| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dominic Osei, Eveline Baumgart-Vogt, Barbara Ahlemeyer, Christiane Herde. Tumor Necrosis Factor-α Receptor 1 Mediates Borna Disease Virus 1-Induced Changes in Peroxisomal and Mitochondrial Dynamics in Neurons. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339126. |
using different mouse lines-i.e., tumor necrosis factor-α transgenic (tnftg; to pro-inflammatory status), tnf receptor-1 knockout (tnfr1ko), and tnfr2ko mice in comparison to wild-type (wt) mice-we analyzed the abundances of both organelles and their main antioxidant enzymes, catalase and superoxide dismutase 2 (sod2), in neurons of the hippocampal, cerebral, and cerebellar cortices. |
2024-02-10 |
2024-02-12 |
mouse |
| Amir Raoofi, Ali Delbari, Davood Nasiry, Rahim Golmohammadi, Sara Sadat Javadinia, Reza Sadrzadeh, Mohammad-Shafi Mojadadi, Auob Rustamzadeh, Amin Mousavi Khaneghah, Vahid Ebrahimi, Mohammad Jafar Rezai. Caffeine modulates apoptosis, oxidative stress, and inflammation damage induced by tramadol in cerebellum of male rats. Journal of chemical neuroanatomy. 2022-06-06. PMID:35660069. |
at the end of study (day 21), after performing rotarod behavioral test, cerebellum tissue samples were removed and prepared for further evaluations including biochemical profile markers (mda, gpx, and sod), immunohistochemistry for caspase-3, as well as the expression of genes involved in cellular processes such as inflammation markers (il-1β, hmgb1, il-6, and tnf), apoptosis markers (caspase-3, caspase-8, bax, and p21), and autophagy markers (lamp2, atg5, becn1, and atg12). |
2022-06-06 |
2023-08-14 |
rat |
| Kanishk Luhach, Giriraj T Kulkarni, Vijay P Singh, Bhupesh Sharm. Effect of papaverine on developmental hyperserotonemia induced autism spectrum disorder related behavioural phenotypes by altering markers of neuronal function, inflammation, and oxidative stress in rats. Clinical and experimental pharmacology & physiology. vol 48. issue 4. 2021-07-13. PMID:33480092. |
also, effects on important biochemical markers related with neuronal function (brain-derived neurotrophic factor (bdnf)-neuronal survival and phosphorylated-camp response element binding protein (pcreb)-neuronal transcription factor), brain inflammation (interleukin (il)-6, il-10 and tumour necrosis factor (tnf)-α) and brain oxidative stress (tbars and gsh) were studied in important brain areas (frontal cortex, cerebellum, hippocampus and striatum). |
2021-07-13 |
2023-08-13 |
rat |
| Patricia Gallego-Delgado, Rachel James, Eleanor Browne, Joanna Meng, Swetha Umashankar, Li Tan, Carmen Picon, Nicholas D Mazarakis, A Aldo Faisal, Owain W Howell, Richard Reynold. Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier. PLoS biology. vol 18. issue 12. 2021-02-02. PMID:33315860. |
we show that tumour necrosis factor (tnf), ifnγ, and glutamate can provoke paranodal elongation in cerebellar slice cultures, which could be reversed by an n-methyl-d-aspartate (nmda) receptor blocker. |
2021-02-02 |
2023-08-13 |
Not clear |
| Shaimaa N Amin, Sherif S Hassan, Ahmed S Khashaba, Magdy F Youakim, Noha S Abdel Latif, Laila A Rashed, Hanan D Yass. Hippocampal and Cerebellar Changes in Acute Restraint Stress and the Impact of Pretreatment with Ceftriaxone. Brain sciences. vol 10. issue 4. 2020-09-28. PMID:32218213. |
the biochemical analyses included measurements of serum cortisol, tumor necrotic factor (tnf), interleukin-6, hippocampal expression of bone morphogenetic protein 9 (bmp9), lysosomal-associated membrane protein 1 (lamp1), glutamate transporter 1 (glt1), heat shock protein 90, cerebellar expression of s100 protein, glutamic acid decarboxylase (gad), and carbon anhydrase. |
2020-09-28 |
2023-08-13 |
mouse |
| Yu-Ting Liao, Shih-Min Wang, Shun-Hua Che. Anti-inflammatory and antiviral effects of minocycline in enterovirus 71 infections. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 118. 2020-02-05. PMID:31377467. |
