| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anne E Sumner, Jane L Harman, Sarah G Buxbaum, Bernard V Miller, Anita V Tambay, Sharon B Wyatt, Herman A Taylor, Charles N Rotimi, Daniel F Sarpon. The triglyceride/high-density lipoprotein cholesterol ratio fails to predict insulin resistance in African-American women: an analysis of Jackson Heart Study. Metabolic syndrome and related disorders. vol 8. issue 6. 2011-03-31. PMID:20715971. |
screening programs that could identify insulin resistance early enough for intervention to affect outcome often rely on triglyceride (tg) and high-density lipoprotein cholesterol (hdl-c) levels. |
2011-03-31 |
2023-08-12 |
Not clear |
| Liliana Karabatas, Maria Eugenia Oliva, Eduardo Dascal, Gustavo J Hein, Claudia Pastorale, Adriana Chicco, Yolanda B Lombardo, Juan C Basab. Is Lipotoxicity presents in the early stages of an experimental model of autoimmune diabetes? Further studies in the multiple low dose of streptozotocin model. Islets. vol 2. issue 3. 2011-03-31. PMID:21099313. |
we analyzed the temporal changes of: (1) plasma and skeletal muscle lipids and their relationship with glucose metabolism; (2) triglyceride (tg) concentration in isolated islets; (3) intraperitoneal glucose tolerance test; and (4) insulin secretion patterns when the three mutually interactive glucose signaling pathways were activated. |
2011-03-31 |
2023-08-12 |
mouse |
| Liliana Karabatas, Maria Eugenia Oliva, Eduardo Dascal, Gustavo J Hein, Claudia Pastorale, Adriana Chicco, Yolanda B Lombardo, Juan C Basab. Is Lipotoxicity presents in the early stages of an experimental model of autoimmune diabetes? Further studies in the multiple low dose of streptozotocin model. Islets. vol 2. issue 3. 2011-03-31. PMID:21099313. |
(2) plasma tg, glucose and insulin levels and glucose tolerance test were significantly different only after day 8. |
2011-03-31 |
2023-08-12 |
mouse |
| Selwyn Lewis Cox, Jessica Stolp, Nicole L Hallahan, Jacqueline Counotte, Wenyu Zhang, David V Serreze, Antony Basten, Pablo A Silveir. Enhanced responsiveness to T-cell help causes loss of B-lymphocyte tolerance to a β-cell neo-self-antigen in type 1 diabetes prone NOD mice. European journal of immunology. vol 40. issue 12. 2011-03-24. PMID:21108464. |
to shed light on the mechanisms responsible for the breakdown in b-lymphocyte self-tolerance to β-cell ag, we utilised a model whereby hen-egg lysozyme (hel)-specific ig tg (ighel-tg)-tg b lymphocytes were allowed to develop in or were transferred into mice expressing the hel tg under an insulin promoter (inshel-tg). |
2011-03-24 |
2023-08-12 |
mouse |
| Jasvinder Singh Bhatti, G K Bhatti, S S Mastana, S Ralhan, A Joshi, R Tewar. ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes in North Indians. Molecular and cellular biochemistry. vol 345. issue 1-2. 2011-03-23. PMID:20820885. |
no significant correlation among the bmi, whr, bp, tg, tc, hdl-c, ldl-c, glucose, hba1c, creatinine, and insulin indices (homa-ir) was observed in the individuals carrying kk and kq genotypes. |
2011-03-23 |
2023-08-12 |
human |
| Jahid Zabuli, Tomomi Tanaka, Wengeng Lu, Hideo Kamoma. Intermittent nutritional stimulus by short-term treatment of high-energy diet promotes ovarian performance together with increases in blood levels of glucose and insulin in cycling goats. Animal reproduction science. vol 122. issue 3-4. 2011-03-18. PMID:20961717. |
mean plasma concentrations of glucose and insulin were significantly (p<0.05) higher in the tg than in the cg on almost all days during each treatment period. |
2011-03-18 |
2023-08-12 |
Not clear |
| Alireza Esteghamati, Ali Zandieh, Omid Khalilzadeh, Afsaneh Morteza, Alipasha Meysamie, Manouchehr Nakhjavani, Mohammad Mehdi Gouy. Clustering of leptin and physical activity with components of metabolic syndrome in Iranian population: an exploratory factor analysis. Endocrine. vol 38. issue 2. 2011-03-08. PMID:21046482. |
