Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yunfei Li, Xinying Zhou, Yusong Du, Mingyuan An, Shasha Wan, Zewei Sun, Qingzhen Zhon. Hesperidin facilitating gastrointestinal motility by "Gut-brain axis" and "SCF/C-Kit signaling pathways". Poultry science. vol 103. issue 12. 2024-10-22. PMID:39437558. |
incorporation of hesperidin into the broilers' diet significantly enhances serum levels of ghrelin, encompassing serotonin (5-ht), motilin (mtl), cholecystokinin (cck), and stem cell factor (scf) as well as substance p (sp) in the gizzard and duodenal tissues while reducing vasoactive intestinal peptide (vip) levels (p < 0.05). |
2024-10-22 |
2024-10-25 |
Not clear |
Jannes Boesenkoetter, Ina Ellrichmann, Björn Konukiewitz, Mark Ellrichmann, Dominik M Schult. Efficacy of Racecadotril in a Patient Affected by a Therapy-Refractory VIPoma and Carcinoid Syndrome. JCEM case reports. vol 2. issue 10. 2024-10-01. PMID:39351119. |
we present the case of a 49-year-old male patient affected by an oligo-metastatic ileal nen, concurrently demonstrating vasointestinal peptide (vip) and serotonin excretion, complicated by pulmonary tuberculosis. |
2024-10-01 |
2024-10-03 |
Not clear |
Beilei Xu, Shengnan Chen, Jingjing Liu, Di Wu, Wenbin Sun, Shusen Liu, Yang Hu, Hao Wang, Jinhong Wang, Bo Yang, Wenlan Li, Shuangcheng M. Anti-LSSDS pharmacological components identification of YuHuangLian based on the combination of spectrum-effect analysis and network pharmacology as well as molecular docking. Biomedical chromatography : BMC. 2024-09-25. PMID:39318149. |
vasoactive intestinal peptide (vip), substance p, and 5-ht levels in colon sample were measured by elisa. |
2024-09-25 |
2024-09-27 |
Not clear |
Marianna Franchina, Federica Cavalcoli, Olga Falco, Marta La Milia, Alessandra Elvevi, Sara Massiron. Biochemical Markers for Neuroendocrine Tumors: Traditional Circulating Markers and Recent Development-A Comprehensive Review. Diagnostics (Basel, Switzerland). vol 14. issue 12. 2024-06-27. PMID:38928704. |
specific circulating markers such as serotonin and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) and various gastrointestinal hormones such as gastrin, glucagon, somatostatin, and vasoactive intestinal peptide (vip) have a role in identifying functional nens. |
2024-06-27 |
2024-06-29 |
Not clear |
Xiaolei Yang, Hongjie Li, Chao Yang, Jie G. Supplementation with stigma maydis polysaccharide attenuates autism-like behaviors and improves gut function in valproic acid-induced autism model male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2024-06-26. PMID:38923604. |
furthermore, the expression levels of neurotransmitters (substance p, enkephalin, vasoactive intestinal peptide, and 5-hydroxytryptamine) in the hippocampal tissues were altered after smps treatment. |
2024-06-26 |
2024-06-29 |
rat |
Ting Yang, Jia-Min Feng, Ding-Kun Zhang, Xue Li, Peng Tan, Jun-Zhi Lin, Run-Chun X. [Comparative analysis of efficacy of different forms of Galli Gigerii Endothelium Corneum on functional dyspepsia in rats based on composition-pharmacodynamics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 10. 2024-05-30. PMID:38812170. |
the results showed that both powder and decoction significantly increased the gastric emptying effect, small intestinal propulsion rate, digestive enzymes activity, gastrin(gas), motilin(mtl), ghrelin(ghrl) and reduced vasoactive intestinal peptide(vip), 3-(2-ammo-nioethyl)-5-hydroxy-1h-indolium maleate(5-ht), and somatostatin(sst) content in rats(p<0.05, p<0.01). |
2024-05-30 |
2024-06-17 |
rat |
Ting Yang, Jia-Min Feng, Ding-Kun Zhang, Xue Li, Peng Tan, Jun-Zhi Lin, Run-Chun X. [Comparative analysis of efficacy of different forms of Galli Gigerii Endothelium Corneum on functional dyspepsia in rats based on composition-pharmacodynamics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 10. 2024-05-30. PMID:38812170. |