minocycline inhibited il-6 and granulocyte colony-stimulating factor (g-csf) in plasma and tnf in the cerebellum. |
2020-02-05 |
2023-08-13 |
mouse |
| Asha Mathew, Janelle M P Pakan, Estelle C Collin, Wenxin Wang, Kieran W McDermott, Una Fitzgerald, Richard Reynolds, Abhay S Pandi. An ex-vivo multiple sclerosis model of inflammatory demyelination using hyperbranched polymer. Biomaterials. vol 34. issue 23. 2014-02-04. PMID:23660252. |
tnf and ifnγ expression and release in cerebellar slices via non-viral gene delivery approach resulted in inflammation mediated myelin loss, thus making it a promising ex-vivo approach for studying the underlying mechanisms of demyelination in myelin-related diseases such as ms. |
2014-02-04 |
2023-08-12 |
Not clear |
| V V Kolobov, Z I Storozheva, M A Gruden, V V Sherstne. Regional features of the expression of genes involved in neurogenesis and apoptosis in the brain of adult rats. Bulletin of experimental biology and medicine. vol 153. issue 5. 2013-03-12. PMID:23113275. |
the expression of mrna of genes involved in neurogenesis and apoptosis (apaf1, ascl1, bax, bcl2, casp3, casp8, casp9, dffb, myh10, naip2, napa, notch2, numb, pura, s100a6, tnf) in the prefrontal cortex, hippocampus, and cerebellum was studied in adult rats. |
2013-03-12 |
2023-08-12 |
rat |
| S Tapia-González, Lhav M García-Segura, M Tena-Sempere, L M Frago, J M Castellano, E Fuente-Martín, C García-Cáceres, J Argente, J A Chowe. Activation of microglia in specific hypothalamic nuclei and the cerebellum of adult rats exposed to neonatal overnutrition. Journal of neuroendocrinology. vol 23. issue 4. 2011-07-21. PMID:21314736. |
there was no change in circulating tumour necrosis factor (tnf) α levels or tnfα mrna levels in either the hypothalamus or cerebellum. |
2011-07-21 |
2023-08-12 |
rat |
| K Kemp, D Gordon, D C Wraith, E Mallam, E Hartfield, J Uney, A Wilkins, N Scoldin. Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells. Neuropathology and applied neurobiology. vol 37. issue 2. 2011-04-29. PMID:20819172. |
in addition, we examined whether tumour necrosis factor (tnf)-alpha and interferon (ifn)-gamma, factors associated with inflammation, increase cellular fusion between human mscs and rodent cerebellar neurons in vitro. |
2011-04-29 |
2023-08-12 |
mouse |
| Andreas Beineke, Stefanie Markus, Jürgen Borlak, Thomas Thum, Wolfgang Baumgärtne. Increase of pro-inflammatory cytokine expression in non-demyelinating early cerebral lesions in nervous canine distemper. Viral immunology. vol 21. issue 4. 2009-01-29. PMID:19115929. |
using semi-quantitative reverse transcriptase polymerase chain reaction (rt-pcr), expression of pro- and anti-inflammatory cytokines such as interleukin (il)-1beta, il-2, il-6, il-8, il-10, il-12, tumor necrosis factor-alpha (tnf)-alpha, interferon (ifn)-gamma, and transforming growth factor (tgf)-beta were studied in the cerebra of distemper dogs with white matter lesions in the cerebellum. |
2009-01-29 |
2023-08-12 |
Not clear |
| Sławomir Michalak, Mieczysław Wender, Grazyna Michałowska-Wende. Cachexia--induced cerebellar degeneration: involvement of serum TNF and MCP-1 in the course of experimental neoplastic disease. Acta neurobiologiae experimentalis. vol 66. issue 2. 2006-09-08. PMID:16886721. |
cachexia--induced cerebellar degeneration: involvement of serum tnf and mcp-1 in the course of experimental neoplastic disease. |
2006-09-08 |
2023-08-12 |
rat |
| H Armah, A K Dodoo, E K Wiredu, J K Stiles, A A Adjei, R K Gyasi, Y Tette. High-level cerebellar expression of cytokines and adhesion molecules in fatal, paediatric, cerebral malaria. Annals of tropical medicine and parasitology. vol 99. issue 7. 2006-03-07. PMID:16212798. |
immunohistochemistry was therefore used to compare the expression of icam-1, vcam-1, e-selectin, il-1beta, tnf and transforming growth factor beta (tgf-beta) at light-microscope level, in cryostat sections of cerebral, cerebellar and brainstem tissues collected, post-mortem, from ghanaian children. |