performing factor analysis on waist circumference, homeostasis model assessment of insulin resistance, systolic blood pressure, triglycerides (tg) and high-density lipoprotein cholesterol (hdl-c) led to extraction of two factors which explained around 59.0% of the total variance in both genders. |
2011-03-08 |
2023-08-12 |
Not clear |
| Giuseppe Derosa, Pamela Maffioli, Ilaria Ferrari, Angela D'Angelo, Elena Fogari, Ilaria Palumbo, Sabrina Randazzo, Arrigo F G Cicer. Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients. Endocrine journal. vol 57. issue 9. 2011-02-11. PMID:20683173. |
we evaluated at baseline, and after 3, 6, 9, and 12 months these parameters: body weight, body mass index (bmi), hba(1c), fasting plasma glucose (fpg), post-prandial plasma glucose (ppg), fasting plasma insulin (fpi), homeostasis model assessment insulin resistance index (homa-ir), total cholesterol (tc), low density lipoprotein-cholesterol (ldl-c), high density lipoprotein-cholesterol (hdl-c), triglycerides (tg), retinol binding protein-4 (rbp-4), resistin, visfatin, high sensitivity-c reactive protein (hs-crp). |
2011-02-11 |
2023-08-12 |
Not clear |
| Yun-Xia Lu, Qiu Zhang, Jun Li, Yu-Xiu Sun, Ling-Yun Wang, Wen-Ming Cheng, Xiang-Yang H. Antidiabetic effects of total flavonoids from Litsea Coreana leve on fat-fed, streptozotocin-induced type 2 diabetic rats. The American journal of Chinese medicine. vol 38. issue 4. 2011-01-19. PMID:20626057. |
treatment with tflc showed a significant increase in insulin sensitivity, serum hdl-c level and sod activities, meanwhile marked decrease in body weight, serum ffa, tc, tg, ldl-c, crp, mda content. |
2011-01-19 |
2023-08-12 |
rat |
| J Mark Brown, Jenna L Betters, Caleb Lord, Yinyan Ma, Xianlin Han, Kui Yang, Heather M Alger, John Melchior, Janet Sawyer, Ramesh Shah, Martha D Wilson, Xiuli Liu, Mark J Graham, Richard Lee, Rosanne Crooke, Gerald I Shulman, Bingzhong Xue, Hang Shi, Liqing Y. CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance. Journal of lipid research. vol 51. issue 11. 2011-01-19. PMID:20802159. |
these hepatic lipid alterations were associated with significant decreases in hepatic tg hydrolase activity, hepatic lipoprotein-tg secretion, and plasma concentrations of ketones, nonesterified fatty acids, and insulin. |
2011-01-19 |
2023-08-12 |
mouse |
| Go Yamada, Hiroyuki Ariyasu, Hiroshi Iwakura, Hiroshi Hosoda, Takashi Akamizu, Kazuwa Nakao, Kenji Kangaw. Generation of transgenic mice overexpressing a ghrelin analog. Endocrinology. vol 151. issue 12. 2011-01-04. PMID:20962048. |
however, 1-yr-old tg mice demonstrated impaired glucose tolerance and reduced insulin sensitivity. |
2011-01-04 |
2023-08-12 |
mouse |
| Xian-sheng Huang, Shui-Ping Zhao, Min Hu, Lin Bai, Qian Zhang, Wang Zha. Decreased apolipoprotein A5 is implicated in insulin resistance-related hypertriglyceridemia in obesity. Atherosclerosis. vol 210. issue 2. 2010-12-06. PMID:20047745. |
in addition, treatment of hepg2 cells with insulin and tnfalpha decreased apoa5 expression and increased tg content. |
2010-12-06 |
2023-08-12 |
human |
| Giovanni Musso, Roberto Gambino, Maurizio Cassade. Lipoprotein metabolism mediates the association of MTP polymorphism with beta-cell dysfunction in healthy subjects and in nondiabetic normolipidemic patients with nonalcoholic steatohepatitis. The Journal of nutritional biochemistry. vol 21. issue 9. 2010-11-24. PMID:19733470. |
despite comparable insulin resistance, fasting lipids, adipokines and dietary habits, mtp gg genotype had significantly more severe beta-cell dysfunction; higher plasma tg, ffa, intestinal and hepatic very low-density lipoprotein 1 subfractions and oxldl responses and deeper hdl-c fall than gt/tt carriers in patients and controls. |
2010-11-24 |
2023-08-12 |
human |
| Sandra O Hernández-González, Manuel González-Ortiz, Esperanza Martínez-Abundis, José A Robles-Cervante. Chitosan improves insulin sensitivity as determined by the euglycemic-hyperinsulinemic clamp technique in obese subjects. Nutrition research (New York, N.Y.). vol 30. issue 6. 2010-11-04. PMID:20650346. |