comparison of ggec decoction and powder administration between groups of the same dosage level showed that gastrointestinal propulsion and serum levels of gas, ghrl, vip, and sst in the powder group were significantly superior to those in the decoction and that the gastrointestinal propulsion, as well as serum levels of mtl, gas, and ghrl were slightly higher than those of the decoction with two times its raw dose, and the serum levels of sst, 5-ht, and vip in the powder group were slightly lower than those of the decoction with two times its raw dose. |
2024-05-30 |
2024-06-17 |
rat |
Cristina Llorent. The Imperative for Innovative Enteric Nervous System-Intestinal Organoid Co-Culture Models: Transforming GI Disease Modeling and Treatment. Cells. vol 13. issue 10. 2024-05-24. PMID:38786042. |
neurotransmitters, including acetylcholine (ach), serotonin (5-ht), and vasoactive intestinal peptide (vip), play pivotal roles in these intricate interactions. |
2024-05-24 |
2024-05-27 |
Not clear |
L I Ruibai, Chen Ke, M A Wei, Zhang Yayue, Hou Li, Chen Xiny. Hemostatic mechanism of Jianpi Yiqi Shexue decoction in treatment of immune thrombocytopenia. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 44. issue 3. 2024-05-20. PMID:38767638. |
to explore the early hemostatic mechanism of jianpi yiqi shexue decoction (, jysd) in treating immune thrombocytopathy (itp), based on the functional homeostasis of brain-intestine axis and blood neurotransmitter methods: non-drug treatment cases: healthy volunteers were selected as normal control group and compared with patients with dysfunctional uterine bleeding, gastrointestinal tumors with bleeding and itp, to detect the changes of blood 5-hydroxytryptamine (5-ht), β-endorphin (β-ep), vasoactive intestinal peptide (vip) and compare the changes of blood neuro-transmitters in patients with different disease symptoms. |
2024-05-20 |
2024-05-27 |
human |
L I Ruibai, Chen Ke, M A Wei, Zhang Yayue, Hou Li, Chen Xiny. Hemostatic mechanism of Jianpi Yiqi Shexue decoction in treatment of immune thrombocytopenia. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. vol 44. issue 3. 2024-05-20. PMID:38767638. |
the changes of blood neuro-transmitter (5-ht, β-ep, vip) before and after treatment were detected on the basis of peripheral blood platelet (plt) and grade score. |
2024-05-20 |
2024-05-27 |
human |
Yuan Deng, Qiong Zhao, Hong-Yun Zhou, Zi-Qi Zhang, Yu Zha. Activation of ASIC3/ERK pathway by paeoniflorin improves intestinal fluid metabolism and visceral sensitivity in slow transit constipated rats. The Kaohsiung journal of medical sciences. 2024-04-18. PMID:38634140. |
pf treatment not only attenuated compound diphenoxylate-induced constipation symptoms and colonic pathological damage in rats but also ameliorated colonic fluid metabolic disorders and visceral sensitization abnormalities, as manifested by increased colonic goblet cell counts and mucin2 protein expression, decreased aquaporin3 protein expression, improved abdominal withdrawal reflex scores, reduced visceral pain threshold, upregulated serum 5-hydroxytryptamine, and downregulated vasoactive intestinal peptide levels. |
2024-04-18 |
2024-04-20 |
rat |
Yong Wen, Yu Zhan, Taiyu Chen, Jun Li, Qing Long, Fan Zheng, Shiyu Tang, Xuegui Tan. Total Flavonoids of Aurantii Fructus Immaturus Regulate miR-5100 to Improve Constipation by Targeting Fzd2 to Alleviate Calcium Balance and Autophagy in Interstitial Cells of Cajal. Molecular neurobiology. 2024-01-20. PMID:38244148. |
furthermore, afif increased the levels of sp, 5-ht, and vip, and increased the expression of pgp9.5, sy, and cx43, which alleviated constipation by improving the integrity of the enteric nervous system network. |
2024-01-20 |
2024-01-23 |
mouse |
Li Cui, Yongzhi Hua, Shuting Zou, Chao Gu, Hui L. Combination of fenchone and sodium hyaluronate ameliorated constipation-predominant irritable bowel syndrome and underlying mechanisms. Chemical biology & drug design. vol 103. issue 1. 2024-01-17. PMID:38030381. |
the neurotransmitter levels, including substance p (sp), motilin (mtl), 5-hydroxytryptamine (5-ht), and vasoactive intestinal peptide (vip), were determined by elisa methods. |
2024-01-17 |
2024-01-19 |
rat |
Hui Yu, Huiqian Deng, Wei Zhou, Zhenling Lian. Effects of electroacupuncture combined with acupoint catgut embedding on gastrointestinal motility and gastrointestinal hormones in rats with functional dyspepsia. The Chinese journal of physiology. vol 66. issue 6. 2023-12-27. PMID:38149565. |
