| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lai Zhang, Fengzhi Ding, Zhongyuan Ren, Weili Cheng, He Dai, Qing Liang, Fanling Kong, Wenjing Xu, Yuqing Zhang, Qin Ta. Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TNNI3 c.235C > T variant. International journal of cardiology. 2024-10-19. PMID:39426416. |
mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated tnni3 c.235c > t variant. |
2024-10-19 |
2024-10-22 |
Not clear |
| Natsuko Inagaki, Tomoya Okano, Masatake Kobayashi, Masatsune Fujii, Yoshinao Yazaki, Yasuyoshi Takei, Hisanori Kosuge, Shinji Suzuki, Takeharu Hayashi, Masahiko Kuroda, Kazuhiro Satom. Pediatric hypertrophic cardiomyopathy caused by a novel TNNI3 variant. Human genome variation. vol 11. issue 1. 2024-03-29. PMID:38548731. |
tnni3 is a gene that causes hypertrophic cardiomyopathy (hcm). |
2024-03-29 |
2024-03-31 |
Not clear |
| Natsuko Inagaki, Tomoya Okano, Masatake Kobayashi, Masatsune Fujii, Yoshinao Yazaki, Yasuyoshi Takei, Hisanori Kosuge, Shinji Suzuki, Takeharu Hayashi, Masahiko Kuroda, Kazuhiro Satom. Pediatric hypertrophic cardiomyopathy caused by a novel TNNI3 variant. Human genome variation. vol 11. issue 1. 2024-03-29. PMID:38548731. |
pediatric hypertrophic cardiomyopathy caused by a novel tnni3 variant. |
2024-03-29 |
2024-03-31 |
Not clear |
| Shane Rui Zhao, Mengcheng Shen, Chelsea Lee, Yanjun Zha, Julio V Guevara, Matthew T Wheeler, Joseph C W. Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying TNNI3 mutations. Stem cell research. vol 57. 2021-12-09. PMID:34798544. |
generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying tnni3 mutations. |
2021-12-09 |
2023-08-13 |
Not clear |
| Francesco Cava, Ernesto Cristiano, Maria Beatrice Musumeci, Camilla Savio, Aldo Germani, Maria Lo Monaco, Simona Petrucci, Maria Rosaria Torrisi, Camillo Autore, Speranza Rubattu, Maria Pian. TNNI3 and KCNQ1 co-inherited variants in a family with hypertrophic cardiomyopathy and long QT phenotypes: A case report. Molecular genetics and metabolism reports. vol 27. 2021-03-30. PMID:33777698. |
tnni3 and kcnq1 co-inherited variants in a family with hypertrophic cardiomyopathy and long qt phenotypes: a case report. |
2021-03-30 |
2023-08-13 |
Not clear |
| Ji-Won Hwang, Mi-Ae Jang, Shin Yi Jang, Soo Hyun Seo, Moon-Woo Seong, Sung Sup Park, Chang-Seok Ki, Duk-Kyung Ki. Diverse Phenotypic Expression of Cardiomyopathies in a Family with TNNI3 p.Arg145Trp Mutation. Korean circulation journal. vol 47. issue 2. 2020-09-30. PMID:28382084. |
here, we present the case of a large family, in which a single tnni3 mutation caused variable phenotypic expression, ranging from restrictive cardiomyopathy (rcmp) to hypertrophic cardiomyopathy (hcmp) to near-normal phenotype. |
2020-09-30 |
2023-08-13 |
Not clear |
| L Q Duan, Q Li, Y Ren, J R Xu, Q H Ha. [A Chinese pedigree with hypertrophic cardiomyopathy caused by rare homozygous mutation of TNNI3 gene p.Arg162Gln]. Zhonghua xin xue guan bing za zhi. vol 47. issue 12. 2020-02-13. PMID:31877599. |
[a chinese pedigree with hypertrophic cardiomyopathy caused by rare homozygous mutation of tnni3 gene p.arg162gln]. |
2020-02-13 |
2023-08-13 |
Not clear |
| Yue Zhao, Hong Cao, Yindi Song, Yue Feng, Xiaoxue Ding, Mingjie Pang, Yunmei Zhang, Hong Zhang, Jiahuan Ding, Xueshan Xi. Identification of novel mutations including a double mutation in patients with inherited cardiomyopathy by a targeted sequencing approach using the Ion Torrent PGM system. International journal of molecular medicine. vol 37. issue 6. 2017-02-28. PMID:27082122. |