in conclusion, 3-month administration of chitosan increased insulin sensitivity in obese patients and demonstrated a decrease in weight, body mass index, waist circumference, and tg. |
2010-11-04 |
2023-08-12 |
human |
| Dinesh Gautam, Inigo Ruiz de Azua, Jian Hua Li, Jean-Marc Guettier, Thomas Heard, Yinghong Cui, Huiyan Lu, William Jou, Oksana Gavrilova, Walter S Zawalich, Jürgen Wes. Beneficial metabolic effects caused by persistent activation of beta-cell M3 muscarinic acetylcholine receptors in transgenic mice. Endocrinology. vol 151. issue 11. 2010-11-04. PMID:20843999. |
in the presence of 15 mm glucose and the absence of m3r ligands, isolated perifused islets prepared from β-m3-q490l tg mice released considerably more insulin than wild-type control islets. |
2010-11-04 |
2023-08-12 |
mouse |
| Dinesh Gautam, Inigo Ruiz de Azua, Jian Hua Li, Jean-Marc Guettier, Thomas Heard, Yinghong Cui, Huiyan Lu, William Jou, Oksana Gavrilova, Walter S Zawalich, Jürgen Wes. Beneficial metabolic effects caused by persistent activation of beta-cell M3 muscarinic acetylcholine receptors in transgenic mice. Endocrinology. vol 151. issue 11. 2010-11-04. PMID:20843999. |
in vivo studies showed that β-m3-q490l tg mice displayed greatly improved glucose tolerance and increased serum insulin levels as well as resistance to diet-induced glucose intolerance and hyperglycemia. |
2010-11-04 |
2023-08-12 |
mouse |
| Gilberto Campos, Virginia Fernández, Erika Fernández, Emperatriz Molero, Luz Marina Morales, Xiomara Raleigh, Lissette Connell, Elena Ryde. Association of free fatty acids with the insulin-resistant state but not with central obesity in individuals from Venezuela. Investigacion clinica. vol 51. issue 1. 2010-11-02. PMID:20815161. |
basal concentrations of tg, total cholesterol, ldl-c, and hdl-c were measured, and ffa, glucose and insulin, at basal state and at different times after a glucose load. |
2010-11-02 |
2023-08-12 |
human |
| Bela F Asztalos, Michael M Swarbrick, Ernst J Schaefer, Gerard E Dallal, Katalin V Horvath, Masumi Ai, Kimber L Stanhope, Iselin Austrheim-Smith, Bruce M Wolfe, Mohamed Ali, Peter J Have. Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women. Journal of lipid research. vol 51. issue 8. 2010-10-20. PMID:20631298. |
standard lipids, remnant-lipoprotein cholesterol (rlp-c); hdl-triglyceride (tg); apolipoproteins (apo) a-i, a-ii, e, and a-i-containing hdl subpopulations; lecithin-cholesterol acyltransferase (lcat) and cholesteryl ester transfer protein (cetp) mass and activity; plasma glucose and insulin levels were measured before and at 1, 3, 6, and 12 months after gbp surgery. |
2010-10-20 |
2023-08-12 |
Not clear |
| Bela F Asztalos, Michael M Swarbrick, Ernst J Schaefer, Gerard E Dallal, Katalin V Horvath, Masumi Ai, Kimber L Stanhope, Iselin Austrheim-Smith, Bruce M Wolfe, Mohamed Ali, Peter J Have. Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women. Journal of lipid research. vol 51. issue 8. 2010-10-20. PMID:20631298. |
baseline concentrations of tg, rlp-c, glucose, and insulin were significantly higher in obese than in normal-weight, age-matched women, whereas hdl cholesterol (hdl-c), apoa-i, apoa-ii, alpha-1 and alpha-2 levels were significantly lower. |
2010-10-20 |
2023-08-12 |
Not clear |
| Bela F Asztalos, Michael M Swarbrick, Ernst J Schaefer, Gerard E Dallal, Katalin V Horvath, Masumi Ai, Kimber L Stanhope, Iselin Austrheim-Smith, Bruce M Wolfe, Mohamed Ali, Peter J Have. Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women. Journal of lipid research. vol 51. issue 8. 2010-10-20. PMID:20631298. |
over 1 year, significant decreases of body mass index, glucose, insulin, tg, rlp-c, hdl-tg, and prebeta-1 levels were observed with significant increases of hdl-c and alpha-1 levels (all p < 0.05). |
2010-10-20 |
2023-08-12 |
Not clear |