gastric emptying rate (ger) and intestinal propulsive ratio (ipr) were measured in each group, and serum gastrointestinal hormone (motilin [mtl], leptin, gastrin [gas], vasoactive intestinal peptide [vip], calcitonin gene-related peptide [cgrp], and somatostatin [ss]) levels, oxidative stress factors (superoxide dismutase [sod] and malondialdehyde [mda]) and 5-hydroxytryptamine (5-ht) levels were also measured. |
2023-12-27 |
2023-12-29 |
rat |
Hui Yu, Huiqian Deng, Wei Zhou, Zhenling Lian. Effects of electroacupuncture combined with acupoint catgut embedding on gastrointestinal motility and gastrointestinal hormones in rats with functional dyspepsia. The Chinese journal of physiology. vol 66. issue 6. 2023-12-27. PMID:38149565. |
serum mtl, gas, ss, and sod levels were reduced, and serum leptin, vip, cgrp, mda, and 5-ht levels were increased in rats of the model group in comparison to the control group. |
2023-12-27 |
2023-12-29 |
rat |
Hui Yu, Huiqian Deng, Wei Zhou, Zhenling Lian. Effects of electroacupuncture combined with acupoint catgut embedding on gastrointestinal motility and gastrointestinal hormones in rats with functional dyspepsia. The Chinese journal of physiology. vol 66. issue 6. 2023-12-27. PMID:38149565. |
elevated mean body weight, paw mechanical pain threshold, food intake, ger and ipr, and serum mtl, gas, ss, and sod levels, and reduced serum leptin, vip, cgrp, mda, and 5-ht levels were observed in rats of the ea, ace, and ea + ace groups relative to the model group. |
2023-12-27 |
2023-12-29 |
rat |
Yi-Ming Li, Gui-Mei Lin, Yuan-Pan Yu, Yi Ya. [A comparative study of raw Aurantii Fructus Immaturus and bran-fried products on dryness of rats with slow-transit constipation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114148. |
the levels of camp/cgmp, vip, 5-ht, aqp1, and aqp5 were measured in each group with drug treatment, and the expression of c-kit and scf mrna in gastric antrum tissue and aqp3 mrna in the kidney and colon were detected by rt-pcr. |
2023-12-19 |
2023-12-23 |
rat |
Yi-Ming Li, Gui-Mei Lin, Yuan-Pan Yu, Yi Ya. [A comparative study of raw Aurantii Fructus Immaturus and bran-fried products on dryness of rats with slow-transit constipation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 20. 2023-12-19. PMID:38114148. |
the fd and fg groups had a more significant impact on c-kit, scf, vip, 5-ht, and other gastrointestinal motility indicators than the sd and sg groups. |
2023-12-19 |
2023-12-23 |
rat |
Yi Xiao, Jing-Ying Zhou, Hong-Zhi Yin, Qian Liu, Rong Luo, Wei-Ai Liu, Ge-Shu DU, Huan Zhong, Mi Li. Effect of electroacupuncture at "Neiguan" (PC 6) and "Zusanli" (ST 36) on gastrointestinal hormone in the antral tissue of rats with functional dyspepsia. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 43. issue 12. 2023-12-13. PMID:38092545. |
to observe the effects of electroacupuncture (ea) at "neiguan" (pc 6) and "zusanli"(st 36) on the gastric emptying rate, the level of serotonin (5-ht) and the protein expression of motilin (mtl), ghrelin, substance p (sp) and vasoactive intestinal peptide (vip) in the antral tissue of the rats with functional dyspepsia (fd) and explore the effect mechanism of ea in treatment of fd. |
2023-12-13 |
2023-12-17 |
rat |
Dhananjaya Pratap Singh, Sudarshan Maurya, Suresh Reddy Yerasu, Mansi Singh Bisen, Mohamed A Farag, Ratna Prabha, Renu Shukla, Krishna Kumar Chaturvedi, Md Samir Farooqi, Sudhir Srivastava, Anil Rai, Birinchi Kumar Sarma, Nagendra Rai, Tusar Kanti Beher. Metabolomics of early blight (Alternaria solani) susceptible tomato (Solanum lycopersicum) unfolds key biomarker metabolites and involved metabolic pathways. Scientific reports. vol 13. issue 1. 2023-12-01. PMID:38030710. |
opls-da model based on variable importance in projection (vip scores) and fc threshold (> 2.0) revealed 41 up regulated discriminant metabolite features annotated as sphingosine, fecosterol, melatonin, serotonin, glucose 6-phosphate, zeatin, dihydrozeatin and zeatin-β-d-glucoside. |
2023-12-01 |
2023-12-10 |
Not clear |