in the present study, the entire coding sequences and flanking regions of 12 major disease (cardiomyopathy)-related genes [namely myosin, heavy chain 7, cardiac muscle, β (myh7); myosin binding protein c, cardiac (mybpc3); lamin a/c (lmna); troponin i type 3 (cardiac) (tnni3); troponin t type 2 (cardiac) (tnnt2); actin, α, cardiac muscle 1 (actc1); tropomyosin 1 (α) (tpm1); sodium channel, voltage gated, type v alpha subunit (scn5a); myosin, light chain 2, regulatory, cardiac, slow (myl2); myosin, heavy chain 6, cardiac muscle, α (myh6); myosin, light chain 3, alkali, ventricular, skeletal, slow (myl3); and protein kinase, amp-activated, gamma 2 non-catalytic subunit (prkag2)] in 8 patients with dilated cardiomyopathy (dcm) and in 8 patients with hypertrophic cardiomyopathy (hcm) were amplified and then sequenced using the ion torrent personal genome machine (pgm) system. |
2017-02-28 |
2023-08-13 |
human |
| Hua Zheng, Huajie Huang, Zhisong Ji, Qi Yang, Qiuxia Yu, Fan Shen, Cuixian Liu, Fu Xion. A Double Heterozygous Mutation of TNNI3 Causes Hypertrophic Cardiomyopathy in a Han Chinese Family. Cardiology. vol 133. issue 2. 2016-09-15. PMID:26506446. |
to investigate the variations in the tnni3 gene in a chinese han family affected by hypertrophic cardiomyopathy (hcm) and the potential molecular mechanism linking these mutations with disease. |
2016-09-15 |
2023-08-13 |
Not clear |
| Hua Zheng, Huajie Huang, Zhisong Ji, Qi Yang, Qiuxia Yu, Fan Shen, Cuixian Liu, Fu Xion. A Double Heterozygous Mutation of TNNI3 Causes Hypertrophic Cardiomyopathy in a Han Chinese Family. Cardiology. vol 133. issue 2. 2016-09-15. PMID:26506446. |
a double heterozygous mutation of tnni3 causes hypertrophic cardiomyopathy in a han chinese family. |
2016-09-15 |
2023-08-13 |
Not clear |
| Jomien M Mouton, Adriano S Pellizzon, Althea Goosen, Craig J Kinnear, Philip G Herbst, Paul A Brink, Johanna C Moolman-Smoo. Diagnostic disparity and identification of two TNNI3 gene mutations, one novel and one arising de novo, in South African patients with restrictive cardiomyopathy and focal ventricular hypertrophy. Cardiovascular journal of Africa. vol 26. issue 2. 2016-02-22. PMID:25940119. |
diagnostic disparity and identification of two tnni3 gene mutations, one novel and one arising de novo, in south african patients with restrictive cardiomyopathy and focal ventricular hypertrophy. |
2016-02-22 |
2023-08-13 |
Not clear |
| Xiefan Fang, Jourdon Robinson, John Wang-Hu, Lingli Jiang, Daniel A Freeman, Scott A Rivkees, Christopher C Wendle. cAMP induces hypertrophy and alters DNA methylation in HL-1 cardiomyocytes. American journal of physiology. Cell physiology. vol 309. issue 6. 2015-12-04. PMID:26224577. |
elevated camp levels increased cell size and altered expression levels of cardiac genes and micro-rnas associated with hypertrophic cardiomyopathy (hcm), including myh6, myh7, myh7b, tnni3, anp, bnp, gata4, mef2c, mef2d, nfatc1, mir208a, and mir208b. |
2015-12-04 |
2023-08-13 |
mouse |
| Nam Nhut Phan, Chih-Yang Wang, Yen-Chang Li. The novel regulations of MEF2A, CAMKK2, CALM3, and TNNI3 in ventricular hypertrophy induced by arsenic exposure in rats. Toxicology. vol 324. 2014-10-30. PMID:25089838. |
collectively, based on our real-time pcr and western blot data strongly suggest that calcium homeostasis may also go through mef2a, tnni3, camkk2, calm3 and cardiac hypertrophy relative signaling pathway. |
2014-10-30 |
2023-08-13 |
rat |
| Nam Nhut Phan, Chih-Yang Wang, Yen-Chang Li. The novel regulations of MEF2A, CAMKK2, CALM3, and TNNI3 in ventricular hypertrophy induced by arsenic exposure in rats. Toxicology. vol 324. 2014-10-30. PMID:25089838. |
