultures, and the time response profile was only similar to that of prl. |
1999-02-04 |
2023-08-12 |
Not clear |
| J A Balsa, F Sánchez-Franco, F Pazos, J I Lara, M J Lorenzo, G Maldonado, L Caciced. Direct action of serotonin on prolactin, growth hormone, corticotropin and luteinizing hormone release in cocultures of anterior and posterior pituitary lobes: autocrine and/or paracrine action of vasoactive intestinal peptide. Neuroendocrinology. vol 68. issue 5. 1999-02-04. PMID:9822800. |
in order to study whether pituitary vip is implicated in 5-ht action, cocultures preincubated with corticosterone were incubated in the presence of 5-ht, a vip-receptor antagonist (vip-at) or simultaneously with 5-ht plus vip-at. |
1999-02-04 |
2023-08-12 |
Not clear |
| J A Balsa, F Sánchez-Franco, F Pazos, J I Lara, M J Lorenzo, G Maldonado, L Caciced. Direct action of serotonin on prolactin, growth hormone, corticotropin and luteinizing hormone release in cocultures of anterior and posterior pituitary lobes: autocrine and/or paracrine action of vasoactive intestinal peptide. Neuroendocrinology. vol 68. issue 5. 1999-02-04. PMID:9822800. |
these data demostrate that: (1) 5-ht stimulates the secretion of prl, gh, acth, lh and vip acting directly at pituitary level on pp, probably by releasing an unidentified mediator from melanotropes; (2) glucocorticoids make the response of ap cells to 5-ht possible due to the presence of pp cells in the coculture; (3) prl response to 5-ht is mediated through an autocrine and/or paracrine action of vip. |
1999-02-04 |
2023-08-12 |
Not clear |
| S Arrighi, C Domeneghin. Immunolocalization of regulatory peptides and 5-HT in bovine male urogenital apparatus. Histology and histopathology. vol 13. issue 4. 1999-01-28. PMID:9810501. |
immunoreactivities to grp, met- and leu-enkephalins, cgrp, npy, substance p, vip, somatostatin, beta-endorphin and 5-ht antisera were tested by means of a labelled streptavidin-biotin (lsab) method. |
1999-01-28 |
2023-08-12 |
cattle |
| K Hanasawa, M Kodam. [Sepsis and organ failure--its pathogenesis and treatment]. Nihon Geka Gakkai zasshi. vol 99. issue 8. 1998-12-01. PMID:9789288. |
secondary mediators such as lipids (prostaglandin, thromboxane, platelet-activating factor), peptides (bradykinin, vasoactive intestinal peptide), amines (histamine, serotonin) and complements are key mediators which lead to the state of shock in human sepsis. |
1998-12-01 |
2023-08-12 |
human |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on basal release of serotonin from isolated vascularly and luminally perfused rat duodenum. The American journal of physiology. vol 275. issue 4. 1998-11-23. PMID:9756504. |
effect of vip and pacap on basal release of serotonin from isolated vascularly and luminally perfused rat duodenum. |
1998-11-23 |
2023-08-12 |
rat |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on basal release of serotonin from isolated vascularly and luminally perfused rat duodenum. The American journal of physiology. vol 275. issue 4. 1998-11-23. PMID:9756504. |
the effect of vasoactive intestinal polypeptide (vip), pituitary adenylate cyclase-activating peptide-38 (pacap-38), and pacap-27 on the release of serotonin (5-ht) into the intestinal lumen and the portal circulation was studied by using in vivo isolated vascularly and luminally perfused rat duodenum. |
1998-11-23 |
2023-08-12 |
rat |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on basal release of serotonin from isolated vascularly and luminally perfused rat duodenum. The American journal of physiology. vol 275. issue 4. 1998-11-23. PMID:9756504. |
vip, pacap-38, and pacap-27 reduced the luminal release of 5-ht but did not affect the vascular release of 5-ht. |
1998-11-23 |
2023-08-12 |
rat |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on basal release of serotonin from isolated vascularly and luminally perfused rat duodenum. The American journal of physiology. vol 275. issue 4. 1998-11-23. PMID:9756504. |
these results suggest that vip and pacap exert a direct inhibitory effect on the luminal release of 5-ht from the enterochromaffin (ec) cells via a common receptor site on the ec cells and that this effect is mediated by no but not by cholinergic pathways. |
1998-11-23 |
2023-08-12 |
rat |
| M Fujimiya, H Yamamoto, A Kuwahar. Effect of VIP and PACAP on basal release of serotonin from isolated vascularly and luminally perfused rat duodenum. The American journal of physiology. vol 275. issue 4. 1998-11-23. PMID:9756504. |
these results suggest that ec cells may receive the direct innervation of cholinergic neurons as well as vip and/or pacap neurons, with the former exerting a tonic stimulatory influence and the latter exerting a tonic inhibitory influence on 5-ht release into the intestinal lumen. |
1998-11-23 |
2023-08-12 |
rat |