| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Häppölä, H Päivärinta, S Soinila, J Y Wu, P Panul. Localization of L-glutamate decarboxylase and GABA transaminase immunoreactivity in the sympathetic ganglia of the rat. Neuroscience. vol 21. issue 1. 1987-08-05. PMID:3299141. |
in consecutive sections, the small glutamate decarboxylase-immunoreactive cell clusters also showed immunoreactivity to tyrosine hydroxylase, suggesting that these cells contain the enzymes for both gaba and catecholamine synthesis. |
1987-08-05 |
2023-08-11 |
rat |
| T Kosaka, K Kosaka, Y Hataguchi, I Nagatsu, J Y Wu, O P Ottersen, J Storm-Mathisen, K Ham. Catecholaminergic neurons containing GABA-like and/or glutamic acid decarboxylase-like immunoreactivities in various brain regions of the rat. Experimental brain research. vol 66. issue 1. 1987-07-01. PMID:2884126. |
the coexistence of immunoreactivities for tyrosine hydroxylase (th) and glutamic acid decarboxylase (gad) and/or gamma-aminobutyric acid (gaba) was revealed in various brain regions in colchicine-injected and untreated rats, using the peroxidase-antiperoxidase method. |
1987-07-01 |
2023-08-11 |
rat |
| K Kosaka, K Hama, I Nagatsu, J Y Wu, O P Ottersen, J Storm-Mathisen, T Kosak. Postnatal development of neurons containing both catecholaminergic and GABAergic traits in the rat main olfactory bulb. Brain research. vol 403. issue 2. 1987-05-20. PMID:2881609. |
postnatal development of catecholaminergic and gamma-aminobutyric acid (gaba)-ergic neurons in the periglomerular region of the rat main olfactory bulb was studied immunohistochemically using antisera against tyrosine hydroxylase (th), glutamic acid decarboxylase and gaba. |
1987-05-20 |
2023-08-11 |
rat |
| T J Millar, I Ishimoto, M Boelen, M L Epstein, C D Johnson, I G Morga. The toxic effects of ethylcholine mustard aziridinium ion on cholinergic cells in the chicken retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 7. issue 2. 1987-04-01. PMID:2880936. |
retinas were also examined using histofluorescence for dopamine histochemistry, for ache, and immunohistochemistry with antibodies to cat, tyrosine hydroxylase, gaba, 5-ht, leu-enkephalin, and somatostatin. |
1987-04-01 |
2023-08-11 |
cat |
| A N van den Po. Tyrosine hydroxylase immunoreactive neurons throughout the hypothalamus receive glutamate decarboxylase immunoreactive synapses: a double pre-embedding immunocytochemical study with particulate silver and HRP. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 3. 1986-05-08. PMID:2870143. |
in the same areas where frequent tyrosine hydroxylase immunoreactive neurons were found, many axons and bouton terminals were also found with antisera against gaba or against the gaba-synthesizing enzyme glutamate decarboxylase. |
1986-05-08 |
2023-08-11 |
Not clear |
| T Kosaka, Y Hataguchi, K Hama, I Nagatsu, J Y W. Coexistence of immunoreactivities for glutamate decarboxylase and tyrosine hydroxylase in some neurons in the periglomerular region of the rat main olfactory bulb: possible coexistence of gamma-aminobutyric acid (GABA) and dopamine. Brain research. vol 343. issue 1. 1985-11-06. PMID:2864104. |
coexistence of immunoreactivities for glutamate decarboxylase and tyrosine hydroxylase in some neurons in the periglomerular region of the rat main olfactory bulb: possible coexistence of gamma-aminobutyric acid (gaba) and dopamine. |
1985-11-06 |
2023-08-11 |
rat |
| b' H H Hennies, W A G\\xc3\\xbcnzler, L Floh\\xc3\\xa. Influence of supidimide on brain neurotransmitter systems of rats and mice. Arzneimittel-Forschung. vol 34. issue 11. 1985-03-14. PMID:6084511.' |