the novel regulations of mef2a, camkk2, calm3, and tnni3 in ventricular hypertrophy induced by arsenic exposure in rats. |
2014-10-30 |
2023-08-13 |
rat |
| Lucía Núñez, Juan Ramón Gimeno-Blanes, María Isabel Rodríguez-García, Lorenzo Monserrat, Esther Zorio, Caroline Coats, Christopher G McGregor, Juan Pedro Hernandez del Rincón, Alfonso Castro-Beiras, Manuel Hermida-Priet. Somatic MYH7, MYBPC3, TPM1, TNNT2 and TNNI3 mutations in sporadic hypertrophic cardiomyopathy. Circulation journal : official journal of the Japanese Circulation Society. vol 77. issue 9. 2014-04-07. PMID:23782526. |
somatic myh7, mybpc3, tpm1, tnnt2 and tnni3 mutations in sporadic hypertrophic cardiomyopathy. |
2014-04-07 |
2023-08-12 |
Not clear |
| Deepa Selvi Rani, Pratibha Nallari, Singh Priyamvada, Calambur Narasimhan, Lalji Singh, Kumarasamy Thangara. High prevalence of Arginine to Glutamine substitution at 98, 141 and 162 positions in Troponin I (TNNI3) associated with hypertrophic cardiomyopathy among Indians. BMC medical genetics. vol 13. 2013-01-14. PMID:22876777. |
high prevalence of arginine to glutamine substitution at 98, 141 and 162 positions in troponin i (tnni3) associated with hypertrophic cardiomyopathy among indians. |
2013-01-14 |
2023-08-12 |
Not clear |
| A van den Wijngaard, P Volders, J P Van Tintelen, J D H Jongbloed, M P van den Berg, R H Lekanne Deprez, M M A M Mannens, N Hofmann, M Slegtenhorst, D Dooijes, M Michels, Y Arens, R Jongbloed, B J M Smeet. Recurrent and founder mutations in the Netherlands: cardiac Troponin I (TNNI3) gene mutations as a cause of severe forms of hypertrophic and restrictive cardiomyopathy. Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation. vol 19. issue 7-8. 2011-11-10. PMID:21533915. |
recurrent and founder mutations in the netherlands: cardiac troponin i (tnni3) gene mutations as a cause of severe forms of hypertrophic and restrictive cardiomyopathy. |
2011-11-10 |
2023-08-12 |
Not clear |
| Sebastian Carballo, Paul Robinson, Robyn Otway, Diane Fatkin, Jan D H Jongbloed, Nicolaas de Jonge, Edward Blair, J Peter van Tintelen, Charles Redwood, Hugh Watkin. Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy. Circulation research. vol 105. issue 4. 2009-09-22. PMID:19590045. |
one contractile protein gene well known as a hypertrophic cardiomyopathy disease gene, but with no reported mutation in autosomal dominant dcm, is tnni3 which encodes cardiac troponin i. |
2009-09-22 |
2023-08-12 |
Not clear |
| Mónica García-Castro, Eliecer Coto, Julián R Reguero, José R Berrazueta, Victoria Alvarez, Belén Alonso, Rocío Sainz, María Martín, Cesar Morí. [Mutations in sarcomeric genes MYH7, MYBPC3, TNNT2, TNNI3, and TPM1 in patients with hypertrophic cardiomyopathy]. Revista espanola de cardiologia. vol 62. issue 1. 2009-05-01. PMID:19150014. |
our aim was to determine the frequency of mutations in the sarcomeric genes myh7, mybpc3, tnnt2, tnni3, and tpm1 in a cohort of spanish patients with hypertrophic cardiomyopathy. |
2009-05-01 |
2023-08-12 |
Not clear |
| Mónica García-Castro, Eliecer Coto, Julián R Reguero, José R Berrazueta, Victoria Alvarez, Belén Alonso, Rocío Sainz, María Martín, Cesar Morí. [Mutations in sarcomeric genes MYH7, MYBPC3, TNNT2, TNNI3, and TPM1 in patients with hypertrophic cardiomyopathy]. Revista espanola de cardiologia. vol 62. issue 1. 2009-05-01. PMID:19150014. |
[mutations in sarcomeric genes myh7, mybpc3, tnnt2, tnni3, and tpm1 in patients with hypertrophic cardiomyopathy]. |
2009-05-01 |
2023-08-12 |
Not clear |