2006-03-07 |
2023-08-12 |
human |
| Brian M Berg, Jonathan P Godbout, Jing Chen, Keith W Kelley, Rodney W Johnso. alpha-Tocopherol and selenium facilitate recovery from lipopolysaccharide-induced sickness in aged mice. The Journal of nutrition. vol 135. issue 5. 2005-07-06. PMID:15867297. |
regardless of diet, interleukin (il)-6, il-1beta, and tumor necrosis factor (tnf)alpha mrna levels were elevated by lps approximately 3-fold in cortex, cerebellum, striatum, and hippocampus. |
2005-07-06 |
2023-08-12 |
mouse |
| Bertha A León-Chávez, Juan Antonio Gonzalez-Barrios, Araceli Ugarte, Marco A Meraz, Daniel Martinez-Fon. Evidence in vitro of glial cell priming in the taiep rat. Brain research. vol 965. issue 1-2. 2003-05-01. PMID:12591146. |
cultured glial cells from the cerebellum of 15-day-old taiep rats produced no, increased inos levels, up-regulated inos expression and promoted tnf release when stimulated with lps and ifngamma. |
2003-05-01 |
2023-08-12 |
rat |
| S Busquets, B Alvarez, M Van Royen, M T Figueras, F J López-Soriano, J M Argilé. Increased uncoupling protein-2 gene expression in brain of lipopolysaccharide-injected mice: role of tumour necrosis factor-alpha? Biochimica et biophysica acta. vol 1499. issue 3. 2001-05-21. PMID:11341972. |
an increase in ucp2 gene expression was also observed after lps treatment in double knockout mice for tumour necrosis factor-alpha (tnf) receptors 1 and 2 (75% in brain and 33% in cerebellum). |
2001-05-21 |
2023-08-12 |
mouse |
| S E Ilyin, D Gayle, I González-Gómez, M E Miele, C R Plata-Salamá. Brain tumor development in rats is associated with changes in central nervous system cytokine and neuropeptide systems. Brain research bulletin. vol 48. issue 4. 1999-07-23. PMID:10357067. |
brain tumor formation was associated with significant increased levels of interleukin (il)-1beta, il-1 receptor antagonist, il-1 receptor type i, tumor necrosis factor (tnf)-alpha, and transforming growth factor (tgf)-beta1 mrnas in the cerebellum, hippocampus, and hypothalamus. |
1999-07-23 |
2023-08-12 |
rat |
| C Gu, A Castellino, J Y Chan, M V Cha. BRE: a modulator of TNF-alpha action. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 12. issue 12. 1998-09-29. PMID:9737713. |
here we report that bre was identified multiple times in a yeast two-hybrid screen of a murine cerebellar cdna library, using the juxtamembrane domain of the p55 tumor necrosis factor alpha (tnf) receptor. |
1998-09-29 |
2023-08-12 |
human |
| S E Ilyin, D Gayle, M C Flynn, C R Plata-Salamá. Interleukin-1beta system (ligand, receptor type I, receptor accessory protein and receptor antagonist), TNF-alpha, TGF-beta1 and neuropeptide Y mRNAs in specific brain regions during bacterial LPS-induced anorexia. Brain research bulletin. vol 45. issue 5. 1998-06-09. PMID:9570721. |
administration of lps on mrna levels of interleukin-1beta (il-1beta) system components, tumor necrosis factor (tnf)-alpha, transforming growth factor (tgf)-beta1, and neuropeptide y (npy) in the cerebellum, hippocampus, and hypothalamus. |
1998-06-09 |
2023-08-12 |
rat |
| G Farkas, J Márton, Z Nagy, Y Mándi, T Takács, M A Deli, C S Abrahá. Experimental acute pancreatitis results in increased blood-brain barrier permeability in the rat: a potential role for tumor necrosis factor and interleukin 6. Neuroscience letters. vol 242. issue 3. 1998-05-14. PMID:9530927. |
cytokine concentrations were measured in bioassays with specific cell lines (wehi-164 for tnf and b-9 for il-6), while the bbb permeability was determined for a small (sodium fluorescein, molecular weight (mw) 376 da), and a large (evans' blue-albumin, mw 67000 da) tracer by spectrophotometry in the parietal cortex, hippocampus, striatum, cerebellum and medulla of rats. |
1998-05-14 |
2023-08-12 |
rat |