with the above restrictions, the following parameters can be rated as not influenced by supidimide: levels of tryptophan in rat brain and serum (free and total); 5-ht biosynthesis in vivo (rat brain; 5-ht accumulation after monoamine oxidase (mao) blockade); activity of mao-a and mao-b (rat brain mitochondria); uptake of 5-ht, ne and da (rat synaptosomes); 5-ht receptor binding ( [3h]-lsd binding assay in rat cortical membranes); tyrosine hydroxylase activity (rat adrenal glands); catechol-o-methyl transferase (comt) (rat liver); ne binding to central alpha 1- and alpha 2-receptors (rat brain; radioligand assay with [3h]-dihydroergocryptine, [3h]-prazosin and [3h]-wb 4101 (2',6'-dimethoxy-(g-3h]-phenoxy]-ethylaminomethylbenzo-1,4-dioxane ); da levels (whole rat brain and striata); dihydroxyphenylacetic acid (dopac) levels (whole rat brain without cerebellum and striata); elevated dopac levels after pretreatment with haloperidol; da-dependent adenylate cyclase in vitro (rat striatum); d2 receptor binding ( [3h]-spiperone binding assay, rat striatum); gaba levels (mouse brain); gaba transaminase activity (mouse brain stem); sodium-independent [3h]-gaba receptor binding (rat brain) and benzodiazepine binding (rat cortical membranes, [3h]-diazepam binding assay). |
1985-03-14 |
2023-08-12 |
mouse |
| G N Babu, E Vijaya. Hypothalamic tyrosine hydroxylase activity, plasma gonadotropin and prolactin levels after aminooxyacetic acid in ovariectomized rats. Experientia. vol 40. issue 12. 1985-02-15. PMID:6150866. |
plasma concentrations of gonadotropin, prolactin and hypothalamic tyrosine hydroxylase (th) activity were measured in ovariectomized rats treated with aminooxyacetic acid (aoaa), a drug which elevates brain gaba levels. |
1985-02-15 |
2023-08-12 |
rat |
| A Berod, M Chat, L Paut, M Tappa. Catecholaminergic and GABAergic anatomical relationship in the rat substantia nigra, locus coeruleus, and hypothalamic median eminence: immunocytochemical visualization of biosynthetic enzymes on serial semithin plastic-embedded sections. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 32. issue 12. 1985-01-17. PMID:6150057. |
after partial removal of the resin and a light proteolytic treatment of the tissue we were able to localize several biosynthetic enzymes: tyrosine hydroxylase (th), phenylethanolamine n-methyltransferase (pnmt), and glutamic acid decarboxylase (gad), which are, respectively, markers of catecholaminergic, adrenergic, gamma-aminobutyric acid (gaba)ergic systems. |
1985-01-17 |
2023-08-12 |
rat |
| E Mugnaini, W H Oertel, F F Wouterloo. Immunocytochemical localization of GABA neurons and dopamine neurons in the rat main and accessory olfactory bulbs. Neuroscience letters. vol 47. issue 3. 1984-10-15. PMID:6147797. |
immunocytochemical localization of gaba neurons and dopamine neurons in the rat olfactory bulb was obtained with sheep antiserum to glutamate decarboxylase (gad) and rabbit antiserum to tyrosine hydroxylase (th). |
1984-10-15 |
2023-08-12 |
rat |
| T L Perry, F Javoy-Agid, Y Agid, H C Fibige. Striatal GABAergic neuronal activity is not reduced in Parkinson's disease. Journal of neurochemistry. vol 40. issue 4. 1983-05-05. PMID:6131932. |
the content of gamma-aminobutyric acid (gaba) and the activities of glutamic acid decarboxylase (gad) and tyrosine hydroxylase (th) were measured in whole putamen obtained at autopsy from 13 patients dying with idiopathic parkinson's disease and 13 appropriate control subjects. |
1983-05-05 |
2023-08-12 |
human |
| R B Rastogi, S K Rastogi, Y D Lapierre, R L Singha. Bromocriptine-induced changes in dopamine and gamma aminobutyric acid in haloperidol withdrawn rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 6. issue 4-6. 1983-04-07. PMID:6891811. |
while haloperidol withdrawal decreased tyrosine hydroxylase activity, it produced no further change in glutamic acid decarboxylase activity and gamma-aminobutyric acid. |
1983-04-07 |
2023-08-12 |
rat |
| H S Singer, J T Coyle, D L Weaver, N Kawamura, H J Bake. Neurotransmitter chemistry in feline GM1 gangliosidosis: a model for human ganglioside storage disease. Annals of neurology. vol 12. issue 1. 1982-10-29. PMID:6126152. |
assays for synaptosomal high-affinity uptake activity (glutamate, gamma-aminobutyric acid, norepinephrine), neurotransmitter synthesizing enzymes (choline acetyltransferase, glutamate decarboxylase, tyrosine hydroxylase), and endogenous neurotransmitters were performed in cats with advanced inherited gm1 gangliosidosis. |
1982-10-29 |
2023-08-12 |
human |
| M V Johnston, R Haddad, A Carman-Young, J T Coyl. Neurotransmitter chemistry of lissencephalic cortex induced in ferrets by fetal treatment with methylazoxymethanol acetate. Brain research. vol 256. issue 3. 1982-10-21. PMID:6125249. |
neurochemical analysis of 5 areas of cortex from 8-week-old offspring of mam- or vehicle-treated jills indicated an overall enrichment in markers for catecholaminergic (tyrosine hydroxylase, norepinephrine) and cholinergic (choline acetyltransferase, acetylcholine) terminals but minimal change in the concentration of gabaergic markers (glutamate decarboxylase, gamma-aminobutyric acid); however, there did not appear to be a direct, inverse relationship between the concentration of catecholaminergic and cholinergic markers and the degree of hypoplasia in cortical subareas unlike what has been found previously in the rat. |
1982-10-21 |
2023-08-12 |
rat |
| F Javoy-Agid, A Ploska, Y Agi. Microtopography of tyrosine hydroxylase, glutamic acid decarboxylase, and choline acetyltransferase in the substantia nigra and ventral tegmental area of control and Parkinsonian brains. Journal of neurochemistry. vol 37. issue 5. 1982-01-28. PMID:6117604. |
tyrosine hydroxylase (th), glutamic acid decarboxylase (gad), and choline acetyl transferase (cat) were used as markers for catecholamine, gamma-aminobutyric acid, and acetylcholine containing neurons in human mesencephalon. |
1982-01-28 |
2023-08-12 |
human |
| K Gal. Relationship between the presence of dopaminergic neurons and GABA receptors in substantia nigra: effects of lesions. Brain research. vol 210. issue 1-2. 1981-07-23. PMID:6112044. |
submaximal destruction of nigrostriatal dopaminergic projections resulted in a significant (25%) decrease in specific gaba binding in substantia nigra; under these conditions, striatal tyrosine hydroxylase activity was 15-44% of control. |
1981-07-23 |
2023-08-12 |
rat |
| K Gal. Relationship between the presence of dopaminergic neurons and GABA receptors in substantia nigra: effects of lesions. Brain research. vol 210. issue 1-2. 1981-07-23. PMID:6112044. |
in rats with lesions which caused maximal destruction of nigrostriatal dopamine neurons (striatal tyrosine hydroxylase was less than 15% of control), specific gaba binding in substantia nigra was apparently not different from that obtained in intact controls. |
1981-07-23 |
2023-08-12 |
rat |
| A Hotchkiss, J W Gib. Blockade of methamphetamine-induced depression of tyrosine hydroxylase by GABA transaminase inhibitors. European journal of pharmacology. vol 66. issue 2-3. 1981-02-24. PMID:6108224. |
blockade of methamphetamine-induced depression of tyrosine hydroxylase by gaba transaminase inhibitors. |
1981-02-24 |
2023-08-12 |
rat |
| A J Hotchkiss, J W Gib. Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain. The Journal of pharmacology and experimental therapeutics. vol 214. issue 2. 1980-09-28. PMID:6104722. |
agents which prevent the meth-induced decrease of neostriatal tyrosine hydroxylase activity, i.e., haloperidol, alpha-methyl-p-tyrosine and gamma-aminobutyric acid transaminase inhibitors also prevented the decrease in tph activity caused by meth. |
1980-09-28 |
2023-08-12 |
rat |
| J De Belleroche, Y Lugmani, H F Bradfor. Evidence for presynaptic cholinergic receptors on dopaminergic terminals: degeneration studies with 6-hydroxydopamine. Neuroscience letters. vol 11. issue 2. 1979-09-27. PMID:460689. |
intraventricular injections of 6-hydroxydopamine (6-ohda) caused a significant decrease in the tyrosine hydroxylase of striatal synaptosomes of rats, without influencing gaba levels. |
1979-09-27 |
2023-08-11 |